{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T15:27:26Z","timestamp":1785338846309,"version":"3.55.0"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T00:00:00Z","timestamp":1766793600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T00:00:00Z","timestamp":1766793600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s10072-025-08713-7","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T05:43:08Z","timestamp":1766814188000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Headache in the elderly: a retrospective study in a tertiary headache center"],"prefix":"10.1007","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7760-9442","authenticated-orcid":false,"given":"Giulia","family":"Paparella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Scannicchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2103-4276","authenticated-orcid":false,"given":"Giulia","family":"Paparella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Di Dio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Abbatantuono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livio","family":"Clemente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna Diletta","family":"Delussi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6567-5373","authenticated-orcid":false,"given":"Marina","family":"de Tommaso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,27]]},"reference":[{"key":"8713_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/0333102417738202","volume":"38","author":"Headache Classification Committee of the International Headache Society (IHS)","year":"2018","unstructured":"Headache Classification Committee of the International Headache Society (IHS) (2018) The international classification of headache disorders, 3rd edition. Cephalalgia 38:1\u2013211. https:\/\/doi.org\/10.1177\/0333102417738202","journal-title":"Cephalalgia"},{"key":"8713_CR2","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1016\/S0140-6736(17)32154-2","volume":"390","author":"GBD 2016 Disease and Injury Incidence and Prevalence Collaborators","year":"2017","unstructured":"GBD 2016 Disease and Injury Incidence and Prevalence Collaborators (2017) Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990\u20132016: a systematic analysis for the global burden of disease study 2016. Lancet 390:1211\u20131259. https:\/\/doi.org\/10.1016\/S0140-6736(17)32154-2","journal-title":"Lancet"},{"key":"8713_CR3","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1016\/S0140-6736(20)32160-7","volume":"397","author":"M Ashina","year":"2021","unstructured":"Ashina M, Katsarava Z, Do TP et al (2021) Migraine: epidemiology and systems of care. Lancet 397:1485\u20131495. https:\/\/doi.org\/10.1016\/S0140-6736(20)32160-7","journal-title":"Lancet"},{"key":"8713_CR4","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s10194-022-01402-2","volume":"23","author":"LJ Stovner","year":"2022","unstructured":"Stovner LJ, Hagen K, Linde M, Steiner TJ (2022) The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates. J Headache Pain 23:34. https:\/\/doi.org\/10.1186\/s10194-022-01402-2","journal-title":"J Headache Pain"},{"key":"8713_CR5","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1016\/S1474-4422(23)00206-5","volume":"22","author":"SS Hugger","year":"2023","unstructured":"Hugger SS, Do TP, Ashina H et al (2023) Migraine in older adults. Lancet Neurol 22:934\u2013945. https:\/\/doi.org\/10.1016\/S1474-4422(23)00206-5","journal-title":"Lancet Neurol"},{"key":"8713_CR6","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1212\/01.wnl.0000172918.74999.8a","volume":"65","author":"AC Lyngberg","year":"2005","unstructured":"Lyngberg AC, Rasmussen BK, J\u00f8rgensen T, Jensen R (2005) Prognosis of migraine and tension-type headache: a population-based follow-up study. Neurology 65:580\u2013585. https:\/\/doi.org\/10.1212\/01.wnl.0000172918.74999.8a","journal-title":"Neurology"},{"key":"8713_CR7","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1111\/j.1526-4610.2006.00343.x","volume":"46","author":"KM