{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:44:52Z","timestamp":1782996292076,"version":"3.54.5"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2015,5,8]],"date-time":"2015-05-08T00:00:00Z","timestamp":1431043200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1007\/s10072-015-2235-9","type":"journal-article","created":{"date-parts":[[2015,5,7]],"date-time":"2015-05-07T11:41:53Z","timestamp":1430998913000},"page":"1135-1140","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The HLA-B*4601-DRB1*0901 haplotype is positively correlated with juvenile ocular myasthenia gravis in a southern Chinese Han population"],"prefix":"10.1007","volume":"36","author":[{"given":"Hui-yu","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-xuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-bin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,5,8]]},"reference":[{"issue":"5","key":"2235_CR1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/ene.12359","volume":"21","author":"E Kerty","year":"2014","unstructured":"Kerty E, Elsais A, Argov Z et al (2014) EFNS\/ENS guidelines for the treatment of ocular myasthenia. Eur J Neurol 21(5):687\u2013693","journal-title":"Eur J Neurol"},{"key":"2235_CR2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jaut.2014.01.003","volume":"48\u201349","author":"S Berrih-Aknin","year":"2014","unstructured":"Berrih-Aknin S, Frenkian-Cuvelier M, Eymard B (2014) Diagnostic and clinical classification of autoimmune myasthenia gravis. J Autoimmun 48\u201349:143\u2013148","journal-title":"J Autoimmun"},{"issue":"3","key":"2235_CR3","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1586\/14737175.9.3.351","volume":"9","author":"NE Gilhus","year":"2009","unstructured":"Gilhus NE (2009) Autoimmune myasthenia gravis. Expert Rev Neurother 9(3):351\u2013358","journal-title":"Expert Rev Neurother"},{"issue":"3","key":"2235_CR4","first-page":"289","volume":"7","author":"F Li","year":"2001","unstructured":"Li F, Szobor A, Croxen R et al (2001) Dominantly inherited familial myasthenia gravis as a separate genetic entity without involvement of defined candidate gene loci. Int J Mol Med 7(3):289\u2013294","journal-title":"Int J Mol Med"},{"issue":"11","key":"2235_CR5","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.2169\/internalmedicine.47.0838","volume":"47","author":"BW Lee","year":"2008","unstructured":"Lee BW, Ihm SH, Shin HS et al (2008) Malignant thymoma associated with myasthenia gravis, Graves\u2019 disease, and SIADH. Inter Med 47(11):1009\u20131012","journal-title":"Inter Med"},{"issue":"12","key":"2235_CR6","doi-asserted-by":"crossref","first-page":"947","DOI":"10.5692\/clinicalneurol.54.947","volume":"54","author":"H Murai","year":"2014","unstructured":"Murai H (2014) Myasthenia gravis: past, present and future. Rinsho Shinkeigaku 54(12):947\u2013949","journal-title":"Rinsho Shinkeigaku"},{"issue":"4","key":"2235_CR7","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s10072-011-0818-7","volume":"33","author":"HY Feng","year":"2012","unstructured":"Feng HY, Liu WB, Luo CM et al (2012) A retrospective review of 15 patients with familial myasthenia gravis over a period of 25 years. Neurol Sci 33(4):771\u2013777","journal-title":"Neurol Sci"},{"issue":"2","key":"2235_CR8","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1055\/s-0029-1224873","volume":"27","author":"M Saint-Faust","year":"2010","unstructured":"Saint-Faust M, Perelman S, Dupont D et al (2010) Transient neonatal myasthenia gravis revealing a myasthenia gravis and a systemic lupus erythematosus in the mother: case report and review of the literature. Am J Perinatol 27(2):107\u2013110","journal-title":"Am J Perinatol"},{"issue":"1","key":"2235_CR9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1212\/WNL.38.1.38","volume":"38","author":"L Kerzin-Storrar","year":"1988","unstructured":"Kerzin-Storrar L, Metcalfe RA, Dyer PA et al (1988) Genetic factors in myasthenia gravis: a family study. Neurology 38(1):38\u201342","journal-title":"Neurology"},{"issue":"9","key":"2235_CR10","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1136\/jnnp.51.9.1228","volume":"51","author":"C Provenzano","year":"1988","unstructured":"Provenzano