{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T17:44:45Z","timestamp":1757699085190},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2008,12,9]],"date-time":"2008-12-09T00:00:00Z","timestamp":1228780800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1007\/s10096-008-0675-3","type":"journal-article","created":{"date-parts":[[2008,12,8]],"date-time":"2008-12-08T12:59:43Z","timestamp":1228741183000},"page":"585-590","source":"Crossref","is-referenced-by-count":11,"title":["Methicillin-resistant Staphylococcus aureus bacteraemia and mortality in a teaching hospital"],"prefix":"10.1007","volume":"28","author":[{"given":"C. J.","family":"Beeston","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. R.","family":"Chadwick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. J.","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,12,9]]},"reference":[{"issue":"3","key":"675_CR1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1093\/jac\/dki266","volume":"56","author":"AP Johnson","year":"2005","unstructured":"Johnson AP, Pearson A, Duckworth G (2005) Surveillance and epidemiology of MRSA bacteraemia in the UK. J Antimicrob Chemother 56(3):455\u2013462, doi: 10.1093\/jac\/dki266","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"675_CR2","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1086\/345476","volume":"36","author":"SE Cosgrove","year":"2003","unstructured":"Cosgrove SE, Sakoulas G, Perencevich EN, Schwaber MJ, Karchmer AW, Carmeli Y (2003) Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis 36(1):53\u201359, doi: 10.1086\/345476","journal-title":"Clin Infect Dis"},{"issue":"2","key":"675_CR3","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1086\/502522","volume":"26","author":"SE Cosgrove","year":"2005","unstructured":"Cosgrove SE, Qi Y, Kaye KS, Harbarth S, Karchmer AW, Carmeli Y (2005) The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infect Control Hosp Epidemiol 26(2):166\u2013174, doi: 10.1086\/502522","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"7","key":"675_CR4","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1128\/AAC.00939-06","volume":"51","author":"PA Moise","year":"2007","unstructured":"Moise PA, Sakoulas G, Forrest A, Schentag JJ (2007) Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother 51(7):2582\u20132586, doi: 10.1128\/AAC.00939-06","journal-title":"Antimicrob Agents Chemother"},{"issue":"6","key":"675_CR5","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1128\/JCM.42.6.2398-2402.2004","volume":"42","author":"G Sakoulas","year":"2004","unstructured":"Sakoulas G, Moise-Broder PA, Schentag J, Forrest A, Moellering RC Jr, Eliopoulos GM (2004) Relationship of MIC and bactericidal activity to efficacy of vancomycin for treatment of methicillin-resistant Staphylococcus aureus bacteremia. J Clin Microbiol 42(6):2398\u20132402, doi: 10.1128\/JCM.42.6.2398-2402.2004","journal-title":"J Clin Microbiol"},{"key":"675_CR6","unstructured":"Chief Medical Officer. Surveillance of Healthcare Associated Infections. CMO Letter PL\/CMO\/2003\/4, PL\/CNO\/2003\/4. London: Department of Health, 9 June 2003"},{"issue":"Suppl 1","key":"675_CR7","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/jac\/48.suppl_1.5","volume":"48","author":"JM Andrews","year":"2001","unstructured":"Andrews JM (2001) Determination of minimum inhibitory concentrations. J Antimicrob Chemother 48(Suppl 1):5\u201316","journal-title":"J Antimicrob Chemother"},{"key":"675_CR8","doi-asserted-by":"crossref","first-page":"2439","DOI":"10.1128\/JCM.39.7.2439-2444.2001","volume":"39","author":"TR Walsh","year":"2001","unstructured":"Walsh TR, Bolmstr\u00f6m A, Qw\u00e4rnstr\u00f6m A, Ho P, Wootton M, Howe RA et al (2001) Evaluation of current methods for detection of staphylococci with reduced susceptibility to glycopeptides. J Clin Microbiol 39:2439\u20132444, doi: 10.1128\/JCM.39.7.2439-2444.2001","journal-title":"J Clin Microbiol"},{"key":"675_CR9","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jhin.2006.05.003","volume":"64","author":"APR Wilson","year":"2006","unstructured":"Wilson APR, Hayman S, Cepeda JA, Singer M, Bellingan G (2006) Screening for MRSA and GISA in the intensive care unit. J Hosp Infect 64:85\u201394, doi: 10.1016\/j.jhin.2006.05.003","journal-title":"J Hosp Infect"},{"key":"675_CR10","unstructured":"[No authors listed] (1995) Epidemic methicillin