{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:09:11Z","timestamp":1762542551889},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2016,5,28]],"date-time":"2016-05-28T00:00:00Z","timestamp":1464393600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010372","name":"Rotterdamse Stichting Blindenbelangen","doi-asserted-by":"crossref","award":["HIVSA_RSB01"],"award-info":[{"award-number":["HIVSA_RSB01"]}],"id":[{"id":"10.13039\/501100010372","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Rotterdam Global Health Initiative","award":["SMG15"],"award-info":[{"award-number":["SMG15"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1007\/s10096-016-2677-x","type":"journal-article","created":{"date-parts":[[2016,5,28]],"date-time":"2016-05-28T14:42:57Z","timestamp":1464446577000},"page":"1403-1409","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical and corneal microbial profile of infectious keratitis in a high HIV prevalence setting in rural South Africa"],"prefix":"10.1007","volume":"35","author":[{"given":"E.","family":"Schaftenaar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. P. H.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. S.","family":"Baarsma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Meenken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. S.","family":"Khosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Getu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. A.","family":"McIntyre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. D. M. E.","family":"Osterhaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. M. G. M.","family":"Verjans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,5,28]]},"reference":[{"key":"2677_CR1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1097\/IIO.0b013e318074e0b3","volume":"47","author":"MP Upadhyay","year":"2007","unstructured":"Upadhyay MP, Srinivasan M, Whitcher JP (2007) Microbial keratitis in the developing world: does prevention work? Int Ophthalmol Clin 47:17\u201325. doi: 10.1097\/IIO.0b013e318074e0b3","journal-title":"Int Ophthalmol Clin"},{"key":"2677_CR2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ophtha.2005.08.013","volume":"113","author":"L Keay","year":"2006","unstructured":"Keay L, Edwards K, Naduvilath T et al (2006) Microbial keratitis predisposing factors and morbidity. Ophthalmology 113:109\u2013116","journal-title":"Ophthalmology"},{"key":"2677_CR3","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1097\/QCO.0b013e328017f878","volume":"20","author":"PA Thomas","year":"2007","unstructured":"Thomas PA, Geraldine P (2007) Infectious keratitis. Curr Opin Infect Dis 20:129\u2013141. doi: 10.1097\/QCO.0b013e328017f878","journal-title":"Curr Opin Infect Dis"},{"key":"2677_CR4","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1002\/rmv.1749","volume":"23","author":"H Newman","year":"2013","unstructured":"Newman H, Gooding C (2013) Viral ocular manifestations: a broad overview. Rev Med Virol 23:281\u2013294. doi: 10.1002\/rmv.1749","journal-title":"Rev Med Virol"},{"key":"2677_CR5","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1136\/bjo.76.10.582","volume":"76","author":"D Yorston","year":"1992","unstructured":"Yorston D, Foster A (1992) Herpetic keratitis in Tanzania: association with malaria. Br J Ophthalmol 76:582\u2013585. doi: 10.1136\/bjo.76.10.582","journal-title":"Br J Ophthalmol"},{"key":"2677_CR6","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0027-9684(15)31270-0","volume":"100","author":"A Ashaye","year":"2008","unstructured":"Ashaye A, Aimola A (2008) Keratitis in children as seen in a tertiary hospital in Africa. J Natl Med Assoc 100:386\u2013390","journal-title":"J Natl Med Assoc"},{"key":"2677_CR7","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0161-6420(98)95033-3","volume":"105","author":"WG Hodge","year":"1998","unstructured":"Hodge WG, Seiff SR, Margolis TP (1998) Ocular opportunistic infection