{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:43:55Z","timestamp":1790009035610,"version":"4.0.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2012,11,15]],"date-time":"2012-11-15T00:00:00Z","timestamp":1352937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1007\/s10096-012-1767-7","type":"journal-article","created":{"date-parts":[[2012,11,14]],"date-time":"2012-11-14T21:12:47Z","timestamp":1352927567000},"page":"437-447","source":"Crossref","is-referenced-by-count":11,"title":["Sustained and differential antibody responses to virulence proteins of Brucella melitensis during acute and chronic infections in human brucellosis"],"prefix":"10.1007","volume":"32","author":[{"given":"J.","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Ke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q.","family":"Zhen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,11,15]]},"reference":[{"issue":"2","key":"1767_CR1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3201\/eid0302.970219","volume":"3","author":"MJ Corbel","year":"1997","unstructured":"Corbel MJ (1997) Brucellosis: an overview. Emerg Infect Dis 3(2):213\u2013221. doi: 10.3201\/eid0302.970219","journal-title":"Emerg Infect Dis"},{"issue":"22","key":"1767_CR2","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1056\/NEJMra050570","volume":"352","author":"G Pappas","year":"2005","unstructured":"Pappas G, Akritidis N, Bosilkovski M, Tsianos E (2005) Brucellosis. N Engl J Med 352(22):2325\u20132336. doi: 10.1056\/NEJMra050570","journal-title":"N Engl J Med"},{"issue":"12","key":"1767_CR3","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.3201\/eid1612.091081","volume":"16","author":"WY Zhang","year":"2010","unstructured":"Zhang WY, Guo WD, Sun SH, Jiang JF, Sun HL, Li SL, Liu W, Cao WC (2010) Human brucellosis, Inner Mongolia, China. Emerg Infect Dis 16(12):2001\u20132003. doi: 10.3201\/eid1612.091081","journal-title":"Emerg Infect Dis"},{"issue":"10","key":"1767_CR4","doi-asserted-by":"crossref","first-page":"4813","DOI":"10.1021\/pr200619r","volume":"10","author":"L Liang","year":"2011","unstructured":"Liang L, Tan X, Juarez S, Villaverde H, Pablo J, Nakajima-Sasaki R, Gotuzzo E, Saito M, Hermanson G, Molina D, Felgner S, Morrow WJ, Liang X, Gilman RH, Davies DH, Tsolis RM, Vinetz JM, Felgner PL (2011) Systems biology approach predicts antibody signature associated with Brucella melitensis infection in humans. J Proteome Res 10(10):4813\u20134824. doi: 10.1021\/pr200619r","journal-title":"J Proteome Res"},{"issue":"1","key":"1767_CR5","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1600-065X.2010.01001.x","volume":"240","author":"SH Kaufmann","year":"2011","unstructured":"Kaufmann SH (2011) Intracellular pathogens: living in an extreme environment. Immunol Rev 240(1):5\u201310. doi: 10.1111\/j.1600-065X.2010.01001.x","journal-title":"Immunol Rev"},{"issue":"33","key":"1767_CR6","doi-asserted-by":"crossref","first-page":"14703","DOI":"10.1073\/pnas.1009080107","volume":"107","author":"S Kunnath-Velayudhan","year":"2010","unstructured":"Kunnath-Velayudhan S, Salamon H, Wang HY, Davidow AL, Molina DM, Huynh VT, Cirillo DM, Michel G, Talbot EA, Perkins MD, Felgner PL, Liang X, Gennaro ML (2010) Dynamic antibody responses to the Mycobacterium tuberculosis proteome. Proc Natl Acad Sci U S A 107(33):14703\u201314708. doi: 10.1073\/pnas.1009080107","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"1767_CR7","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1128\/JCM.05298-11","volume":"50","author":"AP Cannella","year":"2012","unstructured":"Cannella AP, Lin JC, Liang L, Atluri V, Gotuzzo E, Felgner PL, Tsolis RM, Vinetz JM (2012) Serial kinetics of the antibody response against the complete Brucella melitensis ORFeome in focal vertebral brucellosis. J Clin Microbiol 50(3):922\u2013926. doi: 10.1128\/JCM.05298-11","journal-title":"J Clin Microbiol"},{"key":"1767_CR8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fcimb.2012.00001","volume":"2","author":"AP Cannella","year":"2012","unstructured":"Cannella AP, Tsolis RM, Liang