{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:05:15Z","timestamp":1790845515159,"version":"4.1.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T00:00:00Z","timestamp":1524096000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["Bilateral Open Partnership Joint Research Projects"],"award-info":[{"award-number":["Bilateral Open Partnership Joint Research Projects"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1007\/s10096-018-3258-y","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T18:33:38Z","timestamp":1524162818000},"page":"1405-1410","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Recent advances in tuberculosis diagnostics in resource-limited settings"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6232-7207","authenticated-orcid":false,"given":"Mitsuko","family":"Seki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Ki","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Hayakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Mitarai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,4,19]]},"reference":[{"key":"3258_CR1","volume-title":"Global tuberculosis report 2017","author":"WHO","year":"2017","unstructured":"WHO (2017) Global tuberculosis report 2017. WHO, Geneva"},{"key":"3258_CR2","unstructured":"WHO (2012) Assessing tuberculosis under-reporting through inventory studies. In: WHO (ed)"},{"issue":"9979","key":"3258_CR3","doi-asserted-by":"publisher","first-page":"1799","DOI":"10.1016\/S0140-6736(15)60570-0","volume":"385","author":"M Uplekar","year":"2015","unstructured":"Uplekar M, Weil D, Lonnroth K, Jaramillo E, Lienhardt C, Dias HM, Falzon D, Floyd K, Gargioni G, Getahun H, Gilpin C, Glaziou P, Grzemska M, Mirzayev F, Nakatani H, Raviglione M, Programme WHGT (2015) WHO\u2019s new end TB strategy. Lancet 385(9979):1799\u20131801. https:\/\/doi.org\/10.1016\/S0140-6736(15)60570-0","journal-title":"Lancet"},{"key":"3258_CR4","volume-title":"Global tuberculosis report 2016","author":"WHO","year":"2016","unstructured":"WHO (2016) Global tuberculosis report 2016. WHO, Geneva"},{"key":"3258_CR5","unstructured":"CLSI (2008) Laboratory detection and identification of mycobacteria; approved guideline. CLSI document M48-A., vol 28. Clinical and Laboratory Standards Institute, Wayne"},{"issue":"9","key":"3258_CR6","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/S1473-3099(06)70578-3","volume":"6","author":"KR Steingart","year":"2006","unstructured":"Steingart KR, Henry M, Ng V, Hopewell PC, Ramsay A, Cunningham J, Urbanczik R, Perkins M, Aziz MA, Pai M (2006) Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis 6(9):570\u2013581. https:\/\/doi.org\/10.1016\/S1473-3099(06)70578-3","journal-title":"Lancet Infect Dis"},{"key":"3258_CR7","unstructured":"WHO (2011) Fluorescent light-emitting diode (LED) microscopy for diagnosis of tuberculosis: policy statement, Geneva"},{"issue":"5","key":"3258_CR8","doi-asserted-by":"publisher","first-page":"354","DOI":"10.2471\/BLT.06.039081","volume":"85","author":"JC Ridderhof","year":"2007","unstructured":"Ridderhof JC, van Deun A, Kam KM, Narayanan PR, Aziz MA (2007) Roles of laboratories and laboratory systems in effective tuberculosis programmes. Bull World Health Organ 85(5):354\u2013359","journal-title":"Bull World Health Organ"},{"key":"3258_CR9","doi-asserted-by":"publisher","unstructured":"Hall L, Jude KP, Clark SL, Wengenack NL (2011) Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex for first and second line drugs by broth dilution in a microtiter plate format. J Vis Exp (52). https:\/\/doi.org\/10.3791\/3094","DOI":"10.3791\/3094"},{"issue":"3","key":"3258_CR10","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1128\/JCM.23.3.582-585.1986","volume":"23","author":"S Ratnam","year":"1986","unstructured":"Ratnam S, March SB (1986) Effect of relative