{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T17:31:54Z","timestamp":1776274314050,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1007\/s10096-022-04429-0","type":"journal-article","created":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T13:03:19Z","timestamp":1647608599000},"page":"761-769","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A meta-analysis for the role of aminoglycosides and tigecyclines in combined regimens against colistin- and carbapenem-resistant Klebsiella pneumoniae bloodstream infections"],"prefix":"10.1007","volume":"41","author":[{"given":"Yusuf Mert","family":"Demirlenk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lal Sude","family":"G\u00fccer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duygu","family":"U\u00e7ku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cem","family":"Tanr\u0131\u00f6ver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merve","family":"Akyol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeynepg\u00fcl","family":"Kalay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin\u00e7","family":"Bar\u00e7\u0131n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fc\u015ft\u00fc Emre","family":"Akcan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00fcsun","family":"Can","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"G\u00f6nen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6nder","family":"Erg\u00f6n\u00fcl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,3,18]]},"reference":[{"issue":"4","key":"4429_CR1","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1128\/CMR.14.4.933-951.2001","volume":"14","author":"PA Bradford","year":"2001","unstructured":"Bradford PA (2001) Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev 14(4):933\u2013951, table of contents","journal-title":"Clin Microbiol Rev"},{"issue":"6","key":"4429_CR2","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/j.cmi.2016.01.023","volume":"22","author":"C Hauck","year":"2016","unstructured":"Hauck C, Cober E, Richter SS, Perez F, Salata RA, Kalayjian RC, Watkins RR, Scalera NM, Doi Y, Kaye KS, Evans S, Fowler VG Jr, Bonomo RA, van Duin D, Antibacterial resistance leadership G (2016) Spectrum of excess mortality due to carbapenem-resistant Klebsiella pneumoniae infections. Clin Microbiol Infect 22(6):513\u2013519","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"4429_CR3","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.jhin.2017.11.014","volume":"98","author":"M Aydin","year":"2018","unstructured":"Aydin M, Ergonul O, Azap A, Bilgin H, Aydin G, Cavus SA, Demiroglu YZ, Aliskan HE, Memikoglu O, Menekse S, Kaya S, Demir NA, Karaoglan I, Basaran S, Hatipoglu C, Erdinc S, Yilmaz E, Tumturk A, Tezer Y, Demirkaya H, Cakar SE, Keske S, Tekin S, Yardimci C, Karakoc C, Ergen P, Azap O, Mulazimoglu L, Ural O, Can F, Akalin H, Turkish Society of Clinical M, Infectious Diseases H-rISGT (2018) Rapid emergence of colistin resistance and its impact on fatality among healthcare-associated infections. J Hosp Infect 98(3):260\u2013263","journal-title":"J Hosp Infect"},{"issue":"4","key":"4429_CR4","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.jhin.2016.08.012","volume":"94","author":"O Ergonul","year":"2016","unstructured":"Ergonul O, Aydin M, Azap A, Basaran S, Tekin S, Kaya S, Gulsun S, Yoruk G, Kursun E, Yesilkaya A, Simsek F, Yilmaz E, Bilgin H, Hatipoglu C, Cabadak H, Tezer Y, Togan T, Karaoglan I, Inan A, Engin A, Aliskan HE, Yavuz SS, Erdinc S, Mulazimoglu L, Azap O, Can F, Akalin H, Timurkaynak F, Turkish Society of Clinical M, Infectious Diseases H-RISG (2016) Healthcare-associated Gram-negative bloodstream infections: antibiotic resistance and predictors of mortality. J Hosp Infect 94(4):381\u2013385","journal-title":"J Hosp Infect"},{"issue":"4","key":"4429_CR5","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1093\/jac\/dkl562","volume":"59","author":"A Antoniadou","year":"2007","unstructured":"Antoniadou A, Kontopidou F, Poulakou G, Koratzanis E, Galani I, Papadomichelakis E, Kopterides P, Souli M, Armaganidis A, Giamarellou H (2007) Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster. J Antimicrob Chemother 59(4):786\u2013790","journal-title":"J Antimicrob Chemother"},{"issue":"12","key":"4429_CR6","doi-asserted-by":"publisher","first-page":"1798","DOI":"10.1111\/j.1469-0691.2011.03514.x","volume":"17","author":"O Zarkotou","year":"2011","unstructured":"Zarkotou O, Pournaras S, Tselioti P, Dragoumanos V, Pitiriga