L, Felgner PL, Saito M, Sette A, Gotuzzo E, Vinetz JM (2012) Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. Front Cell Infect Microbiol 2:1. doi: 10.3389\/fcimb.2012.00001","journal-title":"Front Cell Infect Microbiol"},{"issue":"4","key":"1767_CR9","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1128\/JCM.00010-06","volume":"45","author":"S Mitka","year":"2007","unstructured":"Mitka S, Anetakis C, Souliou E, Diza E, Kansouzidou A (2007) Evaluation of different PCR assays for early detection of acute and relapsing brucellosis in humans in comparison with conventional methods. J Clin Microbiol 45(4):1211\u20131218. doi: 10.1128\/JCM.00010-06","journal-title":"J Clin Microbiol"},{"issue":"7","key":"1767_CR10","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1128\/JCM.02159-08","volume":"47","author":"MJ Casta\u00f1o","year":"2009","unstructured":"Casta\u00f1o MJ, Solera J (2009) Chronic brucellosis and persistence of Brucella melitensis DNA. J Clin Microbiol 47(7):2084\u20132089. doi: 10.1128\/JCM.02159-08","journal-title":"J Clin Microbiol"},{"issue":"2","key":"1767_CR11","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ab.2005.05.015","volume":"343","author":"D Busso","year":"2005","unstructured":"Busso D, Delagoutte-Busso B, Moras D (2005) Construction of a set Gateway-based destination vectors for high-throughput cloning and expression screening in Escherichia coli. Anal Biochem 343(2):313\u2013321","journal-title":"Anal Biochem"},{"issue":"6","key":"1767_CR12","doi-asserted-by":"crossref","first-page":"3734","DOI":"10.1128\/IAI.73.6.3734-3739.2005","volume":"73","author":"B Li","year":"2005","unstructured":"Li B, Jiang L, Song Q, Yang J, Chen Z, Guo Z, Zhou D, Du Z, Song Y, Wang J, Wang H, Yu S, Wang J, Yang R (2005) Protein microarray for profiling antibody responses to Yersinia pestis live vaccine. Infect Immun 73(6):3734\u20133739. doi: 10.1128\/IAI.73.6.3734-3739.2005","journal-title":"Infect Immun"},{"issue":"12","key":"1767_CR13","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1038\/nbt910","volume":"21","author":"GA Michaud","year":"2003","unstructured":"Michaud GA, Salcius M, Zhou F, Bangham R, Bonin J, Guo H, Snyder M, Predki PF, Schweitzer BI (2003) Analyzing antibody specificity with whole proteome microarrays. Nat Biotechnol 21(12):1509\u20131512","journal-title":"Nat Biotechnol"},{"issue":"13","key":"1767_CR14","doi-asserted-by":"crossref","first-page":"3767","DOI":"10.1002\/pmic.200500730","volume":"6","author":"JP Connolly","year":"2006","unstructured":"Connolly JP, Comerci D, Alefantis TG, Walz A, Quan M, Chafin R, Grewal P, Mujer CV, Ugalde RA, DelVecchio VG (2006) Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development. Proteomics 6(13):3767\u20133780. doi: 10.1002\/pmic.200500730","journal-title":"Proteomics"},{"issue":"10","key":"1767_CR15","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/0264-410X(96)00018-7","volume":"14","author":"SC Oliveira","year":"1996","unstructured":"Oliveira SC, Splitter GA (1996) Immunization of mice with recombinant L7\/L12 ribosomal protein confers protection against Brucella abortus infection. Vaccine 14(10):959\u2013962","journal-title":"Vaccine"},{"issue":"12","key":"1767_CR16","doi-asserted-by":"crossref","first-page":"7053","DOI":"10.1128\/IAI.71.12.7053-7060.2003","volume":"71","author":"P Lestrate","year":"2003","unstructured":"Lestrate P, Dricot A, Delrue RM, Lambert C, Martinelli V, De Bolle X, Letesson JJ, Tibor A (2003) Attenuated signature-tagged mutagenesis mutants of Brucella melitensis identified during the acute phase of infection in mice. Infect Immun 71(12):7053\u20137060","journal-title":"Infect Immun"},{"issue":"3\u20134","key":"1767_CR17","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.vetmic.2011.03.031","volume":"151","author":"Y Wang","year":"2011","unstructured":"Wang Y, Bai Y, Qu Q, Xu J, Chen Y, Zhong Z, Qiu Y, Wang T, Du X, Wang Z, Yu S, Fu S, Yuan J, Zhen Q, Yu Y, Chen Z, Huang L (2011) The 16M\u0394vjbR as an ideal live attenuated vaccine candidate for differentiation between Brucella