{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T20:17:39Z","timestamp":1771964259516,"version":"3.50.1"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s10067-025-07423-x","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T02:58:07Z","timestamp":1745809087000},"page":"2241-2256","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Investigation of hub-shared genes and regulatory mechanisms of rheumatoid arthritis and atherosclerosis"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4660-4875","authenticated-orcid":false,"given":"Pei","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kexin","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhipeng","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yueqing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanqing","family":"Tie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"issue":"10","key":"7423_CR1","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1038\/s41584-022-00827-y","volume":"18","author":"A Finckh","year":"2022","unstructured":"Finckh A, Gilbert B, Hodkinson B, Bae S-C, Thomas R, Deane KD, Alpizar-Rodriguez D, Lauper K (2022) Global epidemiology of rheumatoid arthritis. Nat Rev Rheumatol 18(10):591\u2013602. https:\/\/doi.org\/10.1038\/s41584-022-00827-y","journal-title":"Nat Rev Rheumatol"},{"key":"7423_CR2","doi-asserted-by":"crossref","unstructured":"Padyukov L: Genetics of rheumatoid arthritis. In: Seminars in immunopathology: 2022: Springer; 2022: 47\u201362.","DOI":"10.1007\/s00281-022-00912-0"},{"issue":"2","key":"7423_CR3","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.berh.2018.10.005","volume":"32","author":"D van der Woude","year":"2018","unstructured":"van der Woude D, van der Helm-van AH (2018) Update on the epidemiology, risk factors, and disease outcomes of rheumatoid arthritis. Best Pract Res Clin Rheumatol 32(2):174\u2013187","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"3","key":"7423_CR4","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1097\/BOR.0000000000000267","volume":"28","author":"M Dougados","year":"2016","unstructured":"Dougados M (2016) Comorbidities in rheumatoid arthritis. Curr Opin Rheumatol 28(3):282\u2013288","journal-title":"Curr Opin Rheumatol"},{"issue":"3","key":"7423_CR5","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1097\/MOL.0000000000000302","volume":"27","author":"F Schaftenaar","year":"2016","unstructured":"Schaftenaar F, Frodermann V, Kuiper J, Lutgens E (2016) Atherosclerosis: the interplay between lipids and immune cells. Curr Opin Lipidol 27(3):209\u2013215","journal-title":"Curr Opin Lipidol"},{"issue":"7908","key":"7423_CR6","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1038\/s41586-022-04673-6","volume":"605","author":"SK Mohanta","year":"2022","unstructured":"Mohanta SK, Peng L, Li Y, Lu S, Sun T, Carnevale L, Perrotta M, Ma Z, F\u00f6rstera B, Stanic K (2022) Neuroimmune cardiovascular interfaces control atherosclerosis. Nature 605(7908):152\u2013159","journal-title":"Nature"},{"issue":"10","key":"7423_CR7","doi-asserted-by":"publisher","first-page":"1630","DOI":"10.1016\/j.cell.2022.04.004","volume":"185","author":"JL Bj\u00f6rkegren","year":"2022","unstructured":"Bj\u00f6rkegren JL, Lusis AJ (2022) Atherosclerosis: recent developments. Cell 185(10):1630\u201345","journal-title":"Cell"},{"key":"7423_CR8","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1146\/annurev-med-060911-090007","volume":"64","author":"JM Kahlenberg","year":"2013","unstructured":"Kahlenberg JM, Kaplan MJ (2013) Mechanisms of premature atherosclerosis in rheumatoid arthritis and lupus. Annu Rev Med 64:249\u2013263","journal-title":"Annu Rev Med"},{"issue":"7","key":"7423_CR9","first-page":"460","volume":"21","author":"M Adawi","year":"2019","unstructured":"Adawi M, Firas S, Blum A (2019) Rheumatoid arthritis and atherosclerosis. Israel Medic Assoc J: IMAJ 21(7):460\u2013463","journal-title":"Israel Medic Assoc J: