{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T17:24:44Z","timestamp":1649006684728},"reference-count":13,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2004,11,17]],"date-time":"2004-11-17T00:00:00Z","timestamp":1100649600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"DOI":"10.1007\/s10096-004-1238-x","type":"journal-article","created":{"date-parts":[[2004,11,16]],"date-time":"2004-11-16T13:19:39Z","timestamp":1100611179000},"source":"Crossref","is-referenced-by-count":1,"title":["Analysis of quasispecies in the viral 5? untranslated region of hepatitis C virus to evaluate ribavirin mutagenic effect in patients receiving ribavirin and interferon-alfa"],"prefix":"10.1007","author":[{"given":"A.","family":"Vallejo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Molina-Pinelo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Abad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"G\ufffdmez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Leal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"S\ufffdnchez-Quijano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Lissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,11,17]]},"reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S1089-3261(05)70234-8","volume":"3","author":"X Forns","year":"1999","unstructured":"Forns X, Bukh J (1999) The molecular biology of hepatitis C virus. Genotypes and quasispecies. Clin Liver Dis 3:693?716","journal-title":"Clin Liver Dis"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1365-2893.1999.t01-1-6120131.x","volume":"6","author":"J Gomez","year":"1999","unstructured":"Gomez J, Martell M, Quer J, Cabot B, Esteban JI (1999) Hepatitis C viral quasispecies. J Viral Hepat 6:3?16","journal-title":"J Viral Hepat"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1073\/pnas.052712599","volume":"99","author":"P Farci","year":"2002","unstructured":"Farci P, Strazzera R, Alter HJ, Farci S, Degioannis D, Coiana A, Peddis G, Usai F, Serra G, Chessa L, Diaz G, Balestrieri A, Purcell RH (2002) Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome. Proc Natl Acad Sci USA 99:3081?3086","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S1386-6532(00)00160-8","volume":"20","author":"B Grahovac","year":"2001","unstructured":"Grahovac B, Bingulac-Popovic J, Vucelic B, Hrstic I, Ostojic R, Drazic V, Balija M, Grgicevic D (2001) Dynamics of serum hepatitis C virus load and quasispecies complexity during antiviral therapy in patients with chronic hepatitis C. J Clin Virol 20:85?89","journal-title":"J Clin Virol"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"12005","DOI":"10.1128\/JVI.75.24.12005-12013.2001","volume":"75","author":"B Cabot","year":"2001","unstructured":"Cabot B, Martell M, Esteban JI, Piron M, Otero T, Esteban R, Guardia J, Gomez J (2001) Longitudinal evaluation of the structure of replicating and circulating hepatitis C virus quasispecies in nonprogressive chronic hepatitis C patients. J Virol 75:12005?12013","journal-title":"J Virol"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1056\/NEJM199811193392101","volume":"339","author":"JG McHutchison","year":"1998","unstructured":"McHutchison JG, Gordon SC, Schiff ER, Shiffman ML, Lee WM, Rustgi VK, Goodman ZD, Ling MH, Cort S, Albrecht JK (1998) Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Eng J Med 339:1485?1492","journal-title":"N Eng J Med"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1016\/S0140-6736(98)07124-4","volume":"353","author":"T Poynard","year":"1998","unstructured":"Poynard T, Marcellin P, Lee SS, Niederau C, Minuk GS, Ideo G, Bain V, Heathcote J, Zeuzem S, Trepo C, Albrecht J (1998) Randomised trial of interferon alfa-2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alfa-2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group. Lancet 353:1426?1432","journal-title":"Lancet"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"8505","DOI":"10.1128\/JVI.76.17.8505-8517.2002","volume":"76","author":"AM Contreras","year":"2002","unstructured":"Contreras AM, Hiasa Y, He W, Terella A, Schmidt EV, Chung RT (2002) Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system. J Virol 76:8505?8517","journal-title":"J Virol"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"6895","DOI":"10.1073\/pnas.111085598","volume":"98","author":"S Crotty","year":"2001","unstructured":"Crotty S, Cameron CE, Andino R (2001) RNA virus error catastrophe: Direct molecular test by using ribavirin. Proc Natl Acad Sci USA 98:6895?6900","journal-title":"PNAS"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"8316","DOI":"10.1128\/JVI.74.18.8316-8323.2000","volume":"74","author":"S Sierra","year":"2000","unstructured":"Sierra S, Davila M, Lowenstein PR, Domingo E (2000) Response of foot-and-mouth disease virus to increased mutagenesis: Influence of viral load and fitness in loss of infectivity. J Virol 74:8316?8323","journal-title":"J Virol"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1006\/viro.2002.1494","volume":"298","author":"M Soler","year":"2002","unstructured":"Soler M, Pellerin M, Malnou CE, Dhumeaux D, Kean KM, Pawlotsky JM (2002) Quasispecies heterogeneity and constraints on the evolution of the 5? noncoding region of hepatitis C virus (HCV): Relationship with HCV resistance to interferon-alpha therapy. Virology 298:160?173","journal-title":"Virology"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1128\/JVI.71.2.1662-1666.1997","volume":"71","author":"S Fukushi","year":"1997","unstructured":"Fukushi S, Kurihara C, Ishiyama N, Hoshino FB, Oya A, Katayama K (1997) The sequence element of the internal ribosome entry site and a 25-kilodalton cellular protein contribute to efficient internal initiation of translation of hepatitis C virus RNA. J Virol 71:1662?1666","journal-title":"J Virol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1017\/S1355838200000935","volume":"6","author":"R Klinck","year":"2000","unstructured":"Klinck R, Westhof E, Walker S, Afshar M, Collier A, Aboul-Ela F (2000) A potential RNA drug target in the hepatitis C virus ribosomal entry site. RNA 6:1423?1431","journal-title":"RNA"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-004-1238-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-004-1238-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-004-1238-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T03:36:00Z","timestamp":1585971360000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-004-1238-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11,17]]},"references-count":13,"alternative-id":["1238"],"URL":"https:\/\/doi.org\/10.1007\/s10096-004-1238-x","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,11,17]]}}}