centrifugal force and centrifugation time on sedimentation of mycobacteria in clinical specimens. J Clin Microbiol 23(3):582\u2013585","journal-title":"J Clin Microbiol"},{"key":"3258_CR11","doi-asserted-by":"publisher","first-page":"18113","DOI":"10.1038\/srep18113","volume":"5","author":"N Horita","year":"2015","unstructured":"Horita N, Yamamoto M, Sato T, Tsukahara T, Nagakura H, Tashiro K, Shibata Y, Watanabe H, Nagai K, Nakashima K, Ushio R, Ikeda M, Sakamaki K, Yoshiyama T, Kaneko T (2015) Sensitivity and specificity of Cobas TaqMan MTB real-time polymerase chain reaction for culture-proven Mycobacterium tuberculosis: meta-analysis of 26999 specimens from 17 studies. Sci Rep 5:18113. https:\/\/doi.org\/10.1038\/srep18113","journal-title":"Sci Rep"},{"key":"3258_CR12","doi-asserted-by":"publisher","first-page":"CD009593","DOI":"10.1002\/14651858.CD009593.pub2","volume":"1","author":"KR Steingart","year":"2013","unstructured":"Steingart KR, Sohn H, Schiller I, Kloda LA, Boehme CC, Pai M, Dendukuri N (2013) Xpert(R) MTB\/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev 1:CD009593. https:\/\/doi.org\/10.1002\/14651858.CD009593.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"3258_CR13","volume-title":"Global tuberculosis report 2015","author":"WHO","year":"2015","unstructured":"WHO (2015) Global tuberculosis report 2015. WHO, Geneva"},{"key":"3258_CR14","volume-title":"Global tuberculosis report 2014","author":"WHO","year":"2014","unstructured":"WHO (2014) Global tuberculosis report 2014. WHO, Geneva"},{"key":"3258_CR15","volume-title":"Global tuberculosis report 2013","author":"WHO","year":"2013","unstructured":"WHO (2013) Global tuberculosis report 2013. WHO, Geneva"},{"key":"3258_CR16","unstructured":"Initiative GL (2017) GLI planning for country transition to Xpert MTB\/RIF Ultra cartridges"},{"key":"3258_CR17","unstructured":"FIND (2017) Report for WHO: a multicentre non-inferiority diagnostic accuracy study of the Ultra assay compared to the Xpert MTB\/RIF assay, Geneva"},{"key":"3258_CR18","unstructured":"WHO (2016) The use of loop-mediated isothermal amplification ( TB-LAMP) for the diagnosis of pulmonary tuberculosis: policy guidance. In: WHO (ed)"},{"key":"3258_CR19","doi-asserted-by":"publisher","first-page":"39090","DOI":"10.1038\/srep39090","volume":"6","author":"K Nagai","year":"2016","unstructured":"Nagai K, Horita N, Yamamoto M, Tsukahara T, Nagakura H, Tashiro K, Shibata Y, Watanabe H, Nakashima K, Ushio R, Ikeda M, Narita A, Kanai A, Sato T, Kaneko T (2016) Diagnostic test accuracy of loop-mediated isothermal amplification assay for Mycobacterium tuberculosis: systematic review and meta-analysis. Sci Rep 6:39090. https:\/\/doi.org\/10.1038\/srep39090","journal-title":"Sci Rep"},{"key":"3258_CR20","unstructured":"WHO (2015) The use of lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis and screening of active tuberculosis in people living with HIV. Policy guidance. In: WHO (ed)"},{"issue":"10","key":"3258_CR21","doi-asserted-by":"publisher","first-page":"1616","DOI":"10.1128\/CVI.05205-11","volume":"18","author":"LL Flores","year":"2011","unstructured":"Flores LL, Steingart KR, Dendukuri N, Schiller I, Minion J, Pai M, Ramsay A, Henry M, Laal S (2011) Systematic review and meta-analysis of antigen detection tests for the diagnosis of tuberculosis. Clin Vaccine Immunol 18(10):1616\u20131627. https:\/\/doi.org\/10.1128\/CVI.05205-11","journal-title":"Clin Vaccine Immunol"},{"key":"3258_CR22","doi-asserted-by":"publisher","first-page":"CD011420","DOI":"10.1002\/14651858.CD011420.pub2","volume":"5","author":"M Shah","year":"2016","unstructured":"Shah M, Hanrahan C, Wang ZY, Dendukuri N, Lawn SD, Denkinger CM, Steingart KR (2016) Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in HIV-positive adults. Cochrane Database Syst Rev 