{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:27:30Z","timestamp":1787164050696,"version":"build-2736575974"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1007\/s10096-013-2022-6","type":"journal-article","created":{"date-parts":[[2013,12,3]],"date-time":"2013-12-03T06:39:07Z","timestamp":1386052747000},"page":"837-843","source":"Crossref","is-referenced-by-count":48,"title":["Fitness cost associated with resistance to fluoroquinolones is diverse across clones of Klebsiella pneumoniae and may select for CTX-M-15 type extended-spectrum \u03b2-lactamase"],"prefix":"10.1007","volume":"33","author":[{"given":"\u00c1.","family":"T\u00f3th","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Kocsis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Damjanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Krist\u00f3f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"J\u00e1nv\u00e1ri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"P\u00e1szti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Csercsik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Topf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Szab\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Hamar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"F\u00fczi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,4]]},"reference":[{"key":"2022_CR1","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S1473-3099(09)70054-4","volume":"9","author":"P Nordmann","year":"2009","unstructured":"Nordmann P, Cuzon G, Naas T (2009) The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 9:228\u2013236","journal-title":"Lancet Infect Dis"},{"key":"2022_CR2","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/j.meegid.2011.06.001","volume":"11","author":"Y Chong","year":"2011","unstructured":"Chong Y, Ito Y, Kamimura T (2011) Genetic evolution and clinical impact in extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella pneumoniae. Infect Genet Evol 11:1499\u20131504","journal-title":"Infect Genet Evol"},{"key":"2022_CR3","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3904\/kjim.2012.27.2.128","volume":"27","author":"DM Livermore","year":"2012","unstructured":"Livermore DM (2012) Current epidemiology and growing resistance of gram-negative pathogens. Korean J Intern Med 27:128\u2013142","journal-title":"Korean J Intern Med"},{"key":"2022_CR4","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1473-3099(10)70143-2","volume":"10","author":"KK Kumarasamy","year":"2010","unstructured":"Kumarasamy KK, Toleman MA, Walsh TR, Bagaria J, Butt F, Balakrishnan R, Chaudhary U, Doumith M, Giske CG, Irfan S, Krishnan P, Kumar AV, Maharjan S, Mushtaq S, Noorie T, Paterson DL, Pearson A, Perry C, Pike R, Rao B, Ray U, Sarma JB, Sharma M, Sheridan E, Thirunarayan MA, Turton J, Upadhyay S, Warner M, Welfare W, Livermore DM, Woodford N (2010) Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 10:597\u2013602","journal-title":"Lancet Infect Dis"},{"key":"2022_CR5","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1128\/CMR.05035-11","volume":"25","author":"LS Tzouvelekis","year":"2012","unstructured":"Tzouvelekis LS, Markogiannakis A, Psichogiou M, Tassios PT, Daikos GL (2012) Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions. Clin Microbiol Rev 25:682\u2013707","journal-title":"Clin Microbiol Rev"},{"key":"2022_CR6","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S1473-3099(13)70190-7","volume":"13","author":"LS Munoz-Price","year":"2013","unstructured":"Munoz-Price LS, Poirel L, Bonomo RA, Schwaber MJ, Daikos GL, Cormican M, Cornaglia G, Garau J, Gniadkowski M, Hayden MK, Kumarasamy K, Livermore DM, Maya JJ, Nordmann P, Patel JB, Paterson DL, Pitout J, Villegas MV, Wang H, Woodford N, Quinn JP (2013) Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect Dis 13:785\u2013796","journal-title":"Lancet Infect Dis"},{"key":"2022_CR7","doi-asserted-by":"crossref","first-page":"R174","DOI":"10.1186\/cc12853","volume":"17","author":"M Rocco","year":"2013","unstructured":"Rocco M, Montini L, Alessandri E, Venditti M, Laderchi A, De Gennaro P, Raponi G, Vitale M, Pietropaoli P, Antonelli M (2013) Risk factors for acute kidney injury in critically ill patients receiving high intravenous doses of colistin methanesulfonate and\/or other nephrotoxic antibiotics: a retrospective cohort study. Crit Care 17:R174","journal-title":"Crit Care"},{"key":"2022_CR8","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1186\/1471-2334-13-380","volume":"13","author":"L Sorl\u00ed","year":"2013","unstructured":"Sorl\u00ed L, Luque S, Grau S, Berenguer N, Segura C, Montero MM, Alvarez-Lerma F, Knobel H, Benito N, Horcajada JP (2013) Trough colistin plasma level is an independent risk factor for nephrotoxicity: a prospective observational cohort study. BMC Infect Dis 13:380","journal-title":"BMC Infect Dis"},{"key":"2022_CR9","doi-asserted-by":"crossref","first-page":"e268","DOI":"10.1097\/PCC.0b013e31828a740f","volume":"14","author":"K Kapoor","year":"2013","unstructured":"Kapoor K, Jajoo M, Dublish S, Dabas V, Gupta S, Manchanda V (2013) Intravenous colistin for multidrug-resistant gram-negative infections in critically ill pediatric patients. Pediatr Crit Care Med 14:e268\u2013e272","journal-title":"Pediatr Crit Care Med"},{"key":"2022_CR10","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.mib.2006.08.011","volume":"9","author":"R Cant\u00f3n","year":"2006","unstructured":"Cant\u00f3n R, Coque TM (2006) The CTX-M \u03b2-lactamase pandemic. Curr Opin Microbiol 9:466\u2013475","journal-title":"Curr Opin Microbiol"},{"key":"2022_CR11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1093\/jac\/dkl483","volume":"59","author":"DM Livermore","year":"2007","unstructured":"Livermore DM, Canton R, Gniadkowski M, Nordmann P, Rossolini GM, Arlet G, Ayala J, Coque TM, Kern-Zdanowicz I, Luzzaro F, Poirel L, Woodford N (2007) CTX-M: changing the face of ESBLs in Europe. J Antimicrob Chemother 59:165\u2013174","journal-title":"J Antimicrob Chemother"},{"key":"2022_CR12","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1093\/jac\/dkn287","volume":"62","author":"I Damjanova","year":"2008","unstructured":"Damjanova I, T\u00f3th A, P\u00e1szti J, Hajbel-V\u00e9kony G, Jakab M, Berta J, Milch H, F\u00fczi M (2008) Expansion and countrywide dissemination of ST11, ST15 and ST147 ciprofloxacin-resistant CTX-M-15-type \u03b2-lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005\u2014the new \u2018MRSAs\u2019? J Antimicrob Chemother 62:978\u2013985","journal-title":"J Antimicrob Chemother"},{"key":"2022_CR13","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1099\/jmm.0.018119-0","volume":"59","author":"KS Ko","year":"2010","unstructured":"Ko KS, Lee JY, Baek JY, Suh JY, Lee MY, Choi JY, Yeom JS, Kim YS, Jung SI, Shin SY, Heo ST, Kwon KT, Son JS, Kim SW, Chang HH, Ki HK, Chung DR, Peck KR, Song JH (2010) Predominance of an ST11 extended-spectrum \u03b2-lactamase-producing Klebsiella pneumoniae clone causing bacteraemia and urinary tract infections in Korea. J Med Microbiol 59:822\u2013828","journal-title":"J Med Microbiol"},{"key":"2022_CR14","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s10096-011-1153-x","volume":"30","author":"JB Nielsen","year":"2011","unstructured":"Nielsen JB, Skov MN, J\u00f8rgensen RL, Heltberg O, Hansen DS, Sch\u00f8nning K (2011) Identification of CTX-M-15-, SHV-28-producing Klebsiella pneumoniae ST15 as an epidemic clone in the Copenhagen area using a semi-automated Rep-PCR typing assay. Eur J Clin Microbiol Infect