{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:05:21Z","timestamp":1790949921841,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1007\/s10096-022-04489-2","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T18:52:57Z","timestamp":1662144777000},"page":"1237-1243","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Retrospective analysis of a large single cohort of Enterobacteriaceae producing extended-spectrum B-lactamase (E-ESBL) patients: incidence, microbiology, and mortality"],"prefix":"10.1007","volume":"41","author":[{"given":"Camille","family":"Bouchand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Andr\u00e9o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Le Gallou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Corvec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Bourigault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9054-907X","authenticated-orcid":false,"given":"Didier","family":"Lepelletier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,2]]},"reference":[{"key":"4489_CR1","unstructured":"European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe: annual report of the European Antimicrobial Resistance Surveillance Network (EARS Net) 2015. LU: Publications Office; 2017 Available at: https:\/\/data.europa.eu\/doi\/10.2900\/6928\u00a0. Accessed March 8, 2022."},{"issue":"11","key":"4489_CR2","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1051\/medsci\/20092511939","volume":"25","author":"J-R Zahar","year":"2009","unstructured":"Zahar J-R, Bille E, Schnell D, Lanternier F, Mechai F, Masse V et al (2009) Extension of beta-lactamases producing bacteria is a worldwide concern. Med Sci (Paris) 25(11):939\u2013944","journal-title":"Med Sci (Paris)"},{"key":"4489_CR3","doi-asserted-by":"crossref","unstructured":"Coque TM, Baquero F, Canton R (2008) Increasing prevalence of ESBL-producing Enterobacteriaceae in Europe. Euro Surveill 13(47).","DOI":"10.2807\/ese.13.47.19044-en"},{"key":"4489_CR4","unstructured":"Observatoire National de l\u2019Epid\u00e9miologie de la Resistance Bact\u00e9rienne aux Antibiotiques. Rapport d\u2019activit\u00e9 annuel 2017. Available at: http:\/\/onerba-doc.onerba.org\/Rapports\/Rapport-ONERBA-2017\/ONERBA_rapport_2017.pdf. Accessed March 8, 2022."},{"key":"4489_CR5","doi-asserted-by":"crossref","unstructured":"Arnaud I, Maugat S, Jarlier V, Astagneau P, National Early Warning, Investigation and Surveillance of Healthcare-Associated Infections Network (RAISIN)\/multidrug resistance study group (2015) Ongoing increasing temporal and geographical trends of the incidence of extended-spectrum beta-lactamase-producing Enterobacteriaceae infections in France, 2009 to 2013. Euro Surveill 20(36).","DOI":"10.2807\/1560-7917.ES.2015.20.36.30014"},{"issue":"8","key":"4489_CR6","doi-asserted-by":"publisher","first-page":"2796","DOI":"10.1128\/JCM.01008-08","volume":"46","author":"A Valverde","year":"2008","unstructured":"Valverde A, Grill F, Coque TM, Pintado V, Baquero F, Cant\u00f3n R et al (2008) High rate of intestinal colonization with extended-spectrum-\u03b2-lactamase-producing organisms in household contacts of infected community patients. J Clin Microbiol 46(8):2796\u20132799","journal-title":"J Clin Microbiol"},{"issue":"6","key":"4489_CR7","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1093\/jac\/dkn362","volume":"62","author":"S Boyer-Mariotte","year":"2008","unstructured":"Boyer-Mariotte S, Duboc P, Bonacorsi S, Lemeland J-F, Bingen E, Pinquier D (2008) CTX-M-15-producing Escherichia coli in fatal neonatal meningitis: failure of empirical chemotherapy. J Antimicrob Chemother 62(6):1472\u20131474","journal-title":"J Antimicrob Chemother"},{"issue":"3","key":"4489_CR8","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1128\/JCM.42.3.1089-1094.2004","volume":"42","author":"J Rodr\u00edguez-Ba\u00f1o","year":"2004","unstructured":"Rodr\u00edguez-Ba\u00f1o J, Navarro MD, Romero L, Mart\u00ednez-Mart\u00ednez