{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T17:46:52Z","timestamp":1791481612156,"version":"4.3.4"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1007\/s10067-024-07133-w","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T15:03:19Z","timestamp":1725894199000},"page":"3577-3580","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Three cases of relapsed eosinophilic sinusitis without eosinophilia during mepolizumab maintenance therapy for eosinophilic granulomatosis with polyangiitis"],"prefix":"10.1007","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1604-5249","authenticated-orcid":false,"given":"Kazuma","family":"Nishisaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6065-8486","authenticated-orcid":false,"given":"Yo","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mie","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3638-5366","authenticated-orcid":false,"given":"Masaaki","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8054-7847","authenticated-orcid":false,"given":"Goichi","family":"Kageyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7606-3743","authenticated-orcid":false,"given":"Jun","family":"Saegusa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"issue":"6","key":"7133_CR1","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1038\/s41584-023-00958-w","volume":"19","author":"G Emmi","year":"2023","unstructured":"Emmi G, Bettiol A, Gelain E, Bajema IM, Berti A, Burns S et al (2023) Evidence-based guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis. Nat Rev Rheumatol 19(6):378\u2013393. https:\/\/doi.org\/10.1038\/s41584-023-00958-w","journal-title":"Nat Rev Rheumatol"},{"issue":"1","key":"7133_CR2","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1080\/1744666X.2019.1697678","volume":"16","author":"A Berti","year":"2020","unstructured":"Berti A, Boukhlal S, Groh M, Cornec D (2020) Eosinophilic granulomatosis with polyangiitis: the multifaceted spectrum of clinical manifestations at different stages of the disease. Expert Rev Clin Immunol 16(1):51\u201361. https:\/\/doi.org\/10.1080\/1744666X.2019.1697678","journal-title":"Expert Rev Clin Immunol"},{"issue":"4","key":"7133_CR3","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1007\/s10067-018-4062-x","volume":"37","author":"S Suwanchote","year":"2018","unstructured":"Suwanchote S, Rachayon M, Rodsaward P, Wongpiyabovorn J, Deekajorndech T, Wright HL et al (2018) Anti-neutrophil cytoplasmic antibodies and their clinical significance. Clin Rheumatol 37(4):875\u2013884. https:\/\/doi.org\/10.1007\/s10067-018-4062-x","journal-title":"Clin Rheumatol"},{"issue":"20","key":"7133_CR4","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1056\/NEJMoa1702079","volume":"376","author":"ME Wechsler","year":"2017","unstructured":"Wechsler ME, Akuthota P, Jayne D, Khoury P, Klion A, Langford CA et al (2017) Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis. N Engl J Med 376(20):1921\u20131932. https:\/\/doi.org\/10.1056\/NEJMoa1702079","journal-title":"N Engl J Med"},{"issue":"1","key":"7133_CR5","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s13075-023-03097-5","volume":"25","author":"T Yamane","year":"2023","unstructured":"Yamane T, Hashiramoto A (2023) Mepolizumab exerts crucial effects on glucocorticoid discontinuation in patients with eosinophilic granulomatosis with polyangiitis: a retrospective study of 27 cases at a single center in Japan. Arthritis Res Ther 25(1):110. https:\/\/doi.org\/10.1186\/s13075-023-03097-5","journal-title":"Arthritis Res Ther"},{"issue":"2","key":"7133_CR6","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1097\/00005792-198403000-00001","volume":"63","author":"JG Lanham","year":"1984","unstructured":"Lanham JG, Elkon KB, Pusey CD, Hughes GR (1984) Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome. Medicine (Baltimore) 63(2):65\u201381. https:\/\/doi.org\/10.1097\/00005792-198403000-00001","journal-title":"Medicine (Baltimore)"},{"issue":"8","key":"7133_CR7","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1002\/art.1780330806","volume":"33","author":"AT Masi","year":"1990","unstructured":"Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP et al (1990) The American college of rheumatology 1990 criteria for the classification of churg-strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum 33(8):1094\u20131100. https:\/\/doi.org\/10.1002\/art.1780330806","journal-title":"Arthritis Rheum"},{"issue":"3","key":"7133_CR8","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1136\/annrheumdis-2021-221794","volume":"81","author":"PC Grayson","year":"2022","unstructured":"Grayson PC, Ponte C, Suppiah R, Robson JC, Craven A, Judge A et al (2022) 2022 American college of rheumatology\/european alliance of associations for rheumatology classification criteria for eosinophilic granulomatosis with polyangiitis. Ann Rheum Dis 81(3):309\u2013314. https:\/\/doi.org\/10.1136\/annrheumdis-2021-221794","journal-title":"Ann Rheum Dis"},{"key":"7133_CR9","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/S0065-2776(08)01003-1","volume":"101","author":"C Blanchard","year":"2009","unstructured":"Blanchard C, Rothenberg ME (2009) Biology of the eosinophil. Adv Immunol 101:81\u2013121. https:\/\/doi.org\/10.1016\/S0065-2776(08)01003-1","journal-title":"Adv