V, Ranellou K, Prekates A, Themeli-Digalaki K, Tsakris A (2011) Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment. Clin Microbiol Infect 17(12):1798\u20131803","journal-title":"Clin Microbiol Infect"},{"key":"4429_CR7","doi-asserted-by":"crossref","unstructured":"Guducuoglu H, Gursoy NC, Yakupogullari Y, Parlak M, Karasin G, Sunnetcioglu M, Otlu B (2017) Hospital outbreak of a colistin-resistant, NDM-1- and OXA-48-producing Klebsiella pneumoniae: High mortality from pandrug resistance. Microb Drug Resist 24(7):966\u2013972","DOI":"10.1089\/mdr.2017.0173"},{"issue":"6","key":"4429_CR8","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.ijantimicag.2007.07.024","volume":"30","author":"Z Samra","year":"2007","unstructured":"Samra Z, Ofir O, Lishtzinsky Y, Madar-Shapiro L, Bishara J (2007) Outbreak of carbapenem-resistant Klebsiella pneumoniae producing KPC-3 in a tertiary medical centre in Israel. Int J Antimicrob Agents 30(6):525\u2013529","journal-title":"Int J Antimicrob Agents"},{"issue":"1","key":"4429_CR9","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1128\/AAC.00762-09","volume":"54","author":"JY Suh","year":"2010","unstructured":"Suh JY, Son JS, Chung DR, Peck KR, Ko KS, Song JH (2010) Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. Antimicrob Agents Chemother 54(1):560\u2013562","journal-title":"Antimicrob Agents Chemother"},{"issue":"11","key":"4429_CR10","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1016\/j.ajic.2017.06.028","volume":"45","author":"A Kaur","year":"2017","unstructured":"Kaur A, Gandra S, Gupta P, Mehta Y, Laxminarayan R, Sengupta S (2017) Clinical outcome of dual colistin- and carbapenem-resistant Klebsiella pneumoniae bloodstream infections: a single-center retrospective study of 75 cases in India. Am J Infect Control 45(11):1289\u20131291","journal-title":"Am J Infect Control"},{"issue":"5","key":"4429_CR11","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1093\/jac\/dkx532","volume":"73","author":"F Can","year":"2018","unstructured":"Can F, Menekse S, Ispir P, Atac N, Albayrak O, Demir T, Karaaslan DC, Karahan SN, Kapmaz M, Kurt Azap O, Timurkaynak F, Simsek Yavuz S, Basaran S, Yoruk F, Azap A, Koculu S, Benzonana N, Lack NA, Gonen M, Ergonul O (2018) Impact of the ST101 clone on fatality among patients with colistin-resistant Klebsiella pneumoniae infection. J Antimicrob Chemother 73(5):1235\u20131241","journal-title":"J Antimicrob Chemother"},{"issue":"4","key":"4429_CR12","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/S1473-3099(18)30099-9","volume":"18","author":"M Paul","year":"2018","unstructured":"Paul M, Daikos GL, Durante-Mangoni E, Yahav D, Carmeli Y, Benattar YD, Skiada A, Andini R, Eliakim-Raz N, Nutman A, Zusman O, Antoniadou A, Pafundi PC, Adler A, Dickstein Y, Pavleas I, Zampino R, Daitch V, Bitterman R, Zayyad H, Koppel F, Levi I, Babich T, Friberg LE, Mouton JW, Theuretzbacher U, Leibovici L (2018) Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial. Lancet Infect Dis 18(4):391\u2013400","journal-title":"Lancet Infect Dis"},{"issue":"11","key":"4429_CR13","doi-asserted-by":"publisher","first-page":"E9","DOI":"10.1111\/j.1469-0691.2011.03649.x","volume":"17","author":"F Kontopidou","year":"2011","unstructured":"Kontopidou F, Plachouras D, Papadomichelakis E, Koukos G, Galani I, Poulakou G, Dimopoulos G, Antoniadou A, Armaganidis A, Giamarellou H (2011) Colonization and infection by colistin-resistant Gram-negative bacteria in a cohort of critically ill patients. Clin Microbiol Infect 17(11):E9\u2013E11","journal-title":"Clin Microbiol Infect"},{"issue":"2","key":"4429_CR14","doi-asserted-by":"publisher","first-page":"103","DOI":"10.4103\/ijccm.IJCCM_430_17","volume":"22","author":"R Aggarwal","year":"2018","unstructured":"Aggarwal R, Rastogi N, Mathur P, Soni KD, Kumar S, Gupta A, Sagar S (2018) Colistin-resistant Klebsiella pneumoniae in surgical polytrauma intensive care unit of level-1 trauma center: first case series from trauma patients in India. Indian J Crit Care Med 22(2):103\u2013106","journal-title":"Indian J Crit Care Med"},{"key":"4429_CR15","doi-asserted-by":"crossref","unstructured":"Paul M, Carrara E, Retamar P, Tangden T, Bitterman R, Bonomo RA, de Waele J, Daikos GL, Akova M, Harbarth S, Pulcini C, Garnacho-Montero J, Seme K, Tumbarello M, Lindemann PC, Gandra S, Yu Y, Bassetti M, Mouton JW, Tacconelli E, Rodriguez-Bano J (2021) European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine). Clin Microbiol Infect (in