{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:17:54Z","timestamp":1790518674581,"version":"4.1.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,8,2]],"date-time":"2008-08-02T00:00:00Z","timestamp":1217635200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1007\/s10096-008-0592-5","type":"journal-article","created":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T07:26:22Z","timestamp":1217575582000},"page":"55-60","source":"Crossref","is-referenced-by-count":54,"title":["Prognostic value of procalcitonin in Legionella pneumonia"],"prefix":"10.1007","volume":"28","author":[{"given":"J.","family":"Haeuptle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Zaborsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Fiumefreddo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Trampuz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Steffen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Frei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Christ-Crain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Schuetz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,8,2]]},"reference":[{"key":"592_CR1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1471-2334-7-10","volume":"7","author":"B Muller","year":"2007","unstructured":"Muller B, Harbarth S, Stolz D, Bingisser R, Mueller C, Leuppi J et al (2007) Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumonia. BMC Infect Dis 7:10. doi: 10.1186\/1471-2334-7-10","journal-title":"BMC Infect Dis"},{"issue":"2","key":"592_CR2","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1086\/421997","volume":"39","author":"L Simon","year":"2004","unstructured":"Simon L, Gauvin F, Amre DK, Saint-Louis P, Lacroix J (2004) Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis 39(2):206\u2013217. doi: 10.1086\/421997","journal-title":"Clin Infect Dis"},{"issue":"9409","key":"592_CR3","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S0140-6736(04)15591-8","volume":"363","author":"M Christ-Crain","year":"2004","unstructured":"Christ-Crain M, Jaccard-Stolz D, Bingisser R, Gencay MM, Huber PR, Tamm M et al (2004) Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 363(9409):600\u2013607. doi: 10.1016\/S0140-6736(04)15591-8","journal-title":"Lancet"},{"key":"592_CR4","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1471-2296-6-34","volume":"6","author":"M Briel","year":"2005","unstructured":"Briel M, Christ-Crain M, Young J, Schuetz P, Huber P, Periat P et al (2005) Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners. BMC Fam Pract 6:34. doi: 10.1186\/1471-2296-6-34","journal-title":"BMC Fam Pract"},{"issue":"1","key":"592_CR5","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1164\/rccm.200512-1922OC","volume":"174","author":"M Christ-Crain","year":"2006","unstructured":"Christ-Crain M, Stolz D, Bingisser R, Muller C, Miedinger D, Huber PR et al (2006) Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med 174(1):84\u201393. doi: 10.1164\/rccm.200512-1922OC","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"592_CR6","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1378\/chest.06-1500","volume":"131","author":"D Stolz","year":"2007","unstructured":"Stolz D, Christ-Crain M, Bingisser R, Leuppi J, Miedinger D, Muller C et al (2007) Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy. Chest 131(1):9\u201319. doi: 10.1378\/chest.06-1500","journal-title":"Chest"},{"issue":"10","key":"592_CR7","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1097\/01.CCM.0000239116.01855.61","volume":"34","author":"JU Jensen","year":"2006","unstructured":"Jensen JU, Heslet L, Jensen TH, Espersen K, Steffensen P, Tvede M (2006) Procalcitonin increase in early identification of critically ill patients at high risk of mortality. Crit Care Med 34(10):2596\u20132602. doi: 10.1097\/01.CCM.0000239116.01855.61","journal-title":"Crit Care Med"},{"issue":"3","key":"592_CR8","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1164\/ajrccm.164.3.2009052","volume":"164","author":"S Harbarth","year":"2001","unstructured":"Harbarth S, Holeckova K, Froidevaux C, Pittet D, Ricou B, Grau GE et al (2001) Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 164(3):396\u2013402","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"592_CR9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1469-0691.2006.01629.x","volume":"13","author":"M Masia","year":"2007","unstructured":"Masia M, Gutierrez F, Padilla S, Soldan B, Mirete C, Shum C et al (2007) Clinical characterisation of pneumonia caused by atypical pathogens combining classic and novel predictors. Clin Microbiol Infect 13(2):153\u2013161. doi: 10.1111\/j.1469-0691.2006.01629.x","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"592_CR10","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/ppul.10201","volume":"35","author":"M Korppi","year":"2003","unstructured":"Korppi M, Remes S, Heiskanen-Kosma T (2003) Serum procalcitonin concentrations in bacterial pneumonia in children: a negative result in primary healthcare settings. Pediatr Pulmonol 35(1):56\u201361. doi: 10.1002\/ppul.10201","journal-title":"Pediatr Pulmonol"},{"issue":"1","key":"592_CR11","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00284-004-4360-1","volume":"50","author":"L Franzin","year":"2005","unstructured":"Franzin L, Cabodi D (2005) Legionella pneumonia and serum procalcitonin. Curr Microbiol 50(1):43\u201346. doi: 10.1007\/s00284-004-4360-1","journal-title":"Curr Microbiol"},{"issue":"3","key":"592_CR12","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jinf.2005.05.019","volume":"52","author":"C Prat","year":"2006","unstructured":"Prat