{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:14:35Z","timestamp":1792782875831,"version":"4.5.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"BEIJING NATURAL SCIENCEFOUNDATION","award":["7192028"],"award-info":[{"award-number":["7192028"]}]},{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science & Technology Commission","doi-asserted-by":"crossref","award":["Z191100006619049"],"award-info":[{"award-number":["Z191100006619049"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s10096-021-04336-w","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T06:02:57Z","timestamp":1629093777000},"page":"9-20","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Clinical characteristics of 967 children with pertussis: a single-center analysis over an 8-year period in Beijing, China"],"prefix":"10.1007","volume":"41","author":[{"given":"Limin","family":"Kang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodai","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenpeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiegeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huixue","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Mi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,16]]},"reference":[{"issue":"3","key":"4336_CR1","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/j.pop.2018.05.003","volume":"45","author":"VTN Nguyen","year":"2018","unstructured":"Nguyen VTN, Simon L (2018) Pertussis: the whooping cough. Prim Care 45(3):423\u2013431. https:\/\/doi.org\/10.1016\/j.pop.2018.05.003","journal-title":"Prim Care"},{"key":"4336_CR2","doi-asserted-by":"publisher","first-page":"e26","DOI":"10.1017\/s0950268820000102","volume":"148","author":"TC Liu","year":"2020","unstructured":"Liu TC, Zhang J, Liu SQ, Yin AT, Ruan SM (2020) Evaluation of immunisation strategies for pertussis vaccines in Jinan, China - an interrupted time-series study. Epidemiol Infect 148:e26. https:\/\/doi.org\/10.1017\/s0950268820000102","journal-title":"Epidemiol Infect"},{"issue":"4","key":"4336_CR3","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1097\/inf.0000000000001761","volume":"37","author":"K Winter","year":"2018","unstructured":"Winter K, Zipprich J, Harriman K (2018) Pertussis in California: a tale of 2 epidemics. Pediatr Infect Dis J 37(4):324\u2013328. https:\/\/doi.org\/10.1097\/inf.0000000000001761","journal-title":"Pediatr Infect Dis J"},{"issue":"8","key":"4336_CR4","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1097\/pcc.0000000000000851","volume":"17","author":"L Straney","year":"2016","unstructured":"Straney L, Schibler A, Ganeshalingham A, Alexander J, Festa M, Slater A et al (2016) Burden and outcomes of severe pertussis infection in critically ill infants. Pediatr Crit Care Med: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 17(8):735\u2013742. https:\/\/doi.org\/10.1097\/pcc.0000000000000851","journal-title":"Pediatr Crit Care Med: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies"},{"issue":"2","key":"4336_CR5","first-page":"211","volume":"66","author":"I Paradowska-Stankiewicz","year":"2012","unstructured":"Paradowska-Stankiewicz I, Rudowska J (2012) Pertussis in Poland in 2010. Przegl Epidemiol 66(2):211\u2013214","journal-title":"Przegl Epidemiol"},{"issue":"2","key":"4336_CR6","first-page":"199","volume":"67","author":"I Paradowska-Stankiewicz","year":"2013","unstructured":"Paradowska-Stankiewicz I, Rudowska J (2013) Pertussis in Poland in 2011. Przegl Epidemiol 67(2):199\u2013201 (319-121)","journal-title":"Przegl Epidemiol"},{"issue":"2","key":"4336_CR7","first-page":"205","volume":"68","author":"I Paradowska-Stankiewicz","year":"2014","unstructured":"Paradowska-Stankiewicz I, Rudowska J (2014) Pertussis in Poland in 2012. Przegl Epidemiol 68(2):205\u2013207 (325-207)","journal-title":"Przegl Epidemiol"},{"issue":"9","key":"4336_CR8","doi-asserted-by":"publisher","first-page":"858","DOI":"10.3760\/cma.j.issn.0253-9624.2017.09.017","volume":"51","author":"TC