{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T07:32:27Z","timestamp":1764401547822},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2011,10,9]],"date-time":"2011-10-09T00:00:00Z","timestamp":1318118400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1007\/s10096-011-1432-6","type":"journal-article","created":{"date-parts":[[2011,10,8]],"date-time":"2011-10-08T11:00:50Z","timestamp":1318071650000},"page":"1219-1224","source":"Crossref","is-referenced-by-count":42,"title":["Reemerging of enterovirus 71 in Taiwan: the age impact on disease severity"],"prefix":"10.1007","volume":"31","author":[{"given":"S.-M.","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.-S.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.-C.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.-Y.","family":"Lei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-R.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.-C.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,10,9]]},"reference":[{"key":"1432_CR1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1086\/520149","volume":"29","author":"SM Wang","year":"1999","unstructured":"Wang SM, Liu CC, Tseng HW, Wang JR, Huang CC, Chen YJ et al (1999) Clinical spectrum of enterovirus 71 infection in children in southern Taiwan, with an emphasis on neurological complications. Clin Infect Dis 29:184\u2013190","journal-title":"Clin Infect Dis"},{"key":"1432_CR2","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0163-4453(98)92076-X","volume":"37","author":"SM Wang","year":"1998","unstructured":"Wang SM, Liu CC, Yang YJ, Yang HB, Lin CH, Wang JR (1998) Fatal coxsackievirus B infection in early infancy characterized by fulminant hepatitis. J Infect 37:270\u2013273","journal-title":"J Infect"},{"key":"1432_CR3","first-page":"629","volume":"47","author":"Centers for Disease Control and Prevention (CDC)","year":"1998","unstructured":"Centers for Disease Control and Prevention (CDC) (1998) Deaths among children during an outbreak of hand, foot, and mouth disease\u2014Taiwan, Republic of China, April\u2013July 1998. MMWR Morb Mortal Wkly Rep 47:629\u2013632","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"1432_CR4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S1386-6532(00)00068-8","volume":"17","author":"CC Liu","year":"2000","unstructured":"Liu CC, Tseng HW, Wang SM, Wang JR, Su IJ (2000) An outbreak of enterovirus 71 infection in Taiwan, 1998: epidemiologic and clinical manifestations. J Clin Virol 17:23\u201330","journal-title":"J Clin Virol"},{"key":"1432_CR5","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1056\/NEJM199909233411301","volume":"341","author":"M Ho","year":"1999","unstructured":"Ho M, Chen ER, Hsu KH, Twu SJ, Chen KT, Tsai SF et al (1999) An epidemic of enterovirus 71 infection in Taiwan. Taiwan Enterovirus Epidemic Working Group. N Engl J Med 341:929\u2013935","journal-title":"N Engl J Med"},{"key":"1432_CR6","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1086\/511073","volume":"44","author":"MH Ooi","year":"2007","unstructured":"Ooi MH, Wong SC, Podin Y, Akin W, del Sel S, Mohan A et al (2007) Human enterovirus 71 disease in Sarawak, Malaysia: a prospective clinical, virological, and molecular epidemiological study. Clin Infect Dis 44:646\u2013656","journal-title":"Clin Infect Dis"},{"key":"1432_CR7","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1086\/521895","volume":"45","author":"CM P\u00e9rez-V\u00e9lez","year":"2007","unstructured":"P\u00e9rez-V\u00e9lez CM, Anderson MS, Robinson CC, McFarland EJ, Nix WA, Pallansch MA et al (2007) Outbreak of neurologic enterovirus type 71 disease: a diagnostic challenge. Clin Infect Dis 45:950\u2013957","journal-title":"Clin Infect Dis"},{"key":"1432_CR8","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0022-3476(98)70155-6","volume":"133","author":"LC Lum","year":"1998","unstructured":"Lum LC, Wong KT, Lam SK, Chua KB, Goh AY, Lim WL et al (1998) Fatal enterovirus 71 