{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:26:27Z","timestamp":1775093187247,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T00:00:00Z","timestamp":1577145600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T00:00:00Z","timestamp":1577145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100005856","name":"Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa","doi-asserted-by":"publisher","award":["PTDC\/DTP-EPI\/0842\/2014"],"award-info":[{"award-number":["PTDC\/DTP-EPI\/0842\/2014"]}],"id":[{"id":"10.13039\/501100005856","id-type":"DOI","asserted-by":"publisher"}]},{"name":"COMPETE2020 - Programa Operacional Competitividade e Internacionaliza\u00e7\u00e3o","award":["LISBOA-01-0145-FEDER-007660"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-007660"]}]},{"DOI":"10.13039\/501100012527","name":"Centro de Investiga\u00e7\u00e3o em Ci\u00eancias Sociais","doi-asserted-by":"crossref","award":["LISBOA-01-0145-FEDER-016417"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-016417"]}],"id":[{"id":"10.13039\/501100012527","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["FNS-31003A_163432"],"award-info":[{"award-number":["FNS-31003A_163432"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["FNS-407240_177381"],"award-info":[{"award-number":["FNS-407240_177381"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s10096-019-03798-3","type":"journal-article","created":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T01:02:32Z","timestamp":1577149352000},"page":"783-790","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Intestinal carriage of extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae at admission in a Portuguese hospital"],"prefix":"10.1007","volume":"39","author":[{"given":"Marta","family":"Aires-de-Sousa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizeth","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Lu\u00edsa","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Lu\u00edsa","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augusto","family":"Machado e Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herm\u00ednia","family":"de Lencastre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Poirel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,24]]},"reference":[{"issue":"4","key":"3798_CR1","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1128\/CMR.18.4.657-686.2005","volume":"18","author":"DL Paterson","year":"2005","unstructured":"Paterson DL, Bonomo RA (2005) Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev 18(4):657\u2013686","journal-title":"Clin Microbiol Rev"},{"issue":"4","key":"3798_CR2","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1128\/CMR.00023-13","volume":"26","author":"PL Woerther","year":"2013","unstructured":"Woerther PL, Burdet C, Chachaty E, Andremont A (2013) Trends in human fecal carriage of extended-spectrum beta-lactamases in the community: toward the globalization of CTX-M. Clin Microbiol Rev 26(4):744\u2013758","journal-title":"Clin Microbiol Rev"},{"issue":"suppl_1","key":"3798_CR3","doi-asserted-by":"publisher","first-page":"S44","DOI":"10.1093\/jtm\/taw102","volume":"24","author":"Y Doi","year":"2017","unstructured":"Doi Y, Iovleva A, Bonomo RA (2017) The ecology of extended-spectrum beta-lactamases (ESBLs) in the developed world. J Travel Med 24(suppl_1):S44\u2013S51","journal-title":"J Travel Med"},{"key":"3798_CR4","unstructured":"ECDC (2018) Surveillance of antimicrobial resistance in Europe \u2013 annual report of the European Antimicrobial Resistance Surveillance Network (EARS-net) 2017, Stockholm, EARS-Net-report-2017-update-jan-2019pdf Cited April 10, 2019"},{"issue":"3","key":"3798_CR5","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1093\/cid\/ciw283","volume":"63","author":"S Karanika","year":"2016","unstructured":"Karanika S, Karantanos T, Arvanitis M, Grigoras C, Mylonakis E (2016) Fecal colonization with extended-spectrum beta-lactamase-producing Enterobacteriaceae and risk factors among