Dis 30:773\u2013778","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2022_CR15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jinf.2011.05.003","volume":"63","author":"J Shin","year":"2011","unstructured":"Shin J, Kim DH, Ko KS (2011) Comparison of CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae isolates from patients with bacteremia. J Infect 63:39\u201347","journal-title":"J Infect"},{"key":"2022_CR16","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ijantimicag.2011.03.020","volume":"38","author":"MY Lee","year":"2011","unstructured":"Lee MY, Ko KS, Kang CI, Chung DR, Peck KR, Song JH (2011) High prevalence of CTX-M-15-producing Klebsiella pneumoniae isolates in Asian countries: diverse clones and clonal dissemination. Int J Antimicrob Agents 38:160\u2013163","journal-title":"Int J Antimicrob Agents"},{"key":"2022_CR17","doi-asserted-by":"crossref","first-page":"6003","DOI":"10.1128\/AAC.00745-12","volume":"56","author":"S Sennati","year":"2012","unstructured":"Sennati S, Santella G, Di Conza J, Pallecchi L, Pino M, Ghiglione B, Rossolini GM, Radice M, Gutkind G (2012) Changing epidemiology of extended-spectrum \u03b2-lactamases in Argentina: emergence of CTX-M-15. Antimicrob Agents Chemother 56:6003\u20136005","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR18","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1128\/AAC.02571-12","volume":"57","author":"A Baraniak","year":"2013","unstructured":"Baraniak A, Izdebski R, Fiett J, Sadowy E, Adler A, Kazma M, Salomon J, Lawrence C, Rossini A, Salvia A, Vidal Samso J, Fierro J, Paul M, Lerman Y, Malhotra-Kumar S, Lammens C, Goossens H, Hryniewicz W, Brun-Buisson C, Carmeli Y, Gniadkowski M; MOSAR WP2 and WP5 Study Groups (2013) Comparative population analysis of Klebsiella pneumoniae strains with extended-spectrum \u03b2-lactamases colonizing patients in rehabilitation centers in four countries. Antimicrob Agents Chemother 57:1992\u20131997","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR19","doi-asserted-by":"crossref","first-page":"3579","DOI":"10.1128\/AAC.01783-10","volume":"55","author":"LN Andrade","year":"2011","unstructured":"Andrade LN, Curiao T, Ferreira JC, Longo JM, Cl\u00edmaco EC, Martinez R, Bellissimo-Rodrigues F, Basile-Filho A, Evaristo MA, Del Peloso PF, Ribeiro VB, Barth AL, Paula MC, Baquero F, Cant\u00f3n R, Darini AL, Coque TM (2011) Dissemination of bla KPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL\/M) among Enterobacteriaceae species in Brazil. Antimicrob Agents Chemother 55:3579\u20133583","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR20","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1128\/AAC.05942-11","volume":"56","author":"M Castanheira","year":"2012","unstructured":"Castanheira M, Costello AJ, Deshpande LM, Jones RN (2012) Expansion of clonal complex 258 KPC-2-producing Klebsiella pneumoniae in Latin American hospitals: report of the SENTRY Antimicrobial Surveillance Program. Antimicrob Agents Chemother 56:1668\u20131669","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR21","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1093\/jac\/dkq133","volume":"65","author":"K Krist\u00f3f","year":"2010","unstructured":"Krist\u00f3f K, T\u00f3th A, Damjanova I, J\u00e1nv\u00e1ri L, Konkoly-Thege M, Kocsis B, Koncan R, Cornaglia G, Szego E, Nagy K, Szab\u00f3 D (2010) Identification of a bla VIM-4 gene in the internationally successful Klebsiella pneumoniae ST11 clone and in a Klebsiella oxytoca strain in Hungary. J Antimicrob Chemother 65:1303\u20131305","journal-title":"J Antimicrob Chemother"},{"key":"2022_CR22","author":"CM Hasan","year":"2013","unstructured":"Hasan CM, Turlej-Rogacka A, Vatopoulos AC, Giakkoupi P, Ma\u00e2tallah M, Giske CG (2013) Dissemination