{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T12:36:18Z","timestamp":1763728578876,"version":"3.37.3"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1007\/s10072-023-07070-7","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T22:01:32Z","timestamp":1695938492000},"page":"1079-1086","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Validity, diagnostics and feasibility of the Italian version of the Montreal Cognitive Assessment (MoCA) in Huntington\u2019s disease"],"prefix":"10.1007","volume":"45","author":[{"given":"Edoardo Nicol\u00f2","family":"Aiello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Solca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Torre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annalisa","family":"Lafronza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Maranzano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruggero","family":"Bonetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Scheveger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Maffi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Consuelo","family":"Ceccarelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Scocchia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Casella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Verde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Migliore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Silani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Ticozzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando","family":"Squitieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Ciammola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4398-2051","authenticated-orcid":false,"given":"Barbara","family":"Poletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,28]]},"reference":[{"key":"7070_CR1","doi-asserted-by":"publisher","first-page":"e2395","DOI":"10.1212\/WNL.0000000000011893","volume":"96","author":"B McAllister","year":"2021","unstructured":"McAllister B, Gusella JF, Landwehrmeyer GB, Lee JM, MacDonald ME, Orth M et al (2021) Timing and impact of psychiatric, cognitive, and motor abnormalities in Huntington disease. Neurology 96:e2395\u2013e2406","journal-title":"Neurology"},{"key":"7070_CR2","doi-asserted-by":"publisher","first-page":"116523","DOI":"10.1016\/j.jns.2019.116523","volume":"408","author":"P Julayanont","year":"2020","unstructured":"Julayanont P, McFarland NR, Heilman KM (2020) Mild cognitive impairment and dementia in motor manifest Huntington\u2019s disease: classification and prevalence. J Neurol Sci 408:116523","journal-title":"J Neurol Sci"},{"key":"7070_CR3","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/B978-0-12-801893-4.00019-5","volume":"144","author":"JC Stout","year":"2017","unstructured":"Stout JC, Andrews SC, Glikmann-Johnston Y (2017) Cognitive assessment in Huntington disease clinical drug trials. Handb Clin Neurol 144:227\u2013244","journal-title":"Handb Clin Neurol"},{"key":"7070_CR4","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","volume":"53","author":"ZS Nasreddine","year":"2005","unstructured":"Nasreddine ZS, Phillips NA, B\u00e9dirian V, Charbonneau S, Whitehead V, Collin I et al (2005) The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc 53:695\u2013699","journal-title":"J Am Geriatr Soc"},{"key":"7070_CR5","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1002\/mds.27227","volume":"33","author":"TA Mestre","year":"2018","unstructured":"Mestre TA, Bachoud-L\u00e9vi AC, Marinus J, Stout JC, Paulsen JS, Como P et al (2018) Rating scales for cognition in Huntington\u2019s disease: Critique and recommendations. Mov Disord 33:187\u2013195","journal-title":"Mov Disord"},{"key":"7070_CR6","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1017\/S1092852920001868","volume":"27","author":"EC Rosca","year":"2020","unstructured":"Rosca EC, Simu M (2020) Montreal Cognitive Assessment for evaluating cognitive impairment in Huntington\u2019s disease: a systematic review. CNS Spectr 27:27\u201345","journal-title":"CNS Spectr"},{"key":"7070_CR7","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/978-3-319-44775-9_7","volume-title":"Cognitive Screening Instruments","author":"P Julayanont","year":"2017","unstructured":"Julayanont P, Nasreddine ZS (2017) Montreal Cognitive Assessment (MoCA): concept and clinical review. In: Larner AJ (ed) Cognitive Screening Instruments. Springer, pp 139\u2013195"},{"key":"7070_CR8","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1007\/s10072-021-05683-4","volume":"43","author":"EN Aiello","year":"2022","unstructured":"Aiello EN, Rimoldi S, Bolognini N, Appollonio I, Arcara G (2022) Psychometrics and diagnostics of Italian cognitive screening tests: a systematic review. Neurol