{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T01:59:02Z","timestamp":1775613542051,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T00:00:00Z","timestamp":1578873600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T00:00:00Z","timestamp":1578873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1007\/s10096-019-03810-w","type":"journal-article","created":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T05:48:26Z","timestamp":1578894506000},"page":"955-963","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Urinary tract infections in children <\u20092\u00a0years of age hospitalized in a tertiary medical center in Southern Israel: epidemiologic, imaging, and microbiologic characteristics of first episode in life"],"prefix":"10.1007","volume":"39","author":[{"given":"David","family":"Shaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Hodik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siham","family":"Elamour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raouf","family":"Nassar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eyal","family":"Kristal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Leibovitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Horev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Leibovitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,1,13]]},"reference":[{"key":"3810_CR1","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1097\/01.inf.0000147367.42167.f9","volume":"23","author":"KB Roberts","year":"2004","unstructured":"Roberts KB (2004) Urinary tract infection treatment and evaluation. Update. Pediatr Infect Dis J 23:1163\u20131164","journal-title":"Pediatr Infect Dis J"},{"key":"3810_CR2","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1097\/INF.0b013e31815e4122","volume":"27","author":"N Shaikh","year":"2008","unstructured":"Shaikh N, Morone NE, Bost JE, Farrell MH (2008) Prevalence of urinary tract infection in childhood: a meta-analysis. Pediatr Infect Dis J 27:302\u2013308","journal-title":"Pediatr Infect Dis J"},{"key":"3810_CR3","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1542\/peds.2011-2107B","volume":"128","author":"American Academy of Pediatrics","year":"2011","unstructured":"American Academy of Pediatrics (2011) Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months. Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management. Pediatrics 128:595\u2013610","journal-title":"Pediatrics"},{"key":"3810_CR4","doi-asserted-by":"publisher","first-page":"e749","DOI":"10.1542\/peds.2011-1332","volume":"128","author":"SME Finnel","year":"2011","unstructured":"Finnel SME, Carroll AE, Downs SM (2011) Technical report-diagnosis and management of an initial UTI in febrile infants and young children. American Academy of Pediatrics. Pediatrics 128:e749\u2013e770","journal-title":"Pediatrics"},{"key":"3810_CR5","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1097\/00008480-200402000-00016","volume":"16","author":"TA Schlager","year":"2004","unstructured":"Schlager TA (2004) Urinary tract infections in infants and children: a comprehensive overview. Curr Opin Pediatr 16:85\u201388","journal-title":"Curr Opin Pediatr"},{"key":"3810_CR6","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3109\/14767058.2010.513851","volume":"23","author":"L Cataldi","year":"2010","unstructured":"Cataldi L, Zaffanello M, Gnarra M, Fanos V (2010) Urinary tract infection in the newborn and the infant: state of the art. J Mater Fetal Neonatal Med 23:90\u201393","journal-title":"J Mater Fetal Neonatal Med"},{"key":"3810_CR7","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1097\/INF.0b013e318204dcf3","volume":"30","author":"K Ismaili","year":"2011","unstructured":"Ismaili K, Wissing KM, Lolin K, Le PQ, Cristophe C, Lepage P et al (2011) Characteristics of first urinary tract infection with fever in children\u2014a prospective clinical and imaging study. Pediatr Infect Dis J 30:371\u2013374","journal-title":"Pediatr Infect Dis J"},{"key":"3810_CR8","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.jpeds.2010.06.053","volume":"58","author":"K Ismaili","year":"2011","unstructured":"Ismaili K, Lolin K, Damry N, Alexander M, Lepage P, Hall M (2011) Febrile urinary tract infection in 0-to-3-month-old infants: a prospective follow-up study. J Pediatr 58:91\u201394","journal-title":"J Pediatr"},{"key":"3810_CR9","doi-asserted-by":"publisher","first-page":"e20163026","DOI":"10.1542\/peds.2016-3026","volume":"138","author":"American Academy of Pediatrics","year":"2016","unstructured":"American Academy of Pediatrics (2016) Subcommittee on urinary tract infection. Reaffirmation of AAP clinical practice guideline: the diagnosis and management of the initial urinary tract infection in febrile and children 2\u201324 months of age. Pediatrics 138:e20163026","journal-title":"Pediatrics"},{"key":"3810_CR10","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0732-8893(98)00158-8","volume":"35","author":"RN Jones","year":"1999","unstructured":"Jones RN, Kugler KC, Pfaller MA, Winokur PL (1999) Characteristics of pathogens causing urinary tract infections in hospitals in North America: results from the SENTRY Antimicrobial Surveillance Program. Diagn Microbiol Infect Dis 35:55\u201363","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"Suppl 1A","key":"3810_CR11","doi-asserted-by":"publisher","first-page":"29S","DOI":"10.1016\/S0002-9343(02)01057-4","volume":"113","author":"K Gupta","year":"2002","unstructured":"Gupta K (2002) Addressing antibiotic resistance. Am J Med 113(Suppl 1A):29S\u201334S","journal-title":"Am J Med"},{"key":"3810_CR12","first-page":"94","volume":"46","author":"DJ Farrell","year":"2003","unstructured":"Farrell DJ, Morrissey I, De Rubeis D, Robbins M, Felmingham D (2003) A UK multicentre study of the antimicrobial susceptibility of bacterial pathogens causing urinary tract infection. J Inf Secur 46:94\u2013100","journal-title":"J Inf Secur"},{"key":"3810_CR13","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/j.ijantimicag.2006.08.009","volume":"28","author":"S Y\u00fcksel","year":"2006","unstructured":"Y\u00fcksel S, Ozt\u00fcrk B, Kavaz A, Oz\u00e7akar ZB, Acar B, G\u00fcriz H et al (2006) Antibiotic resistance of urinary tract pathogens and evaluation of empirical treatment in Turkish children with urinary tract infections. Int J Antimicrob Agents 28:413\u2013416","journal-title":"Int J Antimicrob Agents"},{"key":"3810_CR14","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.1136\/bmj\/1939","volume":"352","author":"A Bryce","year":"2016","unstructured":"Bryce A, Hay AD, Lane IF, Thornton HV, Wootton M, Costelloe C (2016) Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis. BMJ 352:1939. https:\/\/doi.org\/10.1136\/bmj\/1939","journal-title":"BMJ"},{"key":"3810_CR15","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1097\/00006454-199110000-00005","volume":"10","author":"S Ashkenazi","year":"1991","unstructured":"Ashkenazi S, Even-Tov S, Samra Z, Dinari G (1991) Uropathogens of various childhood populations and their antibiotic susceptibility. Pediatr Infect Dis J 10:742\u2013746","journal-title":"Pediatr Infect Dis J"},{"key":"3810_CR16","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1097\/01.inf.0000168743.57286.13","volume":"24","author":"N Marcus","year":"2005","unstructured":"Marcus N, Ashkenazi S, Yaari A, Samra Z, Livni G (2005) Non-Escherichia coli versus Escherichia coli community-acquired urinary tract infections in children hospitalized in a tertiary center: relative frequency, risk factors, antimicrobial resistance and outcome. Pediatr Infect Dis J 24:581\u2013585","journal-title":"Pediatr Infect Dis J"},{"key":"3810_CR17","doi-asserted-by":"publisher","unstructured":"Gurevich E, Tchernin D, Schreyber R, Muller R, Leibovitz E (2015) Follow-up after infants younger than 2 months of age with urinary tract infection in Southern Israel: epidemiologic, microbiologic and disease recurrence characteristics. Braz J Infect Dis. https:\/\/doi.org\/10.1016\/j.bjid2015.09.003","DOI":"10.1016\/j.bjid2015.09.003"},{"key":"3810_CR18","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1007\/s00431-014-2459-3","volume":"174","author":"I Alberici","year":"2015","unstructured":"Alberici I, Bayazit AK, Drozdz D, Emre S, Fischbach M, Harambat J et al (2015) Pathogens causing urinary tract infections in infants: a European overview by the ESCAPE study