{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:49:14Z","timestamp":1791586154274,"version":"4.3.4"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"DOI":"10.1007\/s10067-026-08467-3","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:00:44Z","timestamp":1791583244000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mental health\u2013related quality of life mediates the association between psychosocial factors and medication adherence in rheumatoid arthritis"],"prefix":"10.1007","author":[{"given":"Mary","family":"Gouva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parthena","family":"Alexandridou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasios","family":"Tzenalis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9698-8276","authenticated-orcid":false,"given":"Eleni N.","family":"Albani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"issue":"3","key":"8467_CR1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.509","volume":"5","author":"Y Gao","year":"2024","unstructured":"Gao Y, Zhang Y, Liu X (2024) Rheumatoid arthritis: pathogenesis and therapeutic advances. MedComm 5(3):e509. https:\/\/doi.org\/10.1002\/mco2.509","journal-title":"MedComm"},{"key":"8467_CR2","doi-asserted-by":"publisher","unstructured":"Jahid M, Khan KU, Rehan-Ul-Haq, Ahmed RS (2023) Overview of rheumatoid arthritis and scientific understanding of the disease. Mediterr J Rheumatol 34(3):284. https:\/\/doi.org\/10.31138\/mjr.20230801.oo","DOI":"10.31138\/mjr.20230801.oo"},{"issue":"5","key":"8467_CR3","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1111\/j.1365-2125.2012.04167.x","volume":"73","author":"B Vrijens","year":"2012","unstructured":"Vrijens B, De Geest S, Hughes DA, Przemyslaw K, Demonceau J, Ruppar T, Dobbels F, Fargher E, Morrison V, Lewek P, Matyjaszczyk M, Mshelia C, Clyne W, Aronson JK, Urquhart J, ABC Project Team (2012) A new taxonomy for describing and defining adherence to medications. Br J Clin Pharmacol 73(5):691\u2013705. https:\/\/doi.org\/10.1111\/j.1365-2125.2012.04167.x","journal-title":"Br J Clin Pharmacol"},{"issue":"5","key":"8467_CR4","doi-asserted-by":"publisher","first-page":"358","DOI":"10.5114\/reum\/208307","volume":"63","author":"GH Islam","year":"2025","unstructured":"Islam GH, Rasool MT (2025) Adherence to treatment and associated factors in rheumatoid arthritis in Kurdish patients: a cross-sectional study. Reumatologia 63(5):358\u2013363. https:\/\/doi.org\/10.5114\/reum\/208307","journal-title":"Reumatologia"},{"issue":"9","key":"8467_CR5","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1097\/00005650-200209000-00009","volume":"40","author":"MR DiMatteo","year":"2002","unstructured":"DiMatteo MR, Giordani PJ, Lepper HS, Croghan TW (2002) Patient adherence and medical treatment outcomes: a meta-analysis. Med Care 40(9):794\u2013811. https:\/\/doi.org\/10.1097\/00005650-200209000-00009","journal-title":"Med Care"},{"key":"8467_CR6","doi-asserted-by":"publisher","first-page":"573","DOI":"10.2147\/CEOR.S175877","volume":"10","author":"J Shafrin","year":"2018","unstructured":"Shafrin J, Bognar K, Everson K, Brauer M, Lakdawalla DN, Forma FM (2018) Does knowledge of patient non-compliance change prescribing behavior in the real world? A claims-based analysis of patients with serious mental illness. Clin Outcomes Res 10:573\u2013585. https:\/\/doi.org\/10.2147\/CEOR.S175877","journal-title":"Clin Outcomes Res"},{"issue":"10416","key":"8467_CR7","doi-asserted-by":"publisher","first-page":"2019","DOI":"10.1016\/S0140-6736(23)01525-8","volume":"402","author":"A Di Matteo","year":"2023","unstructured":"Di Matteo A, Bathon JM, Emery P (2023) Rheumatoid arthritis. Lancet 402(10416):2019\u20132033. https:\/\/doi.org\/10.1016\/S0140-6736(23)01525-8","journal-title":"Lancet"},{"issue":"4","key":"8467_CR8","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1097\/NOR.0b013e3181e5c2c9","volume":"29","author":"E Salt","year":"2010","unstructured":"Salt E, Frazier SK (2010) Adherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a narrative review of the literature. Orthop Nurs 29(4):260\u2013275. https:\/\/doi.org\/10.1097\/NOR.0b013e3181e5c2c9","journal-title":"Orthop Nurs"},{"key":"8467_CR9","doi-asserted-by":"publisher","first-page":"2565","DOI":"10.2147\/PPA.S529952","volume":"19","author":"L Liang","year":"2025","unstructured":"Liang L, Zhang X, Pan Y, Huang L, Jia L, Xu P, Li K (2025) Exploring the factors related to medication adherence in patients with rheumatoid