{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T12:38:32Z","timestamp":1773319112986,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2002,12,1]],"date-time":"2002-12-01T00:00:00Z","timestamp":1038700800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2002,12]]},"DOI":"10.1007\/s10096-002-0837-7","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T22:53:03Z","timestamp":1576104783000},"page":"849-855","source":"Crossref","is-referenced-by-count":49,"title":["Prevalence and Drug Susceptibility of Pathogens Causing Bloodstream Infections in Northern Italy: A Two-Year Study in 16 Hospitals"],"prefix":"10.1007","volume":"21","author":[{"name":"AMCLI Lombardia Hospital Infections Study Group","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Luzzaro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. F.","family":"Vigan\u00f2","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Fossati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Grossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Sturla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Saudelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Toniolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2002,12,11]]},"reference":[{"key":"0837_CR1","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s100960050453","volume":"19","author":"Mylotte","year":"2000","unstructured":"Mylotte JM, Tayara A (2000) Blood cultures: clinical aspects and controversies. Eur J Clin Microbiol Infect Dis 19:157\u2013163","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"0837_CR2","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1128\/CMR.10.3.444","volume":"10","author":"Reimer","year":"1997","unstructured":"Reimer LG, Wilson ML, Weinstein MP (1997) Update on detection of bacteremia and fungemia. Clin Microbiol Rev 10:444\u2013465","journal-title":"Clin Microbiol Rev"},{"key":"0837_CR3","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1164\/ajrccm.160.3.9808145","volume":"160","author":"DiGiovine","year":"1999","unstructured":"DiGiovine B, Chenoweth C, Watts C, Higgins M (1999) The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit. Am J Respir Crit Care Med 160:976\u2013981","journal-title":"Am J Respir Crit Care Med"},{"issue":"[Suppl 4","key":"0837_CR4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1086\/314078","volume":"31","author":"AW Karchmer","year":"2000","unstructured":"Karchmer AW (2000) Nosocomial bloodstream infections: organisms, risk factors, and implications. Clin Infect Dis 31 [Suppl 4]:139\u2013143","journal-title":"Clin Infect Dis"},{"key":"0837_CR5","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF02771841","volume":"26","author":"Gikas","year":"1998","unstructured":"Gikas A, Samonis G, Christidou A, Papadakis J, Kofteridis D, Tselentis Y, Tsaparas N (1998) Gram-negative bacteremia in non-neutropenic patients: a 3-year review. Infection 26:155\u2013159","journal-title":"Infection"},{"key":"0837_CR6","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1046\/j.1365-2796.1998.00379.x","volume":"244","author":"Leibovici","year":"1998","unstructured":"Leibovici L, Shraga I, Drucker M, Konigsberger H, Samra Z, Pitlik SD (1998) The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J Intern Med 244:379\u2013386","journal-title":"J Intern Med"},{"key":"0837_CR7","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1128\/AAC.42.7.1762","volume":"42","author":"Pfaller","year":"1998","unstructured":"Pfaller MA, Jones RN, Doern GV, Kugler K, the SENTRY Participants Group (1998) Bacterial pathogens isolated from patients with bloodstream infection: frequencies of occurrence and antimicrobial susceptibility patterns from the SENTRY antimicrobial surveillance program (United States and Canada, 1997). Antimicrob Agents Chemother 42:1762\u20131770","journal-title":"Antimicrob Agents Chemother"},{"key":"0837_CR8","unstructured":"Bouza E, P\u00e9rez-Molina J, Mu\u00f1oz P on behalf of the Cooperative Group of the European Study Group on Nosocomial Infections (ESGNI) (1999) Report