resistant Staphylococcus aureus. Commun Dis Rep 351(5)"},{"issue":"1","key":"675_CR11","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0195-6701(97)90071-2","volume":"37","author":"R Coello","year":"1997","unstructured":"Coello R, Glynn JR, Gaspar C, Picazo JJ, Fereres J (1997) Risk factors for developing clinical infection with methicillin-resistant Staphylococcus aureus (MRSA) amongst hospital patients initially only colonized with MRSA. J Hosp Infect 37(1):39\u201346, doi: 10.1016\/S0195-6701(97)90071-2","journal-title":"J Hosp Infect"},{"issue":"1","key":"675_CR12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.2307\/30142361","volume":"17","author":"A Asensio","year":"1996","unstructured":"Asensio A, Guerrero A, Quereda C, Liz\u00e1n M, Martinez-Ferrer M (1996) Colonization and infection with methicillin-resistant Staphylococcus aureus: associated factors and eradication. Infect Control Hosp Epidemiol 17(1):20\u201328","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"5","key":"675_CR13","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/01.md.0000091185.93122.40","volume":"82","author":"FY Chang","year":"2003","unstructured":"Chang FY, MacDonald BB, Peacock JE Jr, Musher DM, Triplett P, Mylotte JM et al (2003) A prospective multicenter study of Staphylococcus aureus bacteremia: incidence of endocarditis, risk factors for mortality, and clinical impact of methicillin resistance. Medicine (Baltimore) 82(5):322\u2013332, doi: 10.1097\/01.md.0000091185.93122.40","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"675_CR14","first-page":"24","volume":"37","author":"JC Lin","year":"2004","unstructured":"Lin JC, Yeh KM, Peng MY, Chang FY (2004) Community-acquired methicillin-resistant Staphylococcus aureus bacteremia in Taiwan: risk factors for acquisition, clinical features and outcome. J Microbiol Immunol Infect 37(1):24\u201328","journal-title":"J Microbiol Immunol Infect"},{"issue":"5","key":"675_CR15","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1086\/317421","volume":"31","author":"JM Mylotte","year":"2000","unstructured":"Mylotte JM, Tayara A (2000) Staphylococcus aureus bacteremia: predictors of 30-day mortality in a large cohort. Clin Infect Dis 31(5):1170\u20131174, doi: 10.1086\/317421","journal-title":"Clin Infect Dis"},{"issue":"4","key":"675_CR16","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1469-0691.2005.01359.x","volume":"12","author":"C Kaech","year":"2006","unstructured":"Kaech C, Elzi L, Sendi P, Frei R, Laifer G, Bassetti S et al (2006) Course and outcome of Staphylococcus aureus bacteraemia: a retrospective analysis of 308 episodes in a Swiss tertiary-care centre. Clin Microbiol Infect 12(4):345\u2013352, doi: 10.1111\/j.1469-0691.2005.01359.x","journal-title":"Clin Microbiol Infect"},{"issue":"11","key":"675_CR17","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1086\/375057","volume":"36","author":"TP Lodise","year":"2003","unstructured":"Lodise TP, McKinnon PS, Swiderski L, Rybak MJ (2003) Outcomes analysis of delayed antibiotic treatment for hospital-acquired Staphylococcus aureus bacteremia. Clin Infect Dis 36(11):1418\u20131423, doi: 10.1086\/375057","journal-title":"Clin Infect Dis"},{"issue":"3","key":"675_CR18","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.jhin.2006.02.011","volume":"63","author":"AO Guilarde","year":"2006","unstructured":"Guilarde AO, Turchi MD, Martelli CM, Primo MG (2006) Staphylococcus aureus bacteraemia: incidence, risk factors and predictors for death in a Brazilian teaching hospital. J Hosp Infect 63(3):330\u2013336, doi: 10.1016\/j.jhin.2006.02.011","journal-title":"J Hosp Infect"},{"issue":"1","key":"675_CR19","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1378\/chest.118.1.146","volume":"118","author":"EH Ibrahim","year":"2000","unstructured":"Ibrahim EH, Sherman G, Ward S, Fraser VJ, Kollef MH (2000) The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 118(1):146\u2013155, doi: 10.1378\/chest.118.1.146","journal-title":"Chest"},{"issue":"2","key":"675_CR20","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/jac\/dkh366","volume":"54","author":"SH Kim","year":"2004","unstructured":"Kim SH, Park WB, Lee KD, Kang CI, Bang JW, Kim HB et al (2004) Outcome of inappropriate initial antimicrobial treatment in patients with methicillin-resistant Staphylococcus aureus bacteraemia. J Antimicrob Chemother 