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MS registries represent powerful tools to provide meaningful information on the burden, natural history, and long-term safety and effectiveness of treatments. Moreover, patients, physicians, industry, and policy makers have an active interest in real-world observational studies based on register data, as they have the potential to answer the questions that are most relevant to daily treatment decision-making. In 2014, the Italian MS Foundation, in collaboration with the Italian MS clinical centers, promoted and funded the creation of the Italian MS Register, a project in continuity with the existing Italian MS Database Network set up from 2001. Main objective of the Italian MS Register is to create an organized multicenter structure to collect data of all MS patients for better defining the disease epidemiology, improving quality of care, and promoting research projects in high-priority areas. 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The author inadvertently missed out to include her second affiliation.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2019","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Unfortunately in the original publication, the affiliation of the author Maria Pia Amato was incorrect. The author inadvertently missed out to include her second affiliation.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The Italian MS register was approved by the Ethics Committee of the University of Bari (Italy) as coordinator center and the local ethics committee of all participant centers.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"These authors declare the following: Amato MP has received research grants honoraria as a speaker and member of Advisory Boards from Biogen, Bayer, Novartis, Roche, Teva, Sanofi-Genzyme, Merck. Ghezzi A received honoraria for speaking and consultancy by Novartis, Genzyme, Roche, Merck Serono, Teva, Mylan. Bergamaschi R received honoraria for speaking from Bayer Schering, Biogen Idec, Genzyme, Merck Serono, Novartis, Sanofi-Aventis, Teva; research grants from Bayer Schering, Biogen Idec, Merck Serono, Novartis, Sanofi-Aventis, Teva; congress and travel\/accommodation expenses funded by Almirall, Bayer Schering, Biogen Idec, Genzyme, Merck Serono, Novartis, Roche, Sanofi-Aventis, Teva. Comi G received personal compensation for consulting services and\/or speaking activities from Novartis, Teva, Sanofi-Genzyme, Merck, Biogen, Roche, Almirall, Celgene, Forward Pharma, Medday, Excemed. Patti F received personal compensation for consulting services and\/or speaking activities by Adienne, Bayer, Biogen, Celgene, Merck, Novartis, Roche, Sanofi, Teva. Trojano MT has served on scientific Advisory Boards for Biogen, Novartis, Roche and Sanofi-Genzyme; has received speaker honoraria from Biogen, Sanofi-Genzyme, Merck Serono,Teva and Novartis; and has received research grants for her Institution from Biogen, Merck Serono and Novartis. Mario Alberto Battaglia, Maria Giovanna Marrosu, Paola Mosconi, Michela Ponzio, Vito Lepore, and Paola Zaratin declared no conflict.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}