{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T14:19:06Z","timestamp":1763389146644},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T00:00:00Z","timestamp":1527465600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1007\/s10072-018-3429-8","type":"journal-article","created":{"date-parts":[[2018,6,15]],"date-time":"2018-06-15T07:12:58Z","timestamp":1529046778000},"page":"33-37","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Migraine and cerebrovascular disease: still a dangerous connection?"],"prefix":"10.1007","volume":"39","author":[{"given":"Elio Clemente","family":"Agostoni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Longoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,5,28]]},"reference":[{"key":"3429_CR1","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/S0140-6736(04)15440-8","volume":"363","author":"SD Silberstein","year":"2004","unstructured":"Silberstein SD (2004) Migraine. Lancet 363:381\u2013391","journal-title":"Lancet"},{"key":"3429_CR2","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1007\/s11910-004-0022-8","volume":"4","author":"ME Bigal","year":"2004","unstructured":"Bigal ME, Lipton RB, Stewart WF (2004) The epidemiology and impact of migraine. Curr Neurol Neurosci Rep 4:98\u2013104. \n                    https:\/\/doi.org\/10.1007\/s11910-004-0022-8","journal-title":"Curr Neurol Neurosci Rep"},{"key":"3429_CR3","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1016\/0895-4356(91)90147-2","volume":"44","author":"BK Rasmussen","year":"1991","unstructured":"Rasmussen BK, Jensen R, Schroll et al (1991) Epidemiology of headache in a general population\u2014a prevalence study. J Clin Epidemiol 44:1147\u20131157. \n                    https:\/\/doi.org\/10.1016\/0895-4356(91)90147-2","journal-title":"J Clin Epidemiol"},{"key":"3429_CR4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i2610","volume":"353","author":"T Kurth","year":"2016","unstructured":"Kurth T, Winter AC, Eliassen AH, Dushkes R, Mukamal KJ, Rimm EB, Willett WC, Manson JAE, Rexrode KM (2016) Migraine and risk of cardiovascular disease in women: prospective cohort study. BMJ 353:i2610. \n                    https:\/\/doi.org\/10.1136\/bmj.i2610","journal-title":"BMJ"},{"key":"3429_CR5","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1111\/ene.12701","volume":"22","author":"S Sacco","year":"2015","unstructured":"Sacco S, Ornello R, Ripa P, Tiseo C, Degan D, Pistoia F, Carolei A (2015) Migraine and risk of ischaemic heart disease: a systematic review and meta-analysis of observational studies. Eur J Neurol 22:1001\u20131011. \n                    https:\/\/doi.org\/10.1111\/ene.12701","journal-title":"Eur J Neurol"},{"key":"3429_CR6","doi-asserted-by":"publisher","first-page":"b3914","DOI":"10.1136\/bmj.b3914","volume":"339","author":"M Sch\u00fcrks","year":"2009","unstructured":"Sch\u00fcrks M, Rist PM, Bigal et al (2009) Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ 339:b3914. \n                    https:\/\/doi.org\/10.1136\/bmj.b3914","journal-title":"BMJ"},{"key":"3429_CR7","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1111\/j.1468-2982.2009.01937.x","volume":"29","author":"GE Tietjen","year":"2009","unstructured":"Tietjen GE (2009) Migraine as a systemic vasculopathy. Cephalalgia 29:987\u2013996. \n                    https:\/\/doi.org\/10.1111\/j.1468-2982.2009.01937.x","journal-title":"Cephalalgia"},{"key":"3429_CR8","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1212\/01.wnl.0000294329.93565.94","volume":"70","author":"ST Lee","year":"2008","unstructured":"Lee ST, Chu K, Jung KH et al (2008) Decreased number and function of endothelial progenitor cells in patients with migraine. Neurology 70:1510\u20131517. \n                    https:\/\/doi.org\/10.1212\/01.wnl.0000294329.93565.94","journal-title":"Neurology"},{"key":"3429_CR9","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1111\/j.15264610.2012.02143.x","volume":"52","author":"JT Jesurum","year":"2012","unstructured":"Jesurum JT, Fuller CJ, Murinova N, Truva CM, Lucas SM (2012) Aspirin\u2019s effect on platelet inhibition in migraineurs. Headache 52:1207\u20131218. \n                    https:\/\/doi.org\/10.1111\/j.15264610.2012.02143.x","journal-title":"Headache"},{"key":"3429_CR10","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1212\/01.wnl.0000260964.28393.ed","volume":"68","author":"FH Vanmolkot","year":"2007","unstructured":"Vanmolkot FH, Van Bortel LM, de Hoon JN (2007) Altered arterial function in migraine of recent onset. Neurology 68:1563\u20131570. \n                    