{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:10:13Z","timestamp":1792253413177,"version":"4.4.0"},"reference-count":70,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2010,9,19]],"date-time":"2010-09-19T00:00:00Z","timestamp":1284854400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1007\/s10096-010-1049-1","type":"journal-article","created":{"date-parts":[[2010,9,18]],"date-time":"2010-09-18T18:10:07Z","timestamp":1284833407000},"page":"1465-1473","source":"Crossref","is-referenced-by-count":153,"title":["Assessment of splenic function"],"prefix":"10.1007","volume":"29","author":[{"given":"A. P. N. A.","family":"de Porto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. J. J.","family":"Lammers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. J.","family":"Bennink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I. J. M.","family":"ten Berge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Speelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. B. L.","family":"Hoekstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,9,19]]},"reference":[{"key":"1049_CR1","doi-asserted-by":"publisher","first-page":"33N","DOI":"10.1016\/0002-9343(90)90259-G","volume":"88","author":"B Styrt","year":"1990","unstructured":"Styrt B (1990) Infection associated with asplenia: risks, mechanisms, and prevention. Am J Med 88:33N\u201342N","journal-title":"Am J Med"},{"key":"1049_CR2","first-page":"285","volume":"1","author":"DB Singer","year":"1973","unstructured":"Singer DB (1973) Postsplenectomy sepsis. Perspect Pediatr Pathol 1:285\u2013311","journal-title":"Perspect Pediatr Pathol"},{"key":"1049_CR3","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1002\/bjs.1800780904","volume":"78","author":"RJ Holdsworth","year":"1991","unstructured":"Holdsworth RJ, Irving AD, Cuschieri A (1991) Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg 78:1031\u20131038","journal-title":"Br J Surg"},{"key":"1049_CR4","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1053\/jinf.2001.0904","volume":"43","author":"N Bisharat","year":"2001","unstructured":"Bisharat N, Omari H, Lavi I, Raz R (2001) Risk of infection and death among post-splenectomy patients. J Infect 43:182\u2013186","journal-title":"J Infect"},{"key":"1049_CR5","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3748\/wjg.14.176","volume":"14","author":"T Okabayashi","year":"2008","unstructured":"Okabayashi T, Hanazaki K (2008) Overwhelming postsplenectomy infection syndrome in adults\u2014a clinically preventable disease. World J Gastroenterol 14:176\u2013179","journal-title":"World J Gastroenterol"},{"key":"1049_CR6","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1002\/1096-8652(200009)65:1<25::AID-AJH4>3.0.CO;2-8","volume":"65","author":"ML Brigden","year":"2000","unstructured":"Brigden ML, Pattullo A, Brown G (2000) Pneumococcal vaccine administration associated with splenectomy: the need for improved education, documentation, and the use of a practical checklist. Am J Hematol 65:25\u201329","journal-title":"Am J Hematol"},{"key":"1049_CR7","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/S0891-5520(05)70322-6","volume":"10","author":"AM Lynch","year":"1996","unstructured":"Lynch AM, Kapila R (1996) Overwhelming postsplenectomy infection. Infect Dis Clin North Am 10:693\u2013707","journal-title":"Infect Dis Clin North Am"},{"key":"1049_CR8","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1002\/bjs.1800780626","volume":"78","author":"GL Cullingford","year":"1991","unstructured":"Cullingford GL, Watkins DN, Watts AD, Mallon DF (1991) Severe late postsplenectomy infection. Br J Surg 78:716\u2013721","journal-title":"Br J Surg"},{"key":"1049_CR9","first-page":"3865","volume-title":"Principles and practice of