{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:57:43Z","timestamp":1790668663100,"version":"4.1.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1007\/s10072-022-06110-y","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T17:03:05Z","timestamp":1651683785000},"page":"4745-4752","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Olfactory dysfunction and striatal dopamine transporter binding in motor subtypes of Parkinson\u2019s disease"],"prefix":"10.1007","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4633-3340","authenticated-orcid":false,"given":"Fardin","family":"Nabizadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Sodeifian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasra","family":"Pirahesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,4]]},"reference":[{"issue":"7","key":"6110_CR1","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.amjmed.2019.03.001","volume":"132","author":"MT Hayes","year":"2019","unstructured":"Hayes MT (2019) Parkinson\u2019s disease and parkinsonism. Am J Med 132(7):802\u2013807. https:\/\/doi.org\/10.1016\/j.amjmed.2019.03.001","journal-title":"Am J Med"},{"issue":"6","key":"6110_CR2","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1001\/jama.2019.22360","volume":"323","author":"MJ Armstrong","year":"2020","unstructured":"Armstrong MJ, Okun MS (2020) Diagnosis and treatment of Parkinson disease: a review. JAMA 323(6):548\u2013560. https:\/\/doi.org\/10.1001\/jama.2019.22360","journal-title":"JAMA"},{"issue":"2","key":"6110_CR3","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/s0197-4580(02)00065-9","volume":"24","author":"H Braak","year":"2003","unstructured":"Braak H, Del Tredici K, R\u00fcb U, de Vos RA, Jansen Steur EN, Braak E (2003) Staging of brain pathology related to sporadic Parkinson\u2019s disease. Neurobiol Aging 24(2):197\u2013211. https:\/\/doi.org\/10.1016\/s0197-4580(02)00065-9","journal-title":"Neurobiol Aging"},{"key":"6110_CR4","doi-asserted-by":"publisher","first-page":"625171","DOI":"10.3389\/fnagi.2021.625171","volume":"13","author":"T Eek","year":"2021","unstructured":"Eek T, Larsson M, Dizdar N (2021) Odor recognition memory in Parkinson\u2019s disease: a systematic review. Front Aging Neurosci 13:625171\u2013625171. https:\/\/doi.org\/10.3389\/fnagi.2021.625171","journal-title":"Front Aging Neurosci"},{"issue":"9","key":"6110_CR5","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1002\/mds.26687","volume":"31","author":"M Rossi","year":"2016","unstructured":"Rossi M, Escobar AM, Bril A, Millar Vernetti P, De Palo JI, Cerquetti D, Merello M (2016) Motor features in Parkinson\u2019s disease with normal olfactory function. Mov Disord 31(9):1414\u20131417. https:\/\/doi.org\/10.1002\/mds.26687","journal-title":"Mov Disord"},{"issue":"2","key":"6110_CR6","doi-asserted-by":"publisher","first-page":"133","DOI":"10.14802\/jmd.19082","volume":"13","author":"HS Yoo","year":"2020","unstructured":"Yoo HS, Chung SJ, Lee YH, Ye BS, Sohn YH, Lee PH (2020) Association between olfactory deficit and motor and cognitive function in Parkinson\u2019s disease. J Mov Disord 13(2):133\u2013141. https:\/\/doi.org\/10.14802\/jmd.19082","journal-title":"J Mov Disord"},{"key":"6110_CR7","doi-asserted-by":"publisher","unstructured":"He R, Zhao Y, He Y, Zhou Y, Yang J, Zhou X, Zhu L, Zhou X, Liu Z, Xu Q, Sun Q, Tan J, Yan X, Tang B, Guo J (2020) Olfactory dysfunction predicts disease progression in Parkinson\u2019s disease a longitudinal study. Front Neurosci 14(1264). https:\/\/doi.org\/10.3389\/fnins.2020.569777","DOI":"10.3389\/fnins.2020.569777"},{"issue":"15","key":"6110_CR8","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1212\/wnl.0000000000001999","volume":"85","author":"DH