vaccination and infection. Vet Microbiol 151(3\u20134):354\u2013362. doi: 10.1016\/j.vetmic.2011.03.031","journal-title":"Vet Microbiol"},{"issue":"2","key":"1767_CR18","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1574-695X.2010.00758.x","volume":"61","author":"Y Yang","year":"2011","unstructured":"Yang Y, Yin J, Guo D, Lang X, Wang X (2011) Immunization of mice with recombinant S-adenosyl-L-homocysteine hydrolase protein confers protection against Brucella melitensis infection. FEMS Immunol Med Microbiol 61(2):159\u2013167. doi: 10.1111\/j.1574-695X.2010.00758.x","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"1\u20132","key":"1767_CR19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.vetmic.2003.12.010","volume":"100","author":"K Nielsen","year":"2004","unstructured":"Nielsen K, Smith P, Widdison J, Gall D, Kelly L, Kelly W, Nicoletti P (2004) Serological relationship between cattle exposed to Brucella abortus, Yersinia enterocolitica O:9 and Escherichia coli O157:H7. Vet Microbiol 100(1\u20132):25\u201330. doi: 10.1016\/j.vetmic.2003.12.010","journal-title":"Vet Microbiol"},{"issue":"1","key":"1767_CR20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1017\/S0950268800049529","volume":"108","author":"H Chart","year":"1992","unstructured":"Chart H, Okubadejo OA, Rowe B (1992) The serological relationship between Escherichia coli O157 and Yersinia enterocolitica O9 using sera from patients with brucellosis. Epidemiol Infect 108(1):77\u201385","journal-title":"Epidemiol Infect"},{"issue":"4","key":"1767_CR21","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1128\/CDLI.10.4.647-651.2003","volume":"10","author":"P Seco-Mediavilla","year":"2003","unstructured":"Seco-Mediavilla P, Verger JM, Grayon M, Cloeckaert A, Mar\u00edn CM, Zygmunt MS, Fern\u00e1ndez-Lago L, Vizca\u00edno N (2003) Epitope mapping of the Brucella melitensis BP26 immunogenic protein: usefulness for diagnosis of sheep brucellosis. Clin Diagn Lab Immunol 10(4):647\u2013651","journal-title":"Clin Diagn Lab Immunol"},{"issue":"1","key":"1767_CR22","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1128\/JCM.34.1.165-169.1996","volume":"34","author":"OL Rossetti","year":"1996","unstructured":"Rossetti OL, Arese AI, Boschiroli ML, Cravero SL (1996) Cloning of Brucella abortus gene and characterization of expressed 26-kilodalton periplasmic protein: potential use for diagnosis. J Clin Microbiol 34(1):165\u2013169","journal-title":"J Clin Microbiol"},{"issue":"2\u20133","key":"1767_CR23","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1574-6968.1996.tb08327.x","volume":"140","author":"A Cloeckaert","year":"1996","unstructured":"Cloeckaert A, Debbarh HS, Vizca\u00edno N, Saman E, Dubray G, Zygmunt MS (1996) Cloning, nucleotide sequence, and expression of the Brucella melitensis bp26 gene coding for a protein immunogenic in infected sheep. FEMS Microbiol Lett 140(2\u20133):139\u2013144","journal-title":"FEMS Microbiol Lett"},{"issue":"5","key":"1767_CR24","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1128\/CDLI.4.5.556-564.1997","volume":"4","author":"JJ Letesson","year":"1997","unstructured":"Letesson JJ, Tibor A, van Eynde G, Wansard V, Weynants V, Denoel P, Saman E (1997) Humoral immune responses of Brucella-infected cattle, sheep, and goats to eight purified recombinant Brucella proteins in an indirect enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 4(5):556\u2013564","journal-title":"Clin Diagn Lab Immunol"},{"issue":"3","key":"1767_CR25","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.mcp.2009.12.002","volume":"24","author":"P Chaudhuri","year":"2010","unstructured":"Chaudhuri P, Prasad R, Kumar V, Basavarajappa AG (2010) Recombinant OMP28 antigen-based indirect ELISA for serodiagnosis of bovine brucellosis. Mol Cell Probes 24(3):142\u2013145. doi: 10.1016\/j.mcp.2009.12.002","journal-title":"Mol Cell Probes"},{"issue":"1\u20132","key":"1767_CR26","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jim.2005.11.003","volume":"309","author":"S Al Dahouk","year":"2006","unstructured":"Al Dahouk S, N\u00f6ckler