infectious diseases","author":"LI Lutwick","year":"2010","unstructured":"Lutwick LI (2010) Infections in asplenic patients. In: Mandell GJ, Bennett JE, Raphael D (eds) Principles and practice of infectious diseases, 7th edn. Churchill Livingstone, Elsevier, pp 3865\u20133873","edition":"7"},{"key":"1049_CR10","first-page":"430","volume":"7028","author":"Working Party of the British Committee for Standards in Haematology Clinical Haematology Task Force","year":"1996","unstructured":"Working Party of the British Committee for Standards in Haematology Clinical Haematology Task Force. (1996) Guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen. BMJ 7028:430\u2013434","journal-title":"BMJ"},{"key":"1049_CR11","doi-asserted-by":"crossref","first-page":"440","DOI":"10.7861\/clinmedicine.2-5-440","volume":"2","author":"JM Davies","year":"2002","unstructured":"Davies JM, Barnes R, Milligan D (2002) Update of guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen. Clin Med 2:440\u2013443","journal-title":"Clin Med"},{"key":"1049_CR12","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1002\/bjs.6106","volume":"95","author":"EG Mourtzoukou","year":"2008","unstructured":"Mourtzoukou EG, Pappas G, Peppas G, Falagas ME (2008) Vaccination of asplenic or hyposplenic adults. Br J Surg 95:273\u2013280","journal-title":"Br J Surg"},{"key":"1049_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/10245330600938422","volume":"12","author":"BM William","year":"2007","unstructured":"William BM, Corazza GR (2007) Hyposplenism: a comprehensive review. I. Basic concepts and causes. Hematology 12:1\u201313","journal-title":"Hematology"},{"key":"1049_CR14","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1126\/science.173.3993.251","volume":"173","author":"B Schnitzer","year":"1971","unstructured":"Schnitzer B, Rucknagel DL, Spencer HH, Aikawa M (1971) Erythrocytes: pits and vacuoles as seen with transmission and scanning electron microscopy. Science 173:251\u2013252","journal-title":"Science"},{"key":"1049_CR15","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1182\/blood.V36.5.566.566","volume":"36","author":"CP Holroyde","year":"1970","unstructured":"Holroyde CP, Gardner FH (1970) Acquisition of autophagic vacuoles by human erythrocytes. Physiological role of the spleen. Blood 36:566\u2013575","journal-title":"Blood"},{"key":"1049_CR16","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1097\/00007611-198708000-00016","volume":"80","author":"DC Doll","year":"1987","unstructured":"Doll DC, List AF, Yarbro JW (1987) Functional hyposplenism. South Med J 80:999\u20131006","journal-title":"South Med J"},{"key":"1049_CR17","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1093\/ajcp\/32.6.526","volume":"32","author":"RL Lipson","year":"1959","unstructured":"Lipson RL, Bayrd ED, Watkins CH (1959) The postsplenectomy blood picture. Am J Clin Pathol 32:526\u2013532","journal-title":"Am J Clin Pathol"},{"key":"1049_CR18","first-page":"113","volume":"31","author":"W Damshek","year":"1955","unstructured":"Damshek W (1955) Hypersplenism. Bull NY Acad Med 31:113\u2013136","journal-title":"Bull NY Acad Med"},{"key":"1049_CR19","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.exphem.2006.09.013","volume":"35","author":"VL Harrod","year":"2007","unstructured":"Harrod VL, Howard TA, Zimmerman SA, Dertinger SD, Ware RE (2007) Quantitative analysis of Howell-Jolly bodies in children with sickle cell disease. Exp Hematol 35:179\u2013183","journal-title":"Exp Hematol"},{"key":"1049_CR20","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1056\/NEJM196909042811002","volume":"281","author":"CP Holroyde","year":"1969","unstructured":"Holroyde CP, Oski FA, Gardner FH (1969) The \"pocked\" erythrocyte. Red-cell surface