Liu","year":"2017","unstructured":"Liu TC, Song KJ, Zhang XH, Liu XX, Li CB, Zhang J (2017) Epidemiological analysis of pertussis in Jinan, 2005\u20132015. Zhonghua Yu Fang Yi Xue Za Zhi [Chinese journal of preventive medicine] 51(9):858\u2013860. https:\/\/doi.org\/10.3760\/cma.j.issn.0253-9624.2017.09.017","journal-title":"Zhonghua Yu Fang Yi Xue Za Zhi [Chinese journal of preventive medicine]"},{"issue":"7","key":"4336_CR9","doi-asserted-by":"publisher","first-page":"545","DOI":"10.3967\/bes2017.073","volume":"30","author":"HT Huang","year":"2017","unstructured":"Huang HT, Gao ZG, Liu Y, Wang LJ, Liu YP, Zhang Y (2017) Epidemiological characteristics and risk factors of the pertussis in infants < 12 months of age in Tianjin, China. Biomed Environ Sci: BES 30(7):545\u2013548. https:\/\/doi.org\/10.3967\/bes2017.073","journal-title":"Biomed Environ Sci: BES"},{"issue":"5","key":"4336_CR10","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1080\/21645515.2016.1276139","volume":"13","author":"P Stefanelli","year":"2017","unstructured":"Stefanelli P, Buttinelli G, Vacca P, Tozzi AE, Midulla F, Carsetti R et al (2017) Severe pertussis infection in infants less than 6 months of age: clinical manifestations and molecular characterization. Hum Vaccin Immunother 13(5):1073\u20131077. https:\/\/doi.org\/10.1080\/21645515.2016.1276139","journal-title":"Hum Vaccin Immunother"},{"key":"4336_CR11","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.jpeds.2017.05.032","volume":"188","author":"A Aquino-Andrade","year":"2017","unstructured":"Aquino-Andrade A, Mart\u00ednez-Leyva G, M\u00e9rida-Vieyra J, Saltigeral P, Lara A, Dom\u00ednguez W et al (2017) Real-time polymerase chain reaction-based detection of Bordetella pertussis in Mexican infants and their contacts: a 3-year multicenter study. J Pediatr 188:217-223.e211. https:\/\/doi.org\/10.1016\/j.jpeds.2017.05.032","journal-title":"J Pediatr"},{"key":"4336_CR12","unstructured":"Case definitions for infectious conditions under public health surveillance (1997) Centers for Disease Control and Prevention. MMWR Recomm Rep 46(RR-10):1\u201355"},{"key":"4336_CR13","doi-asserted-by":"publisher","unstructured":"WHO Publication (2011) Pertussis vaccines: WHO position paper--recommendations. Vaccine 29(13):2355\u20132356. https:\/\/doi.org\/10.1016\/j.vaccine.2010.11.059","DOI":"10.1016\/j.vaccine.2010.11.059"},{"issue":"3","key":"4336_CR14","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1086\/589753","volume":"47","author":"CD Paddock","year":"2008","unstructured":"Paddock CD, Sanden GN, Cherry JD, Gal AA, Langston C, Tatti KM et al (2008) Pathology and pathogenesis of fatal Bordetella pertussis infection in infants. Clin Infect Dis: an official publication of the Infectious Diseases Society of America 47(3):328\u2013338. https:\/\/doi.org\/10.1086\/589753","journal-title":"Clin Infect Dis: an official publication of the Infectious Diseases Society of America"},{"key":"4336_CR15","doi-asserted-by":"publisher","unstructured":"Chang IF, Lee PI, Lu CY, Chen JM, Huang LM, Chang LY (2019) Resurgence of pertussis in Taiwan during 2009\u20132015 and its impact on infants. J Microbiology Immunol Infect =Wei mian yu gan ran za zhi 52(4):542\u2013548. https:\/\/doi.org\/10.1016\/j.jmii.2019.06.002","DOI":"10.1016\/j.jmii.2019.06.002"},{"key":"4336_CR16","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1186\/1471-2458-11-694","volume":"11","author":"DN Fisman","year":"2011","unstructured":"Fisman DN, Tang P, Hauck T, Richardson S, Drews SJ, Low DE et al (2011) Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling. BMC Public Health 11:694. https:\/\/doi.org\/10.1186\/1471-2458-11-694","journal-title":"BMC Public Health"},{"issue":"Pt 8","key":"4336_CR17","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1099\/jmm.0.009878-0","volume":"58","author":"NK