IMAJ"},{"issue":"7","key":"7423_CR10","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/s41584-023-00969-7","volume":"19","author":"BN Weber","year":"2023","unstructured":"Weber BN, Giles JT, Liao KP (2023) Shared inflammatory pathways of rheumatoid arthritis and atherosclerotic cardiovascular disease. Nature Rev Rheumatol 19(7):417\u201328","journal-title":"Nature Rev Rheumatol"},{"issue":"7","key":"7423_CR11","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1038\/nrrheum.2015.40","volume":"11","author":"S Skeoch","year":"2015","unstructured":"Skeoch S, Bruce IN (2015) Atherosclerosis in rheumatoid arthritis: is it all about inflammation? Nat Rev Rheumatol 11(7):390\u2013400","journal-title":"Nat Rev Rheumatol"},{"key":"7423_CR12","doi-asserted-by":"publisher","first-page":"828933","DOI":"10.3389\/fphar.2022.828933","volume":"13","author":"J Wang","year":"2022","unstructured":"Wang J, He L, Li W, Lv S (2022) A role of IL-17 in rheumatoid arthritis patients complicated with atherosclerosis. Front Pharmacol 13:828933","journal-title":"Front Pharmacol"},{"issue":"1","key":"7423_CR13","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1002\/acr.23094","volume":"69","author":"K Jafri","year":"2017","unstructured":"Jafri K, Bartels CM, Shin D, Gelfand JM, Ogdie A (2017) Incidence and management of cardiovascular risk factors in psoriatic arthritis and rheumatoid arthritis: a population-based study. Arthritis Care Res 69(1):51\u201357","journal-title":"Arthritis Care Res"},{"issue":"13","key":"7423_CR14","doi-asserted-by":"publisher","first-page":"988479","DOI":"10.3389\/fimmu.2022.988479","volume":"23","author":"H Fang","year":"2022","unstructured":"Fang H, Sun Z, Chen Z, Chen A, Sun D, Kong Y, Fang H, Qian G (2022) Bioinformatics and systems-biology analysis to determine the effects of Coronavirus disease 2019 on patients with allergic asthma. Front Immunol 23(13):988479","journal-title":"Front Immunol"},{"issue":"13","key":"7423_CR15","doi-asserted-by":"publisher","first-page":"1008653","DOI":"10.3389\/fimmu.2022.1008653","volume":"28","author":"C Yan","year":"2022","unstructured":"Yan C, Niu Y, Wang X (2022) Blood transcriptome analysis revealed the crosstalk between COVID-19 and HIV. Front Immunol 28(13):1008653","journal-title":"Front Immunol"},{"issue":"suppl_1","key":"7423_CR16","first-page":"D562","volume":"33","author":"T Barrett","year":"2005","unstructured":"Barrett T, Suzek TO, Troup DB, Wilhite SE, Ngau WC, Ledoux P, Rudnev D, Lash AE, Fujibuchi W, Edgar R (2005) NCBI GEO: mining millions of expression profiles\u2014database and tools. Nucleic Acids Res. 33(suppl_1):D562-6","journal-title":"Nucleic Acids Res."},{"issue":"43","key":"7423_CR17","doi-asserted-by":"publisher","first-page":"15545","DOI":"10.1073\/pnas.0506580102","volume":"102","author":"A Subramanian","year":"2005","unstructured":"Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci 102(43):15545\u201315550","journal-title":"Proc Natl Acad Sci"},{"key":"7423_CR18","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/0-387-29362-0_23","volume-title":"Bioinformatics and computational biology solutions using R and bioconductor","author":"GK Smyth","year":"2005","unstructured":"Smyth GK (2005) Limma: linear models for microarray data. Bioinformatics and computational biology solutions using R and bioconductor. Springer, NewYork, pp 397\u2013420"},{"issue":"1","key":"7423_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2105-9-559","volume":"9","author":"P Langfelder","year":"2008","unstructured":"Langfelder P, Horvath S (2008) WGCNA: an R package for weighted correlation network analysis. BMC Bioinformat 9(1):1\u201313","journal-title":"BMC Bioinformat"},{"issue":"5","key":"7423_CR20","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","volume":"16","author":"G Yu","year":"2012","unstructured":"Yu G, Wang LG, Han Y, He QY (2012) clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS J Integr Biol 