Lee","year":"2015","unstructured":"Lee DH, Oh JS, Ham JH, Lee JJ, Lee I, Lee PH, Kim JS, Sohn YH (2015) Is normosmic Parkinson disease a unique clinical phenotype? Neurology 85(15):1270\u20131275. https:\/\/doi.org\/10.1212\/wnl.0000000000001999","journal-title":"Neurology"},{"key":"6110_CR9","doi-asserted-by":"publisher","unstructured":"Qian E, Huang Y (2019) Subtyping of Parkinson\u2019s disease - where are we up to? Aging Dis 10 (5) 1130\u20131139 https:\/\/doi.org\/10.14336\/AD.2019.0112","DOI":"10.14336\/AD.2019.0112"},{"issue":"10","key":"6110_CR10","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1212\/WNL.40.10.1529","volume":"40","author":"J Jankovic","year":"1990","unstructured":"Jankovic J, McDermott M, Carter J, Gauthier S, Goetz C, Golbe L, Huber S, Koller W, Olanow C, Shoulson I, Stern M, Tanner C, Weiner W, Parkinson Study G (1990) Variable expression of Parkinson\u2019s disease. Neurology 40(10):1529. https:\/\/doi.org\/10.1212\/WNL.40.10.1529","journal-title":"Neurology"},{"issue":"7","key":"6110_CR11","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1002\/mds.26657","volume":"31","author":"JG Nutt","year":"2016","unstructured":"Nutt JG (2016) Motor subtype in Parkinson\u2019s disease: different disorders or different stages of disease? Mov Disord 31(7):957\u2013961. https:\/\/doi.org\/10.1002\/mds.26657","journal-title":"Mov Disord"},{"key":"6110_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.601225","volume":"11","author":"J Ren","year":"2020","unstructured":"Ren J, Hua P, Li Y, Pan C, Yan L, Yu C, Zhang L, Xu P, Zhang M, Liu W (2020) Comparison of three motor subtype classifications in de novo Parkinson\u2019s disease patients. Front Neurol 11:601225. https:\/\/doi.org\/10.3389\/fneur.2020.601225","journal-title":"Front Neurol"},{"issue":"4","key":"6110_CR13","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1001\/jamaneurol.2018.4377","volume":"76","author":"E De Pablo-Fern\u00e1ndez","year":"2019","unstructured":"De Pablo-Fern\u00e1ndez E, Lees AJ, Holton JL, Warner TT (2019) Prognosis and neuropathologic correlation of clinical subtypes of Parkinson disease. JAMA Neurol 76(4):470\u2013479. https:\/\/doi.org\/10.1001\/jamaneurol.2018.4377","journal-title":"JAMA Neurol"},{"key":"6110_CR14","doi-asserted-by":"publisher","unstructured":"Rezvanian S, Lockhart T, Frames C, Soangra R, Lieberman A (2018) Motor subtypes of Parkinson\u2019s disease can be identified by frequency component of postural stability. Sensors (Basel) 18 (4). https:\/\/doi.org\/10.3390\/s18041102","DOI":"10.3390\/s18041102"},{"issue":"1","key":"6110_CR15","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.bbr.2008.11.020","volume":"199","author":"JA Grahn","year":"2009","unstructured":"Grahn JA, Parkinson JA, Owen AM (2009) The role of the basal ganglia in learning and memory: neuropsychological studies. Behav Brain Res 199(1):53\u201360. https:\/\/doi.org\/10.1016\/j.bbr.2008.11.020","journal-title":"Behav Brain Res"},{"key":"6110_CR16","doi-asserted-by":"publisher","unstructured":"Dickson DW (2018) Neuropathology of Parkinson disease. Parkinsonism Relat Disord 46 Suppl 1 (Suppl 1):S30-S33. https:\/\/doi.org\/10.1016\/j.parkreldis.2017.07.033","DOI":"10.1016\/j.parkreldis.2017.07.033"},{"key":"6110_CR17","doi-asserted-by":"publisher","first-page":"234","DOI":"10.3389\/fneur.2018.00234","volume":"9","author":"H Sanjari Moghaddam","year":"2018","unstructured":"Sanjari Moghaddam H, Ghazi Sherbaf F, Mojtahed Zadeh M, Ashraf-Ganjouei A, Aarabi MH (2018) Association between peripheral inflammation and DATSCAN data of the striatal nuclei in different motor subtypes of Parkinson disease. Front Neurol 9:234. https:\/\/doi.org\/10.3389\/fneur.2018.00234","journal-title":"Front