{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T12:17:47Z","timestamp":1754482667994,"version":"3.37.3"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:00:00Z","timestamp":1711497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:00:00Z","timestamp":1711497600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1007\/s10072-024-07488-7","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T06:40:15Z","timestamp":1711521615000},"page":"4341-4348","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Oromandibular dystonia: from onset to spread a multicenter italian study"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9413-3394","authenticated-orcid":false,"given":"Assunta","family":"Trinchillo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Terranova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Fabbrini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gina","family":"Ferrazzano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Belvisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Erro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Barone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Bono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Di Biasio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Rita","family":"Bentivoglio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Lettieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Concetta","family":"Altavista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesa Lorella Maria","family":"Scaglione","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Albanese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello Mario","family":"Mascia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Muroni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Pisani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Berardelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Defazio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,27]]},"reference":[{"key":"7488_CR1","first-page":"259","volume":"14","author":"CD Marsden","year":"1976","unstructured":"Marsden CD (1976) The problem of adult-onset idiopathic torsion dystonia and other isolated dyskinesias in adult life (including blepharospasm, oromandibular dystonia, dystonic writer\u2019s cramp, and torticollis, or axial dystonia). Adv Neurol 14:259\u2013276","journal-title":"Adv Neurol"},{"issue":"12","key":"7488_CR2","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1136\/jnnp.39.12.1204","volume":"39","author":"CD Marsden","year":"1976","unstructured":"Marsden CD (1976) Blepharospasm-oromandibular dystonia syndrome (Brueghel\u2019s syndrome). A variant of adult-onset torsion dystonia? J Neurol Neurosurg Psychiatry 39(12):1204\u201392","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"7488_CR3","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/2054-7072-1-3","volume":"1","author":"P Termsarasab","year":"2014","unstructured":"Termsarasab P, Tanenbaum DR, Frucht SJ (2014) The phenomenology and natural history of idiopathic lower cranial dystonia. J Clin Mov Disord 1:3","journal-title":"J Clin Mov Disord"},{"key":"7488_CR4","doi-asserted-by":"publisher","first-page":"583177","DOI":"10.3389\/fneur.2020.583177","volume":"11","author":"K Yoshida","year":"2020","unstructured":"Yoshida K (2020) Development and validation of a disease-specific oromandibular dystonia rating scale (OMDRS). Front Neurol 11:583177","journal-title":"Front Neurol"},{"key":"7488_CR5","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1002\/mds.25475","volume":"28","author":"A Albanese","year":"2013","unstructured":"Albanese A, Bhatia K, Bressman SB et al (2013) Phenomenology and classification of dystonia: a consensus update. Mov Disord 28:863\u2013873","journal-title":"Mov Disord"},{"key":"7488_CR6","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.clinph.2021.11.075","volume":"134","author":"N Manzo","year":"2022","unstructured":"Manzo N, Ginatempo F, Belvisi D, Defazio G, Conte A, Deriu F, Berardelli A (2022) Pathophysiological mechanisms of oromandibular dystonia. Clin Neurophysiol 134:73\u201380","journal-title":"Clin Neurophysiol"},{"key":"7488_CR7","doi-asserted-by":"publisher","first-page":"10359","DOI":"10.3389\/dyst.2022.10359","volume":"1","author":"LM