group. Eur J Pediatr 174:783\u2013790","journal-title":"Eur J Pediatr"},{"key":"3810_CR19","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s00467-011-1951-5","volume":"27","author":"N Marcus","year":"2012","unstructured":"Marcus N, Ashkenazi S, Samra Z, Cohen A, Livni G (2012) Community-acquired enterococcal urinary tract infections in hospitalized children. Pediatr Nephrol 27:109\u2013114","journal-title":"Pediatr Nephrol"},{"key":"3810_CR20","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1097\/01.ju.0000149826.70405.c5","volume":"173","author":"LJ Giorgi","year":"2005","unstructured":"Giorgi LJ, Bratislavsky G, Kogan BA (2005) Febrile urinary tract infections in infants: renal ultrasound remains necessary. J Urol 173:568\u2013570","journal-title":"J Urol"},{"key":"3810_CR21","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1007\/s00431-006-0113-4","volume":"165","author":"T Jahnukainen","year":"2006","unstructured":"Jahnukainen T, Honkinen O, Ruuskanen O, Mertsola J (2006) Ultrasonography after the first febrile urinary tract infection in children. Eur J Pediatr 165:556\u2013559","journal-title":"Eur J Pediatr"},{"key":"3810_CR22","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1007\/s00467-007-0556-5","volume":"22","author":"JB Lopez Sastre","year":"2007","unstructured":"Lopez Sastre JB, Ramos Aparicio A, Coto Cotallo GD, Fernandez Colomer B, Crespo Hernandez M (2007) Urinary tract infection in the newborn: clinical and ration imaging studies. Pediatr Nephrol 22:1735\u20131741","journal-title":"Pediatr Nephrol"},{"key":"3810_CR23","doi-asserted-by":"publisher","first-page":"e239","DOI":"10.1542\/peds.2008-1003","volume":"1213","author":"G Montini","year":"2009","unstructured":"Montini G, Zuchetta P, Tomasi L, Talenti E, Rigamonti W, Picco G et al (2009) Value of imaging studies after a first febrile urinary tract infection in young children: data from Italian renal infection study 1. Pediatrics 1213:e239\u2013e246","journal-title":"Pediatrics"},{"key":"3810_CR24","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1038\/jp.2009.147","volume":"30","author":"L Nowell","year":"2010","unstructured":"Nowell L, Moran C, Smith PB, Seed P, Alexander BD, Cotton M et al (2010) Prevalence of renal anomalies following urinary tract infections in hospitalized infant less than two months of age. J Perinatol 30:281\u2013285","journal-title":"J Perinatol"},{"key":"3810_CR25","doi-asserted-by":"publisher","first-page":"e665","DOI":"10.1542\/peds.2012-0164","volume":"131","author":"C Lascola","year":"2013","unstructured":"Lascola C, De Mutils C, Hewitt IK, Puccio G, Toffolo A, Zuccheta P et al (2013) Different guidelines for imaging after first UTI in febrile infants: yield, cost and radiation. Pediatrics 131:e665\u2013e671","journal-title":"Pediatrics"},{"key":"3810_CR26","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1016\/j.juro.2013.01.049","volume":"190","author":"TM Juliano","year":"2013","unstructured":"Juliano TM, Stephany HA, Clayton DB, Thomas JC, Pope JC 4th, Adams MC et al (2013) Incidence of abnormal imaging and recurrent pyelonephritis after first febrile urinary tract infection in children 2 to 24 months old. J Urol 190:1505\u20131510. https:\/\/doi.org\/10.1016\/j.juro.2013.01.049","journal-title":"J Urol"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-019-03810-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10096-019-03810-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-019-03810-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T23:32:41Z","timestamp":1665444761000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10096-019-03810-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,13]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["3810"],"URL":"https:\/\/doi.org\/10.1007\/s10096-019-03810-w","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,13]]},"assertion":[{"value":"1 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The research protocol was approved by the Ethics Committee of the Soroka University Medical Center.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Retrospective research, informed consent not needed.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}