of bla VIM in Greece at the peak of the epidemic of 2005\u20132006: clonal expansion of Klebsiella pneumoniae clonal complex 147. Clin Microbiol Infect. doi: 10.1111\/1469-0691.12187","journal-title":"Clin Microbiol Infect"},{"key":"2022_CR23","author":"S Melegh","year":"2013","unstructured":"Melegh S, Kov\u00e1cs K, G\u00e1m T, Nyul A, Patk\u00f3 B, T\u00f3th A, Damjanova I, Mesty\u00e1n G (2013) Emergence of VIM-4 metallo-\u03b2-lactamase-producing Klebsiella pneumoniae ST15 clone in the Clinical Centre University of P\u00e9cs, Hungary. Clin Microbiol Infect. doi: 10.1111\/1469-0691.12293","journal-title":"Clin Microbiol Infect"},{"issue":"Suppl 1","key":"2022_CR24","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1469-0691.2007.01867.x","volume":"14","author":"GM Rossolini","year":"2008","unstructured":"Rossolini GM, D\u2019Andrea MM, Mugnaioli C (2008) The spread of CTX-M-type extended-spectrum \u03b2-lactamases. Clin Microbiol Infect 14(Suppl 1):33\u201341","journal-title":"Clin Microbiol Infect"},{"key":"2022_CR25","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s10096-006-0120-4","volume":"25","author":"I Damjanova","year":"2006","unstructured":"Damjanova I, T\u00f3th A, P\u00e1szti J, Bauernfeind A, F\u00fczi M (2006) Nationwide spread of clonally related CTX-M-15-producing multidrug-resistant Klebsiella pneumoniae strains in Hungary. Eur J Clin Microbiol Infect Dis 25:275\u2013278","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2022_CR26","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s10096-005-1315-9","volume":"24","author":"A T\u00f3th","year":"2005","unstructured":"T\u00f3th A, Gacs M, M\u00e1rialigeti K, Cech G, F\u00fczi M (2005) Occurrence and regional distribution of SHV-type extended-spectrum \u03b2-lactamases in Hungary. Eur J Clin Microbiol Infect Dis 24:284\u2013287","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2022_CR27","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.ijantimicag.2006.12.020","volume":"29","author":"I Damjanova","year":"2007","unstructured":"Damjanova I, T\u00f3th A, P\u00e1szti J, Jakab M, Milch H, Bauernfeind A, F\u00fczi M (2007) Epidemiology of SHV-type \u03b2-lactamase-producing Klebsiella spp. from outbreaks in five geographically distant Hungarian neonatal intensive care units: widespread dissemination of epidemic R-plasmids. Int J Antimicrob Agents 29:665\u2013671","journal-title":"Int J Antimicrob Agents"},{"key":"2022_CR28","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1556\/AMicr.57.2010.1.4","volume":"57","author":"E Szil\u00e1gyi","year":"2010","unstructured":"Szil\u00e1gyi E, F\u00fczi M, Damjanova I, B\u00f6r\u00f6cz K, Szonyi K, T\u00f3th A, Nagy K (2010) Investigation of extended-spectrum \u03b2-lactamase-producing Klebsiella pneumoniae outbreaks in Hungary between 2005 and 2008. Acta Microbiol Immunol Hung 57:43\u201353","journal-title":"Acta Microbiol Immunol Hung"},{"key":"2022_CR29","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1007\/s10096-011-1536-z","volume":"31","author":"A Horv\u00e1th","year":"2012","unstructured":"Horv\u00e1th A, Dobay O, Kardos S, Ghid\u00e1n \u00c1, T\u00f3th \u00c1, P\u00e1szti J, Ungv\u00e1ri E, Horv\u00e1th P, Nagy K, Zissman S, F\u00fczi M (2012) Varying fitness cost associated with resistance to fluoroquinolones governs clonal dynamic of methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis 31:2029\u20132036","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2022_CR30","doi-asserted-by":"crossref","DOI":"10.1128\/9781555816728","volume-title":"Manual of clinical microbiology","author":"J Versalovic","year":"2011","unstructured":"Versalovic J (2011) Manual of clinical microbiology, 10th edn. ASM Press, Washington DC","edition":"10"},{"key":"2022_CR31","unstructured":"European