https:\/\/doi.org\/10.1212\/01.wnl.0000260964.28393.ed","journal-title":"Neurology"},{"issue":"Suppl 2","key":"3429_CR11","doi-asserted-by":"publisher","first-page":"S107","DOI":"10.1007\/s10072-006-0582-2","volume":"27","author":"M Longoni","year":"2006","unstructured":"Longoni M, Ferrarese C (2006) Inflammation and excitotoxicity: role in migraine pathogenesis. Neurol Sci 27(Suppl 2):S107\u2013S110","journal-title":"Neurol Sci"},{"key":"3429_CR12","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1136\/bmj.310.6983.830","volume":"310","author":"C Tzourio","year":"1995","unstructured":"Tzourio C, Tehindrazanarivelo A, Iglesias S, Alperovitch A, Chedru F, d'Anglejan-Chatillon J, Bousser MG (1995) Case-control study of migraine and risk of ischaemic stroke in young women. BMJ 310:830\u2013833","journal-title":"BMJ"},{"key":"3429_CR13","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1016\/S0140-6736(96)90669-8","volume":"347","author":"A Carolei","year":"1996","unstructured":"Carolei A, Marini C, De Matteis G (1996) History of migraine and risk of cerebral ischaemia in young adults. Lancet 347:1503\u20131506","journal-title":"Lancet"},{"key":"3429_CR14","doi-asserted-by":"publisher","first-page":"b3914","DOI":"10.1136\/bmj.b3914","volume":"339","author":"M Sch\u00fcrks","year":"2009","unstructured":"Sch\u00fcrks M, Rist PM, Bigal ME et al (2009) Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ 339:b3914","journal-title":"BMJ"},{"key":"3429_CR15","doi-asserted-by":"publisher","first-page":"3032","DOI":"10.1161\/STROKEAHA.113.002465","volume":"44","author":"S Sacco","year":"2013","unstructured":"Sacco S, Ornello R, Ripa P, Pistoia F, Carolei A (2013) Migraine and hemorrhagic stroke: a meta-analysis. Stroke 44:3032\u20133038","journal-title":"Stroke"},{"key":"3429_CR16","doi-asserted-by":"publisher","first-page":"i6635","DOI":"10.1136\/bmj.i6635","volume":"356","author":"FP Timm","year":"2017","unstructured":"Timm FP, Houle TT, Grabitz SD et al (2017) Migraine and risk of perioperative ischemic stroke and hospital readmission: hospital based registry study. BMJ 356:i6635","journal-title":"BMJ"},{"key":"3429_CR17","doi-asserted-by":"publisher","unstructured":"Adelborg K, Komj\u00e1thin\u00e9 Sz\u00e9pligeti S, Holland-Bill L et al (2018) Migraine and risk of cardiovascular diseases: Danish population based matched cohort study. BMJ 360:k96. \n                    https:\/\/doi.org\/10.1136\/bmj.k96","DOI":"10.1136\/bmj.k96"},{"issue":"3","key":"3429_CR18","doi-asserted-by":"publisher","first-page":"e020498","DOI":"10.1136\/bmjopen-2017-020498","volume":"8","author":"A Mahmoud","year":"2018","unstructured":"Mahmoud A, Mentias A, Elgendy A (2018) Migraine and the risk of cardiovascular and cerebrovascular events: a meta-analysis of 16 cohort studies including 1 152 407 subjects. BMJ Open 8(3):e020498 Published online 2018 Mar 27","journal-title":"BMJ Open"},{"key":"3429_CR19","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.1212\/WNL.0b013e3181a71220","volume":"72","author":"ME Bigal","year":"2009","unstructured":"Bigal ME, Kurth T, Hu H, Santanello N, Lipton RB (2009) Migraine and cardiovascular disease: possible mechanisms of interaction. Neurology 72:1864\u20131871","journal-title":"Neurology"},{"key":"3429_CR20","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1212\/01.wnl.0000179800.73706.20","volume":"65","author":"M Schwerzmann","year":"2005","unstructured":"Schwerzmann M, Nedeltchev K, Lagger F, Mattle HP, Windecker S, Meier B, Seiler C (2005) Prevalence and size of directly detected patent foramen ovale in migraine with aura. Neurology 65:1415\u20131418","journal-title":"Neurology"},{"key":"3429_CR21","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d3450","volume":"343","author":"M Schmidt","year":"2011","unstructured":"Schmidt M, Christiansen CF, Mehnert F, Rothman KJ, Sorensen HT (2011) Non-steroidal anti-inflammatory drug use and risk of atrial fibrillation or flutter: population based case-control study. BMJ 343:d3450","journal-title":"BMJ"},{"key":"3429_CR22","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1177\/0333102411427599","volume":"31","author":"P Mart\u00ednez-S\u00e1nchez","year":"2011","unstructured":"Mart\u00ednez-S\u00e1nchez P, Mart\u00ednez-Mart\u00ednez M, Fuentes B, Cuesta MV, Cu\u00e9llar-Gamboa L, Idrovo-Freire L, Fern\u00e1ndez-Dominguez J, D\u00edez-Tejedor E (2011) Migraine and hypercoagulable states in ischemic stroke. Cephalalgia 31:1609\u20131617","journal-title":"Cephalalgia"},{"key":"3429_CR23","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1146\/annurev-physiol-030212-183717","volume":"75","author":"D