{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:26:02Z","timestamp":1740108362689,"version":"3.37.3"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T00:00:00Z","timestamp":1557878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005297","name":"Uniwersytet Medyczny w Bialymstoku","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005297","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1007\/s10096-019-03569-0","type":"journal-article","created":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T19:46:17Z","timestamp":1557949577000},"page":"1443-1447","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Enteroviral meningitis reduces CSF concentration of A\u03b242, but does not affect markers of parenchymal damage"],"prefix":"10.1007","volume":"38","author":[{"given":"Kacper","family":"Toczylowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malgorzata","family":"Wojtkowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8391-4793","authenticated-orcid":false,"given":"Artur","family":"Sulik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,5,15]]},"reference":[{"key":"3569_CR1","doi-asserted-by":"publisher","first-page":"3216","DOI":"10.1096\/fj.201700360","volume":"31","author":"RF Itzhaki","year":"2017","unstructured":"Itzhaki RF (2017) Herpes simplex virus type 1 and Alzheimer\u2019s disease: possible mechanisms and signposts. FASEB J 31:3216\u20133226","journal-title":"FASEB J"},{"key":"3569_CR2","doi-asserted-by":"publisher","first-page":"2324","DOI":"10.1212\/WNL.0000000000003391","volume":"87","author":"X Zhan","year":"2016","unstructured":"Zhan X, Stamova B, Jin L-W, DeCarli C, Phinney B, Sharp FR (2016) Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology 87:2324\u20132332","journal-title":"Neurology"},{"key":"3569_CR3","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0165-0173(00)00019-9","volume":"33","author":"L Bu\u00e9e","year":"2000","unstructured":"Bu\u00e9e L, Bussi\u00e8re T, Bu\u00e9e-Scherrer V, Delacourte A, Hof PR (2000) Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res Brain Res Rev 33:95\u2013130","journal-title":"Brain Res Brain Res Rev"},{"key":"3569_CR4","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.trci.2018.06.014","volume":"4","author":"JW Kinney","year":"2018","unstructured":"Kinney JW, Bemiller SM, Murtishaw AS, Leisgang AM, Salazar AM, Lamb BT (2018) Inflammation as a central mechanism in Alzheimer\u2019s disease. Alzheimers Dement (N Y) 4:575\u2013590","journal-title":"Alzheimers Dement (N Y)"},{"key":"3569_CR5","doi-asserted-by":"publisher","unstructured":"Ashraf GM, Tarasov VV, Makhmutov\u0430 A, Chubarev VN, Avila-Rodriguez M, Bachurin SO, Aliev G (2018) The possibility of an infectious etiology of Alzheimer disease. Mol Neurobiol. https:\/\/doi.org\/10.1007\/s12035-018-1388-y","DOI":"10.1007\/s12035-018-1388-y"},{"key":"3569_CR6","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1093\/cid\/cix540","volume":"65","author":"UK Rohlwink","year":"2017","unstructured":"Rohlwink UK, Mauff K, Wilkinson KA, Enslin N, Wegoye E, Wilkinson RJ, Figaji AA (2017) Biomarkers of cerebral injury and inflammation in pediatric tuberculous meningitis. Clin Infect Dis 65:1298\u20131307","journal-title":"Clin Infect Dis"},{"key":"3569_CR7","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1742-2094-7-6","volume":"7","author":"ML Chaves","year":"2010","unstructured":"Chaves ML, Camozzato AL, Ferreira ED, Piazenski I, Kochhann R, Dall\u2019Igna O, Mazzini GS, Souza DO, Portela LV (2010) Serum levels of S100B and NSE proteins in Alzheimer\u2019s disease patients. J Neuroinflammation 7:6","journal-title":"J Neuroinflammation"},{"key":"3569_CR8","doi-asserted-by":"publisher","first-page":"8453","DOI":"10.1097\/MD.0000000000008453","volume":"96","author":"A Alshweki","year":"2017","unstructured":"Alshweki A, P\u00e9rez-Mu\u00f1uzuri A, L\u00f3pez-Su\u00e1rez O, Ba\u00f1a A, Couce ML (2017) Relevance of urinary S100B protein levels as a short-term prognostic biomarker in asphyxiated infants treated with hypothermia. Medicine (Baltimore) 96:8453","journal-title":"Medicine (Baltimore)"},{"key":"3569_CR9","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1007\/s00415-012-6688-y","volume":"260","author":"JJ Krut","year":"2013","unstructured":"Krut JJ, Zetterberg H, Blennow K, Cinque P, Hagberg L, Price RW, Studahl M, Gissl\u00e9n M (2013) Cerebrospinal fluid Alzheimer\u2019s biomarker profiles in CNS infections. J Neurol 260:620\u2013626","journal-title":"J Neurol"},{"key":"3569_CR10","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0304-3940(01)02285-6","volume":"314","author":"M Sj\u00f6gren","year":"2001","unstructured":"Sj\u00f6gren M, Gissl\u00e9n M, Vanmechelen E, Blennow K (2001) Low cerebrospinal fluid beta-amyloid 42 in patients with acute bacterial meningitis and normalization after treatment. Neurosci Lett 314:33\u201336","journal-title":"Neurosci Lett"},{"key":"3569_CR11","doi-asserted-by":"publisher","first-page":"152","DOI":"10.3389\/fnagi.2018.00152","volume":"10","author":"P Spitzer","year":"2018","unstructured":"Spitzer P, Lang R, Oberstein TJ, Lewczuk P, Ermann N, Huttner HB, Masouris I, Kornhuber J, K\u00f6del U, Maler JM (2018) A specific reduction in A\u03b21-42 vs. a universal loss of A\u03b2 peptides in CSF differentiates Alzheimer\u2019s disease from meningitis and multiple sclerosis. Front Aging Neurosci 10:152","journal-title":"Front Aging Neurosci"},{"key":"3569_CR12","doi-asserted-by":"publisher","first-page":"32228","DOI":"10.1038\/srep32228","volume":"6","author":"P Spitzer","year":"2016","unstructured":"Spitzer P, Condic M, Herrmann M