{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T08:38:07Z","timestamp":1771663087942,"version":"3.50.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871811"],"award-info":[{"award-number":["81871811"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1007\/s10067-021-05722-7","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T04:04:03Z","timestamp":1621310643000},"page":"3951-3960","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Identification of prognostic factors and construction of a nomogram for patients with relapse\/refractory adult-onset Still\u2019s disease"],"prefix":"10.1007","volume":"40","author":[{"given":"Ruxue","family":"Yin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gangjian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaopei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuolin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianfang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3197-3158","authenticated-orcid":false,"given":"Shengyun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,18]]},"reference":[{"issue":"10","key":"5722_CR1","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1016\/j.autrev.2017.07.017","volume":"16","author":"M Govoni","year":"2017","unstructured":"Govoni M, Bortoluzzi A, Rossi D, Modena V (2017) How I treat patients with adult onset Still's disease in clinical practice. Autoimmun Rev 16(10):1016\u20131023. https:\/\/doi.org\/10.1016\/j.autrev.2017.07.017","journal-title":"Autoimmun Rev"},{"issue":"23","key":"5722_CR2","doi-asserted-by":"publisher","first-page":"2856","DOI":"10.1097\/cm9.0000000000000538","volume":"132","author":"MY Wang","year":"2019","unstructured":"Wang MY, Jia JC, Yang CD, Hu QY (2019) Pathogenesis, disease course, and prognosis of adult-onset Still's disease: an update and review. Chin Med J 132(23):2856\u20132864. https:\/\/doi.org\/10.1097\/cm9.0000000000000538","journal-title":"Chin Med J"},{"issue":"2","key":"5722_CR3","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1002\/art.1780300209","volume":"30","author":"JJ Cush","year":"1987","unstructured":"Cush JJ, Medsger TA Jr, Christy WC, Herbert DC, Cooperstein LA (1987) Adult-onset Still's disease. Clinical course and outcome. Arthritis Rheum 30(2):186\u2013194. https:\/\/doi.org\/10.1002\/art.1780300209","journal-title":"Arthritis Rheum"},{"issue":"1","key":"5722_CR4","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1186\/s12916-016-0738-8","volume":"14","author":"P Ruscitti","year":"2016","unstructured":"Ruscitti P, Cipriani P, Masedu F, Iacono D, Ciccia F, Liakouli V, Guggino G, Carubbi F, Berardicurti O, Di Benedetto P, Valenti M, Triolo G, Valentini G, Giacomelli R (2016) Adult-onset Still\u2019s disease: evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers. BMC Med 14(1):194. https:\/\/doi.org\/10.1186\/s12916-016-0738-8","journal-title":"BMC Med"},{"issue":"3","key":"5722_CR5","doi-asserted-by":"publisher","first-page":"401","DOI":"10.3109\/14397595.2014.973659","volume":"25","author":"N Nishina","year":"2015","unstructured":"Nishina N, Kaneko Y, Kameda H, Takeuchi T (2015) The effect of tocilizumab on preventing relapses in adult-onset Still's disease: a retrospective, single-center study. Mod Rheumatol 25(3):401\u2013404. https:\/\/doi.org\/10.3109\/14397595.2014.973659","journal-title":"Mod Rheumatol"},{"issue":"9","key":"5722_CR6","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1007\/s10067-010-1516-1","volume":"29","author":"XD Kong","year":"2010","unstructured":"Kong XD, Xu D, Zhang W, Zhao Y, Zeng X, Zhang F (2010) Clinical features and prognosis in adult-onset Still's