{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T19:41:14Z","timestamp":1776109274499,"version":"3.50.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T00:00:00Z","timestamp":1621036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T00:00:00Z","timestamp":1621036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s10072-021-05236-9","type":"journal-article","created":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T13:02:44Z","timestamp":1621083764000},"page":"541-547","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Is new daily persistent headache a fallout of somatization? An observational study"],"prefix":"10.1007","volume":"43","author":[{"given":"Ravi","family":"Uniyal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit","family":"Chhirolya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adarsh","family":"Tripathi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhakar","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1132-5372","authenticated-orcid":false,"given":"Vimal Kumar","family":"Paliwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,15]]},"reference":[{"key":"5236_CR1","doi-asserted-by":"publisher","first-page":"679","DOI":"10.4103\/0028-3886.232291","volume":"66","author":"R Uniyal","year":"2018","unstructured":"Uniyal R, Paliwal VK, Anand S, Ambesh P (2018) New daily persistent headache: an evolving entity. Neurology India 66:679","journal-title":"Neurology India"},{"key":"5236_CR2","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1111\/j.1526-4610.2012.02278.x","volume":"52","author":"N Li","year":"2012","unstructured":"Li N, Wang J, Huang Q, Tan G, Chen L, Zhou J (2012) Clinical features of new daily persistent headache in a tertiary outpatient population. Headache: The Journal of Head and Face Pain 52:1546\u20131552","journal-title":"Headache: The Journal of Head and Face Pain"},{"key":"5236_CR3","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1111\/j.1526-4610.2011.01872.x","volume":"51","author":"PJ Goadsby","year":"2011","unstructured":"Goadsby PJ (2011) New daily persistent headache: a syndrome not a discrete disorder. Headache: The Journal of Head and Face Pain 51:650\u2013653","journal-title":"Headache: The Journal of Head and Face Pain"},{"key":"5236_CR4","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1007\/s11916-014-0431-6","volume":"18","author":"TD Rozen","year":"2014","unstructured":"Rozen TD (2014) New daily persistent headache: an update. Current pain and headache reports 18:431","journal-title":"Current pain and headache reports"},{"key":"5236_CR5","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1111\/j.1468-2982.2008.01647.x","volume":"29","author":"E Kung","year":"2009","unstructured":"Kung E, Tepper SJ, Rapoport AM, Sheftell FD, Bigal ME (2009) New daily persistent headache in the paediatric population. Cephalalgia 29:17\u201322","journal-title":"Cephalalgia"},{"key":"5236_CR6","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s11910-010-0097-3","volume":"10","author":"EP Baron","year":"2010","unstructured":"Baron EP, Rothner AD (2010) New daily persistent headache in children and adolescents. Current neurology and neuroscience reports 10:127\u2013132","journal-title":"Current neurology and neuroscience reports"},{"key":"5236_CR7","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1212\/WNL.0b013e3181dad5de","volume":"74","author":"MS Robbins","year":"2010","unstructured":"Robbins MS, Grosberg BM, Napchan U, Crystal SC, Lipton RB (2010) Clinical and prognostic subforms of new daily-persistent headache. Neurology 74:1358\u20131364","journal-title":"Neurology"},{"key":"5236_CR8","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s11940-016-0408-3","volume":"18","author":"H Nierenburg","year":"2016","unstructured":"Nierenburg H, Newman LC (2016) Update on new daily persistent headache. Current treatment options in neurology 18:25","journal-title":"Current treatment options in neurology"},{"key":"5236_CR9","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1046\/j.1468-2982.2002.00326.x","volume":"22","author":"D Li","year":"2002","unstructured":"Li D, Rozen TD (2002) The clinical characteristics of new daily persistent headache. Cephalalgia 22:66\u201369","journal-title":"Cephalalgia"},{"key":"5236_CR10","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/S0140-6736(87)90119-X","volume":"329","author":"F Diaz-Mitoma","year":"1987","unstructured":"Diaz-Mitoma F, Vanast W, Tyrrell DJ (1987) Increased frequency of Epstein-Barr virus excretion in patients with new daily persistent headaches. The Lancet 329:411\u2013415","journal-title":"The Lancet"},{"key":"5236_CR11","doi-asserted-by":"publisher","first-page":"530","DOI":"10.2169\/internalmedicine.32.530","volume":"32","author":"JR