Pietrobon","year":"2013","unstructured":"Pietrobon D, Moskowitz MA (2013) Pathophysiology of migraine. Annu Rev Physiol 75:365\u2013391","journal-title":"Annu Rev Physiol"},{"key":"3429_CR24","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/1129-2377-14-80","volume":"14","author":"S Sacco","year":"2013","unstructured":"Sacco S, Ripa P, Grassi D, Pistoia F, Ornello R, Carolei A, Kurth T (2013) Peripheral vascular dysfunction in migraine: a review. J Headache Pain 14:80","journal-title":"J Headache Pain"},{"key":"3429_CR25","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1136\/bmj.38302.504063.8F","volume":"330","author":"M Etminan","year":"2005","unstructured":"Etminan M, Takkouche B, Isorna FC, Samii A (2005) Risk of ischaemic stroke in people with migraine: systematic review and meta-analysis of observational studies. BMJ 330:63","journal-title":"BMJ"},{"key":"3429_CR26","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1007\/s11886-014-0524-1","volume":"16","author":"S Sacco","year":"2014","unstructured":"Sacco S, Kurth T (2014) Migraine and the risk for stroke and cardiovascular disease. Curr Cardiol Rep 16:524","journal-title":"Curr Cardiol Rep"},{"key":"3429_CR27","doi-asserted-by":"publisher","first-page":"2438","DOI":"10.1161\/STROKEAHA.107.488395","volume":"38","author":"LR MacClellan","year":"2007","unstructured":"MacClellan LR, Giles W, Cole J et al (2007) Probable migraine study. Stroke 38:2438\u20132445","journal-title":"Stroke"},{"key":"3429_CR28","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1111\/ene.13060","volume":"23","author":"J Norton","year":"2016","unstructured":"Norton J, Portet F, Gabelle A, Debette S, Ritchie K, Touchon J, Berr C (2016) Are migraine and non-migrainous headache risk factors for stroke in the elderly? Findings from a 12-year cohort follow-up. Eur J Neurol 23:1463\u20131470","journal-title":"Eur J Neurol"},{"key":"3429_CR29","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1212\/WNL.0b013e31821d74d5","volume":"76","author":"ME Wolf","year":"2011","unstructured":"Wolf ME, Szabo K, Griebe M, Forster A, Gass A, Hennerici MG, Kern R (2011) Clinical and MRI characteristics of acute migrainous infarction. Neurology 76:1911\u20131917","journal-title":"Neurology"},{"issue":"5","key":"3429_CR30","doi-asserted-by":"publisher","first-page":"489.e1","DOI":"10.1016\/j.ajog.2016.12.019","volume":"216","author":"SW Champaloux","year":"2017","unstructured":"Champaloux SW, Tepper NK, Monsour M, Curtis KM, Whiteman MK, Marchbanks PA, Jamieson DJ (2017) Use of combined hormonal contraceptives among women with migraines and risk of ischemic stroke. Am J Obstet Gynecol 216(5):489.e1\u2013489.e7","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"3429_CR31","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/head.13229","volume":"58","author":"HU Sheikh","year":"2018","unstructured":"Sheikh HU, Pavlovic J, Loder E et al (2018) Risk of stroke associated with use of estrogen containing contraceptives in women with migraine: a systematic review. Headache 58(1):5\u201321","journal-title":"Headache"},{"key":"3429_CR32","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1001\/jama.291.4.427","volume":"291","author":"MC Kruit","year":"2004","unstructured":"Kruit MC, van Buchem MA, Hofman PAM et al (2004) Migraine as a risk factor for subclinical brain lesions. JAMA 291:427\u2013434","journal-title":"JAMA"},{"key":"3429_CR33","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c3666","volume":"341","author":"S Debette","year":"2010","unstructured":"Debette S, Markus HS (2010) The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ 341:c3666","journal-title":"BMJ"},{"key":"3429_CR34","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1001\/jama.291.4.493","volume":"291","author":"RB Lipton","year":"2004","unstructured":"Lipton RB, Pan J (2004) Is migraine a progressive brain disease? JAMA 291:493\u2013494","journal-title":"JAMA"},{"key":"3429_CR35","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1212\/WNL.0b013e3182a6cb32","volume":"81","author":"A Bashir","year":"2013","unstructured":"Bashir A, Lipton RB, Ashina S, Ashina M (2013) Migraine and structural changes in the brain: a systematic review and meta-analysis. Neurology 81:1260\u20131268","journal-title":"Neurology"},{"key":"3429_CR36","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1093\/brain\/aww099","volume":"139","author":"D Gaist","year":"2016","unstructured":"Gaist D, Garde E, Blaabjerg M, Nielsen