16(5):284\u2013287","journal-title":"OMICS J Integr Biol"},{"issue":"1","key":"7423_CR21","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/75556","volume":"25","author":"M Ashburner","year":"2000","unstructured":"Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT (2000) Gene ontology: tool for the unification of biology. Nat Genet 25(1):25\u201329","journal-title":"Nat Genet"},{"issue":"1","key":"7423_CR22","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","volume":"28","author":"M Kanehisa","year":"2000","unstructured":"Kanehisa M, Goto S (2000) KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28(1):27\u201330","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"7423_CR23","doi-asserted-by":"publisher","first-page":"D362","DOI":"10.1093\/nar\/gkw937","volume":"45","author":"D Szklarczyk","year":"2017","unstructured":"Szklarczyk D, Morris JH, Cook H, Kuhn M, Wyder S, Simonovic M, Santos A, Doncheva NT, Roth A, Bork P, Jensen LJ, von Mering C (2017) The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. Nucleic Acids Res 45(D1):D362\u2013D368. https:\/\/doi.org\/10.1093\/nar\/gkw937","journal-title":"Nucleic Acids Res"},{"issue":"11","key":"7423_CR24","doi-asserted-by":"publisher","first-page":"2498","DOI":"10.1101\/gr.1239303","volume":"13","author":"P Shannon","year":"2003","unstructured":"Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13(11):2498\u20132504","journal-title":"Genome Res"},{"issue":"4","key":"7423_CR25","first-page":"1","volume":"8","author":"C-H Chin","year":"2014","unstructured":"Chin C-H, Chen S-H, Wu H-H, Ho C-W, Ko M-T, Lin C-Y (2014) cytoHubba: identifying hub objects and sub-networks from complex interactome. BMC Syst Biol 8(4):1\u20137","journal-title":"BMC Syst Biol"},{"issue":"1","key":"7423_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2105-12-77","volume":"12","author":"X Robin","year":"2011","unstructured":"Robin X, Turck N, Hainard A, Tiberti N, Lisacek F, Sanchez J-C, M\u00fcller M (2011) pROC: an open-source package for R and S+ to analyze and compare ROC curves. BMC Bioinformat 12(1):1\u20138","journal-title":"BMC Bioinformat"},{"issue":"suppl_2","key":"7423_CR27","doi-asserted-by":"publisher","first-page":"W214","DOI":"10.1093\/nar\/gkq537","volume":"38","author":"D Warde-Farley","year":"2010","unstructured":"Warde-Farley D, Donaldson SL, Comes O, Zuberi K, Badrawi R, Chao P, Franz M, Grouios C, Kazi F, Lopes CT (2010) The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acid Res 38(suppl_2):W214\u2013W220","journal-title":"Nucleic Acid Res"},{"issue":"7","key":"7423_CR28","doi-asserted-by":"publisher","first-page":"e1003731","DOI":"10.1371\/journal.pcbi.1003731","volume":"10","author":"J Rs","year":"2014","unstructured":"Rs J (2014) Verfaillie A, Imrichov\u00e1 H, Van de Sande B, Standaert L, Christiaens V, Hulselmans G, Herten K, Naval Sanchez M, Potier D: iRegulon: from a gene list to a gene regulatory network using large motif and track collections. PLoS Comput Biol 10(7):e1003731","journal-title":"PLoS Comput Biol"},{"issue":"suppl_1","key":"7423_CR29","doi-asserted-by":"publisher","first-page":"D668","DOI":"10.1093\/nar\/gkj067","volume":"34","author":"DS Wishart","year":"2006","unstructured":"Wishart DS, Knox C, Guo AC, Shrivastava S, Hassanali M, Stothard P, Chang Z, Woolsey J (2006) DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acid Res 34(suppl_1):D668\u2013D672","journal-title":"Nucleic Acid Res"},{"key":"7423_CR30","first-page":"243","volume-title":"Profiling tumor infiltrating immune cells with CIBERSORT","author":"B Chen","year":"2018","unstructured":"Chen B, Khodadoust MS, Liu CL, Newman AM, Alizadeh AA (2018) Profiling tumor infiltrating immune cells with CIBERSORT. Methods and Protocols, Cancer Systems Biology, pp 243\u201359"},{"key":"7423_CR31","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.intimp.2018.03.002","volume":"59","author":"K Vijay","year":"2018","unstructured":"Vijay K (2018) Toll-like receptors in immunity and inflammatory diseases: past, present, and future. Int Immunopharmacol 59:391\u2013412","journal-title":"Int Immunopharmacol"},{"issue":"11","key":"7423_CR32","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/j.molmed.2007.09.002","volume":"13","author":"T Kawai","year":"2007","unstructured":"Kawai T, Akira S (2007) Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med 13(11):460\u2013469","journal-title":"Trends Mol Med"},{"issue":"3","key":"7423_CR33","doi-asserted-by":"publisher","first-page":"973","DOI":"10.62347\/TPOQ4910","volume":"16","author":"Z Zhu","year":"2024","unstructured":"Zhu Z, Wan L (2024) Exploration of the molecular mechanism guiding Xinfeng capsule regulatory mechanism for rheumatoid arthritis inflammation. Am J Transl Res 16(3):973\u2013987","journal-title":"Am J Transl Res"},{"issue":"2","key":"7423_CR34","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1080\/1744666X.2024.2392815","volume":"21","author":"FS Tabatabaei","year":"2025","unstructured":"Tabatabaei FS, Shafeghat M, Azimi A, Akrami A, Rezaei N (2025) Endosomal Toll-Like Receptors intermediate negative impacts of viral diseases, autoimmune diseases, and inflammatory immune responses on the cardiovascular system. Expert Rev Clinic Immunol 21(2):195\u2013207","journal-title":"Expert Rev Clinic Immunol"},{"issue":"8","key":"7423_CR35","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1038\/s12276-024-01281-4","volume":"56","author":"Y Cao","year":"2024","unstructured":"Cao Y, Chen M, Jiao X, Li S, Wang D, Zhan Y, Li J, Hao Z, Li Q, Liu Y et al (2024) Neutrophil extracellular traps mediate the crosstalk between plaque microenvironment and unstable carotid plaque formation. Exp Mol Med 56(8):1717\u20131735","journal-title":"Exp Mol Med"},{"issue":"3","key":"7423_CR36","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.clim.2006.05.006","volume":"120","author":"T Watanabe","year":"2006","unstructured":"Watanabe T (2006) Masuyama J-i, Sohma Y, Inazawa H, Horie K, Kojima K, Uemura Y, Aoki Y, Kaga S, Minota S: CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells. Clin Immunol 120(3):247\u2013259","journal-title":"Clin Immunol"},{"issue":"2","key":"7423_CR37","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1038\/cdd.2017.173","volume":"25","author":"M Rashidi","year":"2018","unstructured":"Rashidi M, Bandala-Sanchez E, Lawlor KE, Zhang Y, Neale AM, Vijayaraj SL, O\u2019Donoghue R, Wentworth JM, Adams TE, Vince JE et al (2018) CD52 inhibits Toll-like receptor activation of NF-\u03baB and triggers apoptosis to suppress inflammation. Cell Death Differ 25(2):392\u2013405","journal-title":"Cell Death Differ"},{"key":"7423_CR38","doi-asserted-by":"publisher","first-page":"988266","DOI":"10.3389\/fcvm.2022.988266","volume":"9","author":"W Li","year":"2022","unstructured":"Li W, Jin K, Luo J, Xu W, Wu Y, Zhou J, Wang Y, Xu R, Jiao L, Wang T (2022) NF-\u03baB and its crosstalk with endoplasmic reticulum stress in atherosclerosis. Front Cardiovascul Med 9:988266","journal-title":"Front Cardiovascul Med"},{"issue":"3","key":"7423_CR39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/ar3324","volume":"13","author":"G van Loo","year":"2011","unstructured":"van Loo G, Beyaert R (2011) Negative regulation of NF-\u03baB and its involvement in rheumatoid arthritis. Arthritis Res Ther 13(3):1\u201311","journal-title":"Arthritis Res Ther"},{"key":"7423_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/bs.acc.2015.03.004","volume":"70","author":"X-H Yu","year":"2015","unstructured":"Yu X-H, Zheng X-L, Tang C-K (2015) Nuclear factor-\u03baB activation as a pathological mechanism of lipid metabolism and atherosclerosis. Adv Clin Chem 70:1\u201330","journal-title":"Adv Clin Chem"},{"issue":"9","key":"7423_CR41","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1002\/art.41737","volume":"73","author":"M Rudnik","year":"2021","unstructured":"Rudnik M, Rolski F, Jordan