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The NHANES protocol was approved by the Ethics Review Board of the National Center for Health Statistics. The FinnGen study project was approved by The Coordinating Ethics Committee of the Hospital District of Helsinki and Uusimaa (HUS). The other published studies included in this analysis reported ethical approval from their respective ethics committees. As our analysis did not involve any direct interaction with human subjects or access to individual-level data, no additional ethical approval or informed consent was required for this study. Our study complied with relevant ethical regulations and the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors have declared no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}]}}