incidences among patients who are HIV positive compared to patients who are HIV negative. Ophthalmology 105:895\u2013900","journal-title":"Ophthalmology"},{"key":"2677_CR8","doi-asserted-by":"publisher","first-page":"158","DOI":"10.3109\/09286586.2011.595041","volume":"18","author":"MJ Burton","year":"2011","unstructured":"Burton MJ, Pithuwa J, Okello E et al (2011) Microbial keratitis in East Africa: why are the outcomes so poor? Ophthalmic Epidemiol 18:158\u2013163. doi: 10.3109\/09286586.2011.595041","journal-title":"Ophthalmic Epidemiol"},{"key":"2677_CR9","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1097\/00003226-199805000-00007","volume":"17","author":"GS Schwartz","year":"1998","unstructured":"Schwartz GS, Harrison AR, Holland EJ (1998) Etiology of immune stromal (interstitial) keratitis. Cornea 17:278\u2013281. doi: 10.1097\/00003226-199805000-00007","journal-title":"Cornea"},{"key":"2677_CR10","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/00004397-200604620-00005","volume":"46","author":"LK Green","year":"2006","unstructured":"Green LK, Pavan-Langston D (2006) Herpes simplex ocular inflammatory disease. Int Ophthalmol Clin 46:27\u201337. doi: 10.1097\/00004397-200604620-00005","journal-title":"Int Ophthalmol Clin"},{"key":"2677_CR11","doi-asserted-by":"publisher","first-page":"S24","DOI":"10.1016\/j.ophtha.2007.10.010","volume":"115","author":"SC Kaufman","year":"2008","unstructured":"Kaufman SC (2008) Anterior segment complications of herpes zoster ophthalmicus. Ophthalmology 115:S24\u2013S32. doi: 10.1016\/j.ophtha.2007.10.010","journal-title":"Ophthalmology"},{"key":"2677_CR12","unstructured":"The National Department of Health (2014) Standard treatment guidelines and essential medicines list for South Africa, 5th edition. The National Department of Health, Pretoria, South Africa. Available online at: http:\/\/www.up.ac.za\/media\/shared\/62\/ZP_Files\/standard-treatment-guidelines.zp66671.pdf"},{"key":"2677_CR13","volume-title":"The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines","author":"World Health Organization (WHO)","year":"2015","unstructured":"World Health Organization (WHO) (2015) The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. WHO, Geneva"},{"key":"2677_CR14","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1007\/s13365-014-0248-4","volume":"20","author":"GP Nierop van","year":"2014","unstructured":"van Nierop GP, Hintzen RQ, Verjans GM (2014) Prevalence of human Herpesviridae in cerebrospinal fluid of patients with multiple sclerosis and noninfectious neurological disease in the Netherlands. J Neurovirol 20:412\u2013418. doi: 10.1007\/s13365-014-0248-4","journal-title":"J Neurovirol"},{"key":"2677_CR15","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/1471-2415-14-43","volume":"14","author":"J Cao","year":"2014","unstructured":"Cao J, Yang Y, Yang W et al (2014) Prevalence of infectious keratitis in Central China. BMC Ophthalmol 14:43. doi: 10.1186\/1471-2415-14-43","journal-title":"BMC Ophthalmol"},{"key":"2677_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00003226-200101000-00001","volume":"20","author":"TJ Liesegang","year":"2001","unstructured":"Liesegang TJ (2001) Herpes simplex virus epidemiology and ocular importance. Cornea 20:1\u201313. doi: 10.1097\/00003226-200101000-00001","journal-title":"Cornea"},{"key":"2677_CR17","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/S0161-6420(97)30351-0","volume":"104","author":"WG Hodge","year":"1997","unstructured":"Hodge WG, Margolis TP (1997) Herpes simplex virus keratitis among patients who are positive or negative for human immunodeficiency virus: an epidemiologic study. Ophthalmology 104:120\u2013124. doi: 10.1016\/S0161-6420(97)30351-0","journal-title":"Ophthalmology"},{"key":"2677_CR18","doi-asserted-by":"publisher","first-page":"e99243","DOI":"10.1371\/journal.pone.0099243","volume":"9","author":"E Schaftenaar","year":"2014","unstructured":"Schaftenaar