Scorr","year":"2022","unstructured":"Scorr LM, Cho HJ, Kilic-Berkmen G, McKay JL et al (2022) Clinical features and evolution of blepharospasm: A multicenter international cohort and systematic literature review. Dystonia 1:10359","journal-title":"Dystonia"},{"issue":"3","key":"7488_CR8","doi-asserted-by":"publisher","first-page":"351","DOI":"10.4103\/aian.AIAN_906_20","volume":"24","author":"S Ray","year":"2021","unstructured":"Ray S, Kutty B, Pal PK, Yadav R (2021) Sleep and other non-motor symptoms in patients with idiopathic oromandibular dystonia and meige syndrome: A questionnaire-based study. Ann Indian Acad Neurol 24(3):351\u2013355","journal-title":"Ann Indian Acad Neurol"},{"issue":"13","key":"7488_CR9","doi-asserted-by":"publisher","first-page":"3","DOI":"10.5334\/tohm.730","volume":"30","author":"M Balal","year":"2023","unstructured":"Balal M, Demirkiran M (2023) Oromandibular Dystonia: Clinical and Demographic Data from Eight-Two Patients. Tremor Other Hyperkinet Mov (N Y) 30(13):3","journal-title":"Tremor Other Hyperkinet Mov (N Y)"},{"key":"7488_CR10","doi-asserted-by":"publisher","first-page":"2102","DOI":"10.1212\/WNL.53.9.2102","volume":"53","author":"EK Tan","year":"1999","unstructured":"Tan EK, Jankovic J (1999) Botulinum toxin A in patients with oromandibular dystonia: long-term follow-up. Neurology 53:2102\u20132107","journal-title":"Neurology"},{"issue":"10","key":"7488_CR11","doi-asserted-by":"publisher","first-page":"5755","DOI":"10.1007\/s00784-021-03878-9","volume":"25","author":"K Yoshida","year":"2021","unstructured":"Yoshida K (2021) Prevalence and incidence of oromandibular dystonia: an oral and maxillofacial surgery service-based study. Clin Oral Investig 25(10):5755\u20135764","journal-title":"Clin Oral Investig"},{"key":"7488_CR12","doi-asserted-by":"publisher","first-page":"78","DOI":"10.14802\/jmd.17065","volume":"11","author":"L Slaim","year":"2018","unstructured":"Slaim L, Cohen M, Klap P, Vidailhet M, Perrin A, Brasnu D et al (2018) Oromandibular dystonia: demographics and clinical data from 240 patients. J Mov Disord 11:78\u201381","journal-title":"J Mov Disord"},{"key":"7488_CR13","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1007\/s10072-017-2839-3","volume":"38","author":"G Defazio","year":"2017","unstructured":"Defazio G, Esposito M, Abbruzzese G et al (2017) The Italian Dystonia Registry: rationale, design, and preliminary findings. Neurol Sci 38:819\u2013825","journal-title":"Neurol Sci"},{"issue":"1","key":"7488_CR14","doi-asserted-by":"publisher","first-page":"26","DOI":"10.4103\/aian.aian_242_21","volume":"25","author":"U Saraf","year":"2022","unstructured":"Saraf U, Chandarana M, Divya KP, Krishnan S (2022) Oromandibular dystonia - a systematic review. Ann Indian Acad Neurol 25(1):26\u201334. https:\/\/doi.org\/10.4103\/aian.aian_242_21","journal-title":"Ann Indian Acad Neurol"},{"issue":"1\u20132","key":"7488_CR15","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.jns.2013.05.022","volume":"331","author":"MA Khooshnoodi","year":"2013","unstructured":"Khooshnoodi MA, Factor SA, Jinnah HA (2013) Secondary blepharospasm associated with structural lesions of the brain. J Neurol Sci 331(1\u20132):98\u2013101. https:\/\/doi.org\/10.1016\/j.jns.2013.05.022","journal-title":"J Neurol Sci"},{"issue":"9","key":"7488_CR16","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1007\/s10072-016-2598-6","volume":"37","author":"D Liuzzi","year":"2016","unstructured":"Liuzzi D, Gigante AF, Leo A, Defazio G (2016) The anatomical basis of upper limb dystonia: lesson from secondary cases. Neurol Sci 37(9):1393\u20131398","journal-title":"Neurol Sci"},{"key":"7488_CR17","doi-asserted-by":"publisher","first-page":"6483","DOI":"10.1007\/s00415-022-11310-9","volume":"269","author":"D Dressler","year":"2022","unstructured":"Dressler D, Altenm\u00fcller E, Giess R, Krauss JK, Adib SF (2022) The epidemiology of dystonia:the Hannover epidemiology study. J Neurol 269:6483\u20136493","journal-title":"J Neurol"},{"issue":"7","key":"7488_CR18","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1002\/mds.25567","volume":"28","author":"HA Jinnah","year":"2013","unstructured":"Jinnah