of ESGNI-001 and ESGNI-002 studies. Bloodstream infections in Europe. Clin Microbiol Infect 5 [Suppl 2]:1\u201312"},{"key":"0837_CR9","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1086\/313710","volume":"30","author":"Fluit","year":"2000","unstructured":"Fluit AC, Jones ME, Schmitz F-J, Acar J, Gupta R, Verhoef J, the SENTRY Participants Group (2000) Antimicrobial susceptibility and frequency of occurrence of clinical blood isolates in Europe from the SENTRY antimicrobial surveillance program, 1997 and 1998. Clin Infect Dis 30:454\u2013460","journal-title":"Clin Infect Dis"},{"key":"0837_CR10","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1046\/j.1198-743X.2001.00239.x","volume":"7","author":"Bax","year":"2001","unstructured":"Bax R, Bywater R, Cornaglia G, Goossens H, Hunter P, Isham V, Jarlier V, Jones R, Phillips I, Sahm D, Senn S, Struelens M, Taylor D, White A (2001) Surveillance of antimicrobial resistance \u2013 what, how and whither? Clin Microbiol Infect 7:316\u2013325","journal-title":"Clin Microbiol Infect"},{"key":"0837_CR11","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1164\/ajrccm.154.3.8810595","volume":"154","author":"Brun-Buisson","year":"1996","unstructured":"Brun-Buisson C, Doyon F, Carlet J, the French Bacteremia-Sepsis Study Group (1996) Bacteremia and severe sepsis in adults: a multicenter prospective survey in ICUs and wards of 24 hospitals. Am J Respir Crit Care Med 154:617\u2013624","journal-title":"Am J Respir Crit Care Med"},{"key":"0837_CR12","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1097\/00003246-199908000-00002","volume":"27","author":"Edgeworth","year":"1999","unstructured":"Edgeworth JD, Treacher DF, Eykyn SJ (1999) A 25-year study of nosocomial bacteremia in an adult intensive care unit. Crit Care Med 27:1421\u20131428","journal-title":"Crit Care Med"},{"key":"0837_CR13","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1053\/jhin.1999.0681","volume":"44","author":"Garrouste-Orgeas","year":"2000","unstructured":"Garrouste-Orgeas M, Chevret S, Mainardi JL, Timsit JF, Misset B, Carlet J (2000) A one-year prospective study of nosocomial bactaeremia in ICU and non-ICU patients and its impact on patient outcome. J Hosp Infect 44:206\u2013213","journal-title":"J Hosp Infect"},{"key":"0837_CR14","unstructured":"National Committee for Clinical Laboratory Standards (1997) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A4. NCCLS, Wayne, PA"},{"key":"0837_CR15","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/clinids\/10.4.867","volume":"10","author":"Jarlier","year":"1998","unstructured":"Jarlier V, Nicolas M-H, Fournier G, Philippon A (1998) Extended broad-spectrum \u00df-lactamases conferring transferable resistance to newer \u00df-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev Infect Dis 10:867\u2013878","journal-title":"Rev Infect Dis"},{"key":"0837_CR16","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1080\/00365549850160945","volume":"30","author":"Dornbusch","year":"1998","unstructured":"Dornbusch K, King A, Legakis N, the European Study Group on Antibiotic Resistance (ESGAR) (1998) Incidence of antibiotic resistance in blood and urine isolates from hospitalized patients. Report from a European collaborative study. Scand J Infect Dis 30:281\u2013288","journal-title":"Scand J Infect Dis"},{"key":"0837_CR17","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/clind\/24.4.584","volume":"24","author":"Weinstein","year":"1997","unstructured":"Weinstein MP, Towns ML, Quartey SM, Mirrett S, Reimer LG, Parmigiani G, Reller LB (1997) The clinical significance of positive blood cultures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults. Clin Infect Dis 24:584\u2013602","journal-title":"Clin Infect Dis"},{"key":"0837_CR18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02565163","volume":"27","author":"Salom\u00c3\u00a3o","year":"1999","unstructured":"Salom\u00e3o R, Rigato O, Pignatari AC, Freudenberg MA, Galanos C (1999) Bloodstream infections: epidemiology, pathophysiology and