press)","DOI":"10.1016\/j.cmi.2021.11.025"},{"key":"4429_CR16","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hrobjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71","journal-title":"BMJ"},{"key":"4429_CR17","doi-asserted-by":"publisher","first-page":"i4919","DOI":"10.1136\/bmj.i4919","volume":"355","author":"JA Sterne","year":"2016","unstructured":"Sterne JA, Hernan MA, Reeves BC, Savovic J, Berkman ND, Viswanathan M, Henry D, Altman DG, Ansari MT, Boutron I, Carpenter JR, Chan AW, Churchill R, Deeks JJ, Hrobjartsson A, Kirkham J, Juni P, Loke YK, Pigott TD, Ramsay CR, Regidor D, Rothstein HR, Sandhu L, Santaguida PL, Schunemann HJ, Shea B, Shrier I, Tugwell P, Turner L, Valentine JC, Waddington H, Waters E, Wells GA, Whiting PF, Higgins JP (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919","journal-title":"BMJ"},{"issue":"5","key":"4429_CR18","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1089\/mdr.2015.0282","volume":"22","author":"A Mavroidi","year":"2016","unstructured":"Mavroidi A, Katsiari M, Likousi S, Palla E, Roussou Z, Nikolaou C, Maguina A, Platsouka ED (2016) Characterization of ST258 Colistin-Resistant, blaKPC-Producing Klebsiella pneumoniae in a Greek Hospital. Microb Drug Resist 22(5):392\u2013398","journal-title":"Microb Drug Resist"},{"issue":"1","key":"4429_CR19","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.ijantimicag.2013.09.010","volume":"43","author":"K Pontikis","year":"2014","unstructured":"Pontikis K, Karaiskos I, Bastani S, Dimopoulos G, Kalogirou M, Katsiari M, Oikonomou A, Poulakou G, Roilides E, Giamarellou H (2014) Outcomes of critically ill intensive care unit patients treated with fosfomycin for infections due to pandrug-resistant and extensively drug-resistant carbapenemase-producing Gram-negative bacteria. Int J Antimicrob Agents 43(1):52\u201359","journal-title":"Int J Antimicrob Agents"},{"issue":"6","key":"4429_CR20","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1086\/528719","volume":"46","author":"M Souli","year":"2008","unstructured":"Souli M, Kontopidou FV, Papadomichelakis E, Galani I, Armaganidis A, Giamarellou H (2008) Clinical experience of serious infections caused by Enterobacteriaceae producing VIM-1 metallo-beta-lactamase in a Greek University Hospital. Clin Infect Dis 46(6):847\u2013854","journal-title":"Clin Infect Dis"},{"issue":"8","key":"4429_CR21","doi-asserted-by":"publisher","first-page":"e00406","DOI":"10.1128\/AAC.00406-17","volume":"61","author":"I Machuca","year":"2017","unstructured":"Machuca I, Gutierrez-Gutierrez B, Gracia-Ahufinger I, Rivera Espinar F, Cano A, Guzman-Puche J, Perez-Nadales E, Natera C, Rodriguez M, Leon R, Caston JJ, Rodriguez-Lopez F, Rodriguez-Bano J, Torre-Cisneros J (2017) Mortality associated with bacteremia due to colistin-resistant Klebsiella pneumoniae with high-level meropenem resistance: importance of combination therapy without colistin and carbapenems. Antimicrob Agents Chemother 61(8):e00406\u201317","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"4429_CR22","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.ijantimicag.2013.12.002","volume":"43","author":"FF Tuon","year":"2014","unstructured":"Tuon FF, Rigatto MH, Lopes CK, Kamei LK, Rocha JL, Zavascki AP (2014) Risk factors for acute kidney injury in patients treated with polymyxin B or colistin methanesulfonate sodium. Int J Antimicrob Agents 43(4):349\u2013352","journal-title":"Int J Antimicrob Agents"},{"key":"4429_CR23","doi-asserted-by":"publisher","first-page":"e29","DOI":"10.1590\/s1678-9946201961029","volume":"61","author":"I Boszczowski","year":"2019","unstructured":"Boszczowski I, Salomao MC, Moura ML, Freire MP, Guimaraes T, Cury AP, Rossi F, Rizek CF, Martins RCR, Costa SF (2019) Multidrug-resistant Klebsiella pneumoniae: genetic diversity, mechanisms of resistance to polymyxins and clinical outcomes in a tertiary teaching hospital in Brazil. Rev Inst Med Trop Sao Paulo 61:e29","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"4429_CR24","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.ijid.2019.06.008","volume":"86","author":"S Menekse","year":"2019","unstructured":"Menekse S, Cag Y, Isik ME, Sahin S, Haciseyitoglu D, Can F, Ergonul O (2019) The effect of colistin resistance and other predictors on fatality among patients with bloodstream infections due to Klebsiella pneumoniae in an OXA-48 dominant region. Int J Infect Dis 86:208\u2013211","journal-title":"Int J Infect