Neurol"},{"issue":"1","key":"6110_CR18","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s00702-019-02122-9","volume":"127","author":"M L\u00f6hle","year":"2020","unstructured":"L\u00f6hle M, Wolz M, Beuthien-Baumann B, Oehme L, van den Hoff J, Kotzerke J, Reichmann H, Storch A (2020) Olfactory dysfunction correlates with putaminal dopamine turnover in early de novo Parkinson\u2019s disease. J Neural Transm (Vienna) 127(1):9\u201316. https:\/\/doi.org\/10.1007\/s00702-019-02122-9","journal-title":"J Neural Transm (Vienna)"},{"key":"6110_CR19","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.parkreldis.2018.06.022","volume":"56","author":"YS Oh","year":"2018","unstructured":"Oh YS, Kim JS, Hwang EJ, Lyoo CH (2018) Striatal dopamine uptake and olfactory dysfunction in patients with early Parkinson\u2019s disease. Parkinsonism Relat Disord 56:47\u201351. https:\/\/doi.org\/10.1016\/j.parkreldis.2018.06.022","journal-title":"Parkinsonism Relat Disord"},{"issue":"12","key":"6110_CR20","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1002\/mds.26424","volume":"30","author":"RB Postuma","year":"2015","unstructured":"Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G (2015) MDS clinical diagnostic criteria for Parkinson\u2019s disease. Mov Disord 30(12):1591\u20131601. https:\/\/doi.org\/10.1002\/mds.26424","journal-title":"Mov Disord"},{"key":"6110_CR21","doi-asserted-by":"publisher","unstructured":"Herman T, Weiss A, Brozgol M, Giladi N, Hausdorff JM (2014) Gait and balance in Parkinson\u2019s disease subtypes: objective measures and classification considerations. Journal of Neurology 2014 261:12 261 (12):2401\u20132410. https:\/\/doi.org\/10.1007\/S00415-014-7513-6","DOI":"10.1007\/S00415-014-7513-6"},{"issue":"5","key":"6110_CR22","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1002\/mds.25383","volume":"28","author":"GT Stebbins","year":"2013","unstructured":"Stebbins GT, Goetz CG, Burn DJ, Jankovic J, Khoo TK, Tilley BC (2013) How to identify tremor dominant and postural instability\/gait difficulty groups with the movement disorder society unified Parkinson\u2019s disease rating scale: comparison with the unified Parkinson\u2019s disease rating scale. Movement disorders\u202f: official journal of the Movement Disorder Society 28(5):668\u2013670. https:\/\/doi.org\/10.1002\/mds.25383","journal-title":"Movement disorders : official journal of the Movement Disorder Society"},{"issue":"9","key":"6110_CR23","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1002\/MDS.20513","volume":"20","author":"GA Kang","year":"2005","unstructured":"Kang GA, Bronstein JM, Masterman DL, Redelings M, Crum JA, Ritz B (2005) Clinical characteristics in early Parkinson\u2019s disease in a central California population-based study. Mov Disord 20(9):1133\u20131142. https:\/\/doi.org\/10.1002\/MDS.20513","journal-title":"Mov Disord"},{"issue":"supplement 2","key":"6110_CR24","first-page":"190","volume":"54","author":"J Seibyl","year":"2013","unstructured":"Seibyl J, Jennings D, Grachev I, Coffey C, Marek K (2013) 123-I ioflupane SPECT measures of Parkinson disease progression in the Parkinson Progression Marker Initiative (PPMI) trial. J Nucl Med 54(supplement 2):190","journal-title":"J Nucl Med"},{"issue":"3","key":"6110_CR25","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1002\/mds.26913","volume":"32","author":"AJ Espay","year":"2017","unstructured":"Espay AJ, Schwarzschild MA, Tanner CM, Fernandez HH, Simon DK, Leverenz JB, Merola A, Chen-Plotkin A, Brundin P, Kauffman MA, Erro R, Kieburtz K, Woo D, Macklin EA, Standaert DG, Lang AE (2017) Biomarker-driven phenotyping in Parkinson\u2019s disease: a translational missing link in disease-modifying clinical trials. Movement disorders\u202f: official journal of