{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:53:45Z","timestamp":1787068425165,"version":"build-2736575974"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2015,7,4]],"date-time":"2015-07-04T00:00:00Z","timestamp":1435968000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1007\/s10096-015-2423-9","type":"journal-article","created":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T04:20:02Z","timestamp":1435897202000},"page":"1849-1857","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Impact of round-the-clock CSF Gram stain on empirical therapy for suspected central nervous system infections"],"prefix":"10.1007","volume":"34","author":[{"given":"F.","family":"Tissot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Prod\u2019hom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Manuel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Greub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,7,4]]},"reference":[{"issue":"18","key":"2423_CR1","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1056\/NEJMoa040845","volume":"351","author":"D Beek van de","year":"2004","unstructured":"van de Beek D, de Gans J, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M (2004) Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med 351(18):1849\u20131859","journal-title":"N Engl J Med"},{"issue":"11","key":"2423_CR2","doi-asserted-by":"crossref","first-page":"862","DOI":"10.7326\/0003-4819-129-11_Part_1-199812010-00004","volume":"129","author":"SI Aronin","year":"1998","unstructured":"Aronin SI, Peduzzi P, Quagliarello VJ (1998) Community-acquired bacterial meningitis: risk stratification for adverse clinical outcome and effect of antibiotic timing. Ann Intern Med 129(11):862\u2013869","journal-title":"Ann Intern Med"},{"issue":"1","key":"2423_CR3","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1056\/NEJMra052116","volume":"354","author":"D Beek van de","year":"2006","unstructured":"van de Beek D, de Gans J, Tunkel AR, Wijdicks EF (2006) Community-acquired bacterial meningitis in adults. N Engl J Med 354(1):44\u201353","journal-title":"N Engl J Med"},{"issue":"Pt 5","key":"2423_CR4","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1093\/brain\/awg113","volume":"126","author":"S Kastenbauer","year":"2003","unstructured":"Kastenbauer S, Pfister HW (2003) Pneumococcal meningitis in adults: spectrum of complications and prognostic factors in a series of 87 cases. Brain 126(Pt 5):1015\u20131025","journal-title":"Brain"},{"issue":"11","key":"2423_CR5","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1097\/01.CCM.0000239434.26669.65","volume":"34","author":"M Auburtin","year":"2006","unstructured":"Auburtin M, Wolff M, Charpentier J, Varon E, Le Tulzo Y, Girault C et al (2006) Detrimental role of delayed antibiotic administration and penicillin-nonsusceptible strains in adult intensive care unit patients with pneumococcal meningitis: the PNEUMOREA prospective multicenter study. Crit Care Med 34(11):2758\u20132765","journal-title":"Crit Care Med"},{"issue":"21","key":"2423_CR6","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1056\/NEJMoa1005384","volume":"364","author":"MC Thigpen","year":"2011","unstructured":"Thigpen MC, Whitney CG, Messonnier NE, Zell ER, Lynfield R, Hadler JL et al (2011) Bacterial meningitis in the United States, 1998\u20132007. N Engl J Med 364(21):2016\u20132025","journal-title":"N Engl J Med"},{"issue":"4","key":"2423_CR7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1093\/qjmed\/hci047","volume":"98","author":"N Proulx","year":"2005","unstructured":"Proulx N, Fr\u00e9chette D, Toye B, Chan J, Kravcik S (2005) Delays in the administration of antibiotics are associated with mortality from adult acute bacterial meningitis. QJM 98(4):291\u2013298","journal-title":"QJM"},{"issue":"9","key":"2423_CR8","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1086\/425368","volume":"39","author":"AR Tunkel","year":"2004","unstructured":"Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM et al (2004) Practice guidelines for the management of bacterial meningitis. Clin Infect Dis 39(9):1267\u20131284","journal-title":"Clin Infect Dis"},{"issue":"1","key":"2423_CR9","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1086\/588298","volume":"47","author":"A Conen","year":"2008","unstructured":"Conen A, Walti LN, Merlo A, Fluckiger U, Battegay M, Trampuz A (2008) Characteristics and treatment outcome of cerebrospinal fluid shunt-associated infections in adults: a retrospective analysis over an 11-year period. Clin Infect Dis 47(1):73\u201382","journal-title":"Clin Infect Dis"},{"issue":"1","key":"2423_CR10","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3171\/jns.2006.104.1.101","volume":"104","author":"RP