Martins","year":"2006","unstructured":"Martins KM, Bordini CA, Bigal ME, Speciali JG (2006) Migraine in the elderly: a comparison with migraine in young adults. Headache 46:312\u2013316. https:\/\/doi.org\/10.1111\/j.1526-4610.2006.00343.x","journal-title":"Headache"},{"key":"8713_CR8","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1046\/j.1468-2982.1997.1704488.x","volume":"17","author":"B Bille","year":"1997","unstructured":"Bille B (1997) A 40-year follow-up of school children with migraine. Cephalalgia 17:488\u2013491 discussion 487. https:\/\/doi.org\/10.1046\/j.1468-2982.1997.1704488.x","journal-title":"Cephalalgia"},{"key":"8713_CR9","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/j.1533-2500.2009.00305.x","volume":"9","author":"YY Beckmann","year":"2009","unstructured":"Beckmann YY, Se\u00e7il Y, Kendir AI, Ba\u015fo\u011flu M (2009) Chronic migraine: a prospective descriptive clinical study in a headache center population. Pain Pract 9:380\u2013384. https:\/\/doi.org\/10.1111\/j.1533-2500.2009.00305.x","journal-title":"Pain Pract"},{"key":"8713_CR10","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1007\/s11916-022-01029-7","volume":"26","author":"N Riggins","year":"2022","unstructured":"Riggins N, Ehrlich A (2022) Episodic migraine and older adults. Curr Pain Headache Rep 26:331\u2013335. https:\/\/doi.org\/10.1007\/s11916-022-01029-7","journal-title":"Curr Pain Headache Rep"},{"key":"8713_CR11","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1212\/01.wnl.0000225186.76323.69","volume":"67","author":"ME Bigal","year":"2006","unstructured":"Bigal ME, Liberman JN, Lipton RB (2006) Age-dependent prevalence and clinical features of migraine. Neurology 67:246\u2013251. https:\/\/doi.org\/10.1212\/01.wnl.0000225186.76323.69","journal-title":"Neurology"},{"key":"8713_CR12","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1136\/jnnp.70.3.377","volume":"70","author":"M Prencipe","year":"2001","unstructured":"Prencipe M, Casini AR, Ferretti C et al (2001) Prevalence of headache in an elderly population: attack frequency, disability, and use of medication. J Neurol Neurosurg Psychiatry 70:377\u2013381. https:\/\/doi.org\/10.1136\/jnnp.70.3.377","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"8713_CR13","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1111\/j.1526-4610.2008.01117_1.x","volume":"48","author":"SJ Tepper","year":"2008","unstructured":"Tepper SJ (2008) A pivotal moment in 50 years of headache history: the first American migraine study. Headache 48:730\u2013731 discussion 732. https:\/\/doi.org\/10.1111\/j.1526-4610.2008.01117_1.x","journal-title":"Headache"},{"key":"8713_CR14","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1111\/j.1526-4610.2009.01502.x","volume":"49","author":"CGH Dahl\u00f6f","year":"2009","unstructured":"Dahl\u00f6f CGH, Johansson M, Casserstedt S, Motallebzadeh T (2009) The course of frequent episodic migraine in a large headache clinic population: a 12-year retrospective follow-up study. Headache 49:1144\u20131152. https:\/\/doi.org\/10.1111\/j.1526-4610.2009.01502.x","journal-title":"Headache"},{"key":"8713_CR15","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s10194-016-0672-3","volume":"17","author":"Y Zhang","year":"2016","unstructured":"Zhang Y, Shi Z, Hock D et al (2016) Prevalence of primary headache disorders in a population aged 60 years and older in a rural area of Northern China. J Headache Pain 17:83. https:\/\/doi.org\/10.1186\/s10194-016-0672-3","journal-title":"J Headache Pain"},{"key":"8713_CR16","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1111\/head.13247","volume":"58","author":"P de Rijk","year":"2018","unstructured":"de Rijk P, Resseguier N, Donnet A (2018) Headache characteristics and clinical features of elderly migraine patients. Headache 58:525\u2013533. https:\/\/doi.org\/10.1111\/head.13247","journal-title":"Headache"},{"key":"8713_CR17","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1186\/s12877-022-03027-1","volume":"22","author":"M