{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:05:36Z","timestamp":1787501136924,"version":"build-2736575974"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2005,6,15]],"date-time":"2005-06-15T00:00:00Z","timestamp":1118793600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1007\/s10096-005-1349-z","type":"journal-article","created":{"date-parts":[[2005,6,14]],"date-time":"2005-06-14T05:55:01Z","timestamp":1118728501000},"page":"450-456","source":"Crossref","is-referenced-by-count":35,"title":["Human brucellosis in a nonendemic country: a report from Germany, 2002 and 2003"],"prefix":"10.1007","volume":"24","author":[{"given":"S.","family":"Al Dahouk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"N\u00f6ckler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Hensel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Tomaso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. C.","family":"Scholz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Hagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Neubauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,6,15]]},"reference":[{"key":"1349_CR1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3201\/eid0302.970219","volume":"3","author":"MJ Corbel","year":"1997","unstructured":"Corbel MJ (1997) Brucellosis: an overview. Emerg Infect Dis 3:213\u2013221","journal-title":"Emerg Infect Dis"},{"key":"1349_CR2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/978-3-642-59533-2_3","volume-title":"Madkour\u2019s brucellosis","author":"MM Madkour","year":"2001","unstructured":"Madkour MM (2001) Epidemiological aspects. In: Madkour MM (ed) Madkour\u2019s brucellosis. Springer, Berlin, pp 21\u201332"},{"key":"1349_CR3","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/00001432-200204000-00003","volume":"15","author":"EJ Young","year":"1995","unstructured":"Young EJ (1995) Brucellosis: current epidemiology, diagnosis, and management. Curr Clin Top Infect Dis 15:115\u2013128","journal-title":"Curr Clin Top Infect Dis"},{"key":"1349_CR4","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S1286-4579(01)01427-7","volume":"3","author":"A Cloeckaert","year":"2001","unstructured":"Cloeckaert A, Verger JM, Grayon M, Paquet JY, Garin-Bastuji B, Foster G, Godfroid J (2001) Classification of Brucella spp. isolated from marine mammals by DNA polymorphism at the omp2 locus. Microbes Infect 3:729\u2013738","journal-title":"Microbes Infect"},{"key":"1349_CR5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0378-1135(97)00118-1","volume":"57","author":"KL Jahans","year":"1997","unstructured":"Jahans KL, Foster G, Broughton ES (1997) The characterisation of Brucella strains isolated from marine mammals. Vet Microbiol 57:373\u2013382","journal-title":"Vet Microbiol"},{"key":"1349_CR6","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3201\/eid0904.020576","volume":"9","author":"AH Sohn","year":"2003","unstructured":"Sohn AH, Probert WS, Glaser CA, Gupta N, Bollen AW, Wong JD, Grace EM, McDonald WC (2003) Human neurobrucellosis with intracerebral granuloma caused by a marine mammal Brucella spp. Emerg Infect Dis 9:485\u2013488","journal-title":"Emerg Infect Dis"},{"key":"1349_CR7","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/clinids\/21.2.283","volume":"21","author":"EJ Young","year":"1995","unstructured":"Young EJ (1995) An overview of human brucellosis. Clin Infect Dis 21:283\u2013289","journal-title":"Clin Infect Dis"},{"key":"1349_CR8","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/0035-9203(92)90575-W","volume":"86","author":"CW Cooper","year":"1992","unstructured":"Cooper CW (1992) Risk factors in