{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T10:48:06Z","timestamp":1785322086469,"version":"3.55.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s10072-021-05322-y","type":"journal-article","created":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T20:02:21Z","timestamp":1621540941000},"page":"373-378","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Fatigue is related to depression in idiopathic dystonia"],"prefix":"10.1007","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1613-3831","authenticated-orcid":false,"given":"Svetlana","family":"Tomic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tihana Gilman","family":"Kuric","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zvonimir","family":"Popovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tea Mirosevic","family":"Zubonja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,20]]},"reference":[{"issue":"7","key":"5322_CR1","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1002\/mds.25475","volume":"28","author":"A Albanese","year":"2013","unstructured":"Albanese A, Bhatia K, Bressman SB, Delong MR, Fahn S, Fung VS, Hallett M, Jankovic J, Jinnah HA, Klein C, Lang AE, Mink JW, Teller JK (2013) Phenomenology and classification of dystonia: a consensus update. Mov Disord 28(7):863\u2013873. https:\/\/doi.org\/10.1002\/mds.25475","journal-title":"Mov Disord"},{"key":"5322_CR2","doi-asserted-by":"publisher","first-page":"506","DOI":"10.7916\/D8V69X3S","volume":"7","author":"HA Jinnah","year":"2017","unstructured":"Jinnah HA, Neychev V, Hess EJ (2017) The anatomical basis for dystonia: the motor network model. Tremor Other Hyperkinet Mov 7:506. https:\/\/doi.org\/10.7916\/D8V69X3S eCollection 2017","journal-title":"Tremor Other Hyperkinet Mov"},{"issue":"1","key":"5322_CR3","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/s41572-018-0023-6","volume":"4","author":"B Balint","year":"2018","unstructured":"Balint B, Mencacci NE, Valente EM, Pisani A, Rothwell J, Jankovic J, Vidailhet M, Bhatia KP (2018) Dystonia. Nat Rev Dis Primers 4(1):37. https:\/\/doi.org\/10.1038\/s41572-018-0023-6","journal-title":"Nat Rev Dis Primers"},{"key":"5322_CR4","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1111\/j.1755-5949.2010.00135.x","volume":"16","author":"G Di Giovanni","year":"2010","unstructured":"Di Giovanni G, Esposito E, Di Matteo V (2010) Role of serotonin in central dopamine dysfunction. CNS Neurosci Ther 16:179\u2013194. https:\/\/doi.org\/10.1111\/j.1755-5949.2010.00135.x","journal-title":"CNS Neurosci Ther"},{"issue":"13","key":"5322_CR5","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1002\/mds.25109","volume":"27","author":"C Pifl","year":"2012","unstructured":"Pifl C, Kish SJ, Hornykiewicz (2012) Thalamic noradrenaline in Parkinson\u2019s disease: deficits suggest role in motor and non-motor symptoms. Mov Disord 27(13):1618\u20131624. https:\/\/doi.org\/10.1002\/mds.25109","journal-title":"Mov Disord"},{"issue":"7","key":"5322_CR6","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1002\/mds.23709","volume":"26","author":"DJ Kuyper","year":"2011","unstructured":"Kuyper DJ, Parra V, Aerts S, Okun MS, Kluger BM (2011) The non-motor manifestations of dystonia: a systematic review. Mov Disord 26(7):1206\u20131217. https:\/\/doi.org\/10.1002\/mds.23709","journal-title":"Mov Disord"},{"issue":"10","key":"5322_CR7","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1007\/s00702-020-02245-4","volume":"127","author":"M Tinazzi","year":"2020","unstructured":"Tinazzi M, Erro R, Mascia MM, Esposito M, Ercoli T, Ferrazzano G, di Biasio F, Pellicciari R, Eleopra R, Bono F, Bertolasi L, Barone P, Scaglione CLM, Pisani A, Altavista MC, Cotelli MS, Ceravolo R, Cossu G, Zibetti M, Moja MC, Girlanda P, Maderna L, Albanese A, Petracca M, Magistrelli L, Misceo S, Minafra B, Romano M, Squintani GM, Modugno N, Aguggia M, Cassano D, Castagna A, Morgante F, Berardelli A, Defazio G (2020) Demographic and clinical determinants of neck pain in idiopathic cervical dystonia. J Neural