healthy individuals: a systematic review and metaanalysis. Clin Infect Dis 63(3):310\u2013318","journal-title":"Clin Infect Dis"},{"issue":"8","key":"3798_CR6","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.1016\/j.ijmm.2014.08.003","volume":"304","author":"C Rodrigues","year":"2014","unstructured":"Rodrigues C, Machado E, Ramos H, Peixe L, Novais A (2014) Expansion of ESBL-producing Klebsiella pneumoniae in hospitalized patients: a successful story of international clones (ST15, ST147, ST336) and epidemic plasmids (IncR, IncFIIK). Int J Med Microbiol 304(8):1100\u20131108","journal-title":"Int J Med Microbiol"},{"issue":"6","key":"3798_CR7","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1128\/AAC.01412-06","volume":"51","author":"N Mendonca","year":"2007","unstructured":"Mendonca N, Leitao J, Manageiro V, Ferreira E, Canica M (2007) Spread of extended-spectrum beta-lactamase CTX-M-producing Escherichia coli clinical isolates in community and nosocomial environments in Portugal. Antimicrob Agents Chemother 51(6):1946\u20131955","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"3798_CR8","doi-asserted-by":"publisher","first-page":"3003","DOI":"10.1128\/JCM.00977-15","volume":"53","author":"L Poirel","year":"2015","unstructured":"Poirel L, Nordmann P (2015) Rapidec Carba NP test for rapid detection of carbapenemase producers. J Clin Microbiol 53(9):3003\u20133008","journal-title":"J Clin Microbiol"},{"issue":"9","key":"3798_CR9","doi-asserted-by":"publisher","first-page":"3016","DOI":"10.1128\/JCM.00859-12","volume":"50","author":"P Nordmann","year":"2012","unstructured":"Nordmann P, Dortet L, Poirel L (2012) Rapid detection of extended-spectrum-beta-lactamase-producing Enterobacteriaceae. J Clin Microbiol 50(9):3016\u20133022","journal-title":"J Clin Microbiol"},{"key":"3798_CR10","doi-asserted-by":"crossref","unstructured":"Ortiz de la Rosa JM, Nordmann P, Poirel L (2019) ESBLs and resistance to ceftazidime\/avibactam and ceftolozane\/tazobactam combinations in Escherichia coli and Pseudomonas aeruginosa. J Antimicrob Chemother In press","DOI":"10.1093\/jac\/dkz149"},{"issue":"1","key":"3798_CR11","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.diagmicrobio.2010.12.002","volume":"70","author":"L Poirel","year":"2011","unstructured":"Poirel L, Walsh TR, Cuvillier V, Nordmann P (2011) Multiplex PCR for detection of acquired carbapenemase genes. Diagn Microbiol Infect Dis 70(1):119\u2013123","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"2","key":"3798_CR12","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1093\/jac\/dkm204","volume":"60","author":"V Cattoir","year":"2007","unstructured":"Cattoir V, Poirel L, Rotimi V, Soussy CJ, Nordmann P (2007) Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J Antimicrob Chemother 60(2):394\u2013397","journal-title":"J Antimicrob Chemother"},{"issue":"10","key":"3798_CR13","doi-asserted-by":"publisher","first-page":"6189","DOI":"10.1128\/AAC.01201-16","volume":"60","author":"N Kieffer","year":"2016","unstructured":"Kieffer N, Nordmann P, Aires-de-Sousa M, Poirel L (2016) High prevalence of carbapenemase-producing Enterobacteriaceae among hospitalized children in Luanda, Angola. Antimicrob Agents Chemother 60(10):6189\u20136192","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"3798_CR14","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.mimet.2005.03.018","volume":"63","author":"A Carattoli","year":"2005","unstructured":"Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ (2005) Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 63(3):219\u2013228","journal-title":"J Microbiol Methods"},{"issue":"4","key":"3798_CR15","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1093\/jac\/dkv443","volume":"71","author":"C Rodrigues","year":"2016","unstructured":"Rodrigues C, Machado E, Fernandes S, Peixe L, Novais A (2016) An update on faecal carriage of ESBL-producing Enterobacteriaceae by Portuguese healthy humans: detection of the H30 subclone of B2-ST131 