transmission of brucellosis from animals to humans in Saudi Arabia. Trans R Soc Trop Med Hyg 86:206\u2013209","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"1349_CR9","first-page":"387","volume":"50","author":"S Dahouk Al","year":"2004","unstructured":"Al Dahouk S, Tomaso H, N\u00f6ckler K, Neubauer H (2004) The detection of Brucella spp. using PCR-ELISA and real-time PCR assays. Clin Lab 50:387\u2013394","journal-title":"Clin Lab"},{"key":"1349_CR10","first-page":"271","volume":"95","author":"GG Baily","year":"1992","unstructured":"Baily GG, Krahn JB, Drasar BS, Stoker NG (1992) Detection of Brucella melitensis and Brucella abortus by DNA amplification. J Tropical Med Hyg 95:271\u2013275","journal-title":"J Tropical Med Hyg"},{"key":"1349_CR11","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1128\/JCM.32.11.2660-2666.1994","volume":"11","author":"BJ Bricker","year":"1994","unstructured":"Bricker BJ, Halling SM (1994) Differentiation of Brucella abortus bv. 1, 2, and 4, Brucella melitensis, Brucella ovis, and Brucella suis bv. 1 by PCR. J Clin Microbiol 11:2660\u20132666","journal-title":"J Clin Microbiol"},{"key":"1349_CR12","first-page":"487","volume":"49","author":"S Dahouk Al","year":"2003","unstructured":"Al Dahouk S, Tomaso H, N\u00f6ckler K, Neubauer H, Frangoulidis D (2003) Laboratory-based diagnosis of brucellosis\u2014a review of the literature. Part I: techniques for direct detection and identification of Brucella spp. Clin Lab 49:487\u2013505","journal-title":"Clin Lab"},{"key":"1349_CR13","volume-title":"Techniques for the brucellosis laboratory","author":"GG Alton","year":"1988","unstructured":"Alton GG, Jones LM, Angus RD, Verger JM (1988) Techniques for the brucellosis laboratory. Institut National de la Recherche Agronomique, Paris"},{"key":"1349_CR14","first-page":"2039","volume-title":"Topley & Wilson\u2019s microbiology and microbial infections","author":"MJ Corbel","year":"1998","unstructured":"Corbel MJ, MacMillan AP (1998) Brucellosis. In: Colloer LH, Balows A (eds) Topley & Wilson\u2019s microbiology and microbial infections. Arnold, London, pp 2039\u20132068"},{"key":"1349_CR15","first-page":"577","volume":"49","author":"S Dahouk Al","year":"2003","unstructured":"Al Dahouk S, Tomaso H, N\u00f6ckler K, Neubauer H, Frangoulidis D (2003) Laboratory-based diagnosis of brucellosis \u2013 a review of the literature. Part II: serological tests for brucellosis. Clin Lab 49:577\u2013589","journal-title":"Clin Lab"},{"key":"1349_CR16","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0378-1135(02)00217-1","volume":"90","author":"J Godfroid","year":"2002","unstructured":"Godfroid J, K\u00e4sbohrer A (2002) Brucellosis in the European Union and Norway at the turn of the twenty-first century. Vet Microbiol 90:135\u2013145","journal-title":"Vet Microbiol"},{"key":"1349_CR17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.2310\/7060.2004.13551","volume":"11","author":"ZA Memish","year":"2004","unstructured":"Memish ZA, Balkhy HH (2004) Brucellosis and international travel. J Travel Med 11:49\u201355","journal-title":"J Travel Med"},{"key":"1349_CR18","doi-asserted-by":"crossref","first-page":"672","DOI":"10.3201\/eid0807.010351","volume":"8","author":"GT Fosgate","year":"2002","unstructured":"Fosgate GT, Carpenter TE, Chomel BB, Case JT, DeBess EE, Reilly KF (2002) Time-space clustering of human brucellosis, California, 1973\u20131992. Emerg Infect Dis 8:672\u2013678","journal-title":"Emerg Infect Dis"},{"key":"1349_CR19","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1086\/340620","volume":"34","author":"AC White Jr","year":"2002","unstructured":"White AC