Transm (Vienna) 127(10):1437\u20131439. https:\/\/doi.org\/10.1007\/s00702-020-02245-4","journal-title":"J Neural Transm (Vienna)"},{"issue":"4","key":"5322_CR8","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1007\/s13760-016-0634-1","volume":"116","author":"S Tomic","year":"2016","unstructured":"Tomic S, Petkovic I, Pucic T, Resan B, Juric S, Rotim T (2016) Cervical dystonia and quality of life. Acta Neurol Belg 116(4):589\u2013592. https:\/\/doi.org\/10.1007\/s13760-016-0634-1","journal-title":"Acta Neurol Belg"},{"key":"5322_CR9","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1016\/S0140-6736(04)15794-2","volume":"363","author":"A Chaudhuri","year":"2004","unstructured":"Chaudhuri A, Behan PO (2004) Fatigue in neurological disorders. Lancet 363:978\u2013988. https:\/\/doi.org\/10.1016\/S0140-6736(04)15794-2","journal-title":"Lancet"},{"issue":"5","key":"5322_CR10","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.pmrj.2010.03.028","volume":"2","author":"LA Jason","year":"2010","unstructured":"Jason LA, Evans M, Brown M, Porter N (2010) What is fatigue? Pathological and nonpathological fatigue. PM&R 2(5):327\u2013331. https:\/\/doi.org\/10.1016\/j.pmrj.2010.03.028","journal-title":"PM&R"},{"key":"5322_CR11","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/s0022-3999(02)00392-6","volume":"54","author":"HJ Michielsen","year":"2003","unstructured":"Michielsen HJ, De Vries J, Van Heck GL (2003) Psychometric qualities of a brief self-rated fatigue: the Fatigue Assessment Scale. J Psychosom Res 54:345\u2013352. https:\/\/doi.org\/10.1016\/s0022-3999(02)00392-6","journal-title":"J Psychosom Res"},{"key":"5322_CR12","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1093\/sleep\/14.6.540","volume":"14","author":"MW Johns","year":"1991","unstructured":"Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep 14:50\u201355","journal-title":"Sleep"},{"issue":"2","key":"5322_CR13","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","volume":"28","author":"DJ Buysse","year":"1989","unstructured":"Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28(2):193\u2013213. https:\/\/doi.org\/10.1016\/0165-1781(89)90047-4","journal-title":"Psychiatry Res"},{"issue":"3","key":"5322_CR14","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1207\/s15327752jpa6703_13","volume":"67","author":"AT Beck","year":"1996","unstructured":"Beck AT, Steer RA, Ball R, Ranieri W (1996) Comparison of Beck Depression Inventories IA and II in psychiatric outpatients. J Pers Assess 67(3):588\u2013597. https:\/\/doi.org\/10.1207\/s15327752jpa6703_13","journal-title":"J Pers Assess"},{"issue":"6","key":"5322_CR15","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1037\/0022-006x.56.6.893","volume":"56","author":"AT Beck","year":"1998","unstructured":"Beck AT, Epstein N, Brown G, Steer RA (1998) An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol 56(6):893\u2013897. https:\/\/doi.org\/10.1037\/0022-006x.56.6.893","journal-title":"J Consult Clin Psychol"},{"key":"5322_CR16","doi-asserted-by":"publisher","unstructured":"Han V, Skorvanek M, Smit M, Turcanova Koprusakova M, Hoekstra T, van Dijk JP, Tijssen MAJ, Gdovinova Z, Reijneveld SA (2020) Prevalence of non-motor symptoms and their association with quality of life in cervical dystonia. Acta Neurol Scand. https:\/\/doi.org\/10.1111\/ane.13304","DOI":"10.1111\/ane.13304"},{"issue":"4","key":"5322_CR17","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1002\/mdc3.12459","volume":"4","author":"M Smit","year":"2017","unstructured":"Smit M, Kamphuis ASJ, Bartels AL, Han V, Stewart RE, Zijdewind I, Tijssen MA (2017) Fatigue, sleep disturbances, and their influence on quality of life in cervical dystonia patients. Mov Disord Clin Pract 4(4):17\u201323. https:\/\/doi.org\/10.1002\/mdc3.12459","journal-title":"Mov Disord Clin Pract"},{"key":"5322_CR18","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.baga.2014.10.002","volume":"4","author":"L Klingelhoefer","year":"2014","unstructured":"Klingelhoefer L, Martino