arthritis based on social cognitive theory: a path analysis. Patient Prefer Adherence 19:2565\u20132575. https:\/\/doi.org\/10.2147\/PPA.S529952","journal-title":"Patient Prefer Adherence"},{"issue":"9","key":"8467_CR10","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1177\/1359105316646440","volume":"23","author":"S Brandstetter","year":"2018","unstructured":"Brandstetter S, Riedelbeck G, Steinmann M, Loss J, Ehrenstein B, Apfelbacher C (2018) Depression moderates the associations between beliefs about medicines and medication adherence in patients with rheumatoid arthritis: cross-sectional study. J Health Psychol 23(9):1185\u20131195. https:\/\/doi.org\/10.1177\/1359105316646440","journal-title":"J Health Psychol"},{"issue":"10","key":"8467_CR11","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1007\/s11606-011-1704-y","volume":"26","author":"JL Grenard","year":"2011","unstructured":"Grenard JL, Munjas BA, Adams JL, Suttorp M, Maglione M, McGlynn EA, Gellad WF (2011) Depression and medication adherence in the treatment of chronic diseases in the United States: a meta-analysis. J Gen Intern Med 26(10):1175\u20131182. https:\/\/doi.org\/10.1007\/s11606-011-1704-y","journal-title":"J Gen Intern Med"},{"issue":"1","key":"8467_CR12","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2015-000171","volume":"2","author":"HF Hope","year":"2016","unstructured":"Hope HF, Bluett J, Barton A, Hyrich KL, Cordingley L, Verstappen SMM (2016) Psychological factors predict adherence to methotrexate in rheumatoid arthritis; findings from a systematic review of rates, predictors and associations with patient-reported and clinical outcomes. RMD Open 2(1):e000171. https:\/\/doi.org\/10.1136\/rmdopen-2015-000171","journal-title":"RMD Open"},{"key":"8467_CR13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-33664-6","author":"M Davoodifard","year":"2025","unstructured":"Davoodifard M, Vagharseyyedin SA, Saremi Z (2025) The impact of peer support groups on the psychological well-being of patients with rheumatoid arthritis: a randomized controlled trial. Sci Rep. https:\/\/doi.org\/10.1038\/s41598-025-33664-6","journal-title":"Sci Rep"},{"issue":"1","key":"8467_CR14","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1037\/0022-006X.60.1.119","volume":"60","author":"G Affleck","year":"1992","unstructured":"Affleck G, Tennen H, Urrows S, Higgins P (1992) Neuroticism and the pain-mood relation in rheumatoid arthritis: insights from a prospective daily study. J Consult Clin Psychol 60(1):119\u2013126. https:\/\/doi.org\/10.1037\/0022-006X.60.1.119","journal-title":"J Consult Clin Psychol"},{"issue":"11","key":"8467_CR15","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1136\/ard.61.11.1000","volume":"61","author":"L-O Persson","year":"2002","unstructured":"Persson L-O, Sahlberg D (2002) The influence of negative illness cognitions and neuroticism on subjective symptoms and mood in rheumatoid arthritis. Ann Rheum Dis 61(11):1000\u20131006. https:\/\/doi.org\/10.1136\/ard.61.11.1000","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"8467_CR16","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-22021-6","volume":"12","author":"I Stanciu","year":"2022","unstructured":"Stanciu I, Anderson J, Siebert S, Mackay D, Lyall DM (2022) Associations of rheumatoid arthritis and rheumatoid factor with mental health, sleep and cognition characteristics in the UK Biobank. Sci Rep 12(1):19844. https:\/\/doi.org\/10.1038\/s41598-022-22021-6","journal-title":"Sci Rep"},{"issue":"5757","key":"8467_CR17","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1136\/bmj.2.5757.297","volume":"2","author":"DJ Ward","year":"1971","unstructured":"Ward DJ (1971) Rheumatoid arthritis and personality: a controlled study. BMJ 2(5757):297\u2013299. https:\/\/doi.org\/10.1136\/bmj.2.5757.297","journal-title":"BMJ"},{"issue":"11","key":"8467_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare12111087","volume":"12","author":"C-M Cojocaru","year":"2024","unstructured":"Cojocaru C-M, Popa CO, Schenk A, Marian \u0218, Marchean H, Suciu BA, Szasz S, Popoviciu H, Mure\u0219an S (2024) Personality and pain outcomes in rheumatic disease: the mediating role of psychological flexibility. Healthcare (Basel) 12(11):1087. https:\/\/doi.org\/10.3390\/healthcare12111087","journal-title":"Healthcare (Basel)"},{"issue":"3","key":"8467_CR19","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1097\/HNP.0000000000000645","volume":"38","author":"B