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Demographic, clinical, comorbidities, and laboratory data were collected. Hyperuricemia threshold\u2009\u2265\u200960 mg\/L.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>There were no significant differences between patients with and without hyperuricemia regarding gender, PsA articular subtype, PASI score, and treatment received, while patients with hyperuricemia were older (40.47\u2009\u00b1\u20098.53 vs 34.59\u2009\u00b1\u20097.29, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001), had more comorbidity, higher body mass index (BMI) (28.49\u2009\u00b1\u20092.07 vs 26.91\u2009\u00b1\u20091.63kg\/m2, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001), DAPSA score (16.75\u2009\u00b1\u20097.04 vs 9.32\u2009\u00b1\u20096.35, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001), ESR (34.78\u2009\u00b1\u20097.12 vs 28.55\u2009\u00b1\u20098.97, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001), CRP (11.42\u2009\u00b1\u20093.23 vs 8.68\u2009\u00b1\u20094.04, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001), serum cholesterol (220.42\u2009\u00b1\u200946.83 vs 169.82\u2009\u00b1\u200937.82, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001), and triglycerides (136.47\u2009\u00b1\u200936.4 vs 104.89\u2009\u00b1\u200922.15, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001), and longer duration of Psoriasis and PsA. The serum uric acid levels were significantly positively correlated with age, duration of Psoriasis, duration of PsA, BMI, CRP, ESR, DAPSA, and PASI score. Multivariate analysis showed that male sex, BMI, and increased disease activity were independent predictors of hyperuricemia in PsA patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Psoriatic arthritis patients with hyperuricemia have higher age, BMI, disease activity, and more associated comorbidities. In PsA patients, hyperuricemia was associated with male sex, BMI, and increased disease activity, but not associated with PASI score.<\/jats:p>\n            <jats:p>\n              <jats:table-wrap>\n                <jats:table>\n                  <jats:tbody>\n                    <jats:tr>\n                      <jats:td align=\"left\" colspan=\"2\">\n                        <jats:bold>Key Points<\/jats:bold>\u2022 <jats:italic>Psoriasis, PsA, and hyperurice s is a bi-centric case\u2013control retrospective of cardiovascular disease.<\/jats:italic>\u2022 <jats:italic>Male gender, BMI, and increased disease activity were independent predictors of hyperuricemia in PsA patients.<\/jats:italic>\n                        <jats:italic>\u2022 Psoriatic arthritis patients with hyperuricemia have been more associated with comorbidities.<\/jats:italic>\n                      <\/jats:td>\n                    <\/jats:tr>\n                  <\/jats:tbody>\n                <\/jats:table>\n              <\/jats:table-wrap>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s10067-025-07400-4","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T03:48:47Z","timestamp":1743997727000},"page":"2321-2326","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Hyperuricemia in psoriatic arthritis: clinical correlations and implications"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6414-5602","authenticated-orcid":false,"given":"Samar AbdAlhamed","family":"Tabra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5024-2516","authenticated-orcid":false,"given":"Hany M.","family":"Aly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5823-422X","authenticated-orcid":false,"given":"Saad","family":"Ghanem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8436-8598","authenticated-orcid":false,"given":"Mohammed Hassan","family":"Abu-Zaid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"7400_CR1","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1002\/art.24608","volume":"61","author":"G Ibrahim","year":"2009","unstructured":"Ibrahim G, Waxman R, Helliwell PS (2009) The prevalence of psoriatic arthritis in people with psoriasis. 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