L, Muniain MA, Perea EJ et al (2004) Epidemiology and clinical features of infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in non hospitalized patients. J Clin Microbiol 42(3):1089\u20131094","journal-title":"J Clin Microbiol"},{"key":"4489_CR9","unstructured":"Sant\u00e9 Publique France. Bact\u00e9ries multir\u00e9sistantes en \u00e9tablissements de sant\u00e9 en 2018 Mission nationale Spares, novembre 2019. Donn\u00e9es 2018 du r\u00e9seau BMR-Raisin. Availble at: \/import\/bacteries-multiresistantes-en-etablissements-de-sante-en-2018-mission-nationale-spares-novembre-2019.-donnees-2018-du-reseau-bmr-raisin. Accessed March 8, 2022."},{"issue":"1","key":"4489_CR10","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/S1473-3099(10)70258-9","volume":"11","author":"M-L Lambert","year":"2011","unstructured":"Lambert M-L, Suetens C, Savey A, Palomar M, Hiesmayr M, Morales I et al (2011) Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study. Lancet Infect Dis 11(1):30\u201338","journal-title":"Lancet Infect Dis"},{"issue":"12","key":"4489_CR11","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1007\/s00134-015-4138-x","volume":"42","author":"F Barbier","year":"2016","unstructured":"Barbier F, Lisboa T, Nseir S (2016) Understanding why resistant bacteria are associated with higher mortality in ICU patients. Intensive Care Med 42(12):2066\u20132069","journal-title":"Intensive Care Med"},{"issue":"1","key":"4489_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jinf.2018.03.005","volume":"77","author":"JF McNamara","year":"2018","unstructured":"McNamara JF, Righi E, Wright H, Hartel GF, Harris PNA, Paterson DL (2018) Long-term morbidity and mortality following bloodstream infection: a systematic literature review. J Infect 77(1):1\u20138","journal-title":"J Infect"},{"issue":"6","key":"4489_CR13","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.arcmed.2005.02.005","volume":"36","author":"GML Bearman","year":"2005","unstructured":"Bearman GML, Wenzel RP (2005) Bacteremias: a leading cause of death. Arch Med Res 36(6):646\u2013659","journal-title":"Arch Med Res"},{"issue":"3","key":"4489_CR14","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1086\/421946","volume":"39","author":"H Wisplinghoff","year":"2004","unstructured":"Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB (2004) Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 39(3):309\u2013317","journal-title":"Clin Infect Dis"},{"issue":"2","key":"4489_CR15","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1093\/jac\/dkq412","volume":"66","author":"MEA de Kraker","year":"2011","unstructured":"de Kraker MEA, Wolkewitz M, Davey PG, Koller W, Berger J, Nagler J et al (2011) Burden of antimicrobial resistance in European hospitals: excess mortality and length of hospital stay associated with bloodstream infections due to Escherichia coli resistant to third-generation cephalosporins. J Antimicrob Chemother 66(2):398\u2013407","journal-title":"J Antimicrob Chemother"},{"issue":"5","key":"4489_CR16","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1007\/s10096-008-0656-6","volume":"28","author":"L Drieux","year":"2009","unstructured":"Drieux L, Brossier F, Duquesnoy O, Aubry A, Robert J, Sougakoff W et al (2009) Increase in hospital-acquired bloodstream infections caused by extended spectrum beta-lactamase-producing Escherichia coli in a large French teaching hospital. Eur J Clin Microbiol Infect Dis 28(5):491\u2013498","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"4489_CR17","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jhin.2015.10.001","volume":"92","author":"JA Maslikowska","year":"2016","unstructured":"Maslikowska JA, Walker SAN, Elligsen M, Mittmann N, Palmay L, Daneman N et al (2016) Impact of infection with extended-spectrum \u03b2-lactamase-producing Escherichia coli or Klebsiella species on outcome and hospitalization costs. J Hosp Infect 92(1):33\u201341","journal-title":"J