alterations in reticuloendothelial immaturity of the neonate. N Engl J Med 281:516\u2013520","journal-title":"N Engl J Med"},{"key":"1049_CR21","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1002\/ajh.2830270407","volume":"27","author":"WH Reinhart","year":"1988","unstructured":"Reinhart WH, Chien S (1988) Red cell vacuoles: their size and distribution under normal conditions and after splenectomy. Am J Hematol 27:265\u2013271","journal-title":"Am J Hematol"},{"key":"1049_CR22","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1042\/cs0600109","volume":"60","author":"GR Corazza","year":"1981","unstructured":"Corazza GR, Bullen AW, Hall R, Robinson PJ, Losowsky MS (1981) Simple method of assessing splenic function in coeliac disease. Clin Sci (Lond) 60:109\u2013113","journal-title":"Clin Sci (Lond)"},{"key":"1049_CR23","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1182\/blood.V47.2.183.183","volume":"47","author":"JT Casper","year":"1976","unstructured":"Casper JT, Koethe S, Rodey GE, Thatcher LG (1976) A new method for studying splenic reticuloendothelial dysfunction in sickle cell disease patients and its clinical application: a brief report. Blood 47:183\u2013188","journal-title":"Blood"},{"key":"1049_CR24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1542\/peds.76.3.392","volume":"76","author":"HA Pearson","year":"1985","unstructured":"Pearson HA, Gallagher D, Chilcote R, Sullivan E, Wilimas J, Espeland M, Ritchey AK (1985) Developmental pattern of splenic dysfunction in sickle cell disorders. Pediatrics 76:392\u2013397","journal-title":"Pediatrics"},{"key":"1049_CR25","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1182\/blood.V85.8.2238.bloodjournal8582238","volume":"85","author":"PA Lane","year":"1995","unstructured":"Lane PA, O'Connell JL, Lear JL, Rogers ZR, Woods GM, Hassell KL, Wethers DL, Luckey DW, Buchanan GR (1995) Functional asplenia in hemoglobin SC disease. Blood 85:2238\u20132244","journal-title":"Blood"},{"key":"1049_CR26","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1136\/bmj.289.6449.861","volume":"289","author":"GR Corazza","year":"1984","unstructured":"Corazza GR, Tarozzi C, Vaira D, Frisoni M, Gasbarrini G (1984) Return of splenic function after splenectomy: how much tissue is needed? Br Med J (Clin Res Ed) 289:861\u2013864","journal-title":"Br Med J (Clin Res Ed)"},{"key":"1049_CR27","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1093\/ajcp\/105.5.548","volume":"105","author":"KT Tham","year":"1996","unstructured":"Tham KT, Teague MW, Howard CA, Chen SY (1996) A simple splenic reticuloendothelial function test: counting erythrocytes with argyrophilic inclusions. Am J Clin Pathol 105:548\u2013552","journal-title":"Am J Clin Pathol"},{"key":"1049_CR28","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1038\/nri1669","volume":"5","author":"RE Mebius","year":"2005","unstructured":"Mebius RE, Kraal G (2005) Structure and function of the spleen. Nat Rev Immunol 5:606\u2013616","journal-title":"Nat Rev Immunol"},{"key":"1049_CR29","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1111\/j.1365-2362.2006.01626.x","volume":"36","author":"M Langeveld","year":"2006","unstructured":"Langeveld M, Gamadia LE, ten Berge IJ (2006) T-lymphocyte subset distribution in human spleen. Eur J Clin Invest 36:250\u2013256","journal-title":"Eur J Clin Invest"},{"key":"1049_CR30","doi-asserted-by":"publisher","first-page":"2962","DOI":"10.1002\/eji.200526216","volume":"35","author":"EA Koppel","year":"2005","unstructured":"Koppel EA, Wieland CW, van den Berg VC, Litjens M, Florquin S, van Kooyk Y, van der Poll T, Geijtenbeek TB (2005) Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection. Eur J Immunol 35:2962\u20132969","journal-title":"Eur J