therapeutic perspectives. Infection 27:1\u201311","journal-title":"Infection"},{"key":"0837_CR19","doi-asserted-by":"crossref","unstructured":"Rahal JJ (2000) Extended-spectrum \u00df-lactamases: how big is the problem? Clin Microbiol Infect 6 [Suppl 2]:2\u20136","DOI":"10.1046\/j.1469-0691.2000.00002.x"},{"key":"0837_CR20","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0891-5520(05)70249-X","volume":"14","author":"Kaye","year":"2000","unstructured":"Kaye KS, Fraimow HS, Abrutyn E (2000) Pathogens resistant to antimicrobial agents. Infect Dis Clin North Am 14:293\u2013319","journal-title":"Infect Dis Clin North Am"},{"key":"0837_CR21","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1128\/AAC.46.1.196-202.2002","volume":"46","author":"Spanu","year":"2002","unstructured":"Spanu T, Luzzaro F, Perilli M, Amicosante G, Toniolo A, Fadda G (2002) Occurrence of extended-spectrum \u00df-lactamases in members of the family Enterobacteriaceae in Italy: implications for resistance to \u00df-lactams and other antimicrobial drugs. Antimicrob Agents Chemother 46:196\u2013202","journal-title":"Antimicrob Agents Chemother"},{"key":"0837_CR22","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1128\/AAC.41.10.2265","volume":"41","author":"Vahaboglu","year":"1997","unstructured":"Vahaboglu H, \u00d6zt\u00fcrk R, Ayg\u00fcn G, Coskunkan F, Yaman A, Kaygusuz A, Leblebicioglu H, Balik I, Aydin K, Otkun M (1997) Widespread detection of PER-1-type extended-spectrum \u00df-lactamases among nosocomial Acinetobacter and Pseudomonas aeruginosa isolates in Turkey: a nationwide multicenter study. Antimicrob Agents Chemother 41:2265\u20132269","journal-title":"Antimicrob Agents Chemother"},{"key":"0837_CR23","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3201\/eid0603.000314","volume":"6","author":"Rossolini","year":"2000","unstructured":"Rossolini GM, Riccio ML, Cornaglia G, Pagani L, Lagatolla C, Selan L, Fontana R (2000) Carbapenem-resistant Pseudomonas aeruginosa with acquired bla VIM metallo-\u00df-lactamase determinants, Italy. Emerg Infect Dis 6:312\u2013313","journal-title":"Emerg Infect Dis"},{"key":"0837_CR24","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1128\/JCM.38.3.1290-1292.2000","volume":"38","author":"Tsakris","year":"2000","unstructured":"Tsakris A, Pournaras S, Woodford N, Palepou M-F, Babini GS, Douboyas J, Livermore DM (2000) Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece. J Clin Microbiol 38:1290\u20131292","journal-title":"J Clin Microbiol"},{"key":"0837_CR25","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1128\/JCM.39.5.1865-1870.2001","volume":"39","author":"Luzzaro","year":"2001","unstructured":"Luzzaro F, Mantengoli E, Perilli M, Lombardi G, Orlandi V, Orsatti A, Amicosante G, Rossolini GM, Toniolo A (2001) Dynamics of a nosocomial outbreak of multidrug-resistant Pseudomonas aeruginosa producing the PER-1 extended-spectrum \u00df-lactamase. J Clin Microbiol 39:1865\u20131870","journal-title":"J Clin Microbiol"},{"key":"0837_CR26","doi-asserted-by":"crossref","first-page":"910","DOI":"10.3201\/eid0705.010528","volume":"7","author":"Docquier","year":"2001","unstructured":"Docquier J-D, Luzzaro F, Amicosante G, Toniolo A, Rossolini GM (2001) Multidrug-resistant Pseudomonas aeruginosa producing PER-1 extended-spectrum serine-\u00df-lactamase and VIM-2 metallo-\u00df-lactamase. Emerg Infect Dis 7:910\u2013911","journal-title":"Emerg Infect Dis"}],"container-title":["European Journal of Clinical Microbiology and Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-002-0837-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-002-0837-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-002-0837-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,11]],"date-time":"2021-02-11T14:44:06Z","timestamp":1613054646000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-002-0837-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["0837"],"URL":"https:\/\/doi.org\/10.1007\/s10096-002-0837-7","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,12]]}}}