the Movement Disorder Society 32(3):319\u2013324. https:\/\/doi.org\/10.1002\/mds.26913","journal-title":"Movement disorders : official journal of the Movement Disorder Society"},{"issue":"2","key":"6110_CR26","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S1474-4422(10)70002-8","volume":"9","author":"CC Tang","year":"2010","unstructured":"Tang CC, Poston KL, Eckert T, Feigin A, Frucht S, Gudesblatt M, Dhawan V, Lesser M, Vonsattel J-P, Fahn S, Eidelberg D (2010) Differential diagnosis of parkinsonism: a metabolic imaging study using pattern analysis. Lancet Neurol 9(2):149\u2013158. https:\/\/doi.org\/10.1016\/S1474-4422(10)70002-8","journal-title":"Lancet Neurol"},{"issue":"10","key":"6110_CR27","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1001\/archneur.58.10.1611","volume":"58","author":"J Jankovic","year":"2001","unstructured":"Jankovic J, Kapadia AS (2001) Functional decline in Parkinson disease. Arch Neurol 58(10):1611\u20131615. https:\/\/doi.org\/10.1001\/archneur.58.10.1611","journal-title":"Arch Neurol"},{"key":"6110_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2021.117477","volume":"427","author":"B Balint","year":"2021","unstructured":"Balint B, Mulroy E, G\u00f6vert F, Latorre A, Di Lazarro G, Erro R, Batla A, Holton JL, Miki Y, Warner TT, Bhatia KP (2021) Development of parkinsonism after long-standing cervical dystonia - a cohort. J Neurol Sci 427:117477. https:\/\/doi.org\/10.1016\/j.jns.2021.117477","journal-title":"J Neurol Sci"},{"issue":"5","key":"6110_CR29","first-page":"395","volume":"41","author":"M Rudzi\u0144ska","year":"2007","unstructured":"Rudzi\u0144ska M, Marona M, Bukowczan S, Banaszkiewicz K, Mirek E, Szczudlik A (2007) Falls in different types of Parkinson\u2019s disease. Neurol Neurochir Pol 41(5):395\u2013403","journal-title":"Neurol Neurochir Pol"},{"issue":"5","key":"6110_CR30","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s12264-017-0170-x","volume":"33","author":"ME Fullard","year":"2017","unstructured":"Fullard ME, Morley JF, Duda JE (2017) Olfactory dysfunction as an early biomarker in Parkinson\u2019s disease. Neurosci Bull 33(5):515\u2013525","journal-title":"Neurosci Bull"},{"issue":"2","key":"6110_CR31","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0197-4580(02)00065-9","volume":"24","author":"H Braak","year":"2003","unstructured":"Braak H, Del Tredici K, R\u00fcb U, De Vos RA, Steur ENJ, Braak E (2003) Staging of brain pathology related to sporadic Parkinson\u2019s disease. Neurobiol Aging 24(2):197\u2013211","journal-title":"Neurobiol Aging"},{"issue":"2","key":"6110_CR32","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.parkreldis.2009.08.007","volume":"16","author":"CH Hawkes","year":"2010","unstructured":"Hawkes CH, Del Tredici K, Braak H (2010) A timeline for Parkinson\u2019s disease. Parkinsonism Relat Disord 16(2):79\u201384","journal-title":"Parkinsonism Relat Disord"},{"issue":"2","key":"6110_CR33","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s00401-008-0450-7","volume":"117","author":"TG Beach","year":"2009","unstructured":"Beach TG, White CL, Hladik CL, Sabbagh MN, Connor DJ, Shill HA, Sue LI, Sasse J, Bachalakuri J, Henry-Watson J (2009) Olfactory bulb \u03b1-synucleinopathy has high specificity and sensitivity for Lewy body disorders. Acta Neuropathol 117(2):169\u2013174","journal-title":"Acta Neuropathol"},{"issue":"4","key":"6110_CR34","first-page":"148","volume":"151","author":"N Modugno","year":"2013","unstructured":"Modugno N, Lena F, Di Biasio F, Cerrone G, Ruggieri S, Fornai F (2013) A clinical overview of non-motor symptoms in Parkinson\u2019s disease. Arch Ital Biol 151(4):148\u2013168","journal-title":"Arch Ital