et al (2016) Amyloidogenic amyloid-\u03b2-peptide variants induce microbial agglutination and exert antimicrobial activity. Sci Rep 6:32228","journal-title":"Sci Rep"},{"key":"3569_CR13","doi-asserted-by":"publisher","first-page":"9505","DOI":"10.1371\/journal.pone.0009505","volume":"5","author":"SJ Soscia","year":"2010","unstructured":"Soscia SJ, Kirby JE, Washicosky KJ et al (2010) The Alzheimer\u2019s disease-associated amyloid beta-protein is an antimicrobial peptide. PLoS One 5:9505","journal-title":"PLoS One"},{"key":"3569_CR14","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0304-3940(01)01556-7","volume":"300","author":"SD S\u00fcssmuth","year":"2001","unstructured":"S\u00fcssmuth SD, Reiber H, Tumani H (2001) Tau protein in cerebrospinal fluid (CSF): a blood-CSF barrier related evaluation in patients with various neurological diseases. Neurosci Lett 300:95\u201398","journal-title":"Neurosci Lett"},{"key":"3569_CR15","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/j.bbi.2016.09.027","volume":"60","author":"LE Collins-Praino","year":"2017","unstructured":"Collins-Praino LE, Corrigan F (2017) Does neuroinflammation drive the relationship between tau hyperphosphorylation and dementia development following traumatic brain injury? Brain Behav Immun 60:369\u2013382","journal-title":"Brain Behav Immun"},{"key":"3569_CR16","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1159\/000330566","volume":"66","author":"K Jung","year":"2011","unstructured":"Jung K, Goerdt C, Lange P, Blocher J, Djukic M, Gerber J, Spreer A, Nau R, Otto M, Schmidt H (2011) The use of S100B and tau protein concentrations in the cerebrospinal fluid for the differential diagnosis of bacterial meningitis: a retrospective analysis. Eur Neurol 66:128\u2013132","journal-title":"Eur Neurol"},{"key":"3569_CR17","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/1471-2377-10-51","volume":"10","author":"N Mattsson","year":"2010","unstructured":"Mattsson N, Bremell D, Anckars\u00e4ter R, Blennow K, Anckars\u00e4ter H, Zetterberg H, Hagberg L (2010) Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism. BMC Neurol 10:51","journal-title":"BMC Neurol"},{"key":"3569_CR18","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1373\/clinchem.2003.021048","volume":"50","author":"D Gazzolo","year":"2004","unstructured":"Gazzolo D, Grutzfeld D, Michetti F, Toesca A, Lituania M, Bruschettini M, Dobrzanska A, Bruschettini P (2004) Increased S100B in cerebrospinal fluid of infants with bacterial meningitis: relationship to brain damage and routine cerebrospinal fluid findings. Clin Chem 50:941\u2013944","journal-title":"Clin Chem"},{"key":"3569_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/00207454.2015.1135334","volume":"127","author":"Q-L Peng","year":"2017","unstructured":"Peng Q-L, Tao S-H, Yu N, Zhou X-Z, Peng Y-Z, Fu N (2017) Elevated levels of cerebrospinal fluid S100B are associated with brain injury and unfavorable outcomes in children with central nervous system infections. Int J Neurosci 127:1\u20139","journal-title":"Int J Neurosci"},{"key":"3569_CR20","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1542\/peds.105.2.316","volume":"105","author":"B Negrini","year":"2000","unstructured":"Negrini B, Kelleher KJ, Wald ER (2000) Cerebrospinal fluid findings in aseptic versus bacterial meningitis. Pediatrics 105:316\u2013319","journal-title":"Pediatrics"},{"key":"3569_CR21","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.exger.2015.03.002","volume":"65","author":"LA Hohsfield","year":"2015","unstructured":"Hohsfield LA, Humpel C (2015) Migration of blood cells to \u03b2-amyloid plaques in Alzheimer\u2019s disease. Exp Gerontol 65:8\u201315","journal-title":"Exp Gerontol"},{"key":"3569_CR22","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.jalz.2013.12.023","volume":"10","author":"FH Duits","year":"2014","unstructured":"Duits FH, Teunissen CE, Bouwman FH et al (2014) The cerebrospinal fluid \u201cAlzheimer profile\u201d: easily said, but what does it mean? Alzheimers Dement 10:713\u2013723 e2","journal-title":"Alzheimers Dement"},{"key":"3569_CR23","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1001\/jamaneurol.2013.48","volume":"70","author":"M Handoko","year":"2013","unstructured":"Handoko M, Grant M, Kuskowski M, Zahs KR, Wallin A, Blennow K, Ashe KH (2013) Correlation of specific amyloid-\u03b2 oligomers with tau in cerebrospinal fluid from cognitively normal older adults. JAMA Neurol 70:594\u2013599","journal-title":"JAMA Neurol"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-019-03569-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-019-03569-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-019-03569-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T23:31:35Z","timestamp":1607815895000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-019-03569-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,15]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["3569"],"URL":"https:\/\/doi.org\/10.1007\/s10096-019-03569-0","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"type":"print","value":"0934-9723"},{"type":"electronic","value":"1435-4373"}],"subject":[],"published":{"date-parts":[[2019,5,15]]},"assertion":[{"value":"19 March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The study protocol was approved by the Research Ethics Committee of our institution. An informed written consent was obtained from all the children\u2019s parents or legal guardians.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors have read and approved the final manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}