E, Verjans GMGM, Getu S et al (2014) High seroprevalence of human herpesviruses in HIV-infected individuals attending primary healthcare facilities in rural South Africa. PLoS One 9:e99243. doi: 10.1371\/journal.pone.0099243","journal-title":"PLoS One"},{"key":"2677_CR19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1556\/EuJMI.4.2014.1.2","volume":"4","author":"B Ghebremedhin","year":"2014","unstructured":"Ghebremedhin B (2014) Human adenovirus: Viral pathogen with increasing importance. Eur J Microbiol Immunol (Bp) 4:26\u201333. doi: 10.1556\/EuJMI.4.2014.1.2","journal-title":"Eur J Microbiol Immunol (Bp)"},{"key":"2677_CR20","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1111\/j.1444-0938.2009.00425","volume":"92","author":"UA Ubani","year":"2009","unstructured":"Ubani UA (2009) Bacteriology of external ocular infections in Aba, South Eastern Nigeria. Clin Exp Optom 92:482\u2013489. doi: 10.1111\/j.1444-0938.2009.00425","journal-title":"Clin Exp Optom"},{"key":"2677_CR21","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/S0002-9394(14)77827-4","volume":"96","author":"HM Boisjoly","year":"1983","unstructured":"Boisjoly HM, Pavan-Langston D, Kenyon KR et al (1983) Superinfections in herpes simplex keratitis. Am J Ophthalmol 96:354\u2013361. doi: 10.1016\/S0002-9394(14)77827-4","journal-title":"Am J Ophthalmol"},{"key":"2677_CR22","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1136\/bjo.79.11.1024","volume":"79","author":"M Hagan","year":"1995","unstructured":"Hagan M, Wright E, Newman M et al (1995) Causes of suppurative keratitis in Ghana. Br J Ophthalmol 79:1024\u20131028. doi: 10.1136\/bjo.79.11.1024","journal-title":"Br J Ophthalmol"},{"key":"2677_CR23","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1136\/bjo.86.8.941","volume":"86","author":"TR Poole","year":"2002","unstructured":"Poole TR, Hunter DL, Maliwa EM et al (2002) Aetiology of microbial keratitis in northern Tanzania. Br J Ophthalmol 86:941\u2013942. doi: 10.1136\/bjo.86.8.941","journal-title":"Br J Ophthalmol"},{"key":"2677_CR24","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s10384-007-0485-7","volume":"52","author":"A Kakimaru-Hasegawa","year":"2008","unstructured":"Kakimaru-Hasegawa A, Kuo CH, Komatsu N et al (2008) Clinical application of real-time polymerase chain reaction for diagnosis of herpetic diseases of the anterior segment of the eye. Jpn J Ophthalmol 52:24\u201331. doi: 10.1007\/s10384-007-0485-7","journal-title":"Jpn J Ophthalmol"},{"key":"2677_CR25","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1086\/379048","volume":"188","author":"MJ Levin","year":"2003","unstructured":"Levin MJ, Smith JG, Kaufhold RM et al (2003) Decline in varicella-zoster virus (VZV)-specific cell-mediated immunity with increasing age and boosting with a high-dose VZV vaccine. J Infect Dis 188:1336\u20131344. doi: 10.1086\/379048","journal-title":"J Infect Dis"},{"key":"2677_CR26","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1001\/archopht.120.9.1183","volume":"120","author":"T Kezuka","year":"2002","unstructured":"Kezuka T, Sakai J, Minoda H et al (2002) A relationship between varicella-zoster virus-specific delayed hypersensitivity and varicella-zoster virus-induced anterior uveitis. Arch Ophthalmol 120:1183\u20131188. doi: 10.1001\/archopht.120.9.1183","journal-title":"Arch Ophthalmol"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-016-2677-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-016-2677-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-016-2677-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T22:10:47Z","timestamp":1589667047000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-016-2677-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,28]]},"references-count":26,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["2677"],"URL":"https:\/\/doi.org\/10.1007\/s10096-016-2677-x","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,28]]}}}