Sci 43:821\u2013845","journal-title":"Neurol Sci"},{"key":"7070_CR9","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1002\/mds.26011","volume":"29","author":"R Reilmann","year":"2014","unstructured":"Reilmann R, Leavitt BR, Ross CA (2014) Diagnostic criteria for Huntington\u2019s disease based on natural history. Mov Disord 29:1335\u20131341","journal-title":"Mov Disord"},{"key":"7070_CR10","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1007\/s10072-014-1921-3","volume":"36","author":"S Conti","year":"2015","unstructured":"Conti S, Bonazzi S, Laiacona M, Masina M, Coralli MV (2015) Montreal Cognitive Assessment (MoCA)-Italian version: regression based norms and equivalent scores. Neurol Sci 36:209\u2013214","journal-title":"Neurol Sci"},{"key":"7070_CR11","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1002\/mds.26424","volume":"30","author":"RB Postuma","year":"2015","unstructured":"Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W et al (2015) MDS clinical diagnostic criteria for Parkinson\u2019s disease. Mov Disord 30:1591\u20131601","journal-title":"Mov Disord"},{"key":"7070_CR12","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1007\/s40520-021-01943-7","volume":"34","author":"EN Aiello","year":"2022","unstructured":"Aiello EN, Gramegna C, Esposito A, Gazzaniga V, Zago S, Difonzo T et al (2022) The Montreal Cognitive Assessment (MoCA): updated norms and psychometric insights into adaptive testing from healthy individuals in Northern Italy. Aging Clin Exp Res 34:375\u2013382","journal-title":"Aging Clin Exp Res"},{"key":"7070_CR13","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn","DOI":"10.1176\/appi.books.9780890425596"},{"key":"7070_CR14","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1002\/mds.870110204","volume":"11","author":"Huntington Study Group","year":"1996","unstructured":"Huntington Study Group (1996) Unified Huntington\u2019s Disease Rating Scale: reliability and consistency. Mov Disord 11:136\u2013142","journal-title":"Mov Disord"},{"key":"7070_CR15","first-page":"477","volume":"47","author":"G Novelli","year":"1986","unstructured":"Novelli G, Papagno C, Capitani E, Laiacona M, Cappa SF, Vallar G (1986) Tre test clinici di ricerca e produzione lessicale. Arch Psicol Neurol Psichiatr 47:477\u2013506","journal-title":"Arch Psicol Neurol Psichiatr"},{"key":"7070_CR16","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/BF00831566","volume":"19","author":"R Barbarotto","year":"1998","unstructured":"Barbarotto R, Laiacona M, Frosio R, Vecchio M, Farinato A, Capitani E (1998) A normative study on visual reaction times and two Stroop colour-word tests. Ital J Neurol Sci 19:161\u2013170","journal-title":"Ital J Neurol Sci"},{"key":"7070_CR17","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.jhep.2008.04.022","volume":"49","author":"P Amodio","year":"2008","unstructured":"Amodio P, Campagna F, Olianas S, Iannizzi P, Mapelli D, Penzo M et al (2008) Detection of minimal hepatic encephalopathy: normalization and optimization of the Psychometric Hepatic Encephalopathy Score. A neuropsychological and quantified EEG study. J Hepatol 49:346\u2013353","journal-title":"J Hepatol"},{"key":"7070_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1212\/WNL.29.1.1","volume":"29","author":"I Shoulson","year":"1979","unstructured":"Shoulson I, Fahn S (1979) Huntington disease: clinical care and evaluation. Neurology 29:1\u20131","journal-title":"Neurology"},{"key":"7070_CR19","first-page":"145","volume":"5","author":"CD Spielberger","year":"1971","unstructured":"Spielberger CD, Gonzalez-Reigosa F, Martinez-Urrutia A, Natalicio LF, Natalicio DS (1971) The state-trait anxiety inventory. Interam J Psychol 5:145\u2013158","journal-title":"Interam J Psychol"},{"key":"7070_CR20","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","volume":"4","author":"AT Beck","year":"1961","unstructured":"Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561\u2013571","journal-title":"Arch Gen Psychiatry"},{"key":"7070_CR21","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s10072-005-0443-4","volume":"26","author":"I Appollonio","year":"2005","unstructured":"Appollonio I, Leone M, Isella V, Piamarta F, Consoli T, Villa ML et al (2005) The Frontal Assessment Battery (FAB): normative values in an Italian population sample. Neurol Sci 26:108\u2013116","journal-title":"Neurol Sci"},{"key":"7070_CR22","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1080\/21678421.2016.1183679","volume":"17","author":"B Poletti","year":"2016","unstructured":"Poletti B, Solca F, Carelli L, Madotto F, Lafronza A, Faini A et al (2016) The validation of the Italian Edinburgh cognitive and behavioural ALS screen (ECAS). Amyotroph Lateral Scler Frontotemporal