{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:17:25Z","timestamp":1791839845645,"version":"4.3.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"OHSU WheelsUp Program","award":["3T32HL094294-08S1"],"award-info":[{"award-number":["3T32HL094294-08S1"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1007\/s10067-021-05768-7","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T23:07:13Z","timestamp":1621292833000},"page":"3963-3969","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Inflammatory arthritis-associated pyoderma gangrenosum: a systematic review"],"prefix":"10.1007","volume":"40","author":[{"given":"Erika","family":"Sawka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emile","family":"Latour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex G.","family":"Ortega-Loayza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,18]]},"reference":[{"issue":"6","key":"5768_CR1","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1111\/j.1365-2133.2011.10565.x","volume":"165","author":"AM Binus","year":"2011","unstructured":"Binus AM, Qureshi AA, Li VW, Winterfield LS (2011) Pyoderma gangrenosum: a retrospective review of patient characteristics, comorbidities and therapy in 103 patients. Br J Dermatol 165(6):1244\u20131250. https:\/\/doi.org\/10.1111\/j.1365-2133.2011.10565.x","journal-title":"Br J Dermatol"},{"issue":"1","key":"5768_CR2","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1111\/j.1365-2249.2010.04201.x","volume":"162","author":"AV Marzano","year":"2010","unstructured":"Marzano AV, Cugno M, Trevisan V et al (2010) Role of inflammatory cells, cytokines and matrix metalloproteinases in neutrophil-mediated skin diseases. Clin Exp Immunol 162(1):100\u2013107. https:\/\/doi.org\/10.1111\/j.1365-2249.2010.04201.x","journal-title":"Clin Exp Immunol"},{"issue":"6","key":"5768_CR3","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1177\/0141076814534407","volume":"107","author":"A Teagle","year":"2014","unstructured":"Teagle A, Hargest R (2014) Management of pyoderma gangrenosum. J R Soc Med 107(6):228\u2013236. https:\/\/doi.org\/10.1177\/0141076814534407","journal-title":"J R Soc Med"},{"issue":"6","key":"5768_CR4","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s00403-019-01912-1","volume":"311","author":"LJ Borda","year":"2019","unstructured":"Borda LJ, Wong LL, Marzano AV, Ortega-Loayza AG (2019) Extracutaneous involvement of pyoderma gangrenosum. Arch Dermatol Res 311(6):425\u2013434. https:\/\/doi.org\/10.1007\/s00403-019-01912-1","journal-title":"Arch Dermatol Res"},{"issue":"4","key":"5768_CR5","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s40257-018-0356-7","volume":"19","author":"K Kridin","year":"2018","unstructured":"Kridin K, Cohen AD, Amber KT (2018) Underlying systemic diseases in pyoderma gangrenosum: a systematic review and meta-analysis. Am J Clin Dermatol 19(4):479\u2013487. https:\/\/doi.org\/10.1007\/s40257-018-0356-7","journal-title":"Am J Clin Dermatol"},{"issue":"2","key":"5768_CR6","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s10067-020-05253-7","volume":"40","author":"K Kridin","year":"2021","unstructured":"Kridin K, Damiani G, Cohen AD (2021) Rheumatoid arthritis and pyoderma gangrenosum: a population-based case-control study. Clin Rheumatol 40(2):521\u2013528. https:\/\/doi.org\/10.1007\/s10067-020-05253-7","journal-title":"Clin Rheumatol"},{"issue":"1","key":"5768_CR7","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/ajg.2010.343","volume":"106","author":"SR Vavricka","year":"2011","unstructured":"Vavricka SR, Brun L, Ballabeni P, Pittet V, PrinzVavricka BM, Zeitz J, Rogler G, Schoepfer AM (2011) Frequency and risk factors for extraintestinal manifestations in the Swiss inflammatory bowel disease cohort. Am J Gastroenterol 