Togha","year":"2022","unstructured":"Togha M, Karimitafti MJ, Ghorbani Z et al (2022) Characteristics and comorbidities of headache in patients over 50 years of age: a cross-sectional study. BMC Geriatr 22:313. https:\/\/doi.org\/10.1186\/s12877-022-03027-1","journal-title":"BMC Geriatr"},{"key":"8713_CR18","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1111\/j.1526-4610.2006.00444.x","volume":"46","author":"L Kelman","year":"2006","unstructured":"Kelman L (2006) Migraine changes with age: IMPACT on migraine classification. Headache 46:1161\u20131171. https:\/\/doi.org\/10.1111\/j.1526-4610.2006.00444.x","journal-title":"Headache"},{"key":"8713_CR19","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/s10194-021-01327-2","volume":"22","author":"M Delussi","year":"2021","unstructured":"Delussi M, Laporta A, Fraccalvieri I, de Tommaso M (2021) Osmophobia in primary headache patients: associated symptoms and response to preventive treatments. J Headache Pain 22:109. https:\/\/doi.org\/10.1186\/s10194-021-01327-2","journal-title":"J Headache Pain"},{"key":"8713_CR20","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1186\/s12883-020-01839-5","volume":"20","author":"M Delussi","year":"2020","unstructured":"Delussi M, Vecchio E, Libro G et al (2020) Failure of preventive treatments in migraine: an observational retrospective study in a tertiary headache center. BMC Neurol 20:256. https:\/\/doi.org\/10.1186\/s12883-020-01839-5","journal-title":"BMC Neurol"},{"key":"8713_CR21","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1046\/j.0333-1024.2001.00277.x","volume":"21","author":"D D\u2019Amico","year":"2001","unstructured":"D\u2019Amico D, Mosconi P, Genco S et al (2001) The migraine disability assessment (MIDAS) questionnaire: translation and reliability of the Italian version. Cephalalgia 21:947\u2013952. https:\/\/doi.org\/10.1046\/j.0333-1024.2001.00277.x","journal-title":"Cephalalgia"},{"key":"8713_CR22","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1159\/000499764","volume":"81","author":"M de Tommaso","year":"2019","unstructured":"de Tommaso M, Brighina F, Delussi M (2019) Effects of botulinum toxin A on allodynia in chronic migraine: an observational open-label two-year study. Eur Neurol 81:37\u201346. https:\/\/doi.org\/10.1159\/000499764","journal-title":"Eur Neurol"},{"key":"8713_CR23","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/B978-0-12-823357-3.00010-0","volume":"199","author":"PA Olson","year":"2024","unstructured":"Olson PA, Smith JH, Haan J (2024) Special considerations in management of migraine in the elderly. Handb Clin Neurol 199:265\u2013275. https:\/\/doi.org\/10.1016\/B978-0-12-823357-3.00010-0","journal-title":"Handb Clin Neurol"},{"key":"8713_CR24","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1159\/000494758","volume":"52","author":"T Wijeratne","year":"2019","unstructured":"Wijeratne T, Tang HM, Crewther D, Crewther S (2019) Prevalence of migraine in the elderly: a narrated review. Neuroepidemiology 52:104\u2013110. https:\/\/doi.org\/10.1159\/000494758","journal-title":"Neuroepidemiology"},{"key":"8713_CR25","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/j.1468-2982.2006.01250.x","volume":"27","author":"J Haan","year":"2007","unstructured":"Haan J, Hollander J, Ferrari MD (2007) Migraine in the elderly: a review. Cephalalgia 27:97\u2013106. https:\/\/doi.org\/10.1111\/j.1468-2982.2006.01250.x","journal-title":"Cephalalgia"},{"key":"8713_CR26","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1001\/jama.1992.03480010072027","volume":"267","author":"WF Stewart","year":"1992","unstructured":"Stewart WF, Lipton RB, Celentano DD, Reed ML (1992) Prevalence of migraine headache in the United States. Relation to age, income, race, and other sociodemographic factors. JAMA 267:64\u201369","journal-title":"JAMA"},{"key":"8713_CR27","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1186\/s10194-022-01447-3","volume":"23","author":"R