{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:03:35Z","timestamp":1791407015560,"version":"4.3.3"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T00:00:00Z","timestamp":1593129600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T00:00:00Z","timestamp":1593129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1007\/s10072-020-04528-w","type":"journal-article","created":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T17:28:11Z","timestamp":1593192491000},"page":"167-173","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Social, professional and neuropsychiatric outcomes in patients with myasthenia gravis"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2821-9042","authenticated-orcid":false,"given":"Bruno Kusznir","family":"Vitturi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre In Han","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Pari","family":"Mitre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ada","family":"Pellegrinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berenice Cataldo Oliveira","family":"Valerio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,26]]},"reference":[{"key":"4528_CR1","doi-asserted-by":"publisher","first-page":"874680","DOI":"10.1155\/2012\/874680","volume":"2012","author":"A Jayam Trouth","year":"2012","unstructured":"Jayam Trouth A, Dabi A, Solieman N, Kurukumbi M, Kalyanam J (2012) Myasthenia gravis: a review. Autoimmune Dis 2012:874680\u2013874610. https:\/\/doi.org\/10.1155\/2012\/874680","journal-title":"Autoimmune Dis"},{"issue":"10","key":"4528_CR2","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1016\/S1474-4422(15)00145-3","volume":"4","author":"NE Gilhus","year":"2015","unstructured":"Gilhus NE, Verschuuren JJ (2015) Myasthenia gravis: subgroup classification and therapeutic strategies. Lancet Neurol 4(10):1023\u20131036. https:\/\/doi.org\/10.1016\/S1474-4422(15)00145-3","journal-title":"Lancet Neurol"},{"issue":"4","key":"4528_CR3","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1212\/WNL.0000000000002790","volume":"87","author":"DB Sanders","year":"2016","unstructured":"Sanders DB, Wolfe GI, Benatar M, Evoli A, Gilhus NE, Illa I, Kuntz N, Massey JM, Melms A, Murai H, Nicolle M, Palace J, Richman DP, Verschuuren J, Narayanaswami P (2016) International consensus guidance for management of myasthenia gravis: executive summary. Neurology. 87(4):419\u2013425. https:\/\/doi.org\/10.1212\/WNL.0000000000002790","journal-title":"Neurology."},{"issue":"2","key":"4528_CR4","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.ncl.2018.01.006","volume":"36","author":"C Barnett","year":"2018","unstructured":"Barnett C, Herbelin L, Dimachkie MM, Barohn RJ (2018) Measuring clinical treatment response in myasthenia gravis. Neurol Clin 36(2):339\u2013353. https:\/\/doi.org\/10.1016\/j.ncl.2018.01.006","journal-title":"Neurol Clin"},{"key":"4528_CR5","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s13760-019-01209-0","volume":"120","author":"BK Vitturi","year":"2019","unstructured":"Vitturi BK, Pellegrinelli A, Valerio BCO (2019) Medication adherence in patients with myasthenia gravis in Brazil: a cross-sectional study. Acta Neurol Belg 120:83\u201389. https:\/\/doi.org\/10.1007\/s13760-019-01209-0","journal-title":"Acta Neurol Belg"},{"issue":"1","key":"4528_CR6","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1212\/WNL.55.1.16","volume":"70","author":"A Jaretzki","year":"2000","unstructured":"Jaretzki A, Barohn RJ, Ernstoff RM, Kaminski HJ, Keesey JC, Penn AS, Sanders DB (2000) Myasthenia gravis: recommendations for clinical research standards. Ann Thorac Surg 70(1):327\u2013334. https:\/\/doi.org\/10.1212\/WNL.55.1.16","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"4528_CR7","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1212\/WNL.0b013e3181dc1b1e","volume":"55","author":"TM Burns","year":"2010","unstructured":"Burns TM, Conaway M, Sanders DB (2010) The MG composite: a valid and reliable outcome measure for myasthenia gravis. Neurology. 