disease: a study of 104 cases. Clin Rheumatol 29(9):1015\u20131019. https:\/\/doi.org\/10.1007\/s10067-010-1516-1","journal-title":"Clin Rheumatol"},{"issue":"6","key":"5722_CR7","first-page":"23","volume":"37","author":"Y Takakuwa","year":"2019","unstructured":"Takakuwa Y, Hanaoka H, Kiyokawa T, Iida H, Ishimori K, Uekusa T, Yamada H, Kawahata K (2019) Adult-onset Still\u2019s disease-associated interstitial lung disease represents severe phenotype of the disease with higher rate of haemophagocytic syndrome and relapse. Clin Exp Rheumatol 37 Suppl 121(6):23\u201327","journal-title":"Clin Exp Rheumatol"},{"issue":"3","key":"5722_CR8","first-page":"424","volume":"19","author":"M Yamaguchi","year":"1992","unstructured":"Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, Kashiwazaki S, Tanimoto K, Matsumoto Y, Ota T et al (1992) Preliminary criteria for classification of adult Still's disease. J Rheumatol 19(3):424\u2013430","journal-title":"J Rheumatol"},{"issue":"2","key":"5722_CR9","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1136\/ard.2004.024026","volume":"64","author":"B Fautrel","year":"2005","unstructured":"Fautrel B, Sibilia J, Mariette X, Combe B (2005) Tumour necrosis factor alpha blocking agents in refractory adult Still\u2019s disease: an observational study of 20 cases. Ann Rheum Dis 64(2):262\u2013266. https:\/\/doi.org\/10.1136\/ard.2004.024026","journal-title":"Ann Rheum Dis"},{"issue":"23","key":"5722_CR10","doi-asserted-by":"publisher","first-page":"2577","DOI":"10.1002\/sim.5328","volume":"31","author":"OV Demler","year":"2012","unstructured":"Demler OV, Pencina MJ, D'Agostino RB Sr (2012) Misuse of DeLong test to compare AUCs for nested models. Stat Med 31(23):2577\u20132587. https:\/\/doi.org\/10.1002\/sim.5328","journal-title":"Stat Med"},{"key":"5722_CR11","doi-asserted-by":"crossref","unstructured":"Qiu MJ, Yang SL, Wang MM, Li YN, Jiang X, Huang ZZ, Xiong ZF (2020) Prognostic evaluation of esophageal cancer patients with stages I-III. Aging 12. 10.18632\/aging.103532","DOI":"10.18632\/aging.103532"},{"issue":"6","key":"5722_CR12","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1177\/0272989x06295361","volume":"26","author":"AJ Vickers","year":"2006","unstructured":"Vickers AJ, Elkin EB (2006) Decision curve analysis: a novel method for evaluating prediction models. Medical decision making : an international journal of the Society for Medical Decision Making 26(6):565\u2013574. https:\/\/doi.org\/10.1177\/0272989x06295361","journal-title":"Medical decision making : an international journal of the Society for Medical Decision Making"},{"issue":"1-2","key":"5722_CR13","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1007\/s12026-014-8561-9","volume":"61","author":"Y Jamilloux","year":"2015","unstructured":"Jamilloux Y, Gerfaud-Valentin M, Martinon F, Belot A, Henry T, S\u00e8ve P (2015) Pathogenesis of adult-onset Still's disease: new insights from the juvenile counterpart. Immunol Res 61(1-2):53\u201362. https:\/\/doi.org\/10.1007\/s12026-014-8561-9","journal-title":"Immunol Res"},{"issue":"2","key":"5722_CR14","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1097\/md.0000000000000021","volume":"93","author":"M Gerfaud-Valentin","year":"2014","unstructured":"Gerfaud-Valentin M, Maucort-Boulch D, Hot A, Iwaz J, Ninet J, Durieu I, Broussolle C, S\u00e8ve P (2014) Adult-onset still disease: manifestations, treatment, outcome, and prognostic factors in 57 patients. Medicine 93(2):91\u201399. https:\/\/doi.org\/10.1097\/md.0000000000000021","journal-title":"Medicine"},{"issue":"2","key":"5722_CR15","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1136\/ard.30.2.121","volume":"30","author":"EG Bywaters","year":"1971","unstructured":"Bywaters EG (1971) Still\u2019s disease in the adult. Ann Rheum Dis 30(2):121\u2013133. https:\/\/doi.org\/10.1136\/ard.30.2.121","journal-title":"Ann Rheum Dis"},{"key":"5722_CR16","doi-asserted-by":"publisher","unstructured":"Wang J, Chu Y, Li J, Zeng F, Wu M, Wang T, Sun L, Chen Q, Wang P, Zhang X, Zeng F (2020) Development of a prediction model with serum tumor markers to assess tumor metastasis in lung cancer. 