Ruscheweyh","year":"2022","unstructured":"Ruscheweyh R, Klonowski T, Go\u00dfrau G et al (2022) The headache registry of the German migraine and headache society (DMKG): baseline data of the first 1,351 patients. J Headache Pain 23:74. https:\/\/doi.org\/10.1186\/s10194-022-01447-3","journal-title":"J Headache Pain"},{"key":"8713_CR28","doi-asserted-by":"publisher","first-page":"S120","DOI":"10.1192\/bjo.2021.349","volume":"7","author":"MS Inam","year":"2021","unstructured":"Inam MS, Nahar S, Miah MZ (2021) Hypnic headache: a rare type of primary headache disorder. BJPsych Open 7:S120\u2013S120. https:\/\/doi.org\/10.1192\/bjo.2021.349","journal-title":"BJPsych Open"},{"key":"8713_CR29","first-page":"45","volume":"2","author":"WPJ van Oosterhout","year":"2016","unstructured":"van Oosterhout WPJ, Cheung C, Haan J (2016) Primary headache syndromes in the elderly: epidemiology, diagnosis and treatment. J Clin Transl Res 2:45\u201351","journal-title":"J Clin Transl Res"},{"key":"8713_CR30","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1111\/j.1468-2982.2004.00729.x","volume":"24","author":"C Lisotto","year":"2004","unstructured":"Lisotto C, Mainardi F, Maggioni F, Zanchin G (2004) Episodic hypnic headache? Cephalalgia 24:681\u2013685. https:\/\/doi.org\/10.1111\/j.1468-2982.2004.00729.x","journal-title":"Cephalalgia"},{"key":"8713_CR31","doi-asserted-by":"publisher","first-page":"333102423120157","DOI":"10.1177\/03331024231201577","volume":"43","author":"SA Kim","year":"2023","unstructured":"Kim SA, Choi SY, Youn MS et al (2023) Epidemiology, burden and clinical spectrum of cluster headache: a global update. Cephalalgia 43:3331024231201577. https:\/\/doi.org\/10.1177\/03331024231201577","journal-title":"Cephalalgia"},{"key":"8713_CR32","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1007\/s11916-009-0076-z","volume":"13","author":"SC Crystal","year":"2009","unstructured":"Crystal SC, Grosberg BM (2009) Tension-type headache in the elderly. Curr Pain Headache Rep 13:474\u2013478. https:\/\/doi.org\/10.1007\/s11916-009-0076-z","journal-title":"Curr Pain Headache Rep"},{"key":"8713_CR33","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/s10654-004-6519-2","volume":"20","author":"AC Lyngberg","year":"2005","unstructured":"Lyngberg AC, Rasmussen BK, J\u00f8rgensen T, Jensen R (2005) Has the prevalence of migraine and tension-type headache changed over a 12-year period? A Danish population survey. Eur J Epidemiol 20:243\u2013249. https:\/\/doi.org\/10.1007\/s10654-004-6519-2","journal-title":"Eur J Epidemiol"},{"key":"8713_CR34","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1111\/head.13067","volume":"58","author":"RH Jensen","year":"2018","unstructured":"Jensen RH (2018) Tension-type headache - the normal and most prevalent headache. Headache 58:339\u2013345. https:\/\/doi.org\/10.1111\/head.13067","journal-title":"Headache"},{"key":"8713_CR35","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1212\/WNL.0000000000006697","volume":"92","author":"TP Do","year":"2019","unstructured":"Do TP, Remmers A, Schytz HW et al (2019) Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list. Neurology 92:134\u2013144. https:\/\/doi.org\/10.1212\/WNL.0000000000006697","journal-title":"Neurology"},{"key":"8713_CR36","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1111\/j.1526-4610.2011.01883.x","volume":"51","author":"F Radat","year":"2011","unstructured":"Radat F, Milowska D, Valade D (2011) Headaches secondary to psychiatric disorders (HSPD): a retrospective study of 87 patients. Headache 51:789\u2013795. https:\/\/doi.org\/10.1111\/j.1526-4610.2011.01883.x","journal-title":"Headache"},{"key":"8713_CR37","doi-asserted-by":"publisher","unstructured":"American Psychiatric Association, DSM-5 Task Force (2013) Diagnostic and statistical manual of mental disorders: DSM-5\u2122, 5th ed. American Psychiatric