Dis"},{"issue":"4","key":"4429_CR25","doi-asserted-by":"publisher","first-page":"2322","DOI":"10.1128\/AAC.02166-13","volume":"58","author":"GL Daikos","year":"2014","unstructured":"Daikos GL, Tsaousi S, Tzouvelekis LS, Anyfantis I, Psichogiou M, Argyropoulou A, Stefanou I, Sypsa V, Miriagou V, Nepka M, Georgiadou S, Markogiannakis A, Goukos D, Skoutelis A (2014) Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems. Antimicrob Agents Chemother 58(4):2322\u20132328","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"4429_CR26","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/j.ijantimicag.2008.05.016","volume":"32","author":"ME Falagas","year":"2008","unstructured":"Falagas ME, Rafailidis PI, Matthaiou DK, Virtzili S, Nikita D, Michalopoulos A (2008) Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: characteristics and outcome in a series of 28 patients. Int J Antimicrob Agents 32(5):450\u2013454","journal-title":"Int J Antimicrob Agents"},{"issue":"3","key":"4429_CR27","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1093\/jac\/dku432","volume":"70","author":"M Gonzalez-Padilla","year":"2015","unstructured":"Gonzalez-Padilla M, Torre-Cisneros J, Rivera-Espinar F, Pontes-Moreno A, Lopez-Cerero L, Pascual A, Natera C, Rodriguez M, Salcedo I, Rodriguez-Lopez F, Rivero A, Rodriguez-Bano J (2015) Gentamicin therapy for sepsis due to carbapenem-resistant and colistin-resistant Klebsiella pneumoniae. J Antimicrob Chemother 70(3):905\u2013913","journal-title":"J Antimicrob Chemother"},{"issue":"9","key":"4429_CR28","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1111\/j.1469-0691.2011.03572.x","volume":"17","author":"ML Mezzatesta","year":"2011","unstructured":"Mezzatesta ML, Gona F, Caio C, Petrolito V, Sciortino D, Sciacca A, Santangelo C, Stefani S (2011) Outbreak of KPC-3-producing, and colistin-resistant, Klebsiella pneumoniae infections in two Sicilian hospitals. Clin Microbiol Infect 17(9):1444\u20131447","journal-title":"Clin Microbiol Infect"},{"issue":"7","key":"4429_CR29","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1093\/cid\/ciab295","volume":"72","author":"PD Tamma","year":"2021","unstructured":"Tamma PD, Aitken SL, Bonomo RA, Mathers AJ, van Duin D, Clancy CJ (2021) Infectious Diseases Society of America guidance on the treatment of extended-spectrum beta-lactamase producing Enterobacterales (ESBL-E), carbapenem-resistant enterobacterales (CRE), and Pseudomonas aeruginosa with difficult-to-treat resistance (DTR-P. aeruginosa). Clin Infect Dis 72(7):1109\u20131116","journal-title":"Clin Infect Dis"},{"key":"4429_CR30","unstructured":"EUCAST (2022) Breakpoint tables for interpretation of MICs and zone diameters. The European Committee on Antimicrobial Susceptibility Testing, Version 12.0"},{"issue":"4","key":"4429_CR31","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1007\/s10096-019-03468-4","volume":"38","author":"MP Freire","year":"2019","unstructured":"Freire MP, de Oliveira GD, Cury AP, Francisco GR, Dos Santos NF, Spadao F, Bueno MFC, Camargo CH, de Paula FJ, Rossi F, Nahas WC, David-Neto E, Pierrotti LC (2019) The role of therapy with aminoglycoside in the outcomes of kidney transplant recipients infected with polymyxin- and carbapenem-resistant Enterobacteriaceae. Eur J Clin Microbiol Infect Dis 38(4):755\u2013765","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-022-04429-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-022-04429-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-022-04429-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T11:07:30Z","timestamp":1650625650000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-022-04429-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,18]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["4429"],"URL":"https:\/\/doi.org\/10.1007\/s10096-022-04429-0","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,18]]},"assertion":[{"value":"30 November 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All the data for analysis is available.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The codes of the software implementation (in\u00a0R) are available.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The analysis of systematic review is exempt from IRB review.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not Applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not Applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"No conflicts of interest or competing interests were declared.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}