9 (15):5436-5445. https:\/\/doi.org\/10.1002\/cam4.3184","DOI":"10.1002\/cam4.3184"},{"issue":"29","key":"5722_CR17","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000007546","volume":"96","author":"JY Seo","year":"2017","unstructured":"Seo JY, Suh CH, Jung JY, Kim AR, Yang JW, Kim HA (2017) The neutrophil-to-lymphocyte ratio could be a good diagnostic marker and predictor of relapse in patients with adult-onset Still\u2019s disease: a STROBE-compliant retrospective observational analysis. Medicine 96(29):e7546. https:\/\/doi.org\/10.1097\/md.0000000000007546","journal-title":"Medicine"},{"issue":"5","key":"5722_CR18","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1007\/s00296-011-1801-6","volume":"32","author":"HA Kim","year":"2012","unstructured":"Kim HA, Sung JM, Suh CH (2012) Therapeutic responses and prognosis in adult-onset Still's disease. Rheumatol Int 32(5):1291\u20131298. https:\/\/doi.org\/10.1007\/s00296-011-1801-6","journal-title":"Rheumatol Int"},{"key":"5722_CR19","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jaut.2018.07.018","volume":"93","author":"R Giacomelli","year":"2018","unstructured":"Giacomelli R, Ruscitti P, Shoenfeld Y (2018) A comprehensive review on adult onset Still\u2019s disease. J Autoimmun 93:24\u201336. https:\/\/doi.org\/10.1016\/j.jaut.2018.07.018","journal-title":"J Autoimmun"},{"key":"5722_CR20","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.jaut.2016.02.010","volume":"69","author":"U Kalyoncu","year":"2016","unstructured":"Kalyoncu U, Solmaz D, Emmungil H, Yazici A, Kasifoglu T, Kimyon G, Balkarli A, Bes C, Ozmen M, Alibaz-Oner F, Erten S, Cagatay Y, Cetin GY, Yilmaz S, Yildiz F, Pamuk ON, Kucuksahin O, Kilic L, Yazisiz V, Karadag O, Koca SS, Hayran M, Akar S, Aksu K, Akkoc N, Keser G, Gonullu E, Kisacik B, Onat AM, Soy M, Inanc N, Direskeneli H, Sayarlioglu M, Erken E, Turgay M, Cefle A, Ertenli I, Pay S (2016) Response rate of initial conventional treatments, disease course, and related factors of patients with adult-onset Still\u2019s disease: data from a large multicenter cohort. J Autoimmun 69:59\u201363. https:\/\/doi.org\/10.1016\/j.jaut.2016.02.010","journal-title":"J Autoimmun"},{"issue":"3","key":"5722_CR21","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.blre.2008.08.001","volume":"23","author":"MA Knovich","year":"2009","unstructured":"Knovich MA, Storey JA, Coffman LG, Torti SV, Torti FM (2009) Ferritin for the clinician. Blood Rev 23(3):95\u2013104. https:\/\/doi.org\/10.1016\/j.blre.2008.08.001","journal-title":"Blood Rev"},{"issue":"07","key":"5722_CR22","first-page":"415","volume":"11","author":"YX Lei","year":"2007","unstructured":"Lei YX, Yang XY, Zhang X, Qiu Q, Lian F, Liang LQ, Xu HS (2007) A study of prognosis in adult onset Still\u2019s disease patients. Chinese Journal of Rheumatology 11(07):415\u2013417","journal-title":"Chinese Journal of Rheumatology"},{"issue":"4","key":"5722_CR23","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1007\/s00018-009-0205-1","volume":"67","author":"JW Semple","year":"2010","unstructured":"Semple JW, Freedman J (2010) Platelets