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Diagrams 2 and 3 have been updated.","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2026","order":9,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":10,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":11,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10067-026-08351-0","URL":"https:\/\/doi.org\/10.1007\/s10067-026-08351-0","order":12,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The experimental protocol was reviewed and approved by the Animal Research and Care Committee of Tongji Medical College, Huazhong University of Science and Technology (SCKK (XIONG) 12\u201301-2024\u2013TJH-202402079). The study is reported by ARRIVE guidelines (\n                      \n                      ). This trial was registered with\u00a0ClinicalTrials.gov, number\u00a0NCT10203935. Registered October 07, 2023.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}