Santoni","year":"1993","unstructured":"Santoni JR, Santoni-Williams CJ (1993) Headache and painful lymphadenopathy in extracranial or systemic infection: Etiology of NewDaily Persistant Headaches. Internal Medicine 32:530\u2013532","journal-title":"Internal Medicine"},{"key":"5236_CR12","first-page":"828","volume":"45","author":"T Rozen","year":"2005","unstructured":"Rozen T, Roth J, Denenberg N (2005) Joint hypermobility as a predisposing factor for the development of new daily persistent headache. Headache 45:828\u2013829","journal-title":"Headache"},{"key":"5236_CR13","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s10194-019-1022-z","volume":"20","author":"N Yamani","year":"2019","unstructured":"Yamani N, Olesen J (2019) New daily persistent headache: a systematic review on an enigmatic disorder. The journal of headache and pain 20:80","journal-title":"The journal of headache and pain"},{"key":"5236_CR14","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1526-4610.2010.01812.x","volume":"51","author":"RW Evans","year":"2011","unstructured":"Evans RW, Seifert TD (2011) The challenge of new daily persistent headache. Headache: The Journal of Head and Face Pain 51:145\u2013154","journal-title":"Headache: The Journal of Head and Face Pain"},{"key":"5236_CR15","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1177\/0333102411403633","volume":"3","author":"MS Robbins","year":"2011","unstructured":"Robbins MS (2011) New daily-persistent headache and anxiety. Cephalalgia 3:875\u2013876","journal-title":"Cephalalgia"},{"key":"5236_CR16","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1007\/s10194-012-0461-6","volume":"13","author":"S Prakash","year":"2012","unstructured":"Prakash S, Saini S, Rana KR, Mahato P (2012) Refining clinical features and therapeutic options of new daily persistent headache: a retrospective study of 63 patients in India. The Journal of Headache and Pain 13:477\u2013485","journal-title":"The Journal of Headache and Pain"},{"key":"5236_CR17","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1177\/0333102410383588","volume":"31","author":"MF Peres","year":"2011","unstructured":"Peres MF, Lucchetti G, Mercante JP, Young WB (2011) New daily persistent headache and panic disorder. Cephalalgia 31:250\u2013253","journal-title":"Cephalalgia"},{"key":"5236_CR18","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1177\/0333102411424620","volume":"31","author":"KP Peng","year":"2011","unstructured":"Peng KP, Fuh JL, Yuan HK, Shia BC, Wang SJ (2011) New daily persistent headache: should migrainous features be incorporated? Cephalalgia 31:1561\u20131569","journal-title":"Cephalalgia"},{"key":"5236_CR19","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1002\/ejp.1000","volume":"21","author":"R Uniyal","year":"2017","unstructured":"Uniyal R, Paliwal VK, Tripathi A (2017) Psychiatric comorbidity in new daily persistent headache: a cross-sectional study. European Journal of Pain 21:1031\u20131038","journal-title":"European Journal of Pain"},{"key":"5236_CR20","doi-asserted-by":"publisher","first-page":"23","DOI":"10.31887\/DCNS.2018.20.1\/phenningsen","volume":"20","author":"P Henningsen","year":"2018","unstructured":"Henningsen P (2018) Management of somatic symptom disorder. Dialogues in clinical neuroscience 20:23","journal-title":"Dialogues in clinical neuroscience"},{"key":"5236_CR21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030269","volume":"3","author":"W Rief","year":"2006","unstructured":"Rief W, Heitm\u00fcller AM, Reisberg K, R\u00fcddel H (2006) Why reassurance fails in patients with unexplained symptoms\u2014an experimental investigation of remembered probabilities. PLoS Med 3:e269","journal-title":"PLoS Med"},{"key":"5236_CR22","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.jpsychores.2015.12.005","volume":"81","author":"ML Woud","year":"2016","unstructured":"Woud ML, Zhang XC, Becker ES, Zlomuzica A, Margraf J (2016) Catastrophizing misinterpretations predict somatoform-related symptoms and new onsets of somatoform disorders. Journal of psychosomatic research 81:31\u201337","journal-title":"Journal of psychosomatic research"},{"key":"5236_CR23","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2013","unstructured":"American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Pub, Washington","edition":"5"},{"key":"5236_CR24","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1001\/jamainternmed.2013.12179","volume":"174","author":"B Gierk","year":"2014","unstructured":"Gierk B, Kohlmann S, Kroenke K, Spangenberg L, Zenger M, Br\u00e4hler E, L\u00f6we B (2014) The somatic symptom scale-8 (SSS-8): a brief measure of somatic symptom burden. JAMA internal medicine 174:399\u2013407","journal-title":"JAMA