S, Mertelj T, Stellato M, Distler O, Blyszczuk P, Kania G (2021) Regulation of monocyte adhesion and type I interferon signaling by CD52 in patients with systemic sclerosis. Arthritis & Rheumatology 73(9):1720\u20131730","journal-title":"Arthritis & Rheumatology"},{"key":"7423_CR42","doi-asserted-by":"publisher","first-page":"626820","DOI":"10.3389\/fimmu.2020.626820","volume":"11","author":"K Bhamidipati","year":"2021","unstructured":"Bhamidipati K, Silberstein JL, Chaichian Y, Baker MC, Lanz TV, Zia A, Rasheed YS, Cochran JR, Robinson WH (2021) CD52 is elevated on B cells of SLE patients and regulates B cell function. Front Immunol 11:626820","journal-title":"Front Immunol"},{"issue":"1","key":"7423_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12920-023-01531-w","volume":"16","author":"Z Zheng","year":"2023","unstructured":"Zheng Z, Yuan D, Shen C, Zhang Z, Ye J, Zhu L (2023) Identification of potential diagnostic biomarkers of atherosclerosis based on bioinformatics strategy. BMC Med Genomics 16(1):1\u201315","journal-title":"BMC Med Genomics"},{"issue":"9","key":"7423_CR44","doi-asserted-by":"publisher","first-page":"e0138123","DOI":"10.1371\/journal.pone.0138123","volume":"10","author":"RG Holgate","year":"2015","unstructured":"Holgate RG, Weldon R, Jones TD, Baker MP (2015) Characterisation of a novel anti-CD52 antibody with improved efficacy and reduced immunogenicity. PLoS ONE 10(9):e0138123","journal-title":"PLoS ONE"},{"issue":"1","key":"7423_CR45","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s12920-023-01531-w","volume":"16","author":"Z Zheng","year":"2023","unstructured":"Zheng Z, Yuan D, Shen C, Zhang Z, Ye J, Zhu L (2023) Identification of potential diagnostic biomarkers of atherosclerosis based on bioinformatics strategy. BMC Med Genomics 16(1):100","journal-title":"BMC Med Genomics"},{"issue":"1","key":"7423_CR46","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1084\/jem.20031330","volume":"199","author":"BP O'Connor","year":"2004","unstructured":"O\u2019Connor BP, Raman VS, Erickson LD, Cook WJ, Weaver LK, Ahonen C, Lin LL, Mantchev GT, Bram RJ, Noelle RJ (2004) BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 199(1):91\u201398","journal-title":"J Exp Med"},{"issue":"5","key":"7423_CR47","doi-asserted-by":"publisher","first-page":"3284","DOI":"10.1016\/j.ygeno.2020.06.010","volume":"112","author":"M Maghsoudloo","year":"2020","unstructured":"Maghsoudloo M, Jamalkandi SA, Najafi A, Masoudi-Nejad A (2020) An efficient hybrid feature selection method to identify potential biomarkers in common chronic lung inflammatory diseases. Genomics 112(5):3284\u20133293","journal-title":"Genomics"},{"issue":"11","key":"7423_CR48","doi-asserted-by":"publisher","first-page":"3554","DOI":"10.1002\/art.22929","volume":"56","author":"K Nagatani","year":"2007","unstructured":"Nagatani K, Itoh K, Nakajima K, Kuroki H, Katsuragawa Y, Mochizuki M, Aotsuka S, Mimori A (2007) Rheumatoid arthritis fibroblast-like synoviocytes express BCMA and are stimulated by APRIL. Arthritis Rheum 56(11):3554\u20133563","journal-title":"Arthritis Rheum"},{"issue":"1","key":"7423_CR49","doi-asserted-by":"publisher","first-page":"15671","DOI":"10.1038\/s41598-024-65865-w","volume":"14","author":"Y Chen","year":"2024","unstructured":"Chen Y, Ji X, Ge Y, Niu H, Zhang X, Jiang F, Wu C (2024) B-cell hub genes play a cardiovascular pathogenic role of in childhood obesity and Kawasaki disease as revealed by transcriptomics-based analyses. Sci Rep 14(1):15671","journal-title":"Sci Rep"},{"issue":"3","key":"7423_CR50","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1038\/nrd1982","volume":"5","author":"SR Dillon","year":"2006","unstructured":"Dillon SR, Gross JA, Ansell SM, Novak AJ (2006) An APRIL to remember: novel TNF ligands as therapeutic targets. Nat Rev Drug Discovery 5(3):235\u2013246","journal-title":"Nat Rev Drug