Hosp Infect"},{"issue":"4","key":"4489_CR18","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1002\/jhm.2157","volume":"9","author":"SH MacVane","year":"2014","unstructured":"MacVane SH, Tuttle LO, Nicolau DP (2014) Impact of extended-spectrum \u03b2-lactamase-producing organisms on clinical and economic outcomes in patients with urinary tract infection. J Hosp Med 9(4):232\u2013238","journal-title":"J Hosp Med"},{"issue":"1","key":"4489_CR19","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.jhin.2019.01.001","volume":"102","author":"A No\u00ebl","year":"2019","unstructured":"No\u00ebl A, Vastrade C, Dupont S, de Barsy M, Huang TD, Van Maerken T et al (2019) Nosocomial outbreak of extended-spectrum \u03b2-lactamase-producing Enterobacter cloacae among cardiothoracic surgical patients: causes and consequences. J Hosp Infect 102(1):54\u201360","journal-title":"J Hosp Infect"},{"key":"4489_CR20","unstructured":"Haut Conseil de la sant\u00e9 publique (HCSP). Pr\u00e9venir l\u2019\u00e9mergence des ent\u00e9robact\u00e9ries BLSE et lutter contre leur diss\u00e9mination [Internet]. Rapport de l\u2019HCSP. Paris: Haut Conseil de la Sant\u00e9 Publique; 2010. Available at: https:\/\/www.hcsp.fr\/explore.cgi\/avisrapportsdomaine?clefr=162. Accessed March 8, 2022."},{"key":"4489_CR21","unstructured":"Soci\u00e9t\u00e9 fran\u00e7aise d\u2019hygi\u00e8ne hospitali\u00e8re (2009) Recommandations nationales - Pr\u00e9vention de la transmission crois\u00e9e\u202f: pr\u00e9cautions compl\u00e9mentaires contact - Consensus formalis\u00e9 d\u2019experts - 2009;60."},{"issue":"4","key":"4489_CR22","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1093\/jac\/dks464","volume":"68","author":"A Carbonne","year":"2013","unstructured":"Carbonne A, Arnaud I, Maugat S, Marty N, Dumartin C, Bertrand X et al (2013) National multidrug-resistant bacteria (MDRB) surveillance in France through the RAISIN network: a 9 year experience. J Antimicrob Chemother 68(4):954\u2013959","journal-title":"J Antimicrob Chemother"},{"issue":"6","key":"4489_CR23","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1001\/archinternmed.2010.32","volume":"170","author":"V Jarlier","year":"2010","unstructured":"Jarlier V, Trystram D, Brun-Buisson C, Fournier S, Carbonne A, Marty L et al (2010) Curbing methicillin-resistant Staphylococcus aureus in 38 French hospitals through a 15-year institutional control program. Arch Intern Med 170(6):552\u2013559","journal-title":"Arch Intern Med"},{"key":"4489_CR24","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/2047-2994-3-9","volume":"3","author":"SZ Kassakian","year":"2014","unstructured":"Kassakian SZ, Mermel LA (2014) Changing epidemiology of infections due to extended spectrum beta-lactamase producing bacteria. Antimicrob Resist Infect Control 3:9","journal-title":"Antimicrob Resist Infect Control"},{"issue":"3","key":"4489_CR25","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.ajic.2017.08.031","volume":"46","author":"AR Marra","year":"2018","unstructured":"Marra AR, Edmond MB, Schweizer ML, Ryan GW, Diekema DJ (2018) Discontinuing contact precautions for multidrug-resistant organisms: a systematic literature review and meta-analysis. Am J Infect Control 46(3):333\u2013340","journal-title":"Am J Infect Control"},{"issue":"Suppl 1","key":"4489_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/1469-0691.12427","volume":"20","author":"E Tacconelli","year":"2014","unstructured":"Tacconelli E, Cataldo MA, Dancer SJ, De Angelis G, Falcone M, Frank U et al (2014) ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients. Clin Microbiol Infect 20(Suppl 1):1\u201355","journal-title":"Clin Microbiol Infect"},{"issue":"6","key":"4489_CR27","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1086\/597090","volume":"48","author":"KB Kirkland","year":"2009","unstructured":"Kirkland KB, Weinstein RA (2009) Taking off the gloves: toward a less dogmatic approach to the use of contact