Immunol"},{"key":"1049_CR31","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1084\/jem.20022020","volume":"197","author":"S Kruetzmann","year":"2003","unstructured":"Kruetzmann S, Rosado MM, Weber H, Germing U, Tournilhac O, Peter HH, Berner R, Peters A, Boehm T, Plebani A, Quinti I, Carsetti R (2003) Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen. J Exp Med 197:939\u2013945","journal-title":"J Exp Med"},{"key":"1049_CR32","doi-asserted-by":"publisher","first-page":"3647","DOI":"10.1182\/blood-2004-01-0346","volume":"104","author":"S Weller","year":"2004","unstructured":"Weller S, Braun MC, Tan BK, Rosenwald A, Cordier C, Conley ME, Plebani A, Kumararatne DS, Bonnet D, Tournilhac O, Tchernia G, Steiniger B, Staudt LM, Casanova JL, Reynaud CA, Weill JC (2004) Human blood IgM \u201cmemory\u201d B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood 104:3647\u20133654","journal-title":"Blood"},{"key":"1049_CR33","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.it.2004.11.004","volume":"26","author":"S Weller","year":"2005","unstructured":"Weller S, Reynaud CA, Weill JC (2005) Vaccination against encapsulated bacteria in humans: paradoxes. Trends Immunol 26:85\u201389","journal-title":"Trends Immunol"},{"key":"1049_CR34","doi-asserted-by":"crossref","first-page":"5596","DOI":"10.4049\/jimmunol.164.11.5596","volume":"164","author":"M Dono","year":"2000","unstructured":"Dono M, Zupo S, Leanza N, Melioli G, Fogli M, Melagrana A, Chiorazzi N, Ferrarini M (2000) Heterogeneity of tonsillar subepithelial B lymphocytes, the splenic marginal zone equivalents. J Immunol 164:5596\u20135604","journal-title":"J Immunol"},{"key":"1049_CR35","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/S0167-5699(98)01308-5","volume":"19","author":"J Spencer","year":"1998","unstructured":"Spencer J, Perry ME, Dunn-Walters DK (1998) Human marginal-zone B cells. Immunol Today 19:421\u2013426","journal-title":"Immunol Today"},{"key":"1049_CR36","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/1074-7613(95)90048-9","volume":"2","author":"YJ Liu","year":"1995","unstructured":"Liu YJ, Barthelemy C, de Bouteiller O, Arpin C, Durand I, Banchereau J (1995) Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2. Immunity 2:239\u2013248","journal-title":"Immunity"},{"key":"1049_CR37","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1111\/j.1572-0241.2005.41939.x","volume":"100","author":"A Sabatino Di","year":"2005","unstructured":"Di Sabatino A, Rosado MM, Ciccocioppo R, Cazzola P, Morera R, Corazza GR, Carsetti R (2005) Depletion of immunoglobulin M memory B cells is associated with splenic hypofunction in inflammatory bowel disease. Am J Gastroenterol 100:1788\u20131795","journal-title":"Am J Gastroenterol"},{"key":"1049_CR38","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1136\/bmj.2.6102.1574","volume":"2","author":"Z Spirer","year":"1977","unstructured":"Spirer Z, Zakuth V, Diamant S, Mondorf W, Stefanescu T, Stabinsky Y, Fridkin M (1977) Decreased tuftsin concentrations in patients who have undergone splenectomy. Br Med J 2:1574\u20131576","journal-title":"Br Med J"},{"key":"1049_CR39","first-page":"1230","volume":"33","author":"A Constantopoulos","year":"1973","unstructured":"Constantopoulos A, Likhite V, Crosby WH, Najjar VA (1973) Phagocytic activity of the leukemic cell and its response to the phagocytosis-stimulating tetrapeptide, tuftsin. Cancer Res 33:1230\u20131234","journal-title":"Cancer Res"},{"key":"1049_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1749-6632.1983.tb37086.x","volume":"419","author":"VA Najjar","year":"1983","unstructured":"Najjar VA (1983) Tuftsin, a natural activator of phagocyte cells: an overview. Ann NY Acad Sci 419:1\u201311","journal-title":"Ann NY Acad