Publishing, Inc., Arlington, VA, US. https:\/\/doi.org\/10.1176\/appi.books.9780890425596","DOI":"10.1176\/appi.books.9780890425596"},{"key":"8713_CR38","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1093\/aje\/kwi139","volume":"161","author":"AC Lyngberg","year":"2005","unstructured":"Lyngberg AC, Rasmussen BK, J\u00f8rgensen T, Jensen R (2005) Incidence of primary headache: a Danish epidemiologic follow-up study. Am J Epidemiol 161:1066\u20131073. https:\/\/doi.org\/10.1093\/aje\/kwi139","journal-title":"Am J Epidemiol"},{"key":"8713_CR39","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1111\/j.1468-2982.2008.01666.x","volume":"28","author":"WF Stewart","year":"2008","unstructured":"Stewart WF, Wood C, Reed ML et al (2008) Cumulative lifetime migraine incidence in women and men. Cephalalgia 28:1170\u20131178. https:\/\/doi.org\/10.1111\/j.1468-2982.2008.01666.x","journal-title":"Cephalalgia"},{"key":"8713_CR40","doi-asserted-by":"publisher","first-page":"333102424129945","DOI":"10.1177\/03331024241299453","volume":"44","author":"G Dalla Volta","year":"2024","unstructured":"Dalla Volta G, Russo A, Silvestro M et al (2024) Exploring the multifaceted characteristics of aura in migraine: a multicenter, cross-sectional study. Cephalalgia 44:3331024241299453. https:\/\/doi.org\/10.1177\/03331024241299453","journal-title":"Cephalalgia"},{"key":"8713_CR41","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1177\/0333102415597527","volume":"36","author":"M de Tommaso","year":"2016","unstructured":"de Tommaso M, Sciruicchio V, Ricci K et al (2016) Laser-evoked potential habituation and central sensitization symptoms in childhood migraine. Cephalalgia 36:463\u2013473. https:\/\/doi.org\/10.1177\/0333102415597527","journal-title":"Cephalalgia"},{"key":"8713_CR42","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1002\/ejp.1010","volume":"21","author":"M de Tommaso","year":"2017","unstructured":"de Tommaso M, Ricci K, Montemurno A, Vecchio E (2017) Age-related changes in laser-evoked potentials following trigeminal and hand stimulation in healthy subjects. Eur J Pain 21:1087\u20131097. https:\/\/doi.org\/10.1002\/ejp.1010","journal-title":"Eur J Pain"},{"key":"8713_CR43","doi-asserted-by":"publisher","first-page":"3489","DOI":"10.1093\/brain\/awt251","volume":"136","author":"MA Louter","year":"2013","unstructured":"Louter MA, Bosker JE, van Oosterhout WPJ et al (2013) Cutaneous allodynia as a predictor of migraine chronification. Brain 136:3489\u20133496. https:\/\/doi.org\/10.1093\/brain\/awt251","journal-title":"Brain"},{"key":"8713_CR44","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/s12883-018-1098-0","volume":"18","author":"M de Tommaso","year":"2018","unstructured":"de Tommaso M, Delussi M (2018) Circadian rhythms of migraine attacks in episodic and chronic patients: a cross sectional study in a headache center population. BMC Neurol 18:94. https:\/\/doi.org\/10.1186\/s12883-018-1098-0","journal-title":"BMC Neurol"},{"key":"8713_CR45","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4616417","volume":"2019","author":"D Baksa","year":"2019","unstructured":"Baksa D, Gecse K, Kumar S et al (2019) Circadian variation of migraine attack onset: a review of clinical studies. Biomed Res Int 2019:4616417. https:\/\/doi.org\/10.1155\/2019\/4616417","journal-title":"Biomed Res Int"},{"key":"8713_CR46","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1212\/WNL.0b013e3182a6cb32","volume":"81","author":"A Bashir","year":"2013","unstructured":"Bashir A, Lipton RB, Ashina S, Ashina M (2013) Migraine and structural changes in the brain: a systematic review and meta-analysis. Neurology 81:1260\u20131268. https:\/\/doi.org\/10.1212\/WNL.0b013e3182a6cb32","journal-title":"Neurology"},{"key":"8713_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2023.103312","volume":"37","author":"W Zhang","year":"2023","unstructured":"Zhang W, Cheng Z, Fu F, Zhan Z (2023) Prevalence and clinical characteristics of white matter hyperintensities in migraine: a meta-analysis. Neuroimage Clin 