Escherichia coli producing CTX-M-27. J Antimicrob Chemother 71(4):1120\u20131122","journal-title":"J Antimicrob Chemother"},{"issue":"10","key":"3798_CR16","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1016\/j.cmi.2019.02.026","volume":"25","author":"JA Otter","year":"2019","unstructured":"Otter JA, Natale A, Batra R, Tosas Auguet O, Dyakova E, Goldenberg SD, Edgeworth JD (2019) Individual- and community-level risk factors for ESBL Enterobacteriaceae colonization identified by universal admission screening in London. Clin Microbiol Infect 25(10):1259\u20131265","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"3798_CR17","doi-asserted-by":"publisher","first-page":"e024879","DOI":"10.1136\/bmjopen-2018-024879","volume":"9","author":"C Diaz-Agero Perez","year":"2019","unstructured":"Diaz-Agero Perez C, Lopez-Fresnena N, Rincon Carlavilla AL, Hernandez Garcia M, Ruiz-Garbajosa P, Aranaz-Andres JM, Maechler F, Gastmeier P, Bonten MJM, Canton R (2019) Local prevalence of extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae intestinal carriers at admission and co-expression of ESBL and OXA-48 carbapenemase in Klebsiella pneumoniae: a prevalence survey in a Spanish University Hospital. BMJ Open 9(3):e024879","journal-title":"BMJ Open"},{"issue":"10","key":"3798_CR18","doi-asserted-by":"publisher","first-page":"2957","DOI":"10.1093\/jac\/dkw216","volume":"71","author":"A Hamprecht","year":"2016","unstructured":"Hamprecht A, Rohde AM, Behnke M, Feihl S, Gastmeier P, Gebhardt F, Kern WV, Knobloch JK, Mischnik A, Obermann B, Querbach C, Peter S, Schneider C, Schroder W, Schwab F, Tacconelli E, Wiese-Posselt M, Wille T, Willmann M, Seifert H, Zweigner J, Group D-AS (2016) Colonization with third-generation cephalosporin-resistant Enterobacteriaceae on hospital admission: prevalence and risk factors. J Antimicrob Chemother 71(10):2957\u20132963","journal-title":"J Antimicrob Chemother"},{"issue":"2","key":"3798_CR19","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.cmi.2014.09.014","volume":"21","author":"TN Platteel","year":"2015","unstructured":"Platteel TN, Leverstein-van Hall MA, Cohen Stuart JW, Thijsen SF, Mascini EM, van Hees BC, Scharringa J, Fluit AC, Bonten MJ (2015) Predicting carriage with extended-spectrum beta-lactamase-producing bacteria at hospital admission: a cross-sectional study. Clin Microbiol Infect 21(2):141\u2013146","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"3798_CR20","doi-asserted-by":"publisher","first-page":"e0208505","DOI":"10.1371\/journal.pone.0208505","volume":"14","author":"S Hagel","year":"2019","unstructured":"Hagel S, Makarewicz O, Hartung A, Weiss D, Stein C, Brandt C, Schumacher U, Ehricht R, Patchev V, Pletz MW (2019) ESBL colonization and acquisition in a hospital population: the molecular epidemiology and transmission of resistance genes. PLoS One 14(1):e0208505","journal-title":"PLoS One"},{"issue":"1","key":"3798_CR21","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1128\/AAC.49.1.477-478.2005","volume":"49","author":"T Conceicao","year":"2005","unstructured":"Conceicao T, Brizio A, Duarte A, Lito LM, Cristino JM, Salgado MJ (2005) First description of CTX-M-15-producing Klebsiella pneumoniae in Portugal. Antimicrob Agents Chemother 49(1):477\u2013478","journal-title":"Antimicrob Agents Chemother"},{"issue":"6","key":"3798_CR22","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1007\/s12275-014-3420-x","volume":"52","author":"D Jones-Dias","year":"2014","unstructured":"Jones-Dias D, Manageiro V, Ferreira E, Louro D, ARSPiPA participants, Canica M (2014) Diversity of extended-spectrum and plasmid-mediated AmpC beta-lactamases in Enterobacteriaceae isolates from Portuguese health care facilities. J Microbiol 52(6):496\u2013503","journal-title":"J Microbiol"},{"key":"3798_CR23","first-page":"782897","volume":"2014","author":"R Fernandes","year":"2014","unstructured":"Fernandes R, Amador P, Oliveira C, Prudencio C (2014) Molecular characterization of ESBL-producing