C, Arancio O, Evoli A et al (1988) Familial autoimmune myasthenia gravis with different pathogenetic antibodies. J Neurol Neurosurg Psychiatry 51(9):1228\u20131230","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"6","key":"2235_CR11","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s10072-012-1157-z","volume":"34","author":"X Huang","year":"2013","unstructured":"Huang X, Liu WB, Men LN et al (2013) Clinical features of myasthenia gravis in southern China: retrospective review of 2154 cases over 22 years. Neurol Sci 34(6):911\u2013917","journal-title":"Neurol Sci"},{"issue":"1","key":"2235_CR12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1744-313X.2010.00979.x","volume":"38","author":"PR Deitiker","year":"2011","unstructured":"Deitiker PR, Oshima M, Smith RG et al (2011) Association with HLA DQ of early onset myasthenia gravis in Southeast Texas region of the United States. Int J Immunogenet 38(1):55\u201362","journal-title":"Int J Immunogenet"},{"issue":"52","key":"2235_CR13","doi-asserted-by":"crossref","first-page":"40800","DOI":"10.1074\/jbc.M110.148155","volume":"285","author":"M Lith van","year":"2010","unstructured":"van Lith M, McEwen-Smith RM, Benham AM (2010) HLA-DP, HLA-DQ, and HLA-DR have different requirements for invariant chain and HLA-DM. J Biol Chem 285(52):40800\u201340808","journal-title":"J Biol Chem"},{"issue":"1\u20132","key":"2235_CR14","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jneuroim.2010.04.017","volume":"225","author":"K Iwasa","year":"2010","unstructured":"Iwasa K, Kato-Motozaki Y, Furukawa Y et al (2010) Up-regulation of MHC class I and class II in the skeletal muscles of myasthenia gravis. J Neuroimmunol 225(1\u20132):171\u2013174","journal-title":"J Neuroimmunol"},{"issue":"11","key":"2235_CR15","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1016\/j.jocn.2011.05.002","volume":"18","author":"YC Xie","year":"2011","unstructured":"Xie YC, Qu Y, Sun L et al (2011) Association between HLA-DRB1 and myasthenia gravis in a northern Han Chinese population. J Clin Neurosci 18(11):1524\u20131527","journal-title":"J Clin Neurosci"},{"issue":"1","key":"2235_CR16","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/ene.12525","volume":"22","author":"AV Nikolic","year":"2015","unstructured":"Nikolic AV, Andric ZP, Simonovic RB et al (2015) High frequency of DQB1*05 and absolute absence of DRB1*13 in muscle-specific tyrosine kinase positive myasthenia gravis. Eur J Neurol 22(1):59\u201363","journal-title":"Eur J Neurol"},{"issue":"2","key":"2235_CR17","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1212\/01.wnl.0000339103.08830.86","volume":"72","author":"E Bartoccioni","year":"2009","unstructured":"Bartoccioni E, Scuderi F, Augugliaro A et al (2009) HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5. Neurology 72(2):195\u2013197","journal-title":"Neurology"},{"issue":"4","key":"2235_CR18","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1080\/08916930600738581","volume":"39","author":"PR Deitiker","year":"2006","unstructured":"Deitiker PR, Oshima M, Smith RG et al (2006) Subtle differences in HLA DQ haplotype-associated presentation of AChR alpha-chain peptides may suffice to mediate myasthenia gravis. Autoimmunity 39(4):277\u2013288","journal-title":"Autoimmunity"},{"issue":"12","key":"2235_CR19","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1016\/j.humimm.2013.08.271","volume":"74","author":"M Alahgholi-Hajibehzad","year":"2013","unstructured":"Alahgholi-Hajibehzad M, Yilmaz V, G\u00fclsen-Parman Y et al (2013) Association of HLA-DRB1*14, -DRB1*16 and -DQB1*05 with MuSK-myasthenia gravis in patients from Turkey. Hum Immunol 74(12):1633\u20131635","journal-title":"Hum Immunol"},{"issue":"11","key":"2235_CR20","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1212\/01.wnl.0000218159.79769.5c","volume":"66","author":"EH Niks","year":"2006","unstructured":"Niks EH, Kuks JB, Roep BO et al (2006) Strong association of MuSK antibody-positive myasthenia gravis and HLA-DR14-DQ5. Neurology 66(11):1772\u20131774","journal-title":"Neurology"},{"key":"2235_CR21","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jaut.2013.12.007","volume":"52","author":"M Marino","year":"2014","unstructured":"Marino M, Maiuri MT, Di Sante G et al (2014) T cell repertoire in DQ5-positive MuSK-positive myasthenia gravis patients. J Autoimmun 52:113\u2013121","journal-title":"J Autoimmun"},{"issue":"2","key":"2235_CR22","first-page":"99","volume":"6","author":"GA Yousefipour","year":"2009","unstructured":"Yousefipour GA, Salami Z, Farjadian S (2009) Association of HLA-DQA1*0101\/2 and DQB1*0502 with myasthenia gravis in southern Iranian patients. Iran J Immunol 6(2):99\u2013102","journal-title":"Iran J Immunol"},{"issue":"1","key":"2235_CR23","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1212\/WNL.55.1.16","volume":"55","author":"A Jaretzki 3rd","year":"2000","unstructured":"Jaretzki A 3rd, Barohn RB, Ernstoff RM et al (2000) Myasthenia gravis. Recommendations for clinical research standards. Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America. Neurology 55(1):16\u201323","journal-title":"Neurology"},{"issue":"12","key":"2235_CR24","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.neurol.2010.08.004","volume":"166","author":"T Stojkovic","year":"2010","unstructured":"Stojkovic T, Behin A (2010) Ocular myasthenia: diagnosis and treatment. Rev Neurol 166(12):987\u2013997","journal-title":"Rev Neurol"},{"issue":"4","key":"2235_CR25","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/ene.12057","volume":"20","author":"H Zach","year":"2013","unstructured":"Zach H, Cetin H, Hilger E et al (2013) The effect of early prednisolone treatment on generalization. Eur J Neurol 20(4):708\u2013713","journal-title":"Eur J Neurol"},{"issue":"1","key":"2235_CR26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/11584740-000000000-00000","volume":"3","author":"C Angelini","year":"2011","unstructured":"Angelini C (2011) Diagnosis and management of autoimmune myasthenia gravis. Clin Drug Investig 3(1):1\u201314","journal-title":"Clin Drug Investig"},{"issue":"1\u20132","key":"2235_CR27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jns.2012.10.028","volume":"325","author":"MA Hellmann","year":"2013","unstructured":"Hellmann MA, Mosberg-Galili R, Steiner I (2013) Myasthenia gravis in the elderly. J Neurol Sci 325(1\u20132):1\u20135","journal-title":"J Neurol Sci"},{"key":"2235_CR28","first-page":"1222","volume":"31","author":"M Segawa","year":"1973","unstructured":"Segawa M (1973) Myasthenia gravis\u2014latent general type. Naika 31:1222\u20131226","journal-title":"Naika"},{"issue":"2","key":"2235_CR29","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.clim.2003.10.004","volume":"110","author":"N Shinomiya","year":"2004","unstructured":"Shinomiya N, Nomura Y, Segawab M (2004) A variant of childhood-onset myasthenia gravis: HLA typing and clinical characteristics in Japan. Clin Immunol 110(2):154\u2013158","journal-title":"Clin Immunol"},{"issue":"3","key":"2235_CR30","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.athoracsur.2012.11.074","volume":"95","author":"C Cheng","year":"2013","unstructured":"Cheng C, Liu Z, Xu F et al (2013) Clinical outcome of juvenile myasthenia gravis after extended transsternal thymectomy in a Chinese cohort. Ann Thorac Surg 95(3):1035\u20131041","journal-title":"Ann Thorac Surg"},{"issue":"12","key":"2235_CR31","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1007\/s10072-013-1443-4","volume":"34","author":"H Wang","year":"2013","unstructured":"Wang H, Su Z, Luo C et al (2013) The effect of steroid treatment and thymectomy on bone age and height development in juvenile myasthenia gravis. Neurol Sci 34(12):2173\u20132180","journal-title":"Neurol Sci"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-015-2235-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10072-015-2235-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-015-2235-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T05:19:10Z","timestamp":1559107150000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10072-015-2235-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,8]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["2235"],"URL":"https:\/\/doi.org\/10.1007\/s10072-015-2235-9","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,8]]}}}