C, Dominguez J, Andreo F, Blanco S, Pallares A, Cuchillo F et al (2006) Procalcitonin and neopterin correlation with aetiology and severity of pneumonia. J Infect 52(3):169\u2013177. doi: 10.1016\/j.jinf.2005.05.019","journal-title":"J Infect"},{"issue":"10","key":"592_CR13","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1056\/NEJM199709043371006","volume":"337","author":"JE Stout","year":"1997","unstructured":"Stout JE, Yu VL (1997) Legionellosis. N Engl J Med 337(10):682\u2013687. doi: 10.1056\/NEJM199709043371006","journal-title":"N Engl J Med"},{"issue":"5","key":"592_CR14","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1136\/thorax.58.5.377","volume":"58","author":"WS Lim","year":"2003","unstructured":"Lim WS, van der Eerden MM, Laing R, Boersma WG, Karalus N, Town GI et al (2003) Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax 58(5):377\u2013382. doi: 10.1136\/thorax.58.5.377","journal-title":"Thorax"},{"issue":"4","key":"592_CR15","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1056\/NEJM199701233360402","volume":"336","author":"MJ Fine","year":"1997","unstructured":"Fine MJ, Auble TE, Yealy DM, Hanusa BH, Weissfeld LA, Singer DE et al (1997) A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 336(4):243\u2013250. doi: 10.1056\/NEJM199701233360402","journal-title":"N Engl J Med"},{"issue":"10","key":"592_CR16","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1136\/thx.51.10.1010","volume":"51","author":"AM Neill","year":"1996","unstructured":"Neill AM, Martin IR, Weir R, Anderson R, Chereshsky A, Epton MJ et al (1996) Community acquired pneumonia: aetiology and usefulness of severity criteria on admission. Thorax 51(10):1010\u20131016","journal-title":"Thorax"},{"issue":"6","key":"592_CR17","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1183\/09031936.05.00055705","volume":"26","author":"M Woodhead","year":"2005","unstructured":"Woodhead M, Blasi F, Ewig S, Huchon G, Leven M, Ortqvist A et al (2005) Guidelines for the management of adult lower respiratory tract infections. Eur Respir J 26(6):1138\u20131180. doi: 10.1183\/09031936.05.00055705","journal-title":"Eur Respir J"},{"issue":"9","key":"592_CR18","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1128\/JCM.36.9.2718-2722.1998","volume":"36","author":"JA Dominguez","year":"1998","unstructured":"Dominguez JA, Gali N, Pedroso P, Fargas A, Padilla E, Manterola JM et al (1998) Comparison of the Binax Legionella urinary antigen enzyme immunoassay (EIA) with the Biotest Legionella Urin antigen EIA for detection of Legionella antigen in both concentrated and nonconcentrated urine samples. J Clin Microbiol 36(9):2718\u20132722","journal-title":"J Clin Microbiol"},{"issue":"10","key":"592_CR19","doi-asserted-by":"crossref","first-page":"2764","DOI":"10.1128\/JCM.31.10.2764-2768.1993","volume":"31","author":"TC Lee","year":"1993","unstructured":"Lee TC, Vickers RM, Yu VL, Wagener MM (1993) Growth of 28 Legionella species on selective culture media: a comparative study. J Clin Microbiol 31(10):2764\u20132768","journal-title":"J Clin Microbiol"},{"key":"592_CR20","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1472-6963-7-102","volume":"7","author":"P Schuetz","year":"2007","unstructured":"Schuetz P, Christ-Crain M, Wolbers M, Schild U, Thomann R, Falconnier C et al (2007) Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial. BMC Health Serv Res 7:102. doi: 10.1186\/1472-6963-7-102","journal-title":"BMC Health Serv Res"},{"issue":"5","key":"592_CR21","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1097\/MCC.0b013e3282c9ac2a","volume":"13","author":"P Schuetz","year":"2007","unstructured":"Schuetz P, Christ-Crain M, Muller B (2007) Biomarkers to improve diagnostic and prognostic accuracy in systemic infections. Curr Opin Crit Care 13(5):578\u2013585. doi: 10.1097\/MCC.0b013e3282c9ac2a","journal-title":"Curr Opin Crit Care"},{"key":"592_CR22","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1086\/368088","volume":"36","author":"ES Nylen","year":"2003","unstructured":"Nylen ES, Muller B, Becker KL, Snyder RH (2003) The future diagnostic role of procalcitonin levels: the need for improved sensitivity. Clin Infect Dis 36:823\u2013824. doi: 10.1086\/368088","journal-title":"Clin Infect Dis"},{"issue":"3","key":"592_CR23","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S1473-3099(07)70052-X","volume":"7","author":"BM Tang","year":"2007","unstructured":"Tang BM, Eslick GD, Craig JC, McLean AS (2007) Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis. Lancet Infect Dis 7(3):210\u2013217. doi: 10.1016\/S1473-3099(07)70052-X","journal-title":"Lancet Infect Dis"},{"issue":"8","key":"592_CR24","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S1473-3099(07)70163-9","volume":"7","author":"B Muller","year":"2007","unstructured":"Muller B, Christ-Crain M, Schuetz P (2007) Meta-analysis of procalcitonin for sepsis detection. Lancet Infect Dis 7(8):498\u2013499, author reply 502\u20133. doi: 10.1016\/S1473-3099(07)70163-9","journal-title":"Lancet Infect Dis"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-008-0592-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-008-0592-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-008-0592-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T11:28:21Z","timestamp":1588850901000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-008-0592-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,2]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["592"],"URL":"https:\/\/doi.org\/10.1007\/s10096-008-0592-5","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8,2]]}}}