and innate immunity. Cellular and molecular life sciences : CMLS 67(4):499\u2013511. https:\/\/doi.org\/10.1007\/s00018-009-0205-1","journal-title":"Cellular and molecular life sciences : CMLS"},{"issue":"24","key":"5722_CR24","doi-asserted-by":"publisher","first-page":"2482","DOI":"10.1056\/NEJMra071014","volume":"357","author":"G Dav\u00ec","year":"2007","unstructured":"Dav\u00ec G, Patrono C (2007) Platelet activation and atherothrombosis. N Engl J Med 357(24):2482\u20132494. https:\/\/doi.org\/10.1056\/NEJMra071014","journal-title":"N Engl J Med"},{"issue":"5965","key":"5722_CR25","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1126\/science.1181928","volume":"327","author":"E Boilard","year":"2010","unstructured":"Boilard E, Nigrovic PA, Larabee K, Watts GF, Coblyn JS, Weinblatt ME, Massarotti EM, Remold-O'Donnell E, Farndale RW, Ware J, Lee DM (2010) Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science (New York, NY) 327(5965):580\u2013583. https:\/\/doi.org\/10.1126\/science.1181928","journal-title":"Science (New York, NY)"},{"key":"5722_CR26","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/j.1749-6632.1981.tb29717.x","volume":"370","author":"JM Riddle","year":"1981","unstructured":"Riddle JM, Bluhm GB, Pitchford WC, McElroy H, Jimenea C, Leisen J, Venkatasubramanian K (1981) A comparative study of platelet reactivity in arthritis. Ann N Y Acad Sci 370:22\u201329. https:\/\/doi.org\/10.1111\/j.1749-6632.1981.tb29717.x","journal-title":"Ann N Y Acad Sci"},{"issue":"7534","key":"5722_CR27","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/s0140-6736(68)92718-9","volume":"1","author":"CH Bolton","year":"1968","unstructured":"Bolton CH, Hampton JR, Phillipson OT (1968) Platelet behaviour and plasma phospholipids in multiple sclerosis. Lancet (London, England) 1(7534):99\u2013104. https:\/\/doi.org\/10.1016\/s0140-6736(68)92718-9","journal-title":"Lancet (London, England)"},{"issue":"3","key":"5722_CR28","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1136\/jnnp.29.3.187","volume":"29","author":"JH Millar","year":"1966","unstructured":"Millar JH, Merrett JD, Dalby AM (1966) Platelet stickiness in multiple sclerosis. J Neurol Neurosurg Psychiatry 29(3):187\u2013189. https:\/\/doi.org\/10.1136\/jnnp.29.3.187","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"8","key":"5722_CR29","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1002\/ibd.20896","volume":"15","author":"H Yoshida","year":"2009","unstructured":"Yoshida H, Granger DN (2009) Inflammatory bowel disease: a paradigm for the link between coagulation and inflammation. Inflamm Bowel Dis 15(8):1245\u20131255. https:\/\/doi.org\/10.1002\/ibd.20896","journal-title":"Inflamm Bowel Dis"},{"issue":"12","key":"5722_CR30","doi-asserted-by":"publisher","first-page":"3180","DOI":"10.3748\/wjg.v20.i12.3180","volume":"20","author":"E Voudoukis","year":"2014","unstructured":"Voudoukis E, Karmiris K, Koutroubakis IE (2014) Multipotent role of platelets in inflammatory bowel diseases: a clinical approach. World J Gastroenterol 20(12):3180\u20133190. https:\/\/doi.org\/10.3748\/wjg.v20.i12.3180","journal-title":"World J Gastroenterol"},{"issue":"3","key":"5722_CR31","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3109\/14397595.2014.974881","volume":"25","author":"YF Asanuma","year":"2015","unstructured":"Asanuma YF, Mimura T, Tsuboi H, Noma H, Miyoshi F, Yamamoto K, Sumida T (2015) Nationwide epidemiological survey of 169 patients with adult Still's disease in Japan. Mod Rheumatol 25(3):393\u2013400. https:\/\/doi.org\/10.3109\/14397595.2014.974881","journal-title":"Mod