55(1):16\u201323. https:\/\/doi.org\/10.1212\/WNL.0b013e3181dc1b1e","journal-title":"Neurology."},{"issue":"6","key":"4528_CR8","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1002\/1097-4679(199111)47:6<756::AID-JCLP2270470605>3.0.CO;2-L","volume":"47","author":"NW Dahlem","year":"1991","unstructured":"Dahlem NW, Zimet GD, Walker RR (1991) The multidimensional scale of perceived social support: a confirmation study. J Clin Psychol 47(6):756\u2013761. https:\/\/doi.org\/10.1002\/1097-4679(199111)47:6<756::AID-JCLP2270470605>3.0.CO;2-L","journal-title":"J Clin Psychol"},{"issue":"6","key":"4528_CR9","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","author":"AS Zigmond","year":"1983","unstructured":"Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361\u2013370. https:\/\/doi.org\/10.1111\/j.1600-0447.1983.tb09716.x","journal-title":"Acta Psychiatr Scand"},{"issue":"2","key":"4528_CR10","doi-asserted-by":"publisher","first-page":"e013278","DOI":"10.1136\/bmjopen-2016-013278","volume":"7","author":"Y Nagane","year":"2017","unstructured":"Nagane Y, Murai H, Imai T, Yamamoto D, Tsuda E, Minami N, Suzuki Y, Kanai T, Uzawa A, Kawaguchi N, Masuda M, Konno S, Suzuki H, Aoki M, Utsugisawa K (2017) Social disadvantages associated with myasthenia gravis and its treatment: a multicentre cross-sectional study. BMJ Open 7(2):e013278. https:\/\/doi.org\/10.1136\/bmjopen-2016-013278","journal-title":"BMJ Open"},{"issue":"5","key":"4528_CR11","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s10072-010-0285-6","volume":"31","author":"K Kulkantrakorn","year":"2010","unstructured":"Kulkantrakorn K, Sawanyawisuth K, Tiamkao S (2010) Factors correlating quality of life in patients with myasthenia gravis. Neurol Sci 31(5):571\u2013573. https:\/\/doi.org\/10.1007\/s10072-010-0285-6","journal-title":"Neurol Sci"},{"key":"4528_CR12","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1186\/1477-7525-8-129","volume":"8","author":"S Twork","year":"2010","unstructured":"Twork S, Wiesmeth S, Klewer J, P\u00f6hlau D, Kugler J (2010) Quality of life and life circumstances in German myasthenia gravis patients. Health Qual Life Outcomes 8:129. https:\/\/doi.org\/10.1186\/1477-7525-8-129","journal-title":"Health Qual Life Outcomes"},{"issue":"7","key":"4528_CR13","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1016\/j.jocn.2015.01.022","volume":"22","author":"S Blum","year":"2015","unstructured":"Blum S, Lee D, Gillis D, McEniery DF, Reddel S, McCombe P (2015) Clinical features and impact of myasthenia gravis disease in Australian patients. J Clin Neurosci 22(7):1164\u20131169. https:\/\/doi.org\/10.1016\/j.jocn.2015.01.022","journal-title":"J Clin Neurosci"},{"issue":"4","key":"4528_CR14","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1097\/CND.0000000000000257","volume":"20","author":"AN Boscoe","year":"2019","unstructured":"Boscoe AN, Xin H, L\u2019Italien GJ, Harris LA, Cutter GR (2019) Impact of refractory myasthenia gravis on health-related quality of life. J Clin Neuromuscul Dis 20(4):173\u2013181. https:\/\/doi.org\/10.1097\/CND.0000000000000257","journal-title":"J Clin Neuromuscul Dis"},{"issue":"2","key":"4528_CR15","doi-asserted-by":"publisher","first-page":"e0149356","DOI":"10.1371\/journal.pone.0149356","volume":"11","author":"K Kamenov","year":"2016","unstructured":"Kamenov K, Cabello M, Caballero FF, Cieza A, Sabariego C, Raggi A, Anczewska M, Pitk\u00e4nen T, Ayuso-Mateos JL (2016) Factors related to social support in neurological