D, Martinez-Martin P, Sauerbiera A, Rizosa A, Jost W, Warnere TT, Chaudhuri KR (2014) Nonmotor symptoms and focal cervical dystonia: observations from 102 patients. Basal Ganglia 4:117\u2013120","journal-title":"Basal Ganglia"},{"key":"5322_CR19","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/s0022-3999(97)00291-2","volume":"45","author":"JH Loge","year":"1998","unstructured":"Loge JH, Ekeberg O, Kaasa S (1998) Fatigue in the general Norwegian population: normative data and associations. J Psychosom Res 45:53\u201365. https:\/\/doi.org\/10.1016\/s0022-3999(97)00291-2","journal-title":"J Psychosom Res"},{"key":"5322_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.comppsych.2016.08.004","volume":"71","author":"EC Corfield","year":"2016","unstructured":"Corfield EC, Martin NG, Nyholt DR (2016) Co-occurrence and symptomatology of fatigue and depression. Compr Psychiatry 71:1\u201310. https:\/\/doi.org\/10.1016\/j.comppsych.2016.08.004","journal-title":"Compr Psychiatry"},{"key":"5322_CR21","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Publishing, Washington,D.C.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"5322_CR22","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.comppsych.2014.09.007","volume":"56","author":"M Zimmerman","year":"2015","unstructured":"Zimmerman M, Ellison W, Young D, Chelminski I, Dalrymple K (2015) How many different ways do patients meet the diagnostic criteria for major depressive disorder? Compr Psychiatry 56:29\u201334. https:\/\/doi.org\/10.1016\/j.comppsych.2014.09.007","journal-title":"Compr Psychiatry"},{"issue":"3","key":"5322_CR23","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1177\/135245850000600308","volume":"6","author":"R Bakshi","year":"2000","unstructured":"Bakshi R, Shaikh ZA, Miletich RS, Czarnecki D, Dmochowski J, Henschel K, Janardhan V, Dubey N, Kinkel PR (2000) Fatigue in multiple sclerosis and its relationship to depression and neurologic disability. Mult Scler 6(3):181\u2013185. https:\/\/doi.org\/10.1177\/135245850000600308","journal-title":"Mult Scler"},{"issue":"5","key":"5322_CR24","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1017\/s0033291700037387","volume":"25","author":"R Fuhrer","year":"1995","unstructured":"Fuhrer R, Wessely S (1995) The epidemiology of fatigue and depression: a French primary-care study. Psychol Med 25(5):895\u2013905. https:\/\/doi.org\/10.1017\/s0033291700037387","journal-title":"Psychol Med"},{"key":"5322_CR25","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1017\/s0033291701004214","volume":"31","author":"AM Addington","year":"2001","unstructured":"Addington AM, Gallo JJ, Ford DE, Eaton WW (2001) Epidemiology of unexplained fatigue and major depression in the community: the Baltimore ECA Follow-up, 1981-1994. Psychol Med 31:1037\u20131044. https:\/\/doi.org\/10.1017\/s0033291701004214","journal-title":"Psychol Med"},{"key":"5322_CR26","doi-asserted-by":"publisher","first-page":"589","DOI":"10.3389\/fpsyt.2018.00589","volume":"9","author":"M Noda","year":"2018","unstructured":"Noda M, Ifuku M, Hossain MS, Katafuchi T (2018) Glial activation and expression of the serotonin transporter in chronic fatigue syndrome. Front Psychiatry 9:589. https:\/\/doi.org\/10.3389\/fpsyt.2018.00589","journal-title":"Front Psychiatry"},{"issue":"2","key":"5322_CR27","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.jad.2013.03.029","volume":"150","author":"M Maes","year":"2013","unstructured":"Maes M, Ringel K, Kubera M, Anderson G, Morris G, Galecki P, Geffard M (2013) In myalgic encephalomyelitis\/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation. J Affect Disord 150(2):223\u2013230. https:\/\/doi.org\/10.1016\/j.jad.2013.03.029","journal-title":"J Affect Disord"},{"key":"5322_CR28","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1124\/jpet.302.1.145","volume":"302","author":"MA Pelleymounter","year":"2002","unstructured":"Pelleymounter MA, Joppa M, Ling N, Foster AC (2002) Pharmacological evidence supporting a role for central corticotropin-releasing