isolation. Clin Infect Dis 48(6):766\u2013771","journal-title":"Clin Infect Dis"},{"issue":"10","key":"4489_CR28","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/S1473-3099(19)30262-2","volume":"19","author":"MFQ Kluytmans-van den Bergh","year":"2019","unstructured":"Kluytmans-van den Bergh MFQ, Bruijning-Verhagen PCJ, Vandenbroucke-Grauls CMJE, de Brauwer EIGB, Buiting AGM, Diederen BM et al (2019) Contact precautions in single-bed or multiple-bed rooms for patients with extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae in Dutch hospitals: a cluster-randomised, crossover, non-inferiority study. Lancet Infect Dis 19(10):1069\u201379","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"4489_CR29","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1186\/s12879-015-1244-x","volume":"15","author":"J-R Zahar","year":"2015","unstructured":"Zahar J-R, Poirel L, Dupont C, Fortineau N, Nassif X, Nordmann P (2015) About the usefulness of contact precautions for carriers of extended-spectrum beta-lactamase-producing Escherichia coli. BMC Infect Dis 15(1):512","journal-title":"BMC Infect Dis"},{"issue":"6","key":"4489_CR30","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1017\/ice.2018.63","volume":"39","author":"O Scheuerman","year":"2018","unstructured":"Scheuerman O, Schechner V, Carmeli Y, Guti\u00e9rrez-Guti\u00e9rrez B, Calbo E, Almirante B et al (2018) Comparison of predictors and mortality between bloodstream infections caused by ESBL-producing Escherichia coli and ESBL-producing Klebsiella pneumoniae. Infect Control Hosp Epidemiol 39(6):660\u2013667","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"6","key":"4489_CR31","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1007\/s15010-014-0670-9","volume":"42","author":"R Leistner","year":"2014","unstructured":"Leistner R, G\u00fcrntke S, Sakellariou C, Denkel LA, Bloch A, Gastmeier P et al (2014) Bloodstream infection due to extended-spectrum beta-lactamase (ESBL)-positive K. pneumoniae and E. coli: an analysis of the disease burden in a large cohort. Infection 42(6):991\u20137","journal-title":"Infection"},{"issue":"7","key":"4489_CR32","doi-asserted-by":"publisher","first-page":"e0158039","DOI":"10.1371\/journal.pone.0158039","volume":"11","author":"C Sakellariou","year":"2016","unstructured":"Sakellariou C, G\u00fcrntke S, Steinmetz I, Kohler C, Pfeifer Y, Gastmeier P et al (2016) Sepsis caused by extended-spectrum beta-lactamase (ESBL)-positive K. pneumoniae and E. coli: comparison of severity of sepsis, delay of anti-infective therapy and ESBL genotype. PLoS One 11(7):e0158039","journal-title":"PLoS One"},{"key":"4489_CR33","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s13756-016-0138-z","volume":"5","author":"R Leistner","year":"2016","unstructured":"Leistner R, Bloch A, Gastmeier P, Schwab FE (2016) coli bacteremia in comparison to K. pneumoniae bacteremia: influence of pathogen species and ESBL production on 7-day mortality. Antimicrob Resist Infect Control 5:37","journal-title":"Antimicrob Resist Infect Control"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-022-04489-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-022-04489-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-022-04489-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T11:25:21Z","timestamp":1663673121000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-022-04489-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,2]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["4489"],"URL":"https:\/\/doi.org\/10.1007\/s10096-022-04489-2","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,2]]},"assertion":[{"value":"31 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"We declared that compliance with ethical standard was followed during the study period.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All the authors have declared their consent for publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}