internal medicine"},{"key":"5236_CR25","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1097\/PSY.0000000000000240","volume":"78","author":"A Toussaint","year":"2016","unstructured":"Toussaint A, Murray AM, Voigt K, Herzog A, Gierk B, Kroenke K, Rief W, Henningsen P, L\u00f6we B (2016) Development and validation of the somatic symptom disorder-B criteria scale (SSD-12). Psychosomatic medicine 78:5\u201312","journal-title":"Psychosomatic medicine"},{"key":"5236_CR26","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1097\/00006842-200203000-00008","volume":"64","author":"K Kroenke","year":"2002","unstructured":"Kroenke K, Spitzer RL, Williams JB (2002) The PHQ-15: validity of a new measure for evaluating the severity of somatic symptoms. Psychosomatic medicine 64:258\u2013266","journal-title":"Psychosomatic medicine"},{"key":"5236_CR27","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","volume":"166","author":"RL Spitzer","year":"2006","unstructured":"Spitzer RL, Kroenke K, Williams JB, L\u00f6we B (2006) A brief measure for assessing generalized anxiety disorder: the GAD-7. Archives of internal medicine 166:1092\u20131097","journal-title":"Archives of internal medicine"},{"key":"5236_CR28","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","volume":"16","author":"K Kroenke","year":"2001","unstructured":"Kroenke K, Spitzer RL, Williams JB (2001) The PHQ-9: validity of a brief depression severity measure. Journal of general internal medicine 16:606\u2013613","journal-title":"Journal of general internal medicine"},{"key":"5236_CR29","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1046\/j.1526-4610.1999.3903190.x","volume":"39","author":"J Castillo","year":"1999","unstructured":"Castillo J, Mu\u00f1oz P, Guitera V, Pascual J (1999) Epidemiology of chronic daily headache in the general population. Headache: The Journal of Head and Face Pain 39:190\u2013196","journal-title":"Headache: The Journal of Head and Face Pain"},{"key":"5236_CR30","doi-asserted-by":"publisher","first-page":"132","DOI":"10.4103\/0976-3147.112736","volume":"4","author":"AK Singh","year":"2013","unstructured":"Singh AK, Shukla R, Trivedi JK, Singh D (2013) Association of psychiatric co-morbidity and efficacy of treatment in chronic daily headache in Indian population. Journal of neurosciences in rural practice 4:132","journal-title":"Journal of neurosciences in rural practice"},{"key":"5236_CR31","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1586\/ern.09.34","volume":"9","author":"PJ Quartana","year":"2009","unstructured":"Quartana PJ, Campbell CM, Edwards RR (2009) Pain catastrophizing: a critical review. Expert review of neurotherapeutics 9:745\u2013758","journal-title":"Expert review of neurotherapeutics"},{"key":"5236_CR32","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1007\/BF02598318","volume":"6","author":"RC Smith","year":"1991","unstructured":"Smith RC (1991) Somatization disorder. Journal of general internal medicine 6:168\u2013175","journal-title":"Journal of general internal medicine"},{"key":"5236_CR33","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1016\/j.pnpbp.2011.05.016","volume":"35","author":"M Atmaca","year":"2011","unstructured":"Atmaca M, Sirlier B, Yildirim H, Kayali A (2011) Hippocampus and amygdalar volumes in patients with somatization disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 35:1699\u20131703","journal-title":"Progress in Neuro-Psychopharmacology and Biological Psychiatry"},{"key":"5236_CR34","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1136\/jnnp-2011-300776","volume":"83","author":"SJ van der Kruijs","year":"2012","unstructured":"van der Kruijs SJ, Bodde NM, Vaessen MJ, Lazeron RH, Vonck K, Boon P et al (2012) Functional connectivity of dissociation in patients with psychogenic non-epileptic seizures. Journal of Neurology, Neurosurgery & Psychiatry 83:239\u2013247","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"5236_CR35","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/j.nicl.2016.04.001","volume":"11","author":"M Boeckle","year":"2016","unstructured":"Boeckle M, Schrimpf M, Liegl G, Pieh C (2016) Neural correlates of somatoform disorders from a meta-analytic perspective on neuroimaging studies. NeuroImage: Clinical 11:606\u2013613","journal-title":"NeuroImage: Clinical"},{"key":"5236_CR36","doi-asserted-by":"publisher","first-page":"2283","DOI":"10.1007\/s11136-018-1894-4","volume":"27","author":"EJ Shim","year":"2018","unstructured":"Shim EJ, Park A, Park SP (2018) The relationship between alexithymia and headache impact: the role of somatization and pain catastrophizing. Quality of Life Research 27:2283\u20132294","journal-title":"Quality of Life