{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T23:12:09Z","timestamp":1784329929423,"version":"3.55.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2012,1,13]],"date-time":"2012-01-13T00:00:00Z","timestamp":1326412800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1007\/s10096-011-1519-0","type":"journal-article","created":{"date-parts":[[2012,1,11]],"date-time":"2012-01-11T23:15:31Z","timestamp":1326323731000},"page":"1901-1909","source":"Crossref","is-referenced-by-count":42,"title":["The epidemiology of the first described carbapenem-resistant Klebsiella pneumoniae outbreak in a tertiary care hospital in Saudi Arabia: how far do we go?"],"prefix":"10.1007","volume":"31","author":[{"given":"H. H.","family":"Balkhy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"El-Saed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Johani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Francis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. A.","family":"Al-Qahtani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. N.","family":"Al-Ahdal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. T.","family":"Altayeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Arabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Alothman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Sallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,1,13]]},"reference":[{"issue":"3","key":"1519_CR1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","volume":"20","author":"AM Queenan","year":"2007","unstructured":"Queenan AM, Bush K (2007) Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev 20(3):440\u2013458, table of contents","journal-title":"Clin Microbiol Rev"},{"issue":"4","key":"1519_CR2","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1128\/AAC.45.4.1151-1161.2001","volume":"45","author":"H Yigit","year":"2001","unstructured":"Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, Alberti S, Bush K, Tenover FC (2001) Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother 45(4):1151\u20131161","journal-title":"Antimicrob Agents Chemother"},{"issue":"12","key":"1519_CR3","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1086\/594129","volume":"29","author":"A Srinivasan","year":"2008","unstructured":"Srinivasan A, Patel JB (2008) Klebsiella pneumoniae carbapenemase-producing organisms: an ounce of prevention really is worth a pound of cure. Infect Control Hosp Epidemiol 29(12):1107\u20131109","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"2","key":"1519_CR4","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1128\/AAC.01053-06","volume":"51","author":"ZQ Wei","year":"2007","unstructured":"Wei ZQ, Du XX, Yu YS, Shen P, Chen YG, Li LJ (2007) Plasmid-mediated KPC-2 in a Klebsiella pneumoniae isolate from China. Antimicrob Agents Chemother 51(2):763\u2013765","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"1519_CR5","doi-asserted-by":"crossref","first-page":"4826","DOI":"10.1128\/JCM.43.9.4826-4829.2005","volume":"43","author":"T Naas","year":"2005","unstructured":"Naas T, Levy M, Hirschauer C, Marchandin H, Nordmann P (2005) Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia. J Clin Microbiol 43(9):4826\u20134829","journal-title":"J Clin Microbiol"},{"issue":"8","key":"1519_CR6","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1128\/AAC.00299-07","volume":"51","author":"A Leavitt","year":"2007","unstructured":"Leavitt A, Navon-Venezia S, Chmelnitsky I, Schwaber MJ, Carmeli Y (2007) Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital. Antimicrob Agents Chemother 51(8):3026\u20133029","journal-title":"Antimicrob Agents Chemother"},{"issue":"12","key":"1519_CR7","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1086\/592412","volume":"29","author":"G Patel","year":"2008","unstructured":"Patel G, Huprikar S, Factor SH, Jenkins SG, Calfee DP (2008) Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 29(12):1099\u20131106","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"11","key":"1519_CR8","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1086\/591861","volume":"29","author":"AI Hidron","year":"2008","unstructured":"Hidron AI, Edwards JR, Patel J, Horan TC, Sievert DM, Pollock DA, Fridkin SK; National Healthcare Safety Network Team; Participating National Healthcare Safety Network Facilities (2008) NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006\u20132007. Infect Control Hosp Epidemiol 29(11):996\u20131011","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"10","key":"1519_CR9","first-page":"256","volume":"58","author":"Centers for Disease Control and Prevention (CDC)","year":"2009","unstructured":"Centers for Disease Control and Prevention (CDC) (2009) Guidance for control of infections with carbapenem-resistant or carbapenemase-producing Enterobacteriaceae in acute care facilities. MMWR Morb Mortal Wkly Rep 58(10):256\u2013260","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"4","key":"1519_CR10","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S1473-3099(09)70054-4","volume":"9","author":"P Nordmann","year":"2009","unstructured":"Nordmann P, Cuzon G, Naas T (2009) The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 9(4):228\u2013236","journal-title":"Lancet Infect Dis"},{"key":"1519_CR11","unstructured":"Clinical and Laboratory Standards Institute (CLS) (2009) Performance standards for antimicrobial susceptibility testing. Nineteenth information supplement (M100-S19). CLSI, Wayne, PA"},{"issue":"3","key":"1519_CR12","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ijantimicag.2010.05.014","volume":"36","author":"J Cohen Stuart","year":"2010","unstructured":"Cohen Stuart J, Leverstein-Van Hall MA; Dutch Working Party on the Detection of Highly Resistant Microorganisms (2010) Guideline for phenotypic screening and confirmation of carbapenemases in Enterobacteriaceae. Int J Antimicrob Agents 36(3):205\u2013210","journal-title":"Int J Antimicrob Agents"},{"issue":"2","key":"1519_CR13","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.mimet.2009.05.007","volume":"78","author":"A Alaidan","year":"2009","unstructured":"Alaidan A, Bohol MF, Al-Thawadi SI, Al-Suwaine A, Al-Qahtani AA, Al-Ahdal MN (2009) Rapid PFGE method for fingerprinting of Serratia marcescens isolates. J Microbiol Methods 78(2):238\u2013241","journal-title":"J Microbiol Methods"},{"issue":"9","key":"1519_CR14","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1128\/JCM.33.9.2233-2239.1995","volume":"33","author":"FC Tenover","year":"1995","unstructured":"Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B (1995) Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 33(9):2233\u20132239","journal-title":"J Clin Microbiol"},{"issue":"6","key":"1519_CR15","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1086\/652528","volume":"31","author":"D Ben-David","year":"2010","unstructured":"Ben-David D, Maor Y, Keller N, Regev-Yochay G, Tal I, Shachar D, Zlotkin A, Smollan G, Rahav G (2010) Potential role of active surveillance in the control of a hospital-wide outbreak of carbapenem-resistant Klebsiella pneumoniae infection. Infect Control Hosp Epidemiol 31(6):620\u2013626","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"12","key":"1519_CR16","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1086\/345921","volume":"186","author":"MA Gardam","year":"2002","unstructured":"Gardam MA, Burrows LL, Kus JV, Brunton J, Low DE, Conly JM, Humar A (2002) Is surveillance for multidrug-resistant enterobacteriaceae an effective infection control strategy in the absence of an outbreak? J Infect Dis 186(12):1754\u20131760","journal-title":"J Infect Dis"},{"issue":"5","key":"1519_CR17","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1086\/596734","volume":"30","author":"S Kochar","year":"2009","unstructured":"Kochar S, Sheard T, Sharma R, Hui A, Tolentino E, Allen G, Landman D, Bratu S, Augenbraun M, Quale J (2009) Success of an infection control program to reduce the spread of carbapenem-resistant Klebsiella pneumoniae. Infect Control Hosp Epidemiol 30(5):447\u2013452","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"6","key":"1519_CR18","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1086\/588004","volume":"29","author":"C Laurent","year":"2008","unstructured":"Laurent C, Rodriguez-Villalobos H, Rost F, Strale H, Vincent JL, Deplano A, Struelens MJ, Byl B (2008) Intensive care unit outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae controlled by cohorting patients and reinforcing infection control measures. Infect Control Hosp Epidemiol 29(6):517\u2013524","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"4","key":"1519_CR19","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1086\/651097","volume":"31","author":"LS