HH, Kr\u00f8ig\u00e5rd T, \u00d8stergaard K, M\u00f8ller HS, Hjelmborg J, Madsen CG, Iversen P, Kyvik KO, Siebner HR, Ashina M (2016) Migraine with aura and risk of silent brain infarcts and white matter hyperintensities: an MRI study. Brain 139:2015\u20132023","journal-title":"Brain"},{"key":"3429_CR37","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.1093\/brain\/awh542","volume":"128","author":"MC Kruit","year":"2005","unstructured":"Kruit MC, Launer LJ, Ferrari MD et al (2005) Infarcts in the posterior circulation territory in migraine. the population-based MRI CAMERA study. Brain J Neurol 128:2068\u20132077","journal-title":"Brain J Neurol"},{"key":"3429_CR38","doi-asserted-by":"publisher","first-page":"c7357","DOI":"10.1136\/bmj.c7357","volume":"342","author":"T Kurth","year":"2011","unstructured":"Kurth T, Mohamed S, Maillard P et al (2011) Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study. BMJ 342:c7357","journal-title":"BMJ"},{"key":"3429_CR39","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1161\/STROKEAHA.114.005447","volume":"45","author":"T Monteith","year":"2014","unstructured":"Monteith T, Gardener H, Rundek T et al (2014) Migraine, white matter hyperintensities, and subclinical brain infarction in a diverse community: the northern Manhattan study. Stroke J Cereb Circ 45:1830\u20131832","journal-title":"Stroke J Cereb Circ"},{"key":"3429_CR40","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1161\/01.STR.32.6.1318","volume":"32","author":"LO Wahlund","year":"2001","unstructured":"Wahlund LO, Barkhof F, Fazekas F, Bronge L, Augustin M, Sj\u00f6gren M, Wallin A, Ader H, Leys D, Pantoni L, Pasquier F, Erkinjuntti T, Scheltens P, European Task Force on Age-Related White Matter Changes (2001) A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke 32:1318\u20131322","journal-title":"Stroke"},{"key":"3429_CR41","first-page":"1032","volume":"20","author":"F Hu","year":"2016","unstructured":"Hu F, Qian ZW (2016) Characteristic analysis of white matter lesions in migraine patients with MRI. Eur Rev Med Pharmacol Sci 20:1032\u20131036","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"3429_CR42","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1111\/j.1468-2982.2008.01554.x","volume":"28","author":"TJ Schwedt","year":"2008","unstructured":"Schwedt TJ, Demaerschalk BM, Dodick DW (2008) Patent foramen ovale and migraine: a quantitative systematic review. Cephalalgia 28:531\u2013540","journal-title":"Cephalalgia"},{"issue":"5","key":"3429_CR43","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1161\/STROKEAHA.117.020160","volume":"49","author":"Brian H. West","year":"2018","unstructured":"West BH, Noureddin N, Mamzhi Y et al (2018) Frequency of patent foramen ovale and migraine in patients with cryptogenic stroke. Stroke. \n                    https:\/\/doi.org\/10.1161\/STROKEAHA.117.020160","journal-title":"Stroke"},{"key":"3429_CR44","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1016\/j.jacc.2017.12.059","volume":"71","author":"MK Mojadidi","year":"2018","unstructured":"Mojadidi MK, Zaman MO, Elgendy IY, Mahmoud AN, Patel NK, Agarwal N, Tobis JM, Meier B (2018) Cryptogenic stroke and patent foramen ovale. J Am Coll Cardiol 71:1035\u20131043","journal-title":"J Am Coll Cardiol"},{"key":"3429_CR45","doi-asserted-by":"publisher","first-page":"2029","DOI":"10.1093\/eurheartj\/ehw027","volume":"37","author":"HP Mattle","year":"2016","unstructured":"Mattle HP, Evers S, Hildick-Smith D, Becker WJ, Baumgartner H, Chataway J, Gawel M, G\u00f6bel H, Heinze A, Horlick E, Malik I, Ray S, Zermansky A, Findling O, Windecker S, Meier B (2016) Percutaneous closure of patent foramen ovale in migraine with aura, a randomized controlled trial. Eur Heart J 37:2029\u20132036","journal-title":"Eur Heart J"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-018-3429-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10072-018-3429-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-018-3429-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T14:28:59Z","timestamp":1560781739000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10072-018-3429-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,28]]},"references-count":45,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["3429"],"URL":"https:\/\/doi.org\/10.1007\/s10072-018-3429-8","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,28]]},"assertion":[{"value":"28 May 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any study with human subjects performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}