K, Scholz HC, Tomaso H, Bogumil R, Neubauer H (2006) Immunoproteomic characterization of Brucella abortus 1119-3 preparations used for the serodiagnosis of Brucella infections. J Immunol Methods 309(1\u20132):34\u201347. doi: 10.1016\/j.jim.2005.11.003","journal-title":"J Immunol Methods"},{"issue":"11","key":"1767_CR27","doi-asserted-by":"crossref","first-page":"7297","DOI":"10.1128\/IAI.73.11.7297-7303.2005","volume":"73","author":"X Yang","year":"2005","unstructured":"Yang X, Hudson M, Walters N, Bargatze RF, Pascual DW (2005) Selection of protective epitopes for Brucella melitensis by DNA vaccination. Infect Immun 73(11):7297\u20137303. doi: 10.1128\/IAI.73.11.7297-7303.2005","journal-title":"Infect Immun"},{"issue":"2","key":"1767_CR28","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jinf.2007.10.010","volume":"56","author":"R Sharma","year":"2008","unstructured":"Sharma R, Chisnall C, Cooke RP (2008) Evaluation of in-house and commercial immunoassays for the sero-diagnosis of brucellosis in a non-endemic low prevalence population. J Infect 56(2):108\u2013113. doi: 10.1016\/j.jinf.2007.10.010","journal-title":"J Infect"},{"issue":"37\u201338","key":"1767_CR29","doi-asserted-by":"crossref","first-page":"6721","DOI":"10.1016\/j.vaccine.2007.07.002","volume":"25","author":"MV Delpino","year":"2007","unstructured":"Delpino MV, Estein SM, Fossati CA, Baldi PC, Cassataro J (2007) Vaccination with Brucella recombinant DnaK and SurA proteins induces protection against Brucella abortus infection in BALB\/c mice. Vaccine 25(37\u201338):6721\u20136729. doi: 10.1016\/j.vaccine.2007.07.002","journal-title":"Vaccine"},{"issue":"5","key":"1767_CR30","doi-asserted-by":"crossref","first-page":"e673","DOI":"10.1371\/journal.pntd.0000673","volume":"4","author":"L Liang","year":"2010","unstructured":"Liang L, Leng D, Burk C, Nakajima-Sasaki R, Kayala MA, Atluri VL, Pablo J, Unal B, Ficht TA, Gotuzzo E, Saito M, Morrow WJ, Liang X, Baldi P, Gilman RH, Vinetz JM, Tsolis RM, Felgner PL (2010) Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens. PLoS Negl Trop Dis 4(5):e673. doi: 10.1371\/journal.pntd.0000673","journal-title":"PLoS Negl Trop Dis"},{"issue":"32","key":"1767_CR31","doi-asserted-by":"crossref","first-page":"13499","DOI":"10.1073\/pnas.0812080106","volume":"106","author":"PL Felgner","year":"2009","unstructured":"Felgner PL, Kayala MA, Vigil A, Burk C, Nakajima-Sasaki R, Pablo J, Molina DM, Hirst S, Chew JS, Wang D, Tan G, Duffield M, Yang R, Neel J, Chantratita N, Bancroft G, Lertmemongkolchai G, Davies DH, Baldi P, Peacock S, Titball RW (2009) A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens. Proc Natl Acad Sci U S A 106(32):13499\u201313504. doi: 10.1073\/pnas.0812080106","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"1767_CR32","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1600-065X.2010.00982.x","volume":"240","author":"A Martirosyan","year":"2011","unstructured":"Martirosyan A, Moreno E, Gorvel JP (2011) An evolutionary strategy for a stealthy intracellular Brucella pathogen. Immunol Rev 240(1):211\u2013234. doi: 10.1111\/j.1600-065X.2010.00982.x","journal-title":"Immunol Rev"},{"issue":"1","key":"1767_CR33","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1128\/IAI.68.1.257-263.2000","volume":"68","author":"MO Eze","year":"2000","unstructured":"Eze MO, Yuan L, Crawford RM, Paranavitana CM, Hadfield TL, Bhattacharjee AK, Warren RL, Hoover DL (2000) Effects of opsonization and gamma interferon on growth of Brucella melitensis 16M in mouse peritoneal macrophages in vitro. Infect Immun 68(1):257\u2013263","journal-title":"Infect Immun"},{"issue":"11","key":"1767_CR34","doi-asserted-by":"crossref","first-page":"4899","DOI":"10.1128\/IAI.61.11.4899-4901.1993","volume":"61","author":"Y Zhan","year":"1993","unstructured":"Zhan Y, Cheers C (1993) Endogenous gamma interferon mediates resistance to Brucella abortus infection. Infect Immun 61(11):4899\u20134901","journal-title":"Infect Immun"},{"issue":"2","key":"1767_CR35","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0165-2427(89)90069-X","volume":"21","author":"Z