Degener 17:489\u2013498","journal-title":"Amyotroph Lateral Scler Frontotemporal Degener"},{"key":"7070_CR23","doi-asserted-by":"publisher","first-page":"4997","DOI":"10.1007\/s10072-021-05169-3","volume":"42","author":"L Carelli","year":"2021","unstructured":"Carelli L, Solca F, Migliore S, Torre S, Brugnera A, Mancini F et al (2021) Compensating for verbal-motor deficits in neuropsychological assessment in movement disorders: sensitivity and specificity of the ECAS in Parkinson\u2019s and Huntington\u2019s diseases. Neurol Sci 42:4997\u20135006","journal-title":"Neurol Sci"},{"key":"7070_CR24","first-page":"189","volume":"2","author":"A Basso","year":"1987","unstructured":"Basso A, Capitani E, Laiacona M (1987) Raven\u2019s coloured progressive matrices: normative values on 305 adult normal controls. Funct Neurol 2:189\u2013194","journal-title":"Funct Neurol"},{"key":"7070_CR25","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1159\/000117297","volume":"36","author":"GA Carlesimo","year":"1996","unstructured":"Carlesimo GA, Caltagirone C, Gainotti G, the MDB Group (1996) The Mental Deterioration Battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. Eur Neurol 36:378\u2013384","journal-title":"Eur Neurol"},{"key":"7070_CR26","volume-title":"Esame Neuropsicologico Breve 2 (ENB-2)","author":"S Mondini","year":"2003","unstructured":"Mondini S, Mapelli D, Vestri A, Arcara G, Bisiacchi P (2003) Esame Neuropsicologico Breve 2 (ENB-2). Raffaello Cortina Editore"},{"key":"7070_CR27","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1093\/arclin\/acab100","volume":"37","author":"O Maddaluno","year":"2022","unstructured":"Maddaluno O, Aiello EN, Roncoroni C, Prunas A, Bolognini N (2022) The reading the mind in the eyes test, Iowa gambling task and interpersonal reactivity index: normative data in an Italian population sample. Arch Clin Neuropsychol 37:929\u2013938","journal-title":"Arch Clin Neuropsychol"},{"key":"7070_CR28","unstructured":"Fahn S, Elton RL, UPDRS program members (1987) Unified Parkinson\u2019s disease rating scale. In: Fahn S, Marsden CD, Goldstein M, Calne DB (eds) Recent developments in Parkinson\u2019s disease, pp 153\u2013163"},{"key":"7070_CR29","unstructured":"Schwab RS, England AC (1969) Projection technique for evaluating surgery in Parkinson\u2019s disease. In: Gillingham FJ, Donaldson MC (eds) Third symposium on Parkinson\u2019s disease, pp 152\u2013157"},{"key":"7070_CR30","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1212\/WNL.40.10.1529","volume":"40","author":"J Jankovic","year":"1990","unstructured":"Jankovic J, McDermott M, Carter J, Gauthier S, Goetz C, Golbe L et al (1990) Variable expression of Parkinson\u2019s disease: a base-line analysis of the DAT ATOP cohort. Neurology 40:1529\u20131529","journal-title":"Neurology"},{"key":"7070_CR31","doi-asserted-by":"publisher","first-page":"52","DOI":"10.5395\/rde.2013.38.1.52","volume":"38","author":"HY Kim","year":"2013","unstructured":"Kim HY (2013) Statistical notes for clinical researchers: assessing normal distribution (2) using skewness and kurtosis. Restor Dent Endod 38:52\u201354","journal-title":"Restor Dent Endod"},{"key":"7070_CR32","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1002\/pnp.543","volume":"23","author":"AJ Larner","year":"2019","unstructured":"Larner AJ (2019) New unitary metrics for dementia test accuracy studies. Prog Neurol Psychiatry 23:21\u201325","journal-title":"Prog Neurol Psychiatry"},{"key":"7070_CR33","doi-asserted-by":"publisher","first-page":"1031871","DOI":"10.3389\/fpsyg.2022.1031871","volume":"13","author":"F Solca","year":"2022","unstructured":"Solca F, Aiello EN, Migliore S, Torre S, Carelli L, Ferrucci R et al (2022) Diagnostic properties of the Frontal Assessment Battery (FAB) in Huntington\u2019s disease. Front Psychol 13:1031871","journal-title":"Front Psychol"},{"key":"7070_CR34","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1176\/jnp.14.1.37","volume":"14","author":"JC Thompson","year":"2002","unstructured":"Thompson JC, Snowden JS, Craufurd D, Neary D (2002) Behavior in Huntington\u2019s disease: dissociating cognition-based and mood-based changes. J Neuropsychiatry Clin Neurosci 14:37\u201343","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"7070_CR35","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1007\/s10072-016-2807-3","volume":"38","author":"B Poletti","year":"2017","unstructured":"Poletti B, Carelli L, Solca F, Lafronza A, Pedroli E, Faini A et al (2017) An eye-tracking controlled neuropsychological battery for cognitive assessment in neurological diseases. Neurol Sci 38:595\u2013603","journal-title":"Neurol Sci"},{"key":"7070_CR36","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1007\/s00415-017-8506-z","volume":"264","author":"B