Discovery"},{"issue":"6","key":"7423_CR51","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1002\/1529-0131(200106)44:6<1313::AID-ART223>3.0.CO;2-S","volume":"44","author":"GS Cheema","year":"2001","unstructured":"Cheema GS, Roschke V, Hilbert DM, Stohl W (2001) Elevated serum B lymphocyte stimulator levels in patients with systemic immune\u2013based rheumatic diseases. Arthrit Rheumat: Offl J Am College Rheumatol 44(6):1313\u20131319","journal-title":"Arthrit Rheumat: Offl J Am College Rheumatol"},{"issue":"10","key":"7423_CR52","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1160\/TH08-10-0665","volume":"102","author":"WJ Sandberg","year":"2009","unstructured":"Sandberg WJ, Otterdal K, Gullestad L, Halvorsen B, Ragnarsson A, Fr\u00f8land SS, Dam\u00e5s JK, \u00d8ie E, Aukrust P, Hansson GK (2009) The tumour necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis. Thromb Haemost 102(10):704\u2013710","journal-title":"Thromb Haemost"},{"issue":"4","key":"7423_CR53","doi-asserted-by":"publisher","first-page":"368","DOI":"10.22205\/sijbs\/2016\/v2\/i4\/103443","volume":"2","author":"M Serasanambati","year":"2016","unstructured":"Serasanambati M, Chilakapati SR (2016) Function of nuclear factor kappa B (NF-kB) in human diseases-a review. South Indian Journal of Biological Sciences 2(4):368\u2013387","journal-title":"South Indian Journal of Biological Sciences"},{"issue":"3","key":"7423_CR54","doi-asserted-by":"publisher","first-page":"e0121823","DOI":"10.1371\/journal.pone.0121823","volume":"10","author":"W-p Zhou","year":"2015","unstructured":"Zhou W-p (2015) Zhang H, Zhao Y-x, Liu G-q, Zhang J-y: RNA interference of myocyte enhancer factor 2A accelerates atherosclerosis in apolipoprotein E-deficient mice. PLoS ONE 10(3):e0121823","journal-title":"PLoS ONE"},{"issue":"21","key":"7423_CR55","doi-asserted-by":"publisher","first-page":"2345","DOI":"10.2174\/0929867324666170419150614","volume":"24","author":"X Lu","year":"2017","unstructured":"Lu X (2017) The impact of IL-17 in atherosclerosis. Curr Med Chem 24(21):2345\u20132358","journal-title":"Curr Med Chem"},{"key":"7423_CR56","doi-asserted-by":"publisher","first-page":"1013531","DOI":"10.3389\/fimmu.2022.1013531","volume":"13","author":"Z Wang","year":"2022","unstructured":"Wang Z, Xia Q, Su W, Zhang M, Gu Y, Xu J, Chen W, Jiang T (2022) The commonness in immune infiltration of rheumatoid arthritis and atherosclerosis: screening for central targets via microarray data analysis. Front Immunol 13:1013531","journal-title":"Front Immunol"},{"issue":"3","key":"7423_CR57","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1038\/s41584-021-00738-4","volume":"18","author":"L Wang","year":"2022","unstructured":"Wang L, Luqmani R, Udalova IA (2022) The role of neutrophils in rheumatic disease-associated vascular inflammation. Nat Rev Rheumatol 18(3):158\u2013170","journal-title":"Nat Rev Rheumatol"},{"issue":"3","key":"7423_CR58","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.molmed.2018.12.008","volume":"25","author":"LJ O\u2019Neil","year":"2019","unstructured":"O\u2019Neil LJ, Kaplan MJ (2019) Neutrophils in rheumatoid arthritis: breaking immune tolerance and fueling disease. Trends Mol Med 25(3):215\u2013227","journal-title":"Trends Mol Med"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-025-07423-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10067-025-07423-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-025-07423-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T14:02:55Z","timestamp":1749132175000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10067-025-07423-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,28]]},"references-count":58,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["7423"],"URL":"https:\/\/doi.org\/10.1007\/s10067-025-07423-x","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,28]]},"assertion":[{"value":"27 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 March 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}