Fry","year":"2009","unstructured":"Fry NK, Duncan J, Wagner K, Tzivra O, Doshi N, Litt DJ et al (2009) Role of PCR in the diagnosis of pertussis infection in infants: 5 years\u2019 experience of provision of a same-day real-time PCR service in England and Wales from 2002 to 2007. J Med Microbiol 58(Pt 8):1023\u20131029. https:\/\/doi.org\/10.1099\/jmm.0.009878-0","journal-title":"J Med Microbiol"},{"key":"4336_CR18","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.ijid.2019.05.014","volume":"84","author":"Z Liu","year":"2019","unstructured":"Liu Z, Liu S, Shu Y, Yang Z, Peng B, Xu H et al (2019) Severe Bordetella pertussis infection and vaccine issue in Chongqing, from 2012 to 2018. Int J Infect Dis: IJID: official publication of the International Society for Infectious Diseases 84:102\u2013108. https:\/\/doi.org\/10.1016\/j.ijid.2019.05.014","journal-title":"Int J Infect Dis: IJID: official publication of the International Society for Infectious Diseases"},{"key":"4336_CR19","doi-asserted-by":"publisher","unstructured":"Domenech de Cell\u00e8s M, Magpantay FM, King AA, Rohani P (2016) The pertussis enigma: reconciling epidemiology, immunology and evolution. Proc Biol Sci 283(1822):20152309. https:\/\/doi.org\/10.1098\/rspb.2015.2309","DOI":"10.1098\/rspb.2015.2309"},{"issue":"3\u20134","key":"4336_CR20","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.epidem.2011.10.001","volume":"3","author":"P Rohani","year":"2011","unstructured":"Rohani P, Drake JM (2011) The decline and resurgence of pertussis in the US. Epidemics 3(3\u20134):183\u2013188. https:\/\/doi.org\/10.1016\/j.epidem.2011.10.001","journal-title":"Epidemics"},{"issue":"8","key":"4336_CR21","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1080\/23744235.2018.1457796","volume":"50","author":"SM Oliveira","year":"2018","unstructured":"Oliveira SM, Gon\u00e7alves-Pinho M, Freitas A, Guimar\u00e3es H, Azevedo I (2018) Trends and costs of pertussis hospitalizations in Portugal, 2000 to 2015: from 0 to 95 years old. Infect Dis 50(8):625\u2013633. https:\/\/doi.org\/10.1080\/23744235.2018.1457796","journal-title":"Infect Dis"},{"issue":"suppl 4","key":"4336_CR22","doi-asserted-by":"publisher","first-page":"S154","DOI":"10.1093\/cid\/ciw526","volume":"63","author":"CJ Gill","year":"2016","unstructured":"Gill CJ, Mwananyanda L, MacLeod W, Kwenda G, Mwale M, Williams AL et al (2016) Incidence of Severe and nonsevere pertussis among HIV-exposed and -unexposed Zambian infants through 14 weeks of age: results from the Southern Africa Mother Infant Pertussis Study (SAMIPS), a longitudinal birth cohort study. Clin Infect Dis: an official publication of the Infectious Diseases Society of America 63(suppl 4):S154-s164. https:\/\/doi.org\/10.1093\/cid\/ciw526","journal-title":"Clin Infect Dis: an official publication of the Infectious Diseases Society of America"},{"issue":"4","key":"4336_CR23","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1097\/PCC.0b013e31828a70fe","volume":"14","author":"JT Berger","year":"2013","unstructured":"Berger JT, Carcillo JA, Shanley TP, Wessel DL, Clark A, Holubkov R et al (2013) Critical pertussis illness in children: a multicenter prospective cohort study. Pediatr Crit Care Med: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 14(4):356\u2013365. https:\/\/doi.org\/10.1097\/PCC.0b013e31828a70fe","journal-title":"Pediatr Crit Care Med: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies"},{"issue":"7","key":"4336_CR24","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1093\/cid\/civ472","volume":"61","author":"K Winter","year":"2015","unstructured":"Winter K, Zipprich J, Harriman K, Murray EL, Gornbein J, Hammer SJ et al (2015) Risk factors associated with infant deaths from pertussis: a case-control study. Clin Infect Dis: an official publication of the Infectious Diseases Society of America 