Biol"},{"key":"6110_CR35","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.parkreldis.2019.02.012","volume":"63","author":"Y-S Oh","year":"2019","unstructured":"Oh Y-S, Kim J-S, Yoo S-W, Hwang E-J, Lyoo CH, Lee K-S (2019) Striatal dopamine activity and myocardial 123I-metaiodobenzylguanidine uptake in early Parkinson\u2019s disease. Parkinsonism Relat Disord 63:156\u2013161","journal-title":"Parkinsonism Relat Disord"},{"issue":"10","key":"6110_CR36","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.1212\/01.WNL.0000161874.52302.5D","volume":"64","author":"A Siderowf","year":"2005","unstructured":"Siderowf A, Newberg A, Chou K, Lloyd M, Colcher A, Hurtig H, Stern M, Doty R, Mozley P, Wintering N (2005) [99mTc] TRODAT-1 SPECT imaging correlates with odor identification in early Parkinson disease. Neurology 64(10):1716\u20131720","journal-title":"Neurology"},{"issue":"1\u20132","key":"6110_CR37","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jns.2011.06.020","volume":"310","author":"HW Berendse","year":"2011","unstructured":"Berendse HW, Roos DS, Raijmakers P, Doty RL (2011) Motor and non-motor correlates of olfactory dysfunction in Parkinson\u2019s disease. J Neurol Sci 310(1\u20132):21\u201324","journal-title":"J Neurol Sci"},{"issue":"19","key":"6110_CR38","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1212\/WNL.0000000000000960","volume":"83","author":"D Jennings","year":"2014","unstructured":"Jennings D, Siderowf A, Stern M, Seibyl J, Eberly S, Oakes D, Marek K, Investigators P (2014) Imaging prodromal Parkinson disease: the Parkinson associated risk syndrome study. Neurology 83(19):1739\u20131746","journal-title":"Neurology"},{"key":"6110_CR39","unstructured":"Daalen JMJ, Tosserams A, Mahlknecht P, Seppi K, Bloem BR, Darweesh SK (2021) Towards subgroup-specific risk estimates: a meta-analysis of longitudinal studies on olfactory dysfunction and risk of Parkinson\u2019s disease. Parkinsonism & Related Disorders"},{"key":"6110_CR40","doi-asserted-by":"publisher","first-page":"471","DOI":"10.3389\/fneur.2019.00471","volume":"10","author":"JW Lee","year":"2019","unstructured":"Lee JW, Song YS, Kim H, Ku BD, Lee WW (2019) Alteration of tremor dominant and postural instability gait difficulty subtypes during the progression of Parkinson\u2019s disease: analysis of the PPMI cohort. Front Neurol 10:471. https:\/\/doi.org\/10.3389\/fneur.2019.00471","journal-title":"Front Neurol"},{"key":"6110_CR41","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-022-05952-w","author":"F Nabizadeh","year":"2022","unstructured":"Nabizadeh F, Pirahesh K, Khalili E (2022) Olfactory dysfunction is associated with motor function only in tremor-dominant Parkinson\u2019s disease. Neurol Sci. https:\/\/doi.org\/10.1007\/s10072-022-05952-w","journal-title":"Neurol Sci"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-022-06110-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-022-06110-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-022-06110-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T13:16:22Z","timestamp":1659532582000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-022-06110-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,4]]},"references-count":41,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["6110"],"URL":"https:\/\/doi.org\/10.1007\/s10072-022-06110-y","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,4]]},"assertion":[{"value":"3 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Since the data in this paper were obtained from the PPMI database (ppmi.loni.usc.edu), it does not include any research involving human or animal subjects.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This manuscript has been approved for publication by all authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}