5:CD011420. https:\/\/doi.org\/10.1002\/14651858.CD011420.pub2","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"3258_CR23","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.tube.2012.04.002","volume":"92","author":"M Phillips","year":"2012","unstructured":"Phillips M, Basa-Dalay V, Blais J, Bothamley G, Chaturvedi A, Modi KD, Pandya M, Natividad MP, Patel U, Ramraje NN, Schmitt P, Udwadia ZF (2012) Point-of-care breath test for biomarkers of active pulmonary tuberculosis. Tuberculosis (Edinb) 92(4):314\u2013320. https:\/\/doi.org\/10.1016\/j.tube.2012.04.002","journal-title":"Tuberculosis (Edinb)"},{"key":"3258_CR24","doi-asserted-by":"publisher","first-page":"30617","DOI":"10.1038\/srep30617","volume":"6","author":"L Yi","year":"2016","unstructured":"Yi L, Sasaki Y, Nagai H, Ishikawa S, Takamori M, Sakashita K, Saito T, Fukushima K, Igarashi Y, Aono A, Chikamatsu K, Yamada H, Takaki A, Mori T, Mitarai S (2016) Evaluation of QuantiFERON-TB gold plus for detection of Mycobacterium tuberculosis infection in Japan. Sci Rep 6:30617. https:\/\/doi.org\/10.1038\/srep30617","journal-title":"Sci Rep"},{"issue":"37","key":"3258_CR25","doi-asserted-by":"publisher","first-page":"13664","DOI":"10.1073\/pnas.0603049103","volume":"103","author":"D Kaur","year":"2006","unstructured":"Kaur D, Berg S, Dinadayala P, Gicquel B, Chatterjee D, McNeil MR, Vissa VD, Crick DC, Jackson M, Brennan PJ (2006) Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase. Proc Natl Acad Sci U S A 103(37):13664\u201313669. https:\/\/doi.org\/10.1073\/pnas.0603049103","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"3258_CR26","doi-asserted-by":"publisher","first-page":"e81076","DOI":"10.1371\/journal.pone.0081076","volume":"8","author":"X Zhang","year":"2013","unstructured":"Zhang X, Guo J, Fan S, Li Y, Wei L, Yang X, Jiang T, Chen Z, Wang C, Liu J, Ping Z, Xu D, Wang J, Li Z, Qiu Y, Li JC (2013) Screening and identification of six serum microRNAs as novel potential combination biomarkers for pulmonary tuberculosis diagnosis. PLoS One 8(12):e81076. https:\/\/doi.org\/10.1371\/journal.pone.0081076","journal-title":"PLoS One"},{"issue":"3","key":"3258_CR27","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1097\/MCP.0000000000000161","volume":"21","author":"R McNerney","year":"2015","unstructured":"McNerney R, Zumla A (2015) Impact of the Xpert MTB\/RIF diagnostic test for tuberculosis in countries with a high burden of disease. Curr Opin Pulm Med 21(3):304\u2013308. https:\/\/doi.org\/10.1097\/MCP.0000000000000161","journal-title":"Curr Opin Pulm Med"},{"issue":"11","key":"3258_CR28","doi-asserted-by":"publisher","first-page":"e1001760","DOI":"10.1371\/journal.pmed.1001760","volume":"11","author":"HS Cox","year":"2014","unstructured":"Cox HS, Mbhele S, Mohess N, Whitelaw A, Muller O, Zemanay W, Little F, Azevedo V, Simpson J, Boehme CC, Nicol MP (2014) Impact of Xpert MTB\/RIF for TB diagnosis in a primary care clinic with high TB and HIV prevalence in South Africa: a pragmatic randomised trial. PLoS Med 11(11):e1001760. https:\/\/doi.org\/10.1371\/journal.pmed.1001760","journal-title":"PLoS Med"},{"issue":"9915","key":"3258_CR29","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/S0140-6736(13)62073-5","volume":"383","author":"G Theron","year":"2014","unstructured":"Theron G, Zijenah L, Chanda D, Clowes P, Rachow A, Lesosky M, Bara W, Mungofa S, Pai M, Hoelscher M, Dowdy D, Pym A, Mwaba P, Mason P, Peter J, Dheda K, team T-N (2014) Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB\/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial. Lancet 383(9915):424\u2013435. https:\/\/doi.org\/10.1016\/S0140-6736(13)62073-5","journal-title":"Lancet"},{"issue":"12","key":"3258_CR30","doi-asserted-by":"publisher","first-page":"e1001766","DOI":"10.1371\/journal.pmed.1001766","volume":"11","author":"B