HA, Berardelli A, Comella C, Defazio G, Delong MR, Factor S, Galpern WR, Hallett M, Ludlow CL, Perlmutter JS, Rosen AR, Dystonia Coalition Investigators (2013) The focal dystonias: current views and challenges for future research. Mov Disord 28(7):926\u201343. https:\/\/doi.org\/10.1002\/mds.25567","journal-title":"Mov Disord"},{"key":"7488_CR19","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/B978-0-12-819410-2.00011-4","volume":"184","author":"G Sciamanna","year":"2022","unstructured":"Sciamanna G, El Atiallah I, Montanari M et al (2022) Plasticity, genetics and epigenetics in dystonia: an update. Handb Clin Neurol 184:199\u2013206","journal-title":"Handb Clin Neurol"},{"issue":"9","key":"7488_CR20","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1101\/gad.259309.115","volume":"29","author":"Y Reizel","year":"2015","unstructured":"Reizel Y, Spiro A, Sabag O, Skversky Y, Hecht M, Keshet I, Berman BP, Cedar H (2015) Gender-specific postnatal demethylation and establishment of epigenetic memory. Genes Dev 29(9):923\u2013933. https:\/\/doi.org\/10.1101\/gad.259309.115","journal-title":"Genes Dev"},{"key":"7488_CR21","unstructured":"Klein C, Lohmann K, Marras C et al (2017) Hereditary dystonia overview. In: Adam MP, Feldman J, Mirzaa GM et al (eds) GeneReviews\u00ae [Internet]. University of Washington, Seattle, Seattle (WA), pp 1993\u20132024. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK1155\/"},{"key":"7488_CR22","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/bs.irn.2023.05.015","volume":"169","author":"D Martino","year":"2023","unstructured":"Martino D (2023) What can Epidemiological studies teach on the pathophysiology of adultonset isolated dystonia. Int Rev Neurobiol 169:21\u201360","journal-title":"Int Rev Neurobiol"},{"key":"7488_CR23","doi-asserted-by":"publisher","unstructured":"Velucci V, Idrissi S, Pellicciari R, Esposito M, Trinchillo A, Belvisi D, Fabbrini G, Ferrazzano G, Terranova C, Girlanda P, Majorana G, Rizzo V, Bono F, Idone G, Laterza V, Avanzino L, Di Biasio F, Marchese R, Castagna A, Ramella M, Lettieri C, Rinaldo S, Altavista MC, Polidori L, Bertolasi L, Tozzi MC, Erro R, Barone P, Barbero P, Ceravolo R, Mascia MM, Ercoli T, Muroni A, Artusi CA, Zibetti M, Scaglione CLM, Bentivoglio AR, Cotelli MS, Magistrelli L, Cossu G, Albanese A, Squintani GM, Schirinzi T, Gigante AF, Maderna L, Eleopra R, Pisani A, Cassano D, Romano M, Rizzo M, Berardelli A, Defazio G (2024) Italian Dystonia registry participants. Does sex influence the natural history of idiopathic adult-onset dystonia? J Neurol Neurosurg Psychiatry. https:\/\/doi.org\/10.1136\/jnnp-2023-332927","DOI":"10.1136\/jnnp-2023-332927"},{"issue":"4","key":"7488_CR24","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1002\/mds.28427","volume":"36","author":"A Latorre","year":"2021","unstructured":"Latorre A, Cocco A, Bhatia KP, Erro R, Antelmi E, Conte A, Rothwell JC, Rocchi L (2021) Defective somatosensory inhibition and plasticity are not required to develop dystonia. Mov Disord 36(4):1015\u20131021. https:\/\/doi.org\/10.1002\/mds.28427","journal-title":"Mov Disord"},{"key":"7488_CR25","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1136\/jnnp-2019-321794","volume":"91","author":"BD Berman","year":"2020","unstructured":"Berman BD, Groth CL, Sillau SH et al (2020) Risk of spread in adult-onset isolated focal dystonia: a prospective international cohort study. J Neurol Neurosurg Psychiatry 91:314\u2013320","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"11","key":"7488_CR26","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1002\/mds.25088","volume":"27","author":"D Martino","year":"2012","unstructured":"Martino D, Berardelli A, Abbruzzese G, Bentivoglio AR, Esposito M, Fabbrini G, Guidubaldi A, Girlanda P, Liguori R, Marinelli L, Morgante F, Santoro L, Defazio G (2012) Age at onset and symptom spread in primary adult-onset blepharospasm and cervical dystonia. Mov Disord 27(11):1447\u20131450. https:\/\/doi.org\/10.1002\/mds.25088","journal-title":"Mov Disord"},{"issue":"11","key":"7488_CR27","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1111\/ene.13731","volume":"25","author":"M Esposito","year":"2018","unstructured":"Esposito