{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T10:04:24Z","timestamp":1783764264916,"version":"3.55.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T00:00:00Z","timestamp":1741219200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T00:00:00Z","timestamp":1741219200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071993, 81771914"],"award-info":[{"award-number":["82071993, 81771914"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Social Development Project of the Special Project for the Construction of Provincial TCM Rehabilitation Demonstration Center","award":["Y17kf02-4"],"award-info":[{"award-number":["Y17kf02-4"]}]},{"name":"Jiangsu Province Traditional Chinese Medicine Technology Development Plan Project","award":["YB201915"],"award-info":[{"award-number":["YB201915"]}]},{"name":"The seventh batch of national experts in traditional Chinese medicine academic experience inheritance work","award":["Guozhongyao Renjiao Han [2022] No. 76"],"award-info":[{"award-number":["Guozhongyao Renjiao Han [2022] No. 76"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>This study aimed to determine the repeatable effect of acupotomy on specific acupoints of paralyzed limbs in stroke patients with hemiplegia, using musculoskeletal ultrasound combined with acupuncture.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>102 patients with limb motor dysfunction post-cerebral stroke were randomly divided into two groups: the treatment group (T group) received ultrasound-guided acupotomy plus a basic treatment regimen (51 patients) and the control (C) group underwent the basic treatment regimen (51 patients) over 4 weeks, with a 6-month follow-up period. The T group was treated with ultrasound-guided acupotomy on the first day. Both groups received the same basic treatment. The primary outcome, the improvement in limb function, was evaluated using the Shangtianmin Hemiplegia Function Rating Scale score from baseline to 6 months. The secondary outcome measures included the neurological deficit scale, activities of daily living scale, modified Ashworth scale, and safety evaluation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The mean total Shangtianmin Hemiplegia Function rating scale score improved (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) after the first ultrasound-guided acupotomy treatment compared with baseline. After 6 months, the mean score of the upper limb in the T group was 8.86\u2009\u00b1\u20092.86, and in the C group, it was 6.08\u2009\u00b1\u20093.99 (difference, 2.78; 95% confidence interval, 1.42\u20134.15, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The mean score of the lower limb was 10.35\u2009\u00b1\u20091.80 in the T group and 6.86\u2009\u00b1\u20093.04 in the C group (difference, 3.49; 95% confidence interval, 2.51\u20134.47, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The function of the hemiplegic limb is significantly improved under ultrasound-guided acupotomy treatment combined with acupuncture.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Trial registration<\/jats:title>\n            <jats:p>Chinese Clinical Trials Register, ChiCTR1900028395, Registered 20 December 2019. <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.chictr.org.cn\/showproj.aspx?proj=47018\" ext-link-type=\"uri\">https:\/\/www.chictr.org.cn\/showproj.aspx?proj=47018<\/jats:ext-link>. Approved no. of the ethics committee: 2019NL-169-02.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s10072-025-08072-3","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T05:26:01Z","timestamp":1741238761000},"page":"2707-2716","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effect of ultrasound-guided acupotomy combined with acupuncture on limb dysfunction in patients with cerebral stroke"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3817-2362","authenticated-orcid":false,"given":"Xiao-Liang","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun-Xiang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Xiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Qi","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Ye","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Hao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Hua","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Bing","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Jun","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,6]]},"reference":[{"issue":"21","key":"8072_CR1","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1001\/jama.2019.6560","volume":"4","author":"MS Ekker","year":"2019","unstructured":"Ekker MS, Verhoeven JI, Vaartjes I, Jolink WMT, Klijn CJM, de Leeuw FE (2019 Jun 4) Association of stroke among adults aged 18 to 49 years with Long-term mortality. 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Specifically, no financial or non-financial conflicts of interest exist that could potentially influence the results or interpretation of the work presented in this manuscript. The research was conducted independently, without any undue influence from external entities.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study was approved by the Ethics Committee (National Chinese Medicine Clinical Trial Research Center (Nanjing)) of Affiliated Hospital of Nanjing University of Chinese Medicine (2019NL-169-02). All patients provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}]}}