Bercovich","year":"1989","unstructured":"Bercovich Z, Lagendijk W, Bokhout BA (1989) Evaluation of a delayed-type hypersensitivity test for the diagnosis of Brucella abortus infection in cattle. Vet Immunol Immunopathol 21(2):213\u2013218","journal-title":"Vet Immunol Immunopathol"},{"issue":"2\u20133","key":"1767_CR36","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0378-1135(90)90111-8","volume":"22","author":"Z Bercovich","year":"1990","unstructured":"Bercovich Z, ter Laak EA (1990) An evaluation of the delayed-type hypersensitivity test for diagnosing brucellosis in individual cattle: a field study. Vet Microbiol 22(2\u20133):241\u2013248","journal-title":"Vet Microbiol"},{"issue":"3","key":"1767_CR37","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1128\/JCM.33.3.706-712.1995","volume":"33","author":"V Weynants","year":"1995","unstructured":"Weynants V, Godfroid J, Limbourg B, Saegerman C, Letesson JJ (1995) Specific bovine brucellosis diagnosis based on in vitro antigen-specific gamma interferon production. J Clin Microbiol 33(3):706\u2013712","journal-title":"J Clin Microbiol"},{"issue":"2","key":"1767_CR38","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.micinf.2010.10.015","volume":"13","author":"P Skendros","year":"2011","unstructured":"Skendros P, Pappas G, Boura P (2011) Cell-mediated immunity in human brucellosis. Microbes Infect 13(2):134\u2013142. doi: 10.1016\/j.micinf.2010.10.015","journal-title":"Microbes Infect"},{"issue":"18","key":"1767_CR39","doi-asserted-by":"crossref","first-page":"3692","DOI":"10.1016\/j.vaccine.2007.01.066","volume":"25","author":"AI Mallick","year":"2007","unstructured":"Mallick AI, Singha H, Chaudhuri P, Nadeem A, Khan SA, Dar KA, Owais M (2007) Liposomised recombinant ribosomal L7\/L12 protein protects BALB\/c mice against Brucella abortus 544 infection. Vaccine 25(18):3692\u20133704. doi: 10.1016\/j.vaccine.2007.01.066","journal-title":"Vaccine"},{"issue":"2","key":"1767_CR40","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S1286-4579(02)00075-8","volume":"5","author":"SM Estein","year":"2003","unstructured":"Estein SM, Cassataro J, Vizca\u00edno N, Zygmunt MS, Cloeckaert A, Bowden RA (2003) The recombinant Omp31 from Brucella melitensis alone or associated with rough lipopolysaccharide induces protection against Brucella ovis infection in BALB\/c mice. Microbes Infect 5(2):85\u201393","journal-title":"Microbes Infect"},{"issue":"5","key":"1767_CR41","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1128\/IAI.74.5.2734-2741.2006","volume":"74","author":"D Luo","year":"2006","unstructured":"Luo D, Ni B, Li P, Shi W, Zhang S, Han Y, Mao L, He Y, Wu Y, Wang X (2006) Protective immunity elicited by a divalent DNA vaccine encoding both the L7\/L12 and Omp16 genes of Brucella abortus in BALB\/c mice. Infect Immun 74(5):2734\u20132741. doi: 10.1128\/IAI.74.5.2734-2741.2006","journal-title":"Infect Immun"},{"issue":"1","key":"1767_CR42","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1128\/IAI.01151-08","volume":"77","author":"KA Pasquevich","year":"2009","unstructured":"Pasquevich KA, Estein SM, Garc\u00eda Samartino C, Zwerdling A, Coria LM, Barrionuevo P, Fossati CA, Giambartolomei GH, Cassataro J (2009) Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+ and CD8+ T cells as well as systemic and oral protection against Brucella abortus infection. Infect Immun 77(1):436\u2013445. doi: 10.1128\/IAI.01151-08","journal-title":"Infect Immun"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-012-1767-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-012-1767-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-012-1767-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T03:34:03Z","timestamp":1594870443000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-012-1767-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,15]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["1767"],"URL":"https:\/\/doi.org\/10.1007\/s10096-012-1767-7","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,15]]}}}