Sci"},{"key":"1049_CR41","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1136\/adc.55.7.566","volume":"55","author":"Z Spirer","year":"1980","unstructured":"Spirer Z, Weisman Y, Zakuth V, Fridkin M, Bogair N (1980) Decreased serum tuftsin concentrations in sickle cell disease. Arch Dis Child 55:566\u2013567","journal-title":"Arch Dis Child"},{"key":"1049_CR42","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1111\/j.1572-0241.1999.00865.x","volume":"94","author":"GR Corazza","year":"1999","unstructured":"Corazza GR, Zoli G, Di SA, Ciccocioppo R, Gasbarrini G (1999) A reassessment of splenic hypofunction in celiac disease. Am J Gastroenterol 94:391\u2013397","journal-title":"Am J Gastroenterol"},{"key":"1049_CR43","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1148\/radiology.155.3.4039827","volume":"155","author":"P Ambriz","year":"1985","unstructured":"Ambriz P, Munoz R, Quintanar E, Sigler L, Aviles A, Pizzuto J (1985) Accessory spleen compromising response to splenectomy for idiopathic thrombocytopenic purpura. Radiology 155:793\u2013796","journal-title":"Radiology"},{"key":"1049_CR44","first-page":"2286","volume":"32","author":"MD Massey","year":"1991","unstructured":"Massey MD, Stevens JS (1991) Residual spleen found on denatured red blood cell scan following negative colloid scans. J Nucl Med 32:2286\u20132287","journal-title":"J Nucl Med"},{"key":"1049_CR45","first-page":"559","volume":"24","author":"D Nostrand Van","year":"1983","unstructured":"Van Nostrand D, Corley JH, Kyle RW, Stotler RE (1983) Value of selective spleen scintigraphy when liver\/spleen image shows equivocal spleen defects: concise communication. J Nucl Med 24:559\u2013562","journal-title":"J Nucl Med"},{"key":"1049_CR46","first-page":"13","volume":"21","author":"T Ramchandran","year":"1980","unstructured":"Ramchandran T, Margouleff D, Atkins H (1980) Spleen scanning in humans with Tc-99m-labeled erythrocytes: concise communication. J Nucl Med 21:13\u201316","journal-title":"J Nucl Med"},{"key":"1049_CR47","first-page":"413","volume":"21","author":"RR Armas","year":"1980","unstructured":"Armas RR, Thakur ML, Gottschalk A (1980) A simplified method of selective spleen scintigraphy with Tc-99m-labeled erythrocytes: clinical applications. Concise communication. J Nucl Med 21:413\u2013416","journal-title":"J Nucl Med"},{"key":"1049_CR48","first-page":"209","volume":"23","author":"CP Ehrlich","year":"1982","unstructured":"Ehrlich CP, Papanicolaou N, Treves S, Hurwitz RA, Richards P (1982) Splenic scintigraphy using Tc-99m-labeled heat-denatured red blood cells in pediatric patients: concise communication. J Nucl Med 23:209\u2013213","journal-title":"J Nucl Med"},{"key":"1049_CR49","first-page":"966","volume-title":"Nuclear medicine","author":"WB Hladik","year":"1996","unstructured":"Hladik WB, Norenberg JP (1996) Radiopharmaceuticals for liver and spleen imaging. In: Henkin RE, Boles MA, Dillehay GL et al (eds) Nuclear medicine. Mosby, Missouri, pp 966\u2013976"},{"key":"1049_CR50","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/S0001-2998(85)80004-0","volume":"15","author":"RR Armas","year":"1985","unstructured":"Armas RR (1985) Clinical studies with spleen-specific radiolabeled agents. Semin Nucl Med 15:260\u2013275","journal-title":"Semin Nucl Med"},{"key":"1049_CR51","first-page":"320","volume":"29","author":"A Owunwanne","year":"1988","unstructured":"Owunwanne A, Halkar R, Al-Rasheed A, Abubacker KC, Abdel-Dayem H (1988) Radionuclide imaging of the spleen with heat denatured technetium-99m RBC when the splenic reticuloendothelial system seems impaired. J Nucl Med 29:320\u2013323","journal-title":"J Nucl Med"},{"key":"1049_CR52","first-page":"481","volume":"36","author":"R Schmitz","year":"2010","unstructured":"Schmitz