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All patients had Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, bilateral knee radiography, and ultrasonography. Inter-observer reliability of ultrasound was evaluated in 30 knees by another newly trained operator.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Most of the OMERACT-US KOA scores showed significant associations with WOMAC clinical scores, except for femoral cartilage damage and effusion. The synovitis score was significantly associated with WOMAC\u2013pain score (<jats:italic>p<\/jats:italic>-value 0.046), while medial meniscus extrusion (MME) and medial osteophytes were significantly associated with WOMAC\u2013stiffness score (<jats:italic>p<\/jats:italic>-value 0.009 and 0.023, respectively). MME and synovitis were significantly associated with WOMAC\u2013physical score (<jats:italic>p<\/jats:italic>-value 0.035 and 0.020, respectively). The ultrasound scores also showed a strong correlation with radiographic scoring. Inter-observer reliability ranged from moderate to excellent agreement (<jats:italic>k<\/jats:italic>\u2009=\u20090.58 to <jats:italic>k<\/jats:italic>\u2009=\u20090.83); it was highest for lateral osteophytes (<jats:italic>k<\/jats:italic>\u2009=\u20090.83), good agreement for synovitis (<jats:italic>k<\/jats:italic>\u2009=\u20090.72), any osteophytes (<jats:italic>k<\/jats:italic>\u2009=\u20090.71), damage of femoral cartilage (<jats:italic>k<\/jats:italic>\u2009=\u20090.70), and moderate agreement for medial osteophytes (<jats:italic>k<\/jats:italic>\u2009=\u20090.58) and MME (<jats:italic>k<\/jats:italic>\u2009=\u20090.59).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>OMERACT-US scoring system for KOA demonstrated validity, reliability, and feasibility for evaluating both structural and inflammatory components. Using cutoff values improved the scoring reliability for osteophytes and MME.\n<jats:table-wrap><jats:table><jats:tbody>\n                      <jats:tr>\n                        <jats:td colspan=\"2\"><jats:bold>Key Points<\/jats:bold><jats:italic>\u2022 OMERACT-US scores provide a valid assessment of inflammatory and structural components of knee osteoarthritis.<\/jats:italic><jats:italic>\u2022 The following changes may improve the performance of the OMERACT-US scores.<\/jats:italic>a. <jats:italic>The binary score for effusion and synovial hypertrophy can be omitted, as they have no added value.<\/jats:italic>b. <jats:italic>A semi-quantitative grading for effusion may capture the impact of effusion on clinical outcomes.<\/jats:italic>c. <jats:italic>Added cutoff values to score medial meniscal extrusion, osteophytes, and pathological effusion improved the respective scores\u2019 reliability.<\/jats:italic>d. <jats:italic>Applying the updated OMERACT definition of synovitis.<\/jats:italic><jats:italic>\u2022 OMERACT-US scores are reliable to be used with a newly trained operator, particularly when cutoff values are included, and proper training time is provided.<\/jats:italic><jats:italic>\u2022 The OMERACT-US score is feasible to be used in clinical practice, as the time taken to perform was short, even for a newly trained operator.<\/jats:italic><\/jats:td>\n                      <\/jats:tr>\n                    <\/jats:tbody><\/jats:table><\/jats:table-wrap><\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10067-024-07171-4","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T06:02:08Z","timestamp":1729231328000},"page":"3913-3923","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Assessment of validity, reliability, and feasibility of OMERACT ultrasound knee osteoarthritis scores in Egyptian patients with primary knee osteoarthritis"],"prefix":"10.1007","volume":"43","author":[{"given":"Manal Abd El Moniem El","family":"Menyawi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galila","family":"Gamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoda","family":"Abdelbadie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4002-1485","authenticated-orcid":false,"given":"Rasmia","family":"Elgohary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,18]]},"reference":[{"key":"7171_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/genes11080854","volume":"11","author":"D Primorac","year":"2020","unstructured":"Primorac D, Molnar V, Rod E, Jele\u010d \u017d, \u010cukelj F, Mati\u0161i\u0107 V et al (2020) Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations. 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