61(7):1099\u20131106. https:\/\/doi.org\/10.1093\/cid\/civ472","journal-title":"Clin Infect Dis: an official publication of the Infectious Diseases Society of America"},{"issue":"4","key":"4336_CR25","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1038\/nrmicro3235","volume":"12","author":"JA Melvin","year":"2014","unstructured":"Melvin JA, Scheller EV, Miller JF, Cotter PA (2014) Bordetella pertussis pathogenesis: current and future challenges. Nat Rev Microbiol 12(4):274\u2013288. https:\/\/doi.org\/10.1038\/nrmicro3235","journal-title":"Nat Rev Microbiol"},{"issue":"4","key":"4336_CR26","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1128\/cmr.00031-15","volume":"28","author":"A van der Zee","year":"2015","unstructured":"van der Zee A, Schellekens JF, Mooi FR (2015) Laboratory diagnosis of pertussis. Clin Microbiol Rev 28(4):1005\u20131026. https:\/\/doi.org\/10.1128\/cmr.00031-15","journal-title":"Clin Microbiol Rev"},{"issue":"3","key":"4336_CR27","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.pupt.2010.10.011","volume":"24","author":"K Wang","year":"2011","unstructured":"Wang K, Harnden A (2011) Pertussis-induced cough. Pulm Pharmacol Ther 24(3):304\u2013307. https:\/\/doi.org\/10.1016\/j.pupt.2010.10.011","journal-title":"Pulm Pharmacol Ther"},{"issue":"Pt 6","key":"4336_CR28","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1099\/jmm.0.030049-0","volume":"60","author":"JA Grogan","year":"2011","unstructured":"Grogan JA, Logan C, O\u2019Leary J, Rush R, O\u2019Sullivan N (2011) Real-time PCR-based detection of Bordetella pertussis and Bordetella parapertussis in an Irish paediatric population. J Med Microbiol 60(Pt 6):722\u2013729. https:\/\/doi.org\/10.1099\/jmm.0.030049-0","journal-title":"J Med Microbiol"},{"issue":"12","key":"4336_CR29","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1093\/cid\/cis302","volume":"54","author":"JD Cherry","year":"2012","unstructured":"Cherry JD, Tan T, Wirsing von K\u00f6nig CH, Forsyth KD, Thisyakorn U, Greenberg D et al (2012) Clinical definitions of pertussis: summary of a Global Pertussis Initiative roundtable meeting, February 2011. Clin Infect Dis: an official publication of the Infectious Diseases Society of America 54(12):1756\u20131764. https:\/\/doi.org\/10.1093\/cid\/cis302","journal-title":"Clin Infect Dis: an official publication of the Infectious Diseases Society of America"},{"issue":"35","key":"4336_CR30","doi-asserted-by":"publisher","first-page":"5179","DOI":"10.1016\/j.vaccine.2012.06.005","volume":"30","author":"A Bechini","year":"2012","unstructured":"Bechini A, Tiscione E, Boccalini S, Levi M, Bonanni P (2012) Acellular pertussis vaccine use in risk groups (adolescents, pregnant women, newborns and health care workers): a review of evidences and recommendations. Vaccine 30(35):5179\u20135190. https:\/\/doi.org\/10.1016\/j.vaccine.2012.06.005","journal-title":"Vaccine"},{"issue":"3","key":"4336_CR31","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1128\/cmr.00083-15","volume":"29","author":"PE Kilgore","year":"2016","unstructured":"Kilgore PE, Salim AM, Zervos MJ, Schmitt HJ (2016) Pertussis: microbiology, disease, treatment, and prevention. Clin Microbiol Rev 29(3):449\u2013486. https:\/\/doi.org\/10.1128\/cmr.00083-15","journal-title":"Clin Microbiol Rev"},{"issue":"2","key":"4336_CR32","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s15010-016-0943-6","volume":"45","author":"G Fedele","year":"2017","unstructured":"Fedele G, Carollo M, Palazzo R, Stefanelli P, Pandolfi E, Gesualdo F et al (2017) Parents as source of pertussis transmission in hospitalized young infants. Infection 45(2):171\u2013178. https:\/\/doi.org\/10.1007\/s15010-016-0943-6","journal-title":"Infection"},{"issue":"4","key":"4336_CR33","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1542\/peds.2015-1120","volume":"136","author":"TH Skoff","year":"2015","unstructured":"Skoff