Jr, Atmar RL (2002) Infections in Hispanic immigrants. Clin Infect Dis 34:1627\u20131632","journal-title":"Clin Infect Dis"},{"key":"1349_CR20","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1080\/003655402320208811","volume":"34","author":"N Eriksen","year":"2002","unstructured":"Eriksen N, Lemming L, Hojlyng N, Bruun B (2002) Brucellosis in immigrants in Denmark. Scand J Infect Dis 34:540\u2013542","journal-title":"Scand J Infect Dis"},{"key":"1349_CR21","unstructured":"Statistisches Bundesamt Deutschland (2004) Bev\u00f6lkerung nach Geschlecht und Staatsangeh\u00f6rigkeit. http:\/\/www.destatis.de\/basis\/d\/bevoe\/bevoetab4.php. Cited 8 July 2004"},{"key":"1349_CR22","unstructured":"Forschungsgemeinschaft Urlaub und Reisen e.V. (2003) Die 33. Reiseanalyse RA 2003, Hamburg\/Kiel. http:\/\/www.fur.de. Cited August 2003"},{"key":"1349_CR23","unstructured":"Forschungsgemeinschaft Urlaub und Reisen e.V. (2004) Die 34. Reiseanalyse RA 2004, Hamburg\/Kiel. http:\/\/www.fur.de. Cited October 2004"},{"key":"1349_CR24","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0378-1135(02)00250-X","volume":"90","author":"V Taleski","year":"2002","unstructured":"Taleski V, Zerva L, Kantardjiev T, Cvetnic Z, Erski-Biljic M, Nikolovski B, Bosnjakovski J, Katalinic-Jankovic V, Panteliadou A, Stojkoski S, Kirandziski T (2002) An overview of the epidemiology and epizootology of brucellosis in selected countries of Central and Southeast Europe. Vet Microbiol 90:147\u2013155","journal-title":"Vet Microbiol"},{"key":"1349_CR25","unstructured":"Kilic D, Kaya I, Kamas A (2003) Distribution of inpatients by diseases at the hospital in Turkey, 2000. In: Research, Planning and Coordination Council (eds) Health statistics 2002. Ministry of Health, Ankara, Republic of Turkey, p 64"},{"key":"1349_CR26","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1742-1241.2003.tb11391.x","volume":"57","author":"M Namiduru","year":"2003","unstructured":"Namiduru M, Gungor K, Dikensoy O, Baydar I, Ekinci E, Karaoglan I, Bekir NA (2003) Epidemiological, clinical and laboratory features of brucellosis: a prospective evaluation of 120 adult patients. Int J Clin Pract 57:20\u201324","journal-title":"Int J Clin Pract"},{"key":"1349_CR27","first-page":"381","volume":"8","author":"A Mert","year":"2002","unstructured":"Mert A, Kocak F, Ozaras R, Tabak F, Bilir M, Kucukuglu S, Ozturk R, Aktuglu Y (2002) The role of antibiotic treatment alone for the management of Brucella endocarditis in adults: a case report and literature review. Ann Thorac Cardiovasc Surg 8:381\u2013385","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"1349_CR28","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00005792-199607000-00003","volume":"75","author":"JD Colmenero","year":"1996","unstructured":"Colmenero JD, Reguera JM, Martos F, Sanchez-De-Mora D, Delgado M, Causse M, Martin-Farfan A, Juarez C (1996) Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine (Baltimore) 75:195\u2013211","journal-title":"Medicine (Baltimore)"},{"key":"1349_CR29","first-page":"39","volume":"66","author":"AR Lulu","year":"1988","unstructured":"Lulu AR, Araj GF, Khateeb MI, Mustafa MY, Yusuf AR, Fenech FF (1988) Human brucellosis in Kuwait: a prospective study of 400 cases. Q J Med 66:39\u201354","journal-title":"Q J Med"},{"key":"1349_CR30","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1017\/S0950268804002833","volume":"132","author":"MR Hasanjani Roushan","year":"2004","unstructured":"Hasanjani Roushan MR, Mohrez M, Smailnejad Gangi SM, Soleimani Amiri MJ, Hajiahmadi M (2004) Epidemiological features and clinical manifestations in 469 adult patients with