{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:49:33Z","timestamp":1777456173343,"version":"3.51.4"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Rosette-forming glioneuronal tumor (RGNT) is a rare variety of slow growing mixed glioneuronal tumor involving primarily fourth ventricular region. This is a comprehensive analysis of a 22-year-old woman with RGNT composed of mainly cystic components. In addition, the case showed multiple lesions located in brain parenchyma which mimicked cerebral cysticercosis. Here, we analyzed this case and listed some characteristics of RGNTs in reported literature which occurring in atypical locations for further understanding it.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case report<\/jats:title>\n                <jats:p>A 22-year-old woman presented with a history of transient dizziness, nausea, and vomiting. Magnetic resonance imaging (MRI) showed multiple cystic lesions in brain parenchyma and then the patient was diagnosed with cerebral cysticercosis possibility. Empirical anti-infective therapy in addition to a follow-up post 2 weeks of MRI examination showed the lesions unchanged. Finally, a biopsy of the right cerebellar hemisphere lesions verified RGNT.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>RGNT is an uncommon tumor classified as grade I glioma by World Health Organization (WHO) with slightly longer course. The imaging findings of RGNT are not specific especially in atypical areas. RGNT is rare, but we should also consider the possibility in diagnosis and differential diagnosis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10072-021-05199-x","type":"journal-article","created":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T20:02:21Z","timestamp":1621540941000},"page":"4301-4308","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The rosette-forming glioneuronal tumor mimicked cerebral cysticercosis: a case report"],"prefix":"10.1007","volume":"42","author":[{"given":"Dan","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ailan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nickita T. L.","family":"Benons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7703-2789","authenticated-orcid":false,"given":"Shuguang","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,20]]},"reference":[{"key":"5199_CR1","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1097\/00000478-200205000-00004","volume":"26","author":"T Komori","year":"2002","unstructured":"Komori T, Scheithauer BW, Hirose T (2002) A rosette-forming glioneuronal tumor of the fourth ventricle: infratentorial form of dysembryoplastic neuroepithelial tumor? Am J Surg Pathol 26:582\u2013591","journal-title":"Am J Surg Pathol"},{"key":"5199_CR2","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/s12094-019-02179-8","volume":"22","author":"CT Anyanwu","year":"2020","unstructured":"Anyanwu CT, Robinson TM, Huang JH (2020) Rosette-forming glioneuronal tumor: an update. Clin Transl Oncol 22:623\u2013630","journal-title":"Clin Transl Oncol"},{"key":"5199_CR3","doi-asserted-by":"publisher","first-page":"109175","DOI":"10.18632\/oncotarget.22646","volume":"8","author":"C Yang","year":"2017","unstructured":"Yang C, Fang J, Li G, Li S, Ha T, Wang J, Yang B, Yang J, Xu Y (2017) Histopathological, molecular, clinical and radiological characterization of rosette-forming glioneuronal tumor in the central nervous system. Oncotarget 8:109175\u2013109190","journal-title":"Oncotarget"},{"key":"5199_CR4","doi-asserted-by":"publisher","unstructured":"Wilson CP, Chakraborty AR, Pelargos PE, Shi HH, Milton CK, Sung S, McCoy T, Peterson JE, Glenn CA (2020) Rosette-forming glioneuronal tumor: an illustrative case and a systematic review. Neuro-oncol Adv 2. https:\/\/doi.org\/10.1093\/noajnl\/vdaa116","DOI":"10.1093\/noajnl\/vdaa116"},{"key":"5199_CR5","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.wneu.2019.10.017","volume":"133","author":"M Morassi","year":"2020","unstructured":"Morassi M, Vivaldi O, Cobelli M, Liserre B, Zorzi F, Bn\u00e0 C (2020) A multifocal glioneuronal tumor