Committee on Antimicrobial Susceptibility Testing (EUCAST) (2012) Antimicrobial susceptibility testing. Home page at: http:\/\/www.eucast.org"},{"key":"2022_CR32","doi-asserted-by":"crossref","first-page":"4178","DOI":"10.1128\/JCM.43.8.4178-4182.2005","volume":"43","author":"L Diancourt","year":"2005","unstructured":"Diancourt L, Passet V, Verhoef J, Grimont PA, Brisse S (2005) Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol 43:4178\u20134182","journal-title":"J Clin Microbiol"},{"key":"2022_CR33","volume-title":"Standardized molecular subtyping of foodborne bacterial pathogens by pulsed-field gel electrophoresis: training manual","author":"Centers for Disease Control and Prevention (CDC)","year":"2000","unstructured":"Centers for Disease Control and Prevention (CDC) (2000) Standardized molecular subtyping of foodborne bacterial pathogens by pulsed-field gel electrophoresis: training manual. CDC, Atlanta, GA"},{"key":"2022_CR34","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ijantimicag.2012.10.004","volume":"41","author":"YS Nam","year":"2013","unstructured":"Nam YS, Cho SY, Yang HY, Park KS, Jang JH, Kim YT, Jeong JW, Suh JT, Lee HJ (2013) Investigation of mutation distribution in DNA gyrase and topoisomerase IV genes in ciprofloxacin-non-susceptible Enterobacteriaceae isolated from blood cultures in a tertiary care university hospital in South Korea, 2005\u20132010. Int J Antimicrob Agents 41:126\u2013129","journal-title":"Int J Antimicrob Agents"},{"key":"2022_CR35","doi-asserted-by":"crossref","first-page":"2872","DOI":"10.1128\/AAC.01647-05","volume":"50","author":"A Robicsek","year":"2006","unstructured":"Robicsek A, Strahilevitz J, Sahm DF, Jacoby GA, Hooper DC (2006) qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States. Antimicrob Agents Chemother 50:2872\u20132874","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR36","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1128\/AAC.50.4.1178-1182.2006","volume":"50","author":"GA Jacoby","year":"2006","unstructured":"Jacoby GA, Walsh KE, Mills DM, Walker VJ, Oh H, Robicsek A, Hooper DC (2006) qnrB, another plasmid-mediated gene for quinolone resistance. Antimicrob Agents Chemother 50:1178\u20131182","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR37","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1128\/AAC.00997-08","volume":"53","author":"LM Cavaco","year":"2009","unstructured":"Cavaco LM, Hasman H, Xia S, Aarestrup FM (2009) qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin. Antimicrob Agents Chemother 53:603\u2013608","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR38","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1128\/AAC.01400-08","volume":"53","author":"M Wang","year":"2009","unstructured":"Wang M, Guo Q, Xu X, Wang X, Ye X, Wu S, Hooper DC, Wang M (2009) New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. Antimicrob Agents Chemother 53:1892\u20131897","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR39","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1128\/AAC.00915-06","volume":"50","author":"CH Park","year":"2006","unstructured":"Park CH, Robicsek A, Jacoby GA, Sahm D, Hooper DC (2006) Prevalence in the United States of aac(6\u2032)-Ib-cr encoding a ciprofloxacin-modifying enzyme. Antimicrob Agents Chemother 50:3953\u20133955","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR40","doi-asserted-by":"crossref","first-page":"3582","DOI":"10.1128\/AAC.01574-08","volume":"53","author":"HB Kim","year":"2009","unstructured":"Kim HB, Wang M, Park CH, Kim EC, Jacoby GA, Hooper DC (2009) oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae. Antimicrob Agents Chemother 