Research"},{"key":"5236_CR37","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.jpsychores.2013.06.033","volume":"75","author":"JE Dimsdale","year":"2013","unstructured":"Dimsdale JE, Creed F, Escobar J, Sharpe M, Wulsin L, Barsky A, Lee S, Irwin MR, Levenson J (2013) Somatic symptom disorder: an important change in DSM. Journal of psychosomatic research 75:223\u2013228","journal-title":"Journal of psychosomatic research"},{"key":"5236_CR38","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1017\/S0033291799008417","volume":"29","author":"OYE Gureje","year":"1999","unstructured":"Gureje OYE, Simon GE (1999) The natural history of somatization in primary care. Psychological medicine 29:669\u2013676","journal-title":"Psychological medicine"},{"key":"5236_CR39","doi-asserted-by":"publisher","first-page":"e246","DOI":"10.3399\/bjgp19X701249","volume":"69","author":"K Lamahewa","year":"2019","unstructured":"Lamahewa K, Buszewicz M, Walters K, Marston L, Nazareth I (2019) Persistent unexplained physical symptoms: a prospective longitudinal cohort study in UK primary care. Br J Gen Pract 69:e246\u2013e253","journal-title":"Br J Gen Pract"},{"key":"5236_CR40","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1001\/archpsyc.56.1.90","volume":"56","author":"GE Simon","year":"1999","unstructured":"Simon GE, Gureje O (1999) Stability of somatization disorder and somatization symptoms among primary care patients. Archives of general psychiatry 56:90\u201395","journal-title":"Archives of general psychiatry"},{"key":"5236_CR41","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1177\/0333102415612766","volume":"36","author":"TD Rozen","year":"2016","unstructured":"Rozen TD (2016) New daily persistent headache: a lack of an association with white matter abnormalities on neuroimaging. Cephalalgia 36:987\u2013992","journal-title":"Cephalalgia"},{"key":"5236_CR42","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1111\/j.1468-2982.2009.01842.x","volume":"29","author":"RB Grande","year":"2009","unstructured":"Grande RB, Aaseth K, Lundqvist C, Russell MB (2009) Prevalence of new daily persistent headache in the general population. The Akershus study of chronic headache. Cephalalgia 29:1149\u20131155","journal-title":"Cephalalgia"},{"key":"5236_CR43","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1007\/s11916-010-0145-3","volume":"14","author":"MS Robbins","year":"2010","unstructured":"Robbins MS, Crystal SC (2010) New daily\u2013persistent headache versus tension-type headache. Current pain and headache reports 14:431\u2013435","journal-title":"Current pain and headache reports"},{"key":"5236_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11916-020-00892-6","volume":"24","author":"V Nieswand","year":"2020","unstructured":"Nieswand V, Richter M, Gossrau G (2020) Epidemiology of headache in children and adolescents\u2014another type of pandemia. Current Pain and Headache Reports 24:1\u201310","journal-title":"Current Pain and Headache Reports"},{"key":"5236_CR45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s10194-019-1022-z","volume":"20","author":"N Yamani","year":"2019","unstructured":"Yamani N, Olesen J (2019) New daily persistent headache: a systematic review on an enigmatic disorder. The journal of headache and pain 20:1\u20139","journal-title":"The journal of headache and pain"},{"key":"5236_CR46","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.jpsychores.2016.06.003","volume":"87","author":"SM van Geelen","year":"2016","unstructured":"van Geelen SM, Hagquist C (2016) Are the time trends in adolescent psychosomatic problems related to functional impairment in daily life? A 23-year study among 20,000 15\u201316 year olds in Sweden. Journal of psychosomatic research 87:50\u201356","journal-title":"Journal of psychosomatic research"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-021-05236-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-021-05236-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-021-05236-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T05:40:14Z","timestamp":1675316414000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-021-05236-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,15]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["5236"],"URL":"https:\/\/doi.org\/10.1007\/s10072-021-05236-9","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,15]]},"assertion":[{"value":"3 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Approval was obtained from the ethics committee of The Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. This study adheres to the tenets of the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent to participate in the study was obtained from all the participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}