{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T04:34:44Z","timestamp":1778646884170,"version":"3.51.4"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"abstract":"<jats:title>Abstract\n<\/jats:title><jats:p>Infections with hypervirulent <jats:italic>Klebsiella pneumoniae<\/jats:italic> (hvKp) commonly presents with primary liver infection, bacteremia, and metastatic abscesses. Here, we present 2 cases of severe community-acquired pulmonary infections by hvKp in patients in the Netherlands without recent travel history. Both bacterial isolates are closely related to an archetype ST23 hvKp reference isolate. Based on these findings, surveillance programs on hvKp may consider to include isolates from community-acquired pneumonia by <jats:italic>K. pneumoniae<\/jats:italic>.<\/jats:p>","DOI":"10.1007\/s10096-022-04470-z","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T17:17:06Z","timestamp":1657041426000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Brief report: community-acquired Friedlander\u2019s pneumonia and pulmonary metastatic Klebsiella pneumoniae infection caused by hypervirulent ST23 in the Netherlands"],"prefix":"10.1007","author":[{"given":"Monika","family":"Fliss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte H. S. B.","family":"van den Berg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed","family":"Kuijper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daan W.","family":"Notermans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoni P. A.","family":"Hendrickx","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirthe H.","family":"Schoots","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2319-8147","authenticated-orcid":false,"given":"Erik","family":"Bathoorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,7,5]]},"reference":[{"issue":"4","key":"4470_CR1","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1378\/chest.53.4.481","volume":"53","author":"NR Hoffman","year":"1968","unstructured":"Hoffman NR, Preston FS Jr (1968) Friedlander\u2019s pneumonia. A report of 11 cases and appraisal of antibiotic therapy. Dis Chest 53(4):481\u2013486","journal-title":"Dis Chest"},{"key":"4470_CR2","doi-asserted-by":"publisher","unstructured":"Russo TA, Marr CM (2019) Hypervirulent Klebsiella pneumoniae. Clin Microbiol Rev 32(3):e00001\u201319.\u00a0\u00a0https:\/\/doi.org\/10.1128\/CMR.00001-19. Print 2019 Jun 19.","DOI":"10.1128\/CMR.00001-19"},{"issue":"10","key":"4470_CR3","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1001\/archinte.1986.00360220057011","volume":"146","author":"YC Liu","year":"1986","unstructured":"Liu YC, Cheng DL, Lin CL (1986 Oct) Klebsiella pneumoniae liver abscess associated with septic endophthalmitis. 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Nat Commun 9(1):2703\u2013018\u201305114\u20137","DOI":"10.1038\/s41467-018-05114-7"},{"key":"4470_CR6","unstructured":"European Centre for Disease Prevention and Control (2021) Emergence of hypervirulent Klebsiella pneumoniae ST23 carrying carbapenemase genes in EU\/EEA countries. 17 March 2021. ECDC: Stockholm; available from https:\/\/www.ecdc.europa.eu\/sites\/default\/files\/documents\/Emergence-of-hypervirulent-Klebsiella-pneumoniae-ST23-carrying-carbapenemase-genes.pdf"},{"key":"4470_CR7","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.2147\/IDR.S252637","volume":"13","author":"J Hirai","year":"2020","unstructured":"Hirai J, Sakanashi D, Kinjo T, Haranaga S, Fujita J (2020) The first case of community-acquired pneumonia due to capsular genotype K2-ST86 hypervirulent Klebsiella pneumoniae in Okinawa, Japan: a case report and literature review. Infect Drug Resist 13:2237\u20132243","journal-title":"Infect Drug Resist"},{"key":"4470_CR8","doi-asserted-by":"publisher","unstructured":"Valente-Acosta B, Vigil-Escalera-Bejarano M, Ochoa-Ramirez CA, Hoyo-Ulloa I (2022) Hypermucoviscous Klebsiella pneumoniae invasive syndrome in a patient with diabetes without liver abscess. BMJ Case Rep 15(4):e250146. https:\/\/doi.org\/10.1136\/bcr-2022-250146","DOI":"10.1136\/bcr-2022-250146"},{"issue":"5","key":"4470_CR9","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000512","volume":"7","author":"APA Hendrickx","year":"2021","unstructured":"Hendrickx APA, Landman F, de Haan A, Witteveen S, van Santen-Verheuvel MG, Schouls LM et al (2021 May) bla (OXA-48)-like genome architecture among carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in the Netherlands. 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Antibiotics (Basel) 9(12):862. https:\/\/doi.org\/10.3390\/antibiotics9120862","journal-title":"Antibiotics (Basel)"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-022-04470-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-022-04470-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-022-04470-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T17:21:35Z","timestamp":1657041695000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-022-04470-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,5]]},"references-count":16,"alternative-id":["4470"],"URL":"https:\/\/doi.org\/10.1007\/s10096-022-04470-z","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,5]]},"assertion":[{"value":"28 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 June 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 July 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This is a retrospective case series. The University Medical Center Groningen Research Ethics Committee has confirmed that no ethical approval is required for casuistics.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"In this retrospective case series, no patient informed consent has been obtained since both patients were deceased at the time of writing. Under certain conditions, to which this study fulfills, it is allowed to present cases anonymously without patient consent according to the Dutch law.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}