R, Hemayat E, Lammers AJJ, de Porto APNA, de Jong J, Bennink RJ (2010) Measurement of splenic function with heat-damaged red blood cells. Eur J Nucl Med Mol Imaging 36:481","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1049_CR53","doi-asserted-by":"crossref","first-page":"290","DOI":"10.4269\/ajtmh.2004.71.290","volume":"71","author":"M Demar","year":"2004","unstructured":"Demar M, Legrand E, Hommel D, Esterre P, Carme B (2004) Plasmodium falciparum malaria in splenectomized patients: two case reports in French Guiana and a literature review. Am J Trop Med Hyg 71:290\u2013293","journal-title":"Am J Trop Med Hyg"},{"key":"1049_CR54","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0308-2261(21)00129-6","volume":"6","author":"JE Pettit","year":"1977","unstructured":"Pettit JE (1977) Spleen function. Clin Haematol 6:639\u2013656","journal-title":"Clin Haematol"},{"key":"1049_CR55","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1097\/01.rlu.0000129117.55170.fd","volume":"29","author":"H Phom","year":"2004","unstructured":"Phom H, Kumar A, Tripathi M, Chandrashekar N, Choudhry VP, Malhotra A, Bal CS (2004) Comparative evaluation of Tc-99m-heat-denatured RBC and Tc-99m-anti-D IgG opsonized RBC spleen planar and SPECT scintigraphy in the detection of accessory spleen in postsplenectomy patients with chronic idiopathic thrombocytopenic purpura. Clin Nucl Med 29:403\u2013409","journal-title":"Clin Nucl Med"},{"key":"1049_CR56","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1259\/0007-1285-53-630-532","volume":"53","author":"PJ Robinson","year":"1980","unstructured":"Robinson PJ, Bullen AW, Hall R, Brown RC, Baxter P, Losowsky MS (1980) Splenic size and function in adult coeliac disease. Br J Radiol 53:532\u2013537","journal-title":"Br J Radiol"},{"key":"1049_CR57","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1136\/gut.19.1.56","volume":"19","author":"RC Smart","year":"1978","unstructured":"Smart RC, Ryan FP, Holdworth CD, Preston FE (1978) Relationship between splenic size and splenic function. Gut 19:56\u201359","journal-title":"Gut"},{"key":"1049_CR58","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1742-1241.1983.tb08454.x","volume":"37","author":"DA Robertson","year":"1983","unstructured":"Robertson DA, Bullen AW, Hall R, Losowsky MS (1983) Blood film appearances in the hyposplenism of coeliac disease. Br J Clin Pract 37:19\u201322","journal-title":"Br J Clin Pract"},{"key":"1049_CR59","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1160\/nukmed-0063","volume":"46","author":"M Gotthardt","year":"2007","unstructured":"Gotthardt M, Broker S, Schlieck A, Bauhofer A, Herbst B, Behe M, Corstens FH, Behr TM, Gorg C (2007) Scintigraphy with 99mTc-labeled heat-altered erythrocytes in diagnosing hyposplenia: prospective comparison to 99mTc-labeled colloids and colour-coded duplex ultrasonography. Nuklearmediziner 46:135\u2013140","journal-title":"Nuklearmediziner"},{"key":"1049_CR60","first-page":"81","volume":"28","author":"MA Zago","year":"1986","unstructured":"Zago MA, Costa FF, Covas DT, Figueiredo MS, Bottura C (1986) Discrepancy between pit counting and spleen function tests in nutritional anemias and hemoglobinopathy C. Nouv Rev Fr H\u00e9matol 28:81\u201384","journal-title":"Nouv Rev Fr H\u00e9matol"},{"key":"1049_CR61","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1136\/gut.19.1.50","volume":"19","author":"FP Ryan","year":"1978","unstructured":"Ryan FP, Smart RC, Holdsworth CD, Preston FE (1978) Hyposplenism in inflammatory bowel disease. Gut 19:50\u201355","journal-title":"Gut"},{"key":"1049_CR62","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1111\/j.1365-2257.1990.tb00037.x","volume":"12","author":"GR Corazza","year":"1990","unstructured":"Corazza