encephalomyelitis. J Pediatr 133:795\u2013798","journal-title":"J Pediatr"},{"key":"1432_CR9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1086\/318454","volume":"32","author":"PC McMinn","year":"2001","unstructured":"McMinn PC, Stratov I, Nagarajan L, Davis S (2001) Neurological manifestations of enterovirus 71 infection in children during an outbreak of hand, foot, and mouth disease in Western Australia. Clin Infect Dis 32:236\u2013242","journal-title":"Clin Infect Dis"},{"key":"1432_CR10","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3201\/eid1301.020112","volume":"9","author":"KP Chan","year":"2003","unstructured":"Chan KP, Goh KT, Chong CY, Teo ES, Lau G, Ling AE (2003) Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore. Emerg Infect Dis 9:78\u201385","journal-title":"Emerg Infect Dis"},{"key":"1432_CR11","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.3201\/eid1311.070632","volume":"13","author":"P Tu Van","year":"2007","unstructured":"Van Tu P, Thao NTT, Perera D, Huu TK, Tien NT, Thuong TC et al (2007) Epidemiologic and virologic investigation of hand, foot, and mouth disease, southern Vietnam, 2005. Emerg Infect Dis 13:1733\u20131741","journal-title":"Emerg Infect Dis"},{"key":"1432_CR12","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jcv.2010.07.009","volume":"49","author":"LX Mao","year":"2010","unstructured":"Mao LX, Wu B, Bao WX, Han FA, Xu L, Ge QJ et al (2010) Epidemiology of hand, foot, and mouth disease and genotype characterization of enterovirus 71 in Jiangsu, China. J Clin Virol 49:100\u2013104","journal-title":"J Clin Virol"},{"key":"1432_CR13","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1086\/376998","volume":"188","author":"SM Wang","year":"2003","unstructured":"Wang SM, Lei HY, Huang KJ, Wu JM, Wang JR, Yu CK et al (2003) Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema. J Infect Dis 188:564\u2013570","journal-title":"J Infect Dis"},{"key":"1432_CR14","doi-asserted-by":"crossref","first-page":"e1785","DOI":"10.1542\/peds.2006-1547","volume":"118","author":"MC Huang","year":"2006","unstructured":"Huang MC, Wang SM, Hsu YW, Lin HC, Chi CY, Liu CC (2006) Long-term cognitive and motor deficits after enterovirus 71 brainstem encephalitis in children. Pediatrics 118:e1785\u2013e1788","journal-title":"Pediatrics"},{"key":"1432_CR15","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/jmv.2210","volume":"67","author":"CY Lu","year":"2002","unstructured":"Lu CY, Lee CY, Kao CL, Shao WY, Lee PI, Twu SJ et al (2002) Incidence and case-fatality rates resulting from the 1998 enterovirus 71 outbreak in Taiwan. J Med Virol 67:217\u2013223","journal-title":"J Med Virol"},{"key":"1432_CR16","doi-asserted-by":"crossref","first-page":"e244","DOI":"10.1542\/peds.2006-3331","volume":"120","author":"KT Chen","year":"2007","unstructured":"Chen KT, Chang HL, Wang ST, Cheng YT, Yang JY (2007) Epidemiologic features of hand-foot-mouth disease and herpangina caused by enterovirus 71 in Taiwan, 1998\u20132005. Pediatrics 120:e244\u2013e252","journal-title":"Pediatrics"},{"key":"1432_CR17","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1099\/vir.0.019695-0","volume":"91","author":"S Sanden van der","year":"2010","unstructured":"van der Sanden S, van der Avoort H, Lemey P, Uslu G, Koopmans M (2010) Evolutionary trajectory of the VP1 gene of human enterovirus 71 genogroup B and C viruses. J Gen Virol 91:1949\u20131958","journal-title":"J Gen Virol"},{"key":"1432_CR18","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0168-1702(00)00162-3","volume":"68","author":"SR Shih","year":"2000","unstructured":"Shih SR, Ho MS, Lin KH, Wu SL, Chen YT, Wu CN et al (2000) Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand, foot and mouth disease during an epidemic in Taiwan, 1998. Virus Res 68:127\u2013136","journal-title":"Virus Res"},{"key":"1432_CR19","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/S0140-6736(98)11032-2","volume":"354","author":"MJ Cardosa","year":"1999","unstructured":"Cardosa MJ, Krishnan S, Tio PH, Perera D, Wong SC (1999) Isolation of subgenus B adenovirus during a fatal outbreak of enterovirus 71-associated hand, foot, and mouth disease in Sibu, Sarawak. Lancet 354:987\u2013991","journal-title":"Lancet"},{"key":"1432_CR20","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1086\/591462","volume":"198","author":"SM Wang","year":"2008","unstructured":"Wang SM, Lei HY, Yu CK, Wang JR, Su IJ, Liu CC (2008) Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitis. J Infect Dis 198:1002\u20131006","journal-title":"J Infect Dis"},{"key":"1432_CR21","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3201\/eid1504.081550","volume":"15","author":"ST Luo","year":"2009","unstructured":"Luo ST, Chiang PS, Chao AS, Liou GY, Lin R, Lin TY et al (2009) Enterovirus 71 maternal antibodies in infants, Taiwan. Emerg Infect Dis 15:581\u2013584","journal-title":"Emerg Infect Dis"},{"key":"1432_CR22","doi-asserted-by":"crossref","first-page":"995","DOI":"10.3201\/eid0809.010397","volume":"8","author":"EE Ooi","year":"2002","unstructured":"Ooi EE, Phoon MC, Ishak B, Chan SH (2002) Seroepidemiology of human enterovirus 71, Singapore. Emerg Infect Dis 8:995\u2013997","journal-title":"Emerg Infect Dis"},{"key":"1432_CR23","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/rmv.405","volume":"13","author":"A Takada","year":"2003","unstructured":"Takada A, Kawaoka Y (2003) Antibody-dependent enhancement of viral infection: molecular mechanisms and in vivo implications. Rev Med Virol 13:387\u2013398","journal-title":"Rev Med Virol"},{"key":"1432_CR24","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/icb.1964.44","volume":"42","author":"RA Hawkes","year":"1964","unstructured":"Hawkes RA (1964) Enhancement of the infectivity of arboviruses by specific antisera produced in domestic fowls. Aust J Exp Biol Med Sci 42:465\u2013482","journal-title":"Aust J Exp Biol Med Sci"},{"key":"1432_CR25","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1084\/jem.146.1.201","volume":"146","author":"SB Halstead","year":"1977","unstructured":"Halstead SB, O\u2019Rourke EJ (1977) Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody. J Exp Med 146:201\u2013217","journal-title":"J Exp Med"},{"key":"1432_CR26","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1006\/viro.2000.0627","volume":"278","author":"P Palmer","year":"2000","unstructured":"Palmer P, Charley B, Rombaut B, Da\u00ebron M, Lebon P (2000) Antibody-dependent induction of type I interferons by poliovirus in human mononuclear blood cells requires the type II Fc gamma receptor (CD32). Virology 278:86\u201394","journal-title":"Virology"},{"key":"1432_CR27","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1006\/jmcc.2002.2087","volume":"34","author":"C Kishimoto","year":"2002","unstructured":"Kishimoto C, Kurokawa M, Ochiai H (2002) Antibody-mediated immune enhancement in coxsackievirus B3 myocarditis. J Mol Cell Cardiol 34:1227\u20131238","journal-title":"J Mol Cell Cardiol"},{"key":"1432_CR28","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1128\/CVI.00108-10","volume":"17","author":"SM Wang","year":"2010","unstructured":"Wang SM, Chen IC, Su LY, Huang KJ, Lei HY, Liu CC (2010) Enterovirus 71 infection of monocytes with antibody-dependent enhancement. Clin Vaccine Immunol 17:1517\u20131523","journal-title":"Clin Vaccine Immunol"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-011-1432-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-011-1432-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-011-1432-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T09:34:30Z","timestamp":1559122470000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-011-1432-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,9]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["1432"],"URL":"https:\/\/doi.org\/10.1007\/s10096-011-1432-6","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,9]]}}}