37:103312. https:\/\/doi.org\/10.1016\/j.nicl.2023.103312","journal-title":"Neuroimage Clin"},{"key":"8713_CR48","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1136\/jnnp.70.1.2","volume":"70","author":"JM Wardlaw","year":"2001","unstructured":"Wardlaw JM (2001) Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study: the Rotterdam scan study. J Neurol Neurosurg Psychiatry 70:2\u20133. https:\/\/doi.org\/10.1136\/jnnp.70.1.2","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"8713_CR49","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s10194-024-01770-x","volume":"25","author":"PT Tran","year":"2024","unstructured":"Tran PT, Lapeyre-Mestre M, Berangere B et al (2024) Triptan use in elderly over 65 years and the risk of hospitalization for serious vascular events. J Headache Pain 25:68. https:\/\/doi.org\/10.1186\/s10194-024-01770-x","journal-title":"J Headache Pain"},{"key":"8713_CR50","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1186\/s12889-024-21244-8","volume":"25","author":"G Coppola","year":"2025","unstructured":"Coppola G, Brown JD, Mercadante AR et al (2025) The epidemiology and unmet need of migraine in five European countries: results from the National health and wellness survey. BMC Public Health 25:254. https:\/\/doi.org\/10.1186\/s12889-024-21244-8","journal-title":"BMC Public Health"},{"key":"8713_CR51","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1007\/s00415-022-11457-5","volume":"270","author":"C Altamura","year":"2023","unstructured":"Altamura C, Ornello R, Ahmed F et al (2023) OnabotulinumtoxinA in elderly patients with chronic migraine: insights from a real-life European multicenter study. J Neurol 270:986\u2013994. https:\/\/doi.org\/10.1007\/s00415-022-11457-5","journal-title":"J Neurol"},{"key":"8713_CR52","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/S0304-3959(99)00057-3","volume":"82","author":"S-J Wang","year":"1999","unstructured":"Wang S-J, Liu H-C, Fuh J-L et al (1999) Comorbidity of headaches and depression in the elderly. Pain 82:239\u2013243. https:\/\/doi.org\/10.1016\/S0304-3959(99)00057-3","journal-title":"Pain"},{"key":"8713_CR53","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1046\/j.1468-2982.2002.00407.x","volume":"22","author":"P Mattsson","year":"2002","unstructured":"Mattsson P, Ekselius L (2002) Migraine, major depression, panic disorder, and personality traits in women aged 40\u201374 years: a population-based study. Cephalalgia 22:543\u2013551. https:\/\/doi.org\/10.1046\/j.1468-2982.2002.00407.x","journal-title":"Cephalalgia"},{"key":"8713_CR54","doi-asserted-by":"publisher","first-page":"4818","DOI":"10.1038\/s41598-025-88961-x","volume":"15","author":"T Hu","year":"2025","unstructured":"Hu T, Wang F, Duan Q et al (2025) Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis. Sci Rep 15:4818. https:\/\/doi.org\/10.1038\/s41598-025-88961-x","journal-title":"Sci Rep"},{"key":"8713_CR55","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.jocn.2018.01.032","volume":"50","author":"J-G Seo","year":"2018","unstructured":"Seo J-G, Park S-P (2018) Significance of fatigue in patients with migraine. J Clin Neurosci 50:69\u201373. https:\/\/doi.org\/10.1016\/j.jocn.2018.01.032","journal-title":"J Clin Neurosci"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-025-08713-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-025-08713-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-025-08713-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T08:12:09Z","timestamp":1770797529000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-025-08713-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,27]]},"references-count":55,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["8713"],"URL":"https:\/\/doi.org\/10.1007\/s10072-025-08713-7","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,27]]},"assertion":[{"value":"29 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of University of Bari.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"55"}}