{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T03:27:16Z","timestamp":1786591636294,"version":"build-2736575974"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Capital\u2019s Funds for Health Improvement and Research","award":["2026-2-20113"],"award-info":[{"award-number":["2026-2-20113"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol Sci"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s10072-026-09264-1","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T02:29:25Z","timestamp":1785119365000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["E200K genetic Creutzfeldt\u2013Jakob disease with codon 129 MV heterozygosity presenting with a V2-like phenotype: a case report"],"prefix":"10.1007","volume":"47","author":[{"given":"Rui","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6708-8391","authenticated-orcid":false,"given":"Zhongyun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"issue":"2","key":"9264_CR1","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1002\/1531-8249(199908)46:2<224::AID-ANA12>3.0.CO;2-W","volume":"46","author":"P Parchi","year":"1999","unstructured":"Parchi P, Giese A, Capellari S et al (1999) Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Ann Neurol 46(2):224\u2013233","journal-title":"Ann Neurol"},{"issue":"1","key":"9264_CR2","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s00401-010-0760-4","volume":"121","author":"S Capellari","year":"2011","unstructured":"Capellari S, Strammiello R, Saverioni D et al (2011) Genetic Creutzfeldt-Jakob disease and fatal familial insomnia: insights into phenotypic variability and disease pathogenesis. Acta Neuropathol 121(1):21\u201337","journal-title":"Acta Neuropathol"},{"issue":"1","key":"9264_CR3","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1007\/s00401-025-02903-5","volume":"149","author":"MA Barria","year":"2025","unstructured":"Barria MA, Soto P, Gonzalez-Romero D et al (2025) Characterization of prion strains and peripheral prion infectivity patterns in E200K genetic CJD patients. Acta Neuropathol 149(1):62","journal-title":"Acta Neuropathol"},{"issue":"4","key":"9264_CR4","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1007\/s00401-021-02350-y","volume":"142","author":"S Baiardi","year":"2021","unstructured":"Baiardi S, Rossi M, Mammana A et al (2021) Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification. Acta Neuropathol 142(4):707\u2013728","journal-title":"Acta Neuropathol"},{"key":"9264_CR5","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12939","author":"V Venkatraghavan","year":"2023","unstructured":"Venkatraghavan V, Pascuzzo R, Bron EE et al (2023) A discriminative event-based model for subtype diagnosis of sporadic Creutzfeldt-Jakob disease using brain MRI. Alzheimers Dement. https:\/\/doi.org\/10.1002\/alz.12939","journal-title":"Alzheimers Dement"},{"issue":"2","key":"9264_CR6","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s00401-020-02168-0","volume":"140","author":"R Pascuzzo","year":"2020","unstructured":"Pascuzzo R, Oxtoby NP, Young AL et al (2020) Prion propagation estimated from brain diffusion MRI is subtype dependent in sporadic Creutzfeldt-Jakob disease. Acta Neuropathol 140(2):169\u2013181","journal-title":"Acta Neuropathol"},{"key":"9264_CR7","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s00401-024-02738-6","volume":"147","author":"H Kishida","year":"2024","unstructured":"Kishida H, Kobayashi A, Teruya K et al (2024) Transmission experiments verify sporadic V2 prion in a patient with E200K mutation. Acta Neuropathol 147:89","journal-title":"Acta Neuropathol"}],"container-title":["Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-026-09264-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10072-026-09264-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10072-026-09264-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T02:40:13Z","timestamp":1786588813000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10072-026-09264-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,27]]},"references-count":7,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["9264"],"URL":"https:\/\/doi.org\/10.1007\/s10072-026-09264-1","relation":{},"ISSN":["1590-1874","1590-3478"],"issn-type":[{"value":"1590-1874","type":"print"},{"value":"1590-3478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,27]]},"assertion":[{"value":"5 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the Ethics Committees of the Xuanwu Hospital of Capital Medical University, and it was carried out in compliance with the Declaration of Helsinki\u2019s principles.","order":1,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from the guardian.","order":2,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"During hospitalization, the patient provided written informed consent for the presentation and publication of his anonymized clinical data.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare that they have no Conflict of Interest.","order":4,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"657"}}