factor 2 receptors in behavioural, but not endocrine, responses to environmental stress. J Pharmacol Exp Ther 302:145\u2013152. https:\/\/doi.org\/10.1124\/jpet.302.1.145","journal-title":"J Pharmacol Exp Ther"},{"issue":"10","key":"5322_CR29","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1517\/14656560902988510","volume":"10","author":"CU Pae","year":"2009","unstructured":"Pae CU, Marks DM, Patkar AA, Masand PS, Luyten P, Serretti A (2009) Pharmacological treatment of chronic fatigue syndrome: focusing on the role of antidepressants. Expert Opin Pharmacother 10(10):1561\u20131570. https:\/\/doi.org\/10.1517\/14656560902988510","journal-title":"Expert Opin Pharmacother"},{"issue":"9","key":"5322_CR30","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1136\/jnnp-2013-306971","volume":"85","author":"VF Ramos","year":"2014","unstructured":"Ramos VF, Karp BI, Hallett M (2014) Tricks in dystonia: ordering the complexity. J Neurol Neurosurg Psychiatry 85(9):987\u2013993. https:\/\/doi.org\/10.1136\/jnnp-2013-306971","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"5322_CR31","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.parkreldis.2019.01.006","volume":"63","author":"S Dagostino","year":"2019","unstructured":"Dagostino S, Ercoli T, Gigante AF, Pellicciari R, Fadda L, Defazio G (2019) Sensory trick in upper limb dystonia. Parkinsonism Relat Disord 63:221\u2013223. https:\/\/doi.org\/10.1016\/j.parkreldis.2019.01.006","journal-title":"Parkinsonism Relat Disord"},{"key":"5322_CR32","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1093\/brain\/aws372","volume":"136","author":"M Tinazzi","year":"2013","unstructured":"Tinazzi M, Marotta A, Fasano A, Bove F, Bentivoglio AR, Squintani G, Pozzer L, Fiorio M (2013) Aristotle\u2019s illusion reveals interdigit functional somatosensory alterations in focal hand dystonia. Brain 136:782\u2013789. https:\/\/doi.org\/10.1093\/brain\/aws372","journal-title":"Brain"},{"key":"5322_CR33","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1111\/ene.12890","volume":"23","author":"A Macerollo","year":"2016","unstructured":"Macerollo A, Chen JC, Parees I, Sadnicka A, Kassavetis P, Bhatia KP, Kilner JM, Rothwell JC, Edwards MJ (2016) Abnormal movement-related suppression of sensory evoked potentials in upper limb dystonia. Eur J Neurol 23:562\u2013568. https:\/\/doi.org\/10.1111\/ene.12890","journal-title":"Eur J Neurol"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-021-05322-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-021-05322-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-021-05322-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T18:30:10Z","timestamp":1641234610000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-021-05322-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,20]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["5322"],"URL":"https:\/\/doi.org\/10.1007\/s10072-021-05322-y","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,20]]},"assertion":[{"value":"13 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Svetlana Tomic received speaking fee from AbbVie d.o.o., Pliva Hrvatska d.o.o., Phoenix Pharmacia d.o.o., Sanofi-Aventis Croatia d.o.o., Novartis Hrvatska d.o.o., Fresenius Kabi d.o.o., Makpharm d.o.o., Medis Adria d.o.o., and Merz Pharmaceuticals GmbH and has received travel support for congress from Medis Adria d.o.o.; Tihana Gilman Kuric received speaking fee from Novartis Hrvatska d.o.o. and has received travel support for congress from Medis Adria d.o.o. and Makpharm d.o.o; Zvonimir Popovic received speaking fee from Novartis Hrvatska d.o.o; Tea Mirosevic Zubonja received speaking fee from Novartis Hrvatska d.o.o, Roche d.o.o., Pliva Hrvatska d.o.o., and Merck d.o.o.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Approval was obtained from the Ethics committee of Osijek University Hospital Center. The procedures used in this study adhere to the tenets of the Declaration of Helsinki. Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}]}}