Poletti","year":"2017","unstructured":"Poletti B, Carelli L, Solca F, Lafronza A, Pedroli E, Faini A et al (2017) An eye-tracker controlled cognitive battery: overcoming verbal-motor limitations in ALS. J Neurol 264:1136\u20131145","journal-title":"J Neurol"},{"key":"7070_CR37","doi-asserted-by":"publisher","first-page":"e0200953","DOI":"10.1371\/journal.pone.0200953","volume":"13","author":"B Poletti","year":"2018","unstructured":"Poletti B, Carelli L, Faini A, Solca F, Meriggi P, Lafronza A et al (2018) The Arrows and Colors Cognitive Test (ACCT): a new verbal-motor free cognitive measure for executive functions in ALS. Plos One 13:e0200953","journal-title":"Plos One"},{"key":"7070_CR38","doi-asserted-by":"publisher","first-page":"46","DOI":"10.3109\/00365513.2010.493383","volume":"70","author":"PM Bossuyt","year":"2010","unstructured":"Bossuyt PM (2010) Clinical validity: defining biomarker performance. Scand J Clin Lab Invest 70:46\u201352","journal-title":"Scand J Clin Lab Invest"},{"key":"7070_CR39","doi-asserted-by":"publisher","unstructured":"D\u2019Iorio A, Aiello EN, Amboni M, Vitale C, Verde F, Silani V et al (2023) Validity and diagnostics of the Italian version of the Montreal Cognitive Assessment (MoCA) in non-demented Parkinson\u2019s disease patients. Aging Clin Exp Res 1\u20137.  https:\/\/doi.org\/10.1007\/s40520-023-02493-w","DOI":"10.1007\/s40520-023-02493-w"},{"issue":"5","key":"7070_CR40","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1212\/WNL.41.5.634","volume":"41","author":"B Pillon","year":"1991","unstructured":"Pillon B, Dubois B, Ploska A, Agid Y (1991) Severity and specificity of cognitive impairment in Alzheimer\u2019s, Huntington\u2019s, and Parkinson\u2019s diseases and progressive supranuclear palsy. Neurology 41(5):634\u2013643","journal-title":"Neurology"},{"key":"7070_CR41","doi-asserted-by":"publisher","unstructured":"Aiello EN, D'Iorio A, Solca F, Torre S, Colombo E, Maranzano A et al (2023) Ecological validity of the Montreal Cognitive Assessment (MoCA) in non-demented Parkinson\u2019s disease patients. Neurodegener Dis 1\u20135. https:\/\/doi.org\/10.1159\/000532115","DOI":"10.1159\/000532115"},{"key":"7070_CR42","doi-asserted-by":"publisher","unstructured":"D\u2019Iorio A, Aiello EN, Trinchillo A, Silani V, Ticozzi N, Ciammola A et al (2023) Clinimetrics of the Italian version of the Montreal Cognitive Assessment (MoCA) in adult-onset idiopathic focal dystonia. J Neural Transm 1\u20138. https:\/\/doi.org\/10.1007\/s00702-023-02663-0","DOI":"10.1007\/s00702-023-02663-0"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-023-07070-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-023-07070-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-023-07070-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T02:03:43Z","timestamp":1707530623000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-023-07070-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,28]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["7070"],"URL":"https:\/\/doi.org\/10.1007\/s10072-023-07070-7","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"type":"print","value":"1590-1874"},{"type":"electronic","value":"1590-3478"}],"subject":[],"published":{"date-parts":[[2023,9,28]]},"assertion":[{"value":"5 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Participants provided informed consent. This study was approved by the Ethics Committee of IRCCS Istituto Auxologico Italiano (I.D.: 23C923_2019) and by the Institutional Review Board of LIRH Foundation (I.D.: 1.010721).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"V.S. received compensation for consulting services and\/or speaking activities from AveXis, Cytokinetics, Italfarmaco, Liquidweb S.r.l., Novartis Pharma AG and Zambon and receives or has received research supports from the Italian Ministry of Health, AriSLA, and E-Rare Joint Transnational Call. He is in the Editorial Board of <i>Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration<\/i>, <i>European Neurology<\/i>, <i>American Journal of Neurodegenerative Diseases<\/i>, <i>Frontiers in Neurology<\/i> and <i>Exploration of Neuroprotective Therapy<\/i>. B.P. received compensation for consulting services and\/or speaking activities from Liquidweb S.r.l. B.P. is Associated Editor for <i>Frontiers in Neuroscience<\/i>. N.T. received compensation for consulting services from Amylyx Pharmaceuticals and Zambon Biotech SA. He is Associate Editor for <i>Frontiers in Aging Neuroscience<\/i>. F.S. received compensation for consulting services and\/or speaking activities from La Hoffman-Roche, Novartis, PTC Therapeutics, Wave Life Science, Prilenia.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}