Immunol"},{"key":"7133_CR10","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1196\/annals.1361.053","volume":"1051","author":"B Hellmich","year":"2005","unstructured":"Hellmich B, Csernok E, Gross WL (2005) Proinflammatory cytokines and autoimmunity in Churg-Strauss syndrome. Ann N Y Acad Sci 1051:121\u2013131. https:\/\/doi.org\/10.1196\/annals.1361.053","journal-title":"Ann N Y Acad Sci"},{"issue":"10","key":"7133_CR11","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1093\/rheumatology\/kes171","volume":"51","author":"B Jakiela","year":"2012","unstructured":"Jakiela B, Szczeklik W, Plutecka H, Sokolowska B, Mastalerz L, Sanak M et al (2012) Increased production of IL-5 and dominant Th2-type response in airways of Churg-Strauss syndrome patients. Rheumatology (Oxford) 51(10):1887\u20131893. https:\/\/doi.org\/10.1093\/rheumatology\/kes171","journal-title":"Rheumatology (Oxford)"},{"issue":"6","key":"7133_CR12","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1016\/j.jaci.2010.03.028","volume":"125","author":"S Kim","year":"2010","unstructured":"Kim S, Marigowda G, Oren E, Israel E, Wechsler ME (2010) Mepolizumab as a steroid-sparing treatment option in patients with Churg-Strauss syndrome. J Allergy Clin Immunol 125(6):1336\u20131343. https:\/\/doi.org\/10.1016\/j.jaci.2010.03.028","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl S29","key":"7133_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4193\/Rhin20.600","volume":"58","author":"WJ Fokkens","year":"2020","unstructured":"Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S et al (2020) European position paper on rhinosinusitis and nasal polyps 2020. Rhinology 58(Suppl S29):1\u2013464. https:\/\/doi.org\/10.4193\/Rhin20.600","journal-title":"Rhinology"},{"key":"7133_CR14","doi-asserted-by":"publisher","unstructured":"Grayson JW, Hopkins C, Mori E, Senior B, Harvey RJ (2020) Contemporary classification of chronic rhinosinusitis beyond polyps vs no polyps: a review. JAMA Otolaryngol Head Neck Surg. 2020 Sep 1;146(9):831\u2013838. https:\/\/doi.org\/10.1001\/jamaoto.2020.1453. Erratum in: JAMA Otolaryngol Head Neck Surg 146(9):876. https:\/\/doi.org\/10.1001\/jamaoto.2020.2776","DOI":"10.1001\/jamaoto.2020.1453 10.1001\/jamaoto.2020.2776"},{"issue":"5","key":"7133_CR15","doi-asserted-by":"publisher","first-page":"1949","DOI":"10.1007\/s10067-020-05474-w","volume":"40","author":"G Contro","year":"2021","unstructured":"Contro G, Brescia G, Alessandrini L, Barion U, Padoan R, Frigo AC et al (2021) Neutrophil infiltrates and eosinophil aggregates in chronic rhinosinusitis with nasal polyps and EGPA. Clin Rheumatol 40(5):1949\u20131957. https:\/\/doi.org\/10.1007\/s10067-020-05474-w","journal-title":"Clin Rheumatol"},{"issue":"4","key":"7133_CR16","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1084\/jem.20141671","volume":"212","author":"LE Cheng","year":"2015","unstructured":"Cheng LE, Sullivan BM, Retana LE, Allen CD, Liang HE, Locksley RM (2015) IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function. J Exp Med 212(4):513\u2013524. https:\/\/doi.org\/10.1084\/jem.20141671","journal-title":"J Exp Med"},{"issue":"5","key":"7133_CR17","doi-asserted-by":"publisher","first-page":"445","DOI":"10.2500\/ajr.2006.20.0796","volume":"20","author":"L Petecchia","year":"2006","unstructured":"Petecchia L, Serpero L, Silvestri M, Sabatini F, Scarso L, Rossi GA (2006) The histamine-induced enhanced expression of vascular cell adhesion molecule-1 by nasal polyp-derived fibroblasts is inhibited by levocetirizine. Am J Rhinol 20(5):445\u20139. https:\/\/doi.org\/10.2500\/ajr.2006.20.0796","journal-title":"Am J Rhinol"},{"issue":"12","key":"7133_CR18","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1080\/00016480701242444","volume":"127","author":"M Nonaka","year":"2007","unstructured":"Nonaka M, Fukumoto A, Ogihara N, Pawankar R, Sakanushi A, Yagi T (2007) Expression of MCP-4 by TLR ligand-stimulated nasal polyp fibroblasts. Acta Otolaryngol 127(12):1304\u20131309. https:\/\/doi.org\/10.1080\/00016480701242444","journal-title":"Acta Otolaryngol"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-024-07133-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10067-024-07133-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-024-07133-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T09:05:05Z","timestamp":1729242305000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10067-024-07133-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,9]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["7133"],"URL":"https:\/\/doi.org\/10.1007\/s10067-024-07133-w","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,9]]},"assertion":[{"value":"31 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 August 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}},{"value":"Patients and\/or the public were not involved in the design, conduct, reporting, or dissemination plans of this research.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Consent obtained directly from patient(s).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Not commissioned; externally peer reviewed.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Provenance and peer review"}}]}}