Munoz-Price","year":"2010","unstructured":"Munoz-Price LS, Hayden MK, Lolans K, Won S, Calvert K, Lin M, Stemer A, Weinstein RA (2010) Successful control of an outbreak of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae at a long-term acute care hospital. Infect Control Hosp Epidemiol 31(4):341\u2013347","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"2","key":"1519_CR20","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1128\/AAC.01114-07","volume":"52","author":"M Castanheira","year":"2008","unstructured":"Castanheira M, Sader HS, Deshpande LM, Fritsche TR, Jones RN (2008) Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. Antimicrob Agents Chemother 52(2):570\u2013573","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"1519_CR21","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/jac\/dki175","volume":"56","author":"S Bratu","year":"2005","unstructured":"Bratu S, Tolaney P, Karumudi U, Quale J, Mooty M, Nichani S, Landman D (2005) Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents. J Antimicrob Chemother 56(1):128\u2013132","journal-title":"J Antimicrob Chemother"},{"issue":"7","key":"1519_CR22","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s10096-010-0921-3","volume":"29","author":"A T\u00f3th","year":"2010","unstructured":"T\u00f3th A, Damjanova I, Pusk\u00e1s E, J\u00e1nv\u00e1ri L, Farkas M, Dob\u00e1k A, B\u00f6r\u00f6cz K, P\u00e1szti J (2010) Emergence of a colistin-resistant KPC-2-producing Klebsiella pneumoniae ST258 clone in Hungary. Eur J Clin Microbiol Infect Dis 29(7):765\u2013769","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"5","key":"1519_CR23","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1128\/JCM.02466-08","volume":"47","author":"J Lee","year":"2009","unstructured":"Lee J, Patel G, Huprikar S, Calfee DP, Jenkins SG (2009) Decreased susceptibility to polymyxin B during treatment for carbapenem-resistant Klebsiella pneumoniae infection. J Clin Microbiol 47(5):1611\u20131612","journal-title":"J Clin Microbiol"},{"issue":"Suppl 4","key":"1519_CR24","doi-asserted-by":"crossref","first-page":"S215","DOI":"10.1016\/S0924-8579(09)70005-6","volume":"32","author":"LR Peterson","year":"2008","unstructured":"Peterson LR (2008) A review of tigecycline\u2014the first glycylcycline. Int J Antimicrob Agents 32(Suppl 4):S215\u2013S222","journal-title":"Int J Antimicrob Agents"},{"issue":"10","key":"1519_CR25","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1086\/605922","volume":"30","author":"A Borer","year":"2009","unstructured":"Borer A, Saidel-Odes L, Riesenberg K, Eskira S, Peled N, Nativ R, Schlaeffer F, Sherf M (2009) Attributable mortality rate for carbapenem-resistant Klebsiella pneumoniae bacteremia. Infect Control Hosp Epidemiol 30(10):972\u2013976","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"3","key":"1519_CR26","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1128\/AAC.01020-07","volume":"52","author":"MJ Schwaber","year":"2008","unstructured":"Schwaber MJ, Klarfeld-Lidji S, Navon-Venezia S, Schwartz D, Leavitt A, Carmeli Y (2008) Predictors of carbapenem-resistant Klebsiella pneumoniae acquisition among hospitalized adults and effect of acquisition on mortality. Antimicrob Agents Chemother 52(3):1028\u20131033","journal-title":"Antimicrob Agents Chemother"},{"issue":"7","key":"1519_CR27","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1086\/598244","volume":"30","author":"K Hussein","year":"2009","unstructured":"Hussein K, Sprecher H, Mashiach T, Oren I, Kassis I, Finkelstein R (2009) Carbapenem resistance among Klebsiella pneumoniae isolates: risk factors, molecular characteristics, and susceptibility patterns. Infect Control Hosp Epidemiol 30(7):666\u2013671","journal-title":"Infect Control Hosp Epidemiol"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-011-1519-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-011-1519-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-011-1519-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T17:20:12Z","timestamp":1593537612000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-011-1519-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,13]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["1519"],"URL":"https:\/\/doi.org\/10.1007\/s10096-011-1519-0","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,13]]}}}