brucellosis in Babol, Northern Iran. Epidemiol Infect 132:1109\u20131114","journal-title":"Epidemiol Infect"},{"key":"1349_CR31","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1053\/jinf.1999.0586","volume":"40","author":"Z Memish","year":"2000","unstructured":"Memish Z, Mah MW, Al Mahmoud S, Al Shaalan M, Khan MY (2000) Brucella bacteraemia: clinical and laboratory observations in 160 patients. J Infect 40:59\u201363","journal-title":"J Infect"},{"key":"1349_CR32","first-page":"11","volume":"29","author":"AM Yinnon","year":"1993","unstructured":"Yinnon AM, Morali GA, Goren A, Rudensky B, Isacsohn M, Michel J, Hershko C (1993) Effect of age and duration of disease on the clinical manifestations of brucellosis. A study of 73 consecutive patients in Israel. Isr J Med Sci 29:11\u201316","journal-title":"Isr J Med Sci"},{"key":"1349_CR33","doi-asserted-by":"crossref","first-page":"12","DOI":"10.5144\/0256-4947.1994.12","volume":"14","author":"SR Al-Ballaa","year":"1994","unstructured":"Al-Ballaa SR, Al-Balla SR, Al-Aska A, Kambal A, Al-Hedaithy MA (1994) Seasonal variation of culture positive brucellosis at a major teaching hospital. Ann Saudi Med 14:12\u201315","journal-title":"Ann Saudi Med"},{"key":"1349_CR34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3349\/ymj.2003.44.1.33","volume":"44","author":"A Gur","year":"2003","unstructured":"Gur A, Geyik MF, Dikici B, Nas K, Cevik R, Sarac J, Hosoglu S (2003) Complications of brucellosis in different age groups: a study of 283 cases in southeastern Anatolia of Turkey. Yonsei Med J 44:33\u201344","journal-title":"Yonsei Med J"},{"key":"1349_CR35","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jinf.2003.08.006","volume":"48","author":"N Saltoglu","year":"2004","unstructured":"Saltoglu N, Tasova Y, Midikli D, Aksu HS, Sanli A, Dundar IH (2004) Fever of unknown origin in Turkey: evaluation of 87 cases during a nine-year-period of study. J Infect 48:81\u201385","journal-title":"J Infect"},{"key":"1349_CR36","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1600-0609.1986.tb01746.x","volume":"36","author":"MH Aysha","year":"1986","unstructured":"Aysha MH, Shayib MA (1986) Pancytopenia and other haematological findings in brucellosis. Scand J Haematol 36:335\u2013338","journal-title":"Scand J Haematol"},{"key":"1349_CR37","doi-asserted-by":"crossref","first-page":"e95","DOI":"10.1086\/378125","volume":"37","author":"G Pappas","year":"2003","unstructured":"Pappas G, Bosilkovski M, Akritidis N, Mastora M, Krteva L, Tsianos E (2003) Brucellosis and the respiratory system. Clin Infect Dis 37:e95\u2013e99","journal-title":"Clin Infect Dis"},{"key":"1349_CR38","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1093\/clind\/15.4.582","volume":"15","author":"DR McLean","year":"1992","unstructured":"McLean DR, Russell N, Khan MY (1992) Neurobrucellosis: clinical and therapeutic features. Clin Infect Dis 15:582\u2013590","journal-title":"Clin Infect Dis"},{"key":"1349_CR39","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1080\/00365540210147561","volume":"34","author":"M Yilmaz","year":"2002","unstructured":"Yilmaz M, Ozaras R, Ozturk R, Mert A, Tabak F, Aktuglu Y (2002) Epileptic seizure: an atypical presentation in an adolescent boy with neurobrucellosis. Scand J Infect Dis 34:623\u2013625","journal-title":"Scand J Infect Dis"},{"key":"1349_CR40","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jinf.2004.02.005","volume":"50","author":"B Dokuzoguz","year":"2005","unstructured":"Dokuzoguz B, Ergonul O, Baykam N, Esener H, Kilic S, Celikbas A, Eren S, Esen B (2005) Characteristics of Brucella melitensis versus Brucella abortus