and mental disorders. PLoS One 11(2):e0149356. https:\/\/doi.org\/10.1371\/journal.pone.0149356","journal-title":"PLoS One"},{"issue":"4","key":"4528_CR16","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1007\/s00415-009-5389-7","volume":"257","author":"Y Winter","year":"2010","unstructured":"Winter Y, Von Campenhausen S, Gasser J et al (2010) Social and clinical determinants of quality of life in Parkinson\u2019s disease in Austria: a cohort study. J Neurol 257(4):638\u2013645. https:\/\/doi.org\/10.1007\/s00415-009-5389-7","journal-title":"J Neurol"},{"issue":"2","key":"4528_CR17","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1002\/mus.25493","volume":"56","author":"E Westerberg","year":"2017","unstructured":"Westerberg E, Molin CJ, Lindblad I, Emtner M, Punga AR (2017) Physical exercise in myasthenia gravis is safe and improves neuromuscular parameters and physical performance-based measures: a pilot study. Muscle Nerve 56(2):207\u2013214. https:\/\/doi.org\/10.1002\/mus.25493","journal-title":"Muscle Nerve"},{"issue":"31","key":"4528_CR18","doi-asserted-by":"publisher","first-page":"e11510","DOI":"10.1097\/MD.0000000000011510","volume":"97","author":"E Westerberg","year":"2018","unstructured":"Westerberg E, Molin CJ, Nees SS, Widenfalk J, Punga AR (2018) The impact of physical exercise on neuromuscular function in Myasthenia gravis patients: a single-subject design study. Med (United States) 97(31):e11510. https:\/\/doi.org\/10.1097\/MD.0000000000011510","journal-title":"Med (United States)"},{"issue":"11","key":"4528_CR19","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/S0003-9993(23)00011-4","volume":"74","author":"EL Lohi","year":"1993","unstructured":"Lohi EL, Lindberg C, Andersen O (1993) Physical training effects in myasthenia gravis. Arch Phys Med Rehabil 74(11):1178\u20131180","journal-title":"Arch Phys Med Rehabil"},{"issue":"11","key":"4528_CR20","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.1016\/j.apmr.2007.07.024","volume":"88","author":"EH Cup","year":"2007","unstructured":"Cup EH, Pieterse AJ, ten Broek-Pastoor JM, Munneke M, van Engelen BG, Hendricks HT, van der Wilt GJ, Oostendorp RA (2007) Exercise therapy and other types of physical therapy for patients with neuromuscular diseases: a systematic review. Arch Phys Med Rehabil 88(11):1452\u20131464. https:\/\/doi.org\/10.1016\/j.apmr.2007.07.024","journal-title":"Arch Phys Med Rehabil"},{"issue":"6","key":"4528_CR21","doi-asserted-by":"publisher","first-page":"473","DOI":"10.2165\/00023210-200721060-00004","volume":"21","author":"IB Kulaksizoglu","year":"2007","unstructured":"Kulaksizoglu IB (2007) Mood and anxiety disorders in patients with myasthenia gravis: aetiology, diagnosis and treatment. CNS Drugs 21(6):473\u2013481. https:\/\/doi.org\/10.2165\/00023210-200721060-00004","journal-title":"CNS Drugs"},{"issue":"2A","key":"4528_CR22","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1590\/s0004-282x2011000200006","volume":"69","author":"MI Ybarra","year":"2011","unstructured":"Ybarra MI, Kummer A, Frota ERC, de Oliveira JT, Gomez RS, Teixeira AL (2011) Psychiatric disorders in myasthenia gravis. Arq Neuropsiquiatr 69(2A):176\u2013179. https:\/\/doi.org\/10.1590\/s0004-282x2011000200006","journal-title":"Arq Neuropsiquiatr"},{"key":"4528_CR23","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.jocn.2019.08.027","volume":"69","author":"BK Vitturi","year":"2019","unstructured":"Vitturi BK, Nascimento BAC, Alves BR, de Campos FSC, Torigoe DY (2019) Cognitive impairment in patients with rheumatoid arthritis. J Clin Neurosci 69:81\u201387. https:\/\/doi.org\/10.1016\/j.jocn.2019.08.027","journal-title":"J Clin Neurosci"},{"issue":"11","key":"4528_CR24","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1111\/j.1525-1497.2006.00586.x","volume":"21","author":"IM