54(2):489\u2013497, doi: 10.1093\/jac\/dkh366","journal-title":"J Antimicrob Chemother"},{"issue":"7","key":"675_CR21","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1001\/archinte.160.7.1001","volume":"160","author":"MC Roghmann","year":"2000","unstructured":"Roghmann MC (2000) Predicting methicillin resistance and the effect of inadequate empiric therapy on survival in patients with Staphylococcus aureus bacteremia. Arch Intern Med 160(7):1001\u20131004, doi: 10.1001\/archinte.160.7.1001","journal-title":"Arch Intern Med"},{"issue":"3","key":"675_CR22","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/jac\/dkl006","volume":"57","author":"CT Fang","year":"2006","unstructured":"Fang CT, Shau WY, Hsueh PR, Chen YC, Wang JT, Hung CC et al (2006) Early empirical glycopeptide therapy for patients with methicillin-resistant Staphylococcus aureus bacteraemia: impact on the outcome. J Antimicrob Chemother 57(3):511\u2013519, doi: 10.1093\/jac\/dkl006","journal-title":"J Antimicrob Chemother"},{"issue":"3","key":"675_CR23","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10096-006-0096-0","volume":"25","author":"R Khatib","year":"2006","unstructured":"Khatib R, Saeed S, Sharma M, Riederer K, Fakih MG, Johnson LB (2006) Impact of initial antibiotic choice and delayed appropriate treatment on the outcome of Staphylococcus aureus bacteremia. Eur J Clin Microbiol Infect Dis 25(3):181\u2013185, doi: 10.1007\/s10096-006-0096-0","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"8","key":"675_CR24","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.clinthera.2006.08.003","volume":"28","author":"DO Maclayton","year":"2006","unstructured":"Maclayton DO, Suda KJ, Coval KA, York CB, Garey KW (2006) Case-control study of the relationship between MRSA bacteremia with a vancomycin MIC of 2 microg\/mL and risk factors, costs, and outcomes in inpatients undergoing hemodialysis. Clin Ther 28(8):1208\u20131216, doi: 10.1016\/j.clinthera.2006.08.003","journal-title":"Clin Ther"},{"issue":"1","key":"675_CR25","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/jac\/dkm445","volume":"61","author":"PA Moise","year":"2008","unstructured":"Moise PA, Smyth DS, El-Fawal N, Robinson DA, Holden PN, Forrest A et al (2008) Microbiological effects of prior vancomycin use in patients with methicillin-resistant Staphylococcus aureus bacteraemia. J Antimicrob Chemother 61(1):85\u201390, doi: 10.1093\/jac\/dkm445","journal-title":"J Antimicrob Chemother"},{"key":"675_CR26","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/jac\/48.1.143","volume":"48","author":"AP Johnson","year":"2001","unstructured":"Johnson AP, Aucken HM, Cavendish S, Ganner M, Wale MCJ, Warner M, UK EARSS participants et al (2001) Dominance of EMRSA-15 and -16 among MRSA causing nosocomial bacteraemia in the UK: analysis of isolates from the European Antimicrobial Resistance Surveillance System (EARSS). J Antimicrob Chemother 48:143\u2013144, doi: 10.1093\/jac\/48.1.143","journal-title":"J Antimicrob Chemother"},{"issue":"10","key":"675_CR27","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1086\/501707","volume":"21","author":"LA Selvey","year":"2000","unstructured":"Selvey LA, Whitby M, Johnson B (2000) Nosocomial methicillin-resistant Staphylococcus aureus bacteremia: is it any worse than nosocomial methicillin-sensitive Staphylococcus aureus bacteremia? Infect Control Hosp Epidemiol 21(10):645\u2013648, doi: 10.1086\/501707","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"2","key":"675_CR28","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1086\/313650","volume":"30","author":"A Soriano","year":"2000","unstructured":"Soriano A, Mart\u00ednez JA, Mensa J, Marco F, Almela M, Moreno-Mart\u00ednez A et al (2000) Pathogenic significance of methicillin resistance for patients with Staphylococcus aureus bacteremia. Clin Infect Dis 30(2):368\u2013373, doi: 10.1086\/313650","journal-title":"Clin Infect Dis"},{"issue":"2","key":"675_CR29","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.diagmicrobio.2005.02.007","volume":"52","author":"TP Lodise","year":"2005","unstructured":"Lodise TP, McKinnon PS (2005) Clinical and economic impact of methicillin resistance in patients with Staphylococcus aureus bacteremia. Diagn Microbiol Infect Dis 52(2):113\u2013122, doi: 10.1016\/j.diagmicrobio.2005.02.007","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"6","key":"675_CR30","first-page":"288","volume":"6","author":"L