TH, Kenyon C, Cocoros N, Liko J, Miller L, Kudish K et al (2015) Sources of infant pertussis infection in the United States. Pediatrics 136(4):635\u2013641. https:\/\/doi.org\/10.1542\/peds.2015-1120","journal-title":"Pediatrics"},{"issue":"3","key":"4336_CR34","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1093\/cid\/ciu821","volume":"60","author":"G Dabrera","year":"2015","unstructured":"Dabrera G, Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E et al (2015) A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales, 2012\u20132013. Clin Infect Dis: an official publication of the Infectious Diseases Society of America 60(3):333\u2013337. https:\/\/doi.org\/10.1093\/cid\/ciu821","journal-title":"Clin Infect Dis: an official publication of the Infectious Diseases Society of America"},{"issue":"3","key":"4336_CR35","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1093\/cid\/ciu823","volume":"60","author":"JD Cherry","year":"2015","unstructured":"Cherry JD (2015) Tetanus-diphtheria-pertussis immunization in pregnant women and the prevention of pertussis in young infants. Clin Infect Dis: an official publication of the Infectious Diseases Society of America 60(3):338\u2013340. https:\/\/doi.org\/10.1093\/cid\/ciu823","journal-title":"Clin Infect Dis: an official publication of the Infectious Diseases Society of America"},{"issue":"7","key":"4336_CR36","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1093\/infdis\/jiu001","volume":"209","author":"TA Clark","year":"2014","unstructured":"Clark TA (2014) Changing pertussis epidemiology: everything old is new again. J Infect Dis 209(7):978\u2013981. https:\/\/doi.org\/10.1093\/infdis\/jiu001","journal-title":"J Infect Dis"},{"issue":"1","key":"4336_CR37","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1186\/s12887-019-1615-3","volume":"19","author":"DX Wu","year":"2019","unstructured":"Wu DX, Chen Q, Yao KH, Li L, Shi W, Ke JW et al (2019) Pertussis detection in children with cough of any duration. BMC Pediatr 19(1):236. https:\/\/doi.org\/10.1186\/s12887-019-1615-3","journal-title":"BMC Pediatr"},{"issue":"2","key":"4336_CR38","doi-asserted-by":"publisher","first-page":"e285","DOI":"10.1542\/peds.2004-2759","volume":"116","author":"KM Bisgard","year":"2005","unstructured":"Bisgard KM, Rhodes P, Connelly BL, Bi D, Hahn C, Patrick S et al (2005) Pertussis vaccine effectiveness among children 6 to 59 months of age in the United States, 1998\u20132001. Pediatrics 116(2):e285-294. https:\/\/doi.org\/10.1542\/peds.2004-2759","journal-title":"Pediatrics"},{"issue":"12","key":"4336_CR39","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1016\/j.vaccine.2015.10.136","volume":"34","author":"WHO","year":"2016","unstructured":"WHO (2016) Pertussis vaccines: WHO position paper, August 2015\u2013Recommendations. Vaccine 34(12):1423\u20131425. https:\/\/doi.org\/10.1016\/j.vaccine.2015.10.136","journal-title":"Vaccine"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-021-04336-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-021-04336-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-021-04336-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T09:21:48Z","timestamp":1641374508000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-021-04336-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,16]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["4336"],"URL":"https:\/\/doi.org\/10.1007\/s10096-021-04336-w","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,16]]},"assertion":[{"value":"30 April 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Ethics Committee of Affiliated Children\u2019s Hospital, Capital Institute of Pediatrics (SHERLL2021031).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"This study has not been submitted for publication or consideration in any other journal.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}