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To evaluate this possibility, our study investigated and characterized all\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    isolates harboring both the\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>OXA-23<\/jats:sub>\n                    and\n                    <jats:italic>armA<\/jats:italic>\n                    genes that had been collected at the Swiss National Reference Center for Emerging Antibiotic Resistance (NARA) from 2020 to 2021. Most isolates were obtained from infections rather than colonization with the majority being obtained from respiratory specimens. Pulsed-field gel electrophoresis (PFGE) analysis of 56 isolates identified nine profiles. Then, whole-genome sequencing that was performed on a subset of 11 isolates including at least one representative isolate of each PFGE profile identified three STs; one each of ST25 and ST1902, and nine ST2 (a member of Global Clone 2 (GC-2). The\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>OXA-23<\/jats:sub>\n                    gene was always found embedded within Tn\n                    <jats:italic>2006<\/jats:italic>\n                    structures, as commonly described with GC-2 (ST2) isolates. Susceptibility testing showed that most of those isolates, despite being highly