Oliveira Conterno de","year":"2002","unstructured":"de Oliveira Conterno L, Wey SB, Castelo A (2002) Staphylococcus aureus bacteremia: comparison of two periods and a predictive model of mortality. Braz J Infect Dis 6(6):288\u2013297, doi: 10.1590\/S1413-86702002000600004","journal-title":"Braz J Infect Dis"},{"issue":"1","key":"675_CR31","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0953-6205(01)00189-3","volume":"13","author":"D Talon","year":"2002","unstructured":"Talon D, Woronoff-Lemsi MC, Limat S, Bertrand X, Chatillon M, Gil H et al (2002) The impact of resistance to methicillin in Staphylococcus aureus bacteremia on mortality. Eur J Intern Med 13(1):31\u201336, doi: 10.1016\/S0953-6205(01)00189-3","journal-title":"Eur J Intern Med"},{"issue":"2","key":"675_CR32","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jhin.2006.09.022","volume":"65","author":"I Das","year":"2007","unstructured":"Das I, O\u2019Connell N, Lambert P (2007) Epidemiology, clinical and laboratory characteristics of Staphylococcus aureus bacteraemia in a university hospital in UK. J Hosp Infect 65(2):117\u2013123, doi: 10.1016\/j.jhin.2006.09.022","journal-title":"J Hosp Infect"},{"issue":"3","key":"675_CR33","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1086\/512627","volume":"28","author":"S Shurland","year":"2007","unstructured":"Shurland S, Zhan M, Bradham DD, Roghmann MC (2007) Comparison of mortality risk associated with bacteremia due to methicillin-resistant and methicillin-susceptible Staphylococcus aureus. Infect Control Hosp Epidemiol 28(3):273\u2013279, doi: 10.1086\/512627","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"4","key":"675_CR34","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jhin.2005.10.001","volume":"62","author":"JA Karas","year":"2006","unstructured":"Karas JA, Enoch DA, Emery MM (2006) Community-onset healthcare-associated MRSA bacteraemia in a district general hospital. J Hosp Infect 62(4):480\u2013486, doi: 10.1016\/j.jhin.2005.10.001","journal-title":"J Hosp Infect"},{"issue":"7562","key":"675_CR35","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1136\/bmj.38834.421713.2F","volume":"333","author":"DH Wyllie","year":"2006","unstructured":"Wyllie DH, Crook DW, Peto TE (2006) Mortality after Staphylococcus aureus bacteraemia in two hospitals in Oxfordshire, 1997\u20132003: cohort study. BMJ 333(7562):281, doi: 10.1136\/bmj.38834.421713.2F","journal-title":"BMJ"},{"issue":"11","key":"675_CR36","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1086\/379321","volume":"37","author":"M Melzer","year":"2003","unstructured":"Melzer M, Eykyn SJ, Gransden WR, Chinn S (2003) Is methicillin-resistant Staphylococcus aureus more virulent than methicillin-susceptible S. aureus? A comparative cohort study of British patients with nosocomial infection and bacteremia. Clin Infect Dis 37(11):1453\u20131460, doi: 10.1086\/379321","journal-title":"Clin Infect Dis"},{"issue":"2","key":"675_CR37","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1378\/chest.125.2.607","volume":"125","author":"S Osmon","year":"2004","unstructured":"Osmon S, Ward S, Fraser VJ, Kollef MH (2004) Hospital mortality for patients with bacteremia due to Staphylococcus aureus or Pseudomonas aeruginosa. Chest 125(2):607\u2013616, doi: 10.1378\/chest.125.2.607","journal-title":"Chest"},{"issue":"4","key":"675_CR38","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/jac\/dkl017","volume":"57","author":"CG Gemmell","year":"2006","unstructured":"Gemmell CG, Edwards DI, Fraise AP, Gould FK, Ridgway GL, Warren RE (2006) Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK. J Antimicrob Chemother 57(4):589\u2013608, doi: 10.1093\/jac\/dkl017","journal-title":"J Antimicrob Chemother"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-008-0675-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-008-0675-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-008-0675-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T09:34:12Z","timestamp":1559122452000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-008-0675-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,9]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["675"],"URL":"https:\/\/doi.org\/10.1007\/s10096-008-0675-3","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,9]]}}}