Rheumatol"},{"issue":"7","key":"5722_CR32","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1007\/s10067-016-3308-8","volume":"35","author":"P Sfriso","year":"2016","unstructured":"Sfriso P, Priori R, Valesini G, Rossi S, Montecucco CM, D'Ascanio A, Carli L, Bombardieri S, LaSelva G, Iannone F, Lapadula G, Alivernini S, Ferraccioli G, Colaci M, Ferri C, Iacono D, Valentini G, Costa L, Scarpa R, LoMonaco A, Bagnari V, Govoni M, Piazza I, Adami S, Ciccia F, Triolo G, Alessandri E, Cutolo M, Cantarini L, Galeazzi M, Ruscitti P, Giacomelli R, Caso F, Galozzi P, Punzi L (2016) Adult-onset Still's disease: an Italian multicentre retrospective observational study of manifestations and treatments in 245 patients. Clin Rheumatol 35(7):1683\u20131689. https:\/\/doi.org\/10.1007\/s10067-016-3308-8","journal-title":"Clin Rheumatol"},{"issue":"4","key":"5722_CR33","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1080\/14712598.2019.1590334","volume":"19","author":"S Casta\u00f1eda","year":"2019","unstructured":"Casta\u00f1eda S, Mart\u00ednez-Quintanilla D, Mart\u00edn-Varillas JL, Garc\u00eda-Casta\u00f1eda N, Atienza-Mateo B, Gonz\u00e1lez-Gay MA (2019) Tocilizumab for the treatment of adult-onset Still\u2019s disease. Expert Opin Biol Ther 19(4):273\u2013286. https:\/\/doi.org\/10.1080\/14712598.2019.1590334","journal-title":"Expert Opin Biol Ther"},{"issue":"8","key":"5722_CR34","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1007\/s00296-020-04622-4","volume":"40","author":"M Reihl Crnogaj","year":"2020","unstructured":"Reihl Crnogaj M, \u010cubeli\u0107 D (2020) Treatment of refractory adult onset. Still\u2019s disease with tocilizumab-a single centre experience and literature review 40(8):1317\u20131325. https:\/\/doi.org\/10.1007\/s00296-020-04622-4","journal-title":"Still\u2019s disease with tocilizumab-a single centre experience and literature review"},{"issue":"4","key":"5722_CR35","doi-asserted-by":"publisher","first-page":"1793","DOI":"10.1016\/j.jtcvs.2017.12.107","volume":"155","author":"SY Park","year":"2018","unstructured":"Park SY (2018) Nomogram: an analogue tool to deliver digital knowledge. J Thorac Cardiovasc Surg 155(4):1793. https:\/\/doi.org\/10.1016\/j.jtcvs.2017.12.107","journal-title":"J Thorac Cardiovasc Surg"}],"updated-by":[{"DOI":"10.1007\/s10067-021-05856-8","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000}}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-021-05722-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10067-021-05722-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-021-05722-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T22:01:59Z","timestamp":1632520919000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10067-021-05722-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,18]]},"references-count":35,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["5722"],"URL":"https:\/\/doi.org\/10.1007\/s10067-021-05722-7","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s10067-021-05856-8","asserted-by":"object"}]},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,18]]},"assertion":[{"value":"10 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 March 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2021","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10067-021-05856-8","URL":"https:\/\/doi.org\/10.1007\/s10067-021-05856-8","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study complies with the Declaration of Helsinki, and all procedures performed in the study were in accordance with the ethical standards of the institutional research committee.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}