106(1):110\u2013119. https:\/\/doi.org\/10.1038\/ajg.2010.343","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"5768_CR8","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1001\/jamadermatol.2017.5978","volume":"154","author":"HJ Ashchyan","year":"2018","unstructured":"Ashchyan HJ, Butler DC, Nelson CA et al (2018) JAMA dermatology original investigation the association of age with clinical presentation and comorbidities of pyoderma gangrenosum. JAMA Dermatol 154(4):409\u2013413. https:\/\/doi.org\/10.1001\/jamadermatol.2017.5978","journal-title":"JAMA Dermatol"},{"issue":"2","key":"5768_CR9","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.jaad.2004.10.006","volume":"53","author":"J Reichrath","year":"2005","unstructured":"Reichrath J, Bens G, Bonowitz A, Tilgen W (2005) Treatment recommendations for pyoderma gangrenosum: an evidence-based review of the literature based on more than 350 patients. J Am Acad Dermatol 53(2):273\u2013283. https:\/\/doi.org\/10.1016\/j.jaad.2004.10.006","journal-title":"J Am Acad Dermatol"},{"issue":"7","key":"5768_CR10","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1001\/archderm.140.7.861","volume":"140","author":"CA Charles","year":"2004","unstructured":"Charles CA, Bialy TL, Falabella AF, Eaglstein WH, Kerdel FA, Kirsner RS (2004) Poor prognosis of arthritis-associated pyoderma gangrenosum. Arch Dermatol 140(7):861\u2013864. https:\/\/doi.org\/10.1001\/archderm.140.7.861","journal-title":"Arch Dermatol"},{"issue":"3","key":"5768_CR11","doi-asserted-by":"publisher","first-page":"191","DOI":"10.2340\/00015555-2008","volume":"13","author":"I Ahronowitz","year":"2012","unstructured":"Ahronowitz I, Harp J, Shinkai K (2012) Etiology and management of pyoderma gangrenosum: a comprehensive review. Am J Clin Dermatol 13(3):191\u2013211. https:\/\/doi.org\/10.2340\/00015555-2008","journal-title":"Am J Clin Dermatol"},{"issue":"3","key":"5768_CR12","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1111\/j.1365-2230.2010.03941.x","volume":"36","author":"RM Bhat","year":"2011","unstructured":"Bhat RM, Nandakishore B, Sequeira FF et al (2011) Pyoderma gangrenosum: an Indian perspective. Clin Exp Dermatol 36(3):242\u2013247. https:\/\/doi.org\/10.1111\/j.1365-2230.2010.03941.x","journal-title":"Clin Exp Dermatol"},{"issue":"2","key":"5768_CR13","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1097\/00005792-198003000-00003","volume":"59","author":"PJ Holt","year":"1980","unstructured":"Holt PJ, Davies MG, Saunder KC, Nuki G (1980) Pyoderma gangrenosum: clinical and laboratory findings in 15 patients with special reference to polyarthritis. Medicine (Baltimore) 59(2):114\u2013133","journal-title":"Medicine (Baltimore)"},{"issue":"217","key":"5768_CR14","first-page":"173","volume":"55","author":"FC Powell","year":"1985","unstructured":"Powell FC, Schroeter AL, Su WP, Perry HO (1985) Pyoderma gangrenosum: a review of 86 patients. Q J Med 55(217):173\u2013186","journal-title":"Q J Med"},{"issue":"9","key":"5768_CR15","doi-asserted-by":"publisher","first-page":"2166","DOI":"10.1038\/jid.2012.130","volume":"132","author":"SM Langan","year":"2012","unstructured":"Langan SM, Groves RW, Card TR, Gulliford MC (2012) Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study. J Invest Dermatol 132(9):2166\u20132170. https:\/\/doi.org\/10.1038\/jid.2012.130","journal-title":"J Invest Dermatol"},{"issue":"2","key":"5768_CR16","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.jaad.2004.07.023","volume":"53","author":"A Sayah","year":"2005","unstructured":"Sayah A, English JC (2005) Rheumatoid arthritis: a review of the cutaneous manifestations. J Am Acad Dermatol 53(2):191\u2013209. https:\/\/doi.org\/10.1016\/j.jaad.2004.07.023","journal-title":"J Am Acad Dermatol"},{"issue":"9","key":"5768_CR17","doi-asserted-by":"publisher","first-page":"2247","DOI":"10.1007\/s00277-019-03732-9","volume":"98","author":"AS