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It was performed in accordance with the standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"We could not obtain written informed consent\u00a0from patients\u00a0to use clinical data because the study is population-based and observational retrospective.\u00a0Consent was waived thy the Ethics Committes.\u00a0Data was anonymized and did not contain variables that might identify individual patients. The study was conducted according to the Spanish law on the protection of personal data and the guarantee of digital rights (Organic Law 3\/2018 of December 5), and Regulation of the European Parliament and Council on the protection of people (EU 2016\/679 of April 27).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate and publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}