Babada\u011f Sava\u015f","year":"2024","unstructured":"Babada\u011f Sava\u015f B, Orlu N, Balc\u0131 Alparslan G, \u00c7olak E, Korkmaz C (2024) Effect of humor on pain and anxiety in patients with rheumatoid arthritis: a prospective, randomized controlled study. Holist Nurs Pract 38(3):130\u2013137. https:\/\/doi.org\/10.1097\/HNP.0000000000000645","journal-title":"Holist Nurs Pract"},{"key":"8467_CR20","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.55201","author":"E Bartzou","year":"2024","unstructured":"Bartzou E, Tsiloni E, Mantzoukas S, Dragioti E, Gouva M (2024) Humor and quality of life in adults with chronic diseases: a systematic review. Cureus. https:\/\/doi.org\/10.7759\/cureus.55201","journal-title":"Cureus"},{"issue":"1","key":"8467_CR21","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1177\/089801019301100110","volume":"11","author":"CM Leise","year":"1993","unstructured":"Leise CM (1993) The correlation between humor and the chronic pain of arthritis. J Holist Nurs 11(1):82\u201395. https:\/\/doi.org\/10.1177\/089801019301100110","journal-title":"J Holist Nurs"},{"issue":"4","key":"8467_CR22","doi-asserted-by":"publisher","first-page":"358","DOI":"10.5964\/ejop.10013","volume":"19","author":"A Dionigi","year":"2023","unstructured":"Dionigi A, Duradoni M, Vagnoli L (2023) Understanding the association between humor and emotional distress: the role of light and dark humor in predicting depression, anxiety, and stress. Eur J Psychol 19(4):358\u2013370. https:\/\/doi.org\/10.5964\/ejop.10013","journal-title":"Eur J Psychol"},{"key":"8467_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2019.109641","volume":"154","author":"HL Fritz","year":"2020","unstructured":"Fritz HL (2020) Why are humor styles associated with well-being, and does social competence matter? Examining relations to psychological and physical well-being, reappraisal, and social support. Pers Individ Dif 154:109641. https:\/\/doi.org\/10.1016\/j.paid.2019.109641","journal-title":"Pers Individ Dif"},{"issue":"1","key":"8467_CR24","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/S0092-6566(02)00534-2","volume":"37","author":"RA Martin","year":"2003","unstructured":"Martin RA, Puhlik-Doris P, Larsen G, Gray J, Weir K (2003) Individual differences in uses of humor and their relation to psychological well-being: development of the Humor Styles Questionnaire. J Res Pers 37(1):48\u201375. https:\/\/doi.org\/10.1016\/S0092-6566(02)00534-2","journal-title":"J Res Pers"},{"key":"8467_CR25","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.106692","author":"P Alexandridou","year":"2026","unstructured":"Alexandridou P, Gouva M, Zagorianakou N, Konstanti Z, Tzenalis A, Albani EN (2026) Personality and humor profiles in rheumatoid arthritis: a latent profile analysis of quality of life and medication adherence. Cureus. https:\/\/doi.org\/10.7759\/cureus.106692","journal-title":"Cureus"},{"key":"8467_CR26","doi-asserted-by":"crossref","unstructured":"Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473\u2013483","DOI":"10.1097\/00005650-199206000-00002"},{"key":"8467_CR27","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1007\/s11136-004-6014-y","volume":"14","author":"E Pappa","year":"2005","unstructured":"Pappa E, Kontodimopoulos N, Niakas D (2005) Validating and norming of the Greek SF-36 health survey. Qual Life Res 14:1433\u20131438. https:\/\/doi.org\/10.1007\/s11136-004-6014-y","journal-title":"Qual Life Res"},{"issue":"1","key":"8467_CR28","first-page":"59","volume":"15","author":"M Krousel-Wood","year":"2009","unstructured":"Krousel-Wood M, Islam T, Webber LS, Re RN, Morisky DE, Muntner P (2009) New medication adherence scale versus pharmacy fill rates in seniors with hypertension. Am J Manag Care 15(1):59\u201366","journal-title":"Am J Manag Care"},{"key":"8467_CR29","doi-asserted-by":"publisher","first-page":"158","DOI":"10.4236\/ojn.2016.63017","volume":"6","author":"S Plakas","year":"2016","unstructured":"Plakas S, Mastrogiannis D, Mantzorou M et al (2016) Validation of the 8-item morisky medication adherence scale in chronically Ill ambulatory patients in Rural Greece. Open J Nurs 6:158\u2013169. https:\/\/doi.org\/10.4236\/ojn.2016.63017","journal-title":"Open J Nurs"},{"key":"8467_CR30","volume-title":"Manual of the Eysenck Personality Questionnaire (Junior and Adult)","author":"HJ Eysenck","year":"1975","unstructured":"Eysenck HJ, Eysenck SBG (1975) Manual of the Eysenck Personality Questionnaire (Junior