53:3582\u20133584","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR41","doi-asserted-by":"crossref","first-page":"3354","DOI":"10.1128\/AAC.00339-07","volume":"51","author":"K Yamane","year":"2007","unstructured":"Yamane K, Wachino J, Suzuki S, Kimura K, Shibata N, Kato H, Shibayama K, Konda T, Arakawa Y (2007) New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrob Agents Chemother 51:3354\u20133360","journal-title":"Antimicrob Agents Chemother"},{"key":"2022_CR42","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/jac\/40.4.543","volume":"40","author":"T Deguchi","year":"1997","unstructured":"Deguchi T, Yasuda M, Nakano M, Ozeki S, Kanematsu E, Nishino Y, Ishihara S, Kawada Y (1997) Detection of mutations in the gyrA and parC genes in quinolone-resistant clinical isolates of Enterobacter cloacae. J Antimicrob Chemother 40:543\u2013549","journal-title":"J Antimicrob Chemother"},{"key":"2022_CR43","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2334-13-8","volume":"13","author":"Y Fu","year":"2013","unstructured":"Fu Y, Zhang W, Wang H, Zhao S, Chen Y, Meng F, Zhang Y, Xu H, Chen X, Zhang F (2013) Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis 13:8","journal-title":"BMC Infect Dis"},{"key":"2022_CR44","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.vetmic.2008.05.009","volume":"132","author":"L Yue","year":"2008","unstructured":"Yue L, Jiang HX, Liao XP, Liu JH, Li SJ, Chen XY, Chen CX, L\u00fc DH, Liu YH (2008) Prevalence of plasmid-mediated quinolone resistance qnr genes in poultry and swine clinical isolates of Escherichia coli. Vet Microbiol 132:414\u2013420","journal-title":"Vet Microbiol"},{"key":"2022_CR45","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ijfoodmicro.2012.02.002","volume":"155","author":"M Nawaz","year":"2012","unstructured":"Nawaz M, Khan SA, Tran Q, Sung K, Khan AA, Adamu I, Steele RS (2012) Isolation and characterization of multidrug-resistant Klebsiella spp. isolated from shrimp imported from Thailand. Int J Food Microbiol 155:179\u2013184","journal-title":"Int J Food Microbiol"},{"key":"2022_CR46","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1089\/mdr.2010.0015","volume":"16","author":"I Vranakis","year":"2010","unstructured":"Vranakis I, Sandalakis V, Chochlakis D, Tselentis Y, Psaroulaki A (2010) DNA gyrase and topoisomerase IV mutations in an in vitro fluoroquinolone-resistant Coxiella burnetii strain. Microb Drug Resist 16:111\u2013117","journal-title":"Microb Drug Resist"},{"key":"2022_CR47","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s10096-010-1147-0","volume":"30","author":"S Aathithan","year":"2011","unstructured":"Aathithan S, French GL (2011) Prevalence and role of efflux pump activity in ciprofloxacin resistance in clinical isolates of Klebsiella pneumoniae. Eur J Clin Microbiol Infect Dis 30:745\u2013752","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2022_CR48","doi-asserted-by":"crossref","first-page":"e1000541","DOI":"10.1371\/journal.ppat.1000541","volume":"5","author":"LL Marcusson","year":"2009","unstructured":"Marcusson LL, Frimodt-M\u00f8ller N, Hughes D (2009) Interplay in the selection of fluoroquinolone resistance and bacterial fitness. PLoS Pathog 5:e1000541","journal-title":"PLoS Pathog"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-013-2022-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-013-2022-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-013-2022-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T12:54:28Z","timestamp":1688820868000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-013-2022-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,4]]},"references-count":48,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["2022"],"URL":"https:\/\/doi.org\/10.1007\/s10096-013-2022-6","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,4]]}}}