{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:15:13Z","timestamp":1790673313634,"version":"4.1.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T00:00:00Z","timestamp":1603324800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T00:00:00Z","timestamp":1603324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1007\/s10072-020-04841-4","type":"journal-article","created":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T20:05:42Z","timestamp":1603397142000},"page":"1139-1143","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Transcranial magnetic resonance-guided focused ultrasound thalamotomy as a safe treatment option in multiple sclerosis patients with essential tremor"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4088-2020","authenticated-orcid":false,"given":"Cesare","family":"Gagliardo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Ragonese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo Domenico","family":"Iacopino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Salemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Midiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"D\u2019Amelio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,22]]},"reference":[{"issue":"8","key":"4841_CR1","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1056\/NEJMoa1600159","volume":"375","author":"WJ Elias","year":"2016","unstructured":"Elias WJ, Lipsman N, Ondo WG, Ghanouni P, Kim YG, Lee W, Schwartz M, Hynynen K, Lozano AM, Shah BB, Huss D, Dallapiazza RF, Gwinn R, Witt J, Ro S, Eisenberg HM, Fishman PS, Gandhi D, Halpern CH, Chuang R, Butts Pauly K, Tierney TS, Hayes MT, Cosgrove GR, Yamaguchi T, Abe K, Taira T, Chang JW (2016) A randomized trial of focused ultrasound thalamotomy for essential tremor. N Engl J Med 375(8):730\u2013739","journal-title":"N Engl J Med"},{"issue":"12","key":"4841_CR2","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1001\/jamaneurol.2017.3098","volume":"74","author":"AE Bond","year":"2017","unstructured":"Bond AE, Shah BB, Huss DS, Dallapiazza RF, Warren A, Harrison MB, Sperling SA, Wang XQ, Gwinn R, Witt J, Ro S, Elias WJ (2017) Safety and efficacy of focused ultrasound thalamotomy for patients with medication-refractory, tremor-dominant parkinson disease: a randomized clinical trial. JAMA Neurol 74(12):1412\u20131418","journal-title":"JAMA Neurol"},{"key":"4841_CR3","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/2050-5736-1-3","volume":"1","author":"D Moser","year":"2013","unstructured":"Moser D, Zadicario E, Schiff G, Jeanmonod D (2013) MR-guided focused ultrasound technique in functional neurosurgery: targeting accuracy. J Ther Ultrasound 1:3","journal-title":"J Ther Ultrasound"},{"issue":"8","key":"4841_CR4","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1212\/WNL.0000000000004268","volume":"89","author":"A Fasano","year":"2017","unstructured":"Fasano A, Llinas M, Munhoz RP, Hlasny E, Kucharczyk W, Lozano AM (2017) MRI-guided focused ultrasound thalamotomy in non-ET tremor syndromes. Neurology. 89(8):771\u2013775","journal-title":"Neurology."},{"key":"4841_CR5","doi-asserted-by":"crossref","unstructured":"Manez-Miro JU, Martinez-Fernandez R, Del Alamo M, Pineda-Pardo JA, Fernandez-Rodriguez B, Alonso-Frech F, et al. Focused ultrasound thalamotomy for multiple sclerosis-associated tremor. Mult Scler 26(7):855\u2013858","DOI":"10.1177\/1352458519861597"},{"key":"4841_CR6","doi-asserted-by":"crossref","unstructured":"Gagliardo C, Midiri M, Cannella R, Napoli A, Wragg P, Collura G, Marrale M, Vincenzo Bartolotta T, Catalano C, Lagalla R (2019) Transcranial magnetic resonance-guided focused ultrasound surgery at 1.5T: a technical note. Neuroradiol J 32(2):132\u2013138","DOI":"10.1177\/1971400918818743"},{"key":"4841_CR7","doi-asserted-by":"crossref","unstructured":"Gagliardo C, Marrale M, D'Angelo C, Cannella R, Collura G, Iacopino G, et al (2020) Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound Treatment at 1.5 T: A retrospective study on treatment- and patient-related parameters obtained from 52 procedures. Front Phys 7","DOI":"10.3389\/fphy.2019.00223"},{"key":"4841_CR8","doi-asserted-by":"crossref","unstructured":"Gagliardo C, Cannella R, Quarrella C, D\u2019Amelio M, Napoli A, Bartolotta TV, et al (2020) Intraoperative imaging findings in transcranial MR imaging-guided focused ultrasound treatment at 1.5T may accurately detect typical lesional findings correlated with sonication parameters. Eur Radiol","DOI":"10.1007\/s00330-020-06712-0"},{"issue":"8","key":"4841_CR9","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1177\/1352458517694432","volume":"23","author":"G Kobelt","year":"2017","unstructured":"Kobelt G, Thompson A, Berg J, Gannedahl M, Eriksson J, Group MS et al (2017) New insights into the burden and costs of multiple sclerosis in Europe. Mult Scler 23(8):1123\u20131136","journal-title":"Mult Scler"},{"key":"4841_CR10","doi-asserted-by":"crossref","unstructured":"Brandmeir NJ, Murray A, Cheyuo C, Ferari C, Rezai AR (2019) Deep brain stimulation for multiple sclerosis tremor: a meta-analysis. Neuromodulation: Technology at the Neural Interface 23:463\u2013468","DOI":"10.1111\/ner.13063"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-020-04841-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-020-04841-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-020-04841-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T00:03:49Z","timestamp":1634861029000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-020-04841-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,22]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["4841"],"URL":"https:\/\/doi.org\/10.1007\/s10072-020-04841-4","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,22]]},"assertion":[{"value":"15 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Written informed consent was obtained from all subjects (patients) in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The scientific guarantor of this publication is Dr. Cesare Gagliardo (Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Palermo, Italy).","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}}]}}