bacteraemias. J Infect 50:41\u201345","journal-title":"J Infect"},{"key":"1349_CR41","first-page":"56","volume-title":"Joint FAO\/WHO Expert Committee on Brucellosis (6th report). WHO Technical Report Series No. 740","author":"Food and Agriculture Organization \u2013 World Health Organization","year":"1986","unstructured":"Food and Agriculture Organization \u2013 World Health Organization (1986) Joint FAO\/WHO Expert Committee on Brucellosis (6th report). WHO Technical Report Series No. 740. WHO, Geneva, pp 56\u201357"},{"key":"1349_CR42","first-page":"34","volume-title":"Joint FAO\/WHO Expert Committee on Brucellosis (5th report). WHO Technical Report Series No. 464","author":"Food and Agriculture Organization\u2014World Health Organization","year":"1971","unstructured":"Food and Agriculture Organization\u2014World Health Organization (1971) Joint FAO\/WHO Expert Committee on Brucellosis (5th report). WHO Technical Report Series No. 464. WHO, Geneva, pp 34\u201336"},{"key":"1349_CR43","doi-asserted-by":"crossref","first-page":"25","DOI":"10.7326\/0003-4819-117-1-25","volume":"117","author":"J Ariza","year":"1992","unstructured":"Ariza J, Gudiol F, Pallares R, Viladrich PF, Rufi G, Corredoira J, Miravitlles MR (1992) Treatment of human brucellosis with doxycycline plus rifampin or doxycycline plus streptomycin. A randomized, double-blind study. Ann Intern Med 117:25\u201330","journal-title":"Ann Intern Med"},{"key":"1349_CR44","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1128\/AAC.39.9.2061","volume":"39","author":"J Solera","year":"1995","unstructured":"Solera J, Rodr\u00edguez-Zapata M, Geijo P, Largo J, Paulino J, S\u00e1ez L, Mart\u00ednez-Alfaro E, S\u00e1nchez L, Sepulveda MA, Ruiz-Rib\u00f3 MD (1995) Doxycycline-rifampin versus doxycycline-streptomycin in treatment of human brucellosis due to Brucella melitensis. The GECMEI Group. Grupo de Estudio de Castilla-la Mancha de Enfermedades Infecciosas. Antimicrob Agents Chemother 39:2061\u20132067","journal-title":"Antimicrob Agents Chemother"},{"key":"1349_CR45","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1128\/AAC.33.8.1409","volume":"33","author":"MY Khan","year":"1989","unstructured":"Khan MY, Dizon M, Kiel FW (1989) Comparative in vitro activities of ofloxacin, difloxacin, ciprofloxacin, and other selected antimicrobial agents against Brucella melitensis. Antimicrob Agents Chemother 33:1409\u20131410","journal-title":"Antimicrob Agents Chemother"},{"key":"1349_CR46","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/jac\/29.4.357","volume":"29","author":"R Lang","year":"1992","unstructured":"Lang R, Rubinstein E (1992) Quinolones for the treatment of brucellosis. J Antimicrob Chemother 29:357\u2013363","journal-title":"J Antimicrob Chemother"},{"key":"1349_CR47","first-page":"673","volume":"36","author":"TM Peery","year":"1960","unstructured":"Peery TM, Belter LF (1960) Brucellosis and heart disease. II. Fatal brucellosis: a review of the literature and report of new cases. Am J Pathol 36:673\u2013697","journal-title":"Am J Pathol"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-005-1349-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-005-1349-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-005-1349-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T07:10:32Z","timestamp":1683097832000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-005-1349-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6,15]]},"references-count":47,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["1349"],"URL":"https:\/\/doi.org\/10.1007\/s10096-005-1349-z","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6,15]]}}}