Durovni","year":"2014","unstructured":"Durovni B, Saraceni V, van den Hof S, Trajman A, Cordeiro-Santos M, Cavalcante S, Menezes A, Cobelens F (2014) Impact of replacing smear microscopy with Xpert MTB\/RIF for diagnosing tuberculosis in Brazil: a stepped-wedge cluster-randomized trial. PLoS Med 11(12):e1001766. https:\/\/doi.org\/10.1371\/journal.pmed.1001766","journal-title":"PLoS Med"},{"key":"3258_CR31","unstructured":"WHO (2003) Treatment of tuberculosis: guidelines for national programmes. In: WHO (ed)"},{"key":"3258_CR32","unstructured":"WHO (2016) WHO treatment guidelines for drug-resistant tuberculosis\u20142016 update. In: WHO (ed)"},{"issue":"5","key":"3258_CR33","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1164\/rccm.201001-0077OC","volume":"182","author":"A Deun Van","year":"2010","unstructured":"Van Deun A, Maug AK, Salim MA, Das PK, Sarker MR, Daru P, Rieder HL (2010) Short, highly effective, and inexpensive standardized treatment of multidrug-resistant tuberculosis. Am J Respir Crit Care Med 182(5):684\u2013692. https:\/\/doi.org\/10.1164\/rccm.201001-0077OC","journal-title":"Am J Respir Crit Care Med"},{"key":"3258_CR34","unstructured":"Kent PT, Kubica GP (1985) A guide for level III In: Laboratory public health mycobacteriology. Centers for Disease Control, US Dept of Public Health and Human Services, Atlanta, Ga, pp 31\u201356"},{"issue":"3","key":"3258_CR35","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.ijmyco.2015.05.014","volume":"4","author":"S Yoshimatsu","year":"2015","unstructured":"Yoshimatsu S, Kato-Matsumaru T, Aono A, Chikamatsu K, Yamada H, Mitarai S (2015) Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads. Int J Mycobacteriol 4(3):245\u2013249. https:\/\/doi.org\/10.1016\/j.ijmyco.2015.05.014","journal-title":"Int J Mycobacteriol"},{"issue":"Suppl 3","key":"3258_CR36","doi-asserted-by":"publisher","first-page":"S141","DOI":"10.1093\/cid\/civ610","volume":"61","author":"AM Starks","year":"2015","unstructured":"Starks AM, Aviles E, Cirillo DM, Denkinger CM, Dolinger DL, Emerson C, Gallarda J, Hanna D, Kim PS, Liwski R, Miotto P, Schito M, Zignol M (2015) Collaborative effort for a centralized worldwide tuberculosis relational sequencing data platform. Clin Infect Dis 61(Suppl 3):S141\u2013S146. https:\/\/doi.org\/10.1093\/cid\/civ610","journal-title":"Clin Infect Dis"},{"issue":"22","key":"3258_CR37","doi-asserted-by":"publisher","first-page":"2991","DOI":"10.1093\/bioinformatics\/bts544","volume":"28","author":"F Coll","year":"2012","unstructured":"Coll F, Mallard K, Preston MD, Bentley S, Parkhill J, McNerney R, Martin N, Clark TG (2012) SpolPred: rapid and accurate prediction of Mycobacterium tuberculosis spoligotypes from short genomic sequences. Bioinformatics 28(22):2991\u20132993. https:\/\/doi.org\/10.1093\/bioinformatics\/bts544","journal-title":"Bioinformatics"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-018-3258-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-018-3258-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-018-3258-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:59:32Z","timestamp":1604192372000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-018-3258-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,19]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["3258"],"URL":"https:\/\/doi.org\/10.1007\/s10096-018-3258-y","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,19]]},"assertion":[{"value":"9 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 April 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"For this type of paper, formal consent does not apply.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"For this type of paper, informed consent does not apply.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}