Enterobacteriaceae in northern Portugal. ScientificWorldJournal 2014:782897","journal-title":"ScientificWorldJournal"},{"key":"3798_CR24","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.jgar.2016.08.001","volume":"7","author":"D Goncalves","year":"2016","unstructured":"Goncalves D, Cecilio P, Ferreira H (2016) Nursing homes and long-term care facilities: reservoirs of CTX-M-15-producing Escherichia coli O25b-ST131 in Portugal. J Glob Antimicrob Resist 7:69\u201371","journal-title":"J Glob Antimicrob Resist"},{"key":"3798_CR25","doi-asserted-by":"crossref","unstructured":"Fournier C, Aires-de-Sousa M, Nordmann P, Poirel L (2019) Occurrence of CTX-M-15 and MCR-1-producing Enterobacterales in pigs, Portugal; evidences of direct links with antibiotic selective pressure. Int J Antimicrob Agents In press","DOI":"10.1016\/j.ijantimicag.2019.09.006"},{"issue":"14","key":"3798_CR26","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1007\/s40265-019-01180-3","volume":"79","author":"G Peirano","year":"2019","unstructured":"Peirano G, Pitout JDD (2019) Extended-spectrum beta-lactamase-producing Enterobacteriaceae: update on molecular epidemiology and treatment options. Drugs 79(14):1529\u20131541","journal-title":"Drugs"},{"key":"3798_CR27","doi-asserted-by":"crossref","unstructured":"Poirel L, Ortiz de la Rosa JM, Richard A, Aires-de-Sousa M, Nordmann P (2019) CTX-M-33, a CTX-M-15 derivative conferring reduced susceptibility to carbapenems. Antimicrob Agents Chemother In press","DOI":"10.1128\/AAC.01515-19"},{"issue":"5","key":"3798_CR28","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.ijantimicag.2006.11.010","volume":"29","author":"I Galani","year":"2007","unstructured":"Galani I, Souli M, Chryssouli Z, Giamarellou H (2007) Detection of CTX-M-15 and CTX-M-33, a novel variant of CTX-M-15, in clinical Escherichia coli isolates in Greece. Int J Antimicrob Agents 29(5):598\u2013600","journal-title":"Int J Antimicrob Agents"},{"issue":"12","key":"3798_CR29","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1292\/jvms.14-0274","volume":"76","author":"SW Yi","year":"2014","unstructured":"Yi SW, Chung TH, Joh SJ, Park C, Park BY, Shin GW (2014) High prevalence of blaCTX-M group genes in Aeromonas dhakensis isolated from aquaculture fish species in South Korea. J Vet Med Sci 76(12):1589\u20131593","journal-title":"J Vet Med Sci"},{"key":"3798_CR30","doi-asserted-by":"crossref","unstructured":"Pitout JD, DeVinney R (2017) Escherichia coli ST131: a multidrug-resistant clone primed for global domination. F1000Res 6","DOI":"10.12688\/f1000research.10609.1"},{"issue":"1","key":"3798_CR31","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1136\/ewjm.176.1.51","volume":"176","author":"T Jancel","year":"2002","unstructured":"Jancel T, Dudas V (2002) Management of uncomplicated urinary tract infections. West J Med 176(1):51\u201355","journal-title":"West J Med"},{"issue":"1","key":"3798_CR32","doi-asserted-by":"publisher","first-page":"67","DOI":"10.3947\/ic.2018.50.1.67","volume":"50","author":"CI Kang","year":"2018","unstructured":"Kang CI, Kim J, Park DW, Kim BN, Ha US, Lee SJ, Yeo JK, Min SK, Lee H, Wie SH (2018) Clinical practice guidelines for the antibiotic treatment of community-acquired urinary tract infections. Infect Chemother 50(1):67\u2013100","journal-title":"Infect Chemother"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-019-03798-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-019-03798-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-019-03798-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T00:04:41Z","timestamp":1608681881000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-019-03798-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,24]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["3798"],"URL":"https:\/\/doi.org\/10.1007\/s10096-019-03798-3","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,24]]},"assertion":[{"value":"26 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}