M, Fabbrini G, Ferrazzano G et al (2018) Spread of dystonia in patients with idiopathic adult-onset laryngeal dystonia. Eur J Neurol 25(11):1341\u20131344","journal-title":"Eur J Neurol"},{"key":"7488_CR28","doi-asserted-by":"publisher","unstructured":"Ercoli T, Erro R, Fabbrini G, Pellicciari R, Girlanda P, Terranova C, Avanzino L, Di Biasio F, Barone P, Esposito M, De Joanna G, Eleopra R, Bono F, Manzo L, Bentivoglio AR, Petracca M, Mascia MM, Albanese A, Castagna A, Ceravolo R, Altavista MC, Scaglione C, Magistrelli L, Zibetti M, Bertolasi L, Coletti Moja M, Cotelli MS, Cossu G, Minafra B, Pisani A, Misceo S, Modugno N, Romano M, Cassano D, Berardelli A, Defazio G (2021) Italian dystonia registry participants. Spread of segmental\/multifocal idiopathic adult-onset dystonia to a third body site. Parkinsonism Relat Disord 87:70\u201374. https:\/\/doi.org\/10.1016\/j.parkreldis.2021.04.022","DOI":"10.1016\/j.parkreldis.2021.04.022"},{"issue":"4","key":"7488_CR29","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1007\/s00415-019-09683-5","volume":"267","author":"E Sarasso","year":"2020","unstructured":"Sarasso E, Agosta F, Piramide N, Bianchi F, Butera C, Gatti R, Amadio S, Del Carro U, Filippi M (2020) Sensory trick phenomenon in cervical dystonia: a functional MRI study. J Neurol 267(4):1103\u20131115. https:\/\/doi.org\/10.1007\/s00415-019-09683-5","journal-title":"J Neurol"},{"key":"7488_CR30","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1002\/mds.25888","volume":"29","author":"S Amadio","year":"2014","unstructured":"Amadio S, Houdayer E, Bianchi F et al (2014) Sensory tricks and brain excitability in cervical dystonia: a transcranial magnetic stimulation study. Mov Disord 29:1185\u20131188","journal-title":"Mov Disord"},{"key":"7488_CR31","doi-asserted-by":"publisher","first-page":"103348","DOI":"10.1016\/j.nicl.2023.103348","volume":"37","author":"N Manzo","year":"2023","unstructured":"Manzo N, Leodori G, Ruocco G et al (2023) Cortical mechanisms of sensory trick in cervical dystonia. Neuroimage Clin 37:103348","journal-title":"Neuroimage Clin"},{"issue":"4","key":"7488_CR32","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1136\/jnnp.2007.124594","volume":"79","author":"G Abbruzzese","year":"2008","unstructured":"Abbruzzese G, Berardelli A, Girlanda P et al (2008) Long-term assessment of the risk of spread in primary late-onset focal dystonia. J Neurol Neurosurg Psychiatry 79(4):392\u20136","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-024-07488-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-024-07488-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-024-07488-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T10:29:10Z","timestamp":1723026550000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-024-07488-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,27]]},"references-count":32,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["7488"],"URL":"https:\/\/doi.org\/10.1007\/s10072-024-07488-7","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"type":"print","value":"1590-1874"},{"type":"electronic","value":"1590-3478"}],"subject":[],"published":{"date-parts":[[2024,3,27]]},"assertion":[{"value":"7 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"We confirm that we have read the Journal\u2019s position on issues involved in ethical publication and affirm that this work is consistent with those guidelines.Patients enrolled in the Italian Dystonia Registry signed the informed consent prior to their inclusion.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical compliance statement"}},{"value":"M.Z. received speaking honoraria from AbbVie, Bial, and Medtronic.No other specific funding was received for this work.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure"}},{"value":"The authors declare that there are no additional disclosures to report.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Financial disclosures"}},{"value":"The authors declare that there are no conflicts of interest relevant to this work.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}},{"value":"Informed Consent was given by all patients included in the register.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}