with RGNT-like morphology occupying the supratentorial ventricular system and infiltrating the brain parenchyma. World Neurosurg 133:196\u2013200","journal-title":"World Neurosurg"},{"key":"5199_CR6","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.wneu.2019.02.003","volume":"125","author":"A Sekar","year":"2019","unstructured":"Sekar A, Rudrappa S, Gopal S, Ghosal N, Rai A (2019) Rosette-forming glioneuronal tumor in opticochiasmatic region-novel entity in new location. World Neurosurg 125:253\u2013256","journal-title":"World Neurosurg"},{"key":"5199_CR7","doi-asserted-by":"publisher","first-page":"2867","DOI":"10.1007\/s00381-020-04575-w","volume":"36","author":"Y Al Krinawe","year":"2020","unstructured":"Al Krinawe Y, Esmaeilzadeh M, Hartmann C et al (2020) Pediatric rosette-forming glioneuronal tumor of the septum pellucidum. Child's Nerv Syst 36:2867\u20132870","journal-title":"Child's Nerv Syst"},{"key":"5199_CR8","doi-asserted-by":"publisher","first-page":"e18271","DOI":"10.1097\/MD.0000000000018271","volume":"98","author":"S Hamauchi","year":"2019","unstructured":"Hamauchi S, Tanino M, Hida K, Sasamori T, Yano S, Tanaka S (2019) Spinal rosette-forming glioneuronal tumor: a case report. Medicine 98:e18271. https:\/\/doi.org\/10.1097\/MD.0000000000018271","journal-title":"Medicine"},{"key":"5199_CR9","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.wneu.2018.08.035","volume":"119","author":"A Collin","year":"2018","unstructured":"Collin A, Adle-Biassette H, Lecler A (2018) Rosette-forming glioneuronal tumor of spinal cord. World Neurosurg 119:242\u2013243","journal-title":"World Neurosurg"},{"key":"5199_CR10","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1111\/j.1440-1789.2010.01168.x","volume":"31","author":"E Matyja","year":"2011","unstructured":"Matyja E, Grajkowska W, Nauman P, Ozieblo A, Bonicki W (2011) Rosette-forming glioneuronal tumor of the fourth ventricle with advanced microvascular proliferation--a case report. Neuropathology 31:427\u2013432","journal-title":"Neuropathology"},{"key":"5199_CR11","doi-asserted-by":"publisher","first-page":"129","DOI":"10.3171\/jns.2006.105.1.129","volume":"105","author":"M Johnson","year":"2006","unstructured":"Johnson M, Pace J, Burroughs JF (2006) Fourth ventricle rosette-forming glioneuronal tumor. Case report. J Neurosurg 105:129\u2013131","journal-title":"J Neurosurg"},{"key":"5199_CR12","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1007\/s00330-015-3808-y","volume":"26","author":"G Medhi","year":"2016","unstructured":"Medhi G, Prasad C, Saini J, Pendharkar H, Bhat MD, Pandey P, Muthane Y (2016) Imaging features of rosette-forming glioneuronal tumours (RGNTs): a series of seven cases. Eur Radiol 26:262\u2013270","journal-title":"Eur Radiol"},{"key":"5199_CR13","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1007\/s00234-012-1010-3","volume":"54","author":"S Gaudino","year":"2012","unstructured":"Gaudino S, Quaglio FR, Schiarelli C, Martucci M, Tartaglione T, Gualano MR, di Lella GM, Colosimo C (2012) Spontaneous modifications of contrast enhancement in childhood non-cerebellar pilocytic astrocytomas. Neuroradiology 54:989\u2013995","journal-title":"Neuroradiology"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-021-05199-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-021-05199-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-021-05199-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T03:39:24Z","timestamp":1631763564000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-021-05199-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,20]]},"references-count":13,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["5199"],"URL":"https:\/\/doi.org\/10.1007\/s10072-021-05199-x","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,20]]},"assertion":[{"value":"10 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with humans.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"We would like to state that the informed consent has been obtained from the patient.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}