Kronish","year":"2006","unstructured":"Kronish IM, Rieckmann N, Halm EA, Shimbo D, Vorchheimer D, Haas DC, Davidson KW (2006) Persistent depression affects adherence to secondary prevention behaviors after acute coronary syndromes. J Gen Intern Med 21(11):1178\u20131183. https:\/\/doi.org\/10.1111\/j.1525-1497.2006.00586.x","journal-title":"J Gen Intern Med"},{"issue":"2A","key":"4528_CR25","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1590\/s0004-282x2009000200006","volume":"67","author":"P Scalzo","year":"2009","unstructured":"Scalzo P, Kummer A, Cardoso F, Teixeira AL (2009) Depressive symptoms and perception of quality of life in Parkinson\u2019s disease. Arq Neuropsiquiatr 67(2A):203\u2013208. https:\/\/doi.org\/10.1590\/s0004-282x2009000200006","journal-title":"Arq Neuropsiquiatr"},{"key":"4528_CR26","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s13760-019-01102-w","volume":"0123456789","author":"UK Misra","year":"2019","unstructured":"Misra UK, Kalita J, Singh VK, Kumar S (2019) A study of comorbidities in myasthenia gravis. Acta Neurol Belg 0123456789:59\u201364. https:\/\/doi.org\/10.1007\/s13760-019-01102-w","journal-title":"Acta Neurol Belg"},{"issue":"1","key":"4528_CR27","doi-asserted-by":"publisher","first-page":"17","DOI":"10.4088\/PCC.v03n0104","volume":"3","author":"ES Brown","year":"2001","unstructured":"Brown ES, Chandler PA (2001) Mood and cognitive changes during systemic corticosteroid therapy. Prim Care Companion J Clin Psychiatry 3(1):17\u201321. https:\/\/doi.org\/10.4088\/PCC.v03n0104","journal-title":"Prim Care Companion J Clin Psychiatry"},{"issue":"2","key":"4528_CR28","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0022-510X(99)00205-1","volume":"170","author":"JC Keesey","year":"1999","unstructured":"Keesey JC (1999) Does myasthenia gravis affect the brain? J Neurol Sci 170(2):77\u201389. https:\/\/doi.org\/10.1016\/S0022-510X(99)00205-1","journal-title":"J Neurol Sci"},{"issue":"4","key":"4528_CR29","doi-asserted-by":"publisher","first-page":"295","DOI":"10.4274\/npa.y5611","volume":"50","author":"F Aysal","year":"2013","unstructured":"Aysal F, Karamustafalio\u01e7lu O, \u00d6z\u00e7elik B et al (2013) The relationship of symptoms of anxiety and depression with disease severity and treatment modality in myasthenia gravis: a cross-sectional study. Noropsikiyatri Ars 50(4):295\u2013300. https:\/\/doi.org\/10.4274\/npa.y5611","journal-title":"Noropsikiyatri Ars"},{"issue":"2","key":"4528_CR30","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1002\/mus.26507","volume":"60","author":"E Santos","year":"2019","unstructured":"Santos E, Bettencourt A, Duarte S, Gabriel D, Oliveira V, da Silva AM, Costa PP, Lopes C, Gon\u00e7alves G, da Silva BM, Leite MI (2019) Refractory myasthenia gravis: characteristics of a Portuguese cohort. Muscle Nerve 60(2):188\u2013191. https:\/\/doi.org\/10.1002\/mus.26507","journal-title":"Muscle Nerve"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-020-04528-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-020-04528-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-020-04528-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T00:16:45Z","timestamp":1696292205000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-020-04528-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,26]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["4528"],"URL":"https:\/\/doi.org\/10.1007\/s10072-020-04528-w","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,26]]},"assertion":[{"value":"6 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 June 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"None.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}