GR, Ginaldi L, Zoli G, Frisoni M, Lalli G, Gasbarrini G, Quaglino D (1990) Howell-Jolly body counting as a measure of splenic function. A reassessment. Clin Lab Haematol 12:269\u2013275","journal-title":"Clin Lab Haematol"},{"key":"1049_CR63","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/S1542-3565(05)00982-1","volume":"4","author":"A Sabatino Di","year":"2006","unstructured":"Di Sabatino A, Rosado MM, Cazzola P, Riboni R, Biagi F, Carsetti R, Corazza GR (2006) Splenic hypofunction and the spectrum of autoimmune and malignant complications in celiac disease. Clin Gastroenterol Hepatol 4:179\u2013186","journal-title":"Clin Gastroenterol Hepatol"},{"key":"1049_CR64","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1056\/NEJM197008132830703","volume":"283","author":"HA Pearson","year":"1970","unstructured":"Pearson HA, Cornelius EA, Schwartz AD, Zelson JH, Wolfson SL, Spencer RP (1970) Transfusion-reversible functional asplenia in young children with sickle-cell anemia. N Engl J Med 283:334\u2013337","journal-title":"N Engl J Med"},{"key":"1049_CR65","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1182\/blood.V81.4.1102.bloodjournal8141102","volume":"81","author":"A Ferster","year":"1993","unstructured":"Ferster A, Bujan W, Corazza F, Devalck C, Fondu P, Toppet M, Verhas M, Sariban E (1993) Bone marrow transplantation corrects the splenic reticuloendothelial dysfunction in sickle cell anemia. Blood 81:1102\u20131105","journal-title":"Blood"},{"key":"1049_CR66","first-page":"463","volume":"50","author":"KR Palmer","year":"1981","unstructured":"Palmer KR, Sherriff SB, Holdsworth CD, Ryan FP (1981) Further experience of hyposplenism in inflammatory bowel disease. Q J Med 50:463\u2013471","journal-title":"Q J Med"},{"key":"1049_CR67","doi-asserted-by":"crossref","first-page":"40","DOI":"10.7326\/0003-4819-96-1-40","volume":"96","author":"AM Dillon","year":"1982","unstructured":"Dillon AM, Stein HB, English RA (1982) Splenic atrophy in systemic lupus erythematosus. Ann Intern Med 96:40\u201343","journal-title":"Ann Intern Med"},{"key":"1049_CR68","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/S0268-960X(03)00003-1","volume":"17","author":"RL Nagel","year":"2003","unstructured":"Nagel RL, Fabry ME, Steinberg MH (2003) The paradox of hemoglobin SC disease. Blood Rev 17:167\u2013178","journal-title":"Blood Rev"},{"key":"1049_CR69","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/RLU.0b013e31815f238e","volume":"33","author":"A Mestre-Fusco","year":"2008","unstructured":"Mestre-Fusco A, Aguade-Bruix S, Zuccarino F, Boronat-Ferrater M, Rossi S, Andreu J (2008) Sickle cell anemia and functioning splenic tissue: correlation of scintigraphic findings and CT. Clin Nucl Med 33:137\u2013139","journal-title":"Clin Nucl Med"},{"key":"1049_CR70","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1042\/cs0650297","volume":"65","author":"MA Zago","year":"1983","unstructured":"Zago MA, Bottura C (1983) Splenic function in sickle-cell diseases. Clin Sci (Lond) 65:297\u2013302","journal-title":"Clin Sci (Lond)"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-010-1049-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-010-1049-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-010-1049-1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-010-1049-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,3]],"date-time":"2023-06-03T11:26:57Z","timestamp":1685791617000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-010-1049-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,19]]},"references-count":70,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["1049"],"URL":"https:\/\/doi.org\/10.1007\/s10096-010-1049-1","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,19]]}}}