and Adult). Hodder & Stoughton, London"},{"key":"8467_CR31","first-page":"41","volume":"23","author":"EX Demetriou","year":"1986","unstructured":"Demetriou EX (1986) The eysenck personality questionnaire: standardization to the Greek population, adult and junior. Engefalos 23:41\u201354","journal-title":"Engefalos"},{"key":"8467_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2019.109676","volume":"154","author":"CY Plessen","year":"2020","unstructured":"Plessen CY, Franken FR, Ster C, Schmid RR, Wolfmayr C, Mayer A-M, Sobisch M, Kathofer M, Rattner K, Kotlyar E, Maierwieser RJ, Tran US (2020) Humor styles and personality: a systematic review and meta-analysis on the relations between humor styles and the Big Five personality traits. Pers Individ Dif 154:109676. https:\/\/doi.org\/10.1016\/j.paid.2019.109676","journal-title":"Pers Individ Dif"},{"issue":"2","key":"8467_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20021008","volume":"20","author":"A Di Fabio","year":"2023","unstructured":"Di Fabio A, Gori A, Svicher A (2023) Relationships between humor styles and the big five personality traits in workers: a network analysis. Int J Environ Res Public Health 20(2):1008. https:\/\/doi.org\/10.3390\/ijerph20021008","journal-title":"Int J Environ Res Public Health"},{"key":"8467_CR34","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.02213","volume":"11","author":"F Jiang","year":"2020","unstructured":"Jiang F, Lu S, Jiang T, Jia H (2020) Does the relation between humor styles and subjective well-being vary across culture and age? A meta-analysis. Front Psychol 11:2213. https:\/\/doi.org\/10.3389\/fpsyg.2020.02213","journal-title":"Front Psychol"},{"issue":"2","key":"8467_CR35","doi-asserted-by":"publisher","first-page":"179","DOI":"10.3390\/bs13020179","volume":"13","author":"L Simione","year":"2023","unstructured":"Simione L, Gnagnarella C (2023) Humor coping reduces the positive relationship between avoidance coping strategies and perceived stress: a moderation analysis. Behav Sci 13(2):179. https:\/\/doi.org\/10.3390\/bs13020179","journal-title":"Behav Sci"},{"key":"8467_CR36","doi-asserted-by":"publisher","unstructured":"Frewen PA, Brinker J, Martin RA, Dozois DJA (2008) Humor styles and personality-vulnerability to depression. Hum Int J Hum Res 21(2). https:\/\/doi.org\/10.1515\/HUMOR.2008.009","DOI":"10.1515\/HUMOR.2008.009"},{"issue":"4","key":"8467_CR37","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.hrtlng.2015.03.006","volume":"44","author":"J-R Wu","year":"2015","unstructured":"Wu J-R, Song EK, Moser DK (2015) Type D personality, self-efficacy, and medication adherence in patients with heart failure\u2014a mediation analysis. Heart Lung 44(4):276\u2013281. https:\/\/doi.org\/10.1016\/j.hrtlng.2015.03.006","journal-title":"Heart Lung"},{"key":"8467_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2022.154273","volume":"241","author":"V Ricci","year":"2023","unstructured":"Ricci V, Ricci C, Tamborrini G, Chang KV, Mezian K, Zunica F, Na\u0148ka O, Kara M, \u00d6z\u00e7akar L (2023) From histology to sonography in synovitis: EURO-MUSCULUS\/USPRM approach. Pathol Res Pract 241:154273. https:\/\/doi.org\/10.1016\/j.prp.2022.154273","journal-title":"Pathol Res Pract"},{"issue":"9","key":"8467_CR39","doi-asserted-by":"publisher","first-page":"e124","DOI":"10.1097\/PHM.0000000000002929","volume":"105","author":"HB Abac\u0131o\u011flu","year":"2026","unstructured":"Abac\u0131o\u011flu HB, \u00c7etin A (2026) Advanced ultrasonographic insights into neglected\/occult Achilles tendon rupture in rheumatoid arthritis. Am J Phys Med Rehabil 105(9):e124. https:\/\/doi.org\/10.1097\/PHM.0000000000002929","journal-title":"Am J Phys Med Rehabil"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-026-08467-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10067-026-08467-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-026-08467-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:00:45Z","timestamp":1791583245000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10067-026-08467-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,9]]},"references-count":39,"alternative-id":["8467"],"URL":"https:\/\/doi.org\/10.1007\/s10067-026-08467-3","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,9]]},"assertion":[{"value":"9 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"None.","order":1,"name":"Ethics","label":"Disclosures","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}}]}}