Gupta","year":"2019","unstructured":"Gupta AS, Ortega-Loayza AG (2019) Pyoderma gangrenosum: a too often overlooked facultative paraneoplastic disease. Ann Hematol 98(9):2247\u20132248. https:\/\/doi.org\/10.1007\/s00277-019-03732-9","journal-title":"Ann Hematol"},{"issue":"6","key":"5768_CR18","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1111\/j.1365-2133.1997.tb01568.x","volume":"137","author":"P Von den Driesch","year":"1997","unstructured":"Von den Driesch P (1997) Pyoderma gangrenosum: a report of 44 cases with follow-up. Br J Dermatol 137(6):1000\u20131005","journal-title":"Br J Dermatol"},{"key":"5768_CR19","doi-asserted-by":"publisher","first-page":"h2958","DOI":"10.1136\/bmj.h2958","volume":"350","author":"AD Ormerod","year":"2015","unstructured":"Ormerod AD, Thomas KS, Craig FE et al (2015) Comparison of the two most commonly used treatments for pyoderma gangrenosum: results of the STOP GAP randomised controlled trial. BMJ 350:h2958. https:\/\/doi.org\/10.1136\/bmj.h2958","journal-title":"BMJ"},{"issue":"1","key":"5768_CR20","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1097\/MOH.0000000000000100","volume":"22","author":"D Maalouf","year":"2015","unstructured":"Maalouf D, Battistella M, Bouaziz JD (2015) Neutrophilic dermatosis: disease mechanism and treatment. Curr Opin Hematol 22(1):23\u201329. https:\/\/doi.org\/10.1097\/MOH.0000000000000100","journal-title":"Curr Opin Hematol"},{"issue":"4","key":"5768_CR21","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1136\/gut.2005.074815","volume":"55","author":"TN Brooklyn","year":"2006","unstructured":"Brooklyn TN, Dunnill MGS, Shetty A et al (2006) Infliximab for the treatment of pyoderma gangrenosum: a randomised, double blind, placebo controlled trial. Gut 55(4):505\u2013509. https:\/\/doi.org\/10.1136\/gut.2005.074815","journal-title":"Gut"},{"issue":"1","key":"5768_CR22","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1111\/cei.12394","volume":"178","author":"AV Marzano","year":"2014","unstructured":"Marzano AV, Fanoni D, Antiga E et al (2014) Expression of cytokines, chemokines and other effector molecules in two prototypic autoinflammatory skin diseases, pyoderma gangrenosum and sweet\u2019s syndrome. Clin Exp Immunol 178(1):48\u201356. https:\/\/doi.org\/10.1111\/cei.12394","journal-title":"Clin Exp Immunol"},{"issue":"13\u201314","key":"5768_CR23","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s10354-014-0285-x","volume":"164","author":"U Wollina","year":"2014","unstructured":"Wollina U, Tchernev G (2014) Pyoderma gangrenosum: pathogenetic oriented treatment approaches. Wien Med Wochenschr 164(13\u201314):263\u2013273. https:\/\/doi.org\/10.1007\/s10354-014-0285-x","journal-title":"Wien Med Wochenschr"},{"issue":"2","key":"5768_CR24","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s12016-017-8629-0","volume":"54","author":"M Cugno","year":"2018","unstructured":"Cugno M, Gualtierotti R, Meroni PL, Marzano AV (2018) Inflammatory joint disorders and neutrophilic dermatoses: a comprehensive review. Clin Rev Allergy Immunol 54(2):269\u2013281. https:\/\/doi.org\/10.1007\/s12016-017-8629-0","journal-title":"Clin Rev Allergy Immunol"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-021-05768-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10067-021-05768-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-021-05768-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T22:01:14Z","timestamp":1632520874000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10067-021-05768-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,18]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["5768"],"URL":"https:\/\/doi.org\/10.1007\/s10067-021-05768-7","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,18]]},"assertion":[{"value":"15 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}