Schade","year":"2006","unstructured":"Schade RP, Schinkel J, Roelandse FW, Geskus RB, Visser LG, van Dijk JM et al (2006) Lack of value of routine analysis of cerebrospinal fluid for prediction and diagnosis of external drainage-related bacterial meningitis. J Neurosurg 104(1):101\u2013108","journal-title":"J Neurosurg"},{"issue":"1","key":"2423_CR11","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1086\/520184","volume":"29","author":"SL Leib","year":"1999","unstructured":"Leib SL, Boscacci R, Gratzl O, Zimmerli W (1999) Predictive value of cerebrospinal fluid (CSF) lactate level versus CSF\/blood glucose ratio for the diagnosis of bacterial meningitis following neurosurgery. Clin Infect Dis 29(1):69\u201374","journal-title":"Clin Infect Dis"},{"issue":"2","key":"2423_CR12","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1056\/NEJMra0804573","volume":"362","author":"D Beek van de","year":"2010","unstructured":"van de Beek D, Drake JM, Tunkel AR (2010) Nosocomial bacterial meningitis. N Engl J Med 362(2):146\u2013154","journal-title":"N Engl J Med"},{"issue":"3 Pt 1","key":"2423_CR13","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1542\/peds.102.3.538","volume":"102","author":"SL Kaplan","year":"1998","unstructured":"Kaplan SL, Mason EO Jr, Barson WJ, Wald ER, Arditi M, Tan TQ et al (1998) Three-year multicenter surveillance of systemic pneumococcal infections in children. Pediatrics 102(3 Pt 1):538\u2013545","journal-title":"Pediatrics"},{"issue":"4","key":"2423_CR14","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1001\/archinte.1997.00440250077009","volume":"157","author":"B Sigurdard\u00f3ttir","year":"1997","unstructured":"Sigurdard\u00f3ttir B, Bj\u00f6rnsson OM, J\u00f3nsd\u00f3ttir KE, Erlendsd\u00f3ttir H, Gudmundsson S (1997) Acute bacterial meningitis in adults. A 20-year overview. Arch Intern Med 157(4):425\u2013430","journal-title":"Arch Intern Med"},{"issue":"9854","key":"2423_CR15","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1016\/S0140-6736(12)61185-4","volume":"380","author":"MC Brouwer","year":"2012","unstructured":"Brouwer MC, Thwaites GE, Tunkel AR, van de Beek D (2012) Dilemmas in the diagnosis of acute community-acquired bacterial meningitis. Lancet 380(9854):1684\u20131692","journal-title":"Lancet"},{"issue":"2","key":"2423_CR16","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1128\/JCM.19.2.187-190.1984","volume":"19","author":"LJ Scolea La Jr","year":"1984","unstructured":"La Scolea LJ Jr, Dryja D (1984) Quantitation of bacteria in cerebrospinal fluid and blood of children with meningitis and its diagnostic significance. J Clin Microbiol 19(2):187\u2013190","journal-title":"J Clin Microbiol"},{"issue":"8","key":"2423_CR17","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1128\/JCM.02237-07","volume":"46","author":"YD Wu","year":"2008","unstructured":"Wu YD, Chen LH, Wu XJ, Shang SQ, Lou JT, Du LZ et al (2008) Gram stain-specific-probe-based real-time PCR for diagnosis and discrimination of bacterial neonatal sepsis. J Clin Microbiol 46(8):2613\u20132619","journal-title":"J Clin Microbiol"},{"issue":"6","key":"2423_CR18","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3109\/00365548609021658","volume":"18","author":"J Mancebo","year":"1986","unstructured":"Mancebo J, Domingo P, Blanch L, Coll P, Net A, Nolla J (1986) Post-neurosurgical and spontaneous gram-negative bacillary meningitis in adults. Scand J Infect Dis 18(6):533\u2013538","journal-title":"Scand J Infect Dis"},{"issue":"1","key":"2423_CR19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0022-3476(05)83480-8","volume":"122","author":"M Unhanand","year":"1993","unstructured":"Unhanand M, Mustafa MM, McCracken GH Jr, Nelson JD (1993) Gram-negative enteric bacillary meningitis: a twenty-one-year experience. J Pediatr 122(1):15\u201321","journal-title":"J Pediatr"},{"issue":"11","key":"2423_CR20","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1086\/645760","volume":"9","author":"RL Penn","year":"1988","unstructured":"Penn RL, Normand R, Klotz SA (1988) Factitious meningitis: a recurring problem. Infect Control Hosp Epidemiol 9(11):501\u2013503","journal-title":"Infect Control Hosp Epidemiol"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-015-2423-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-015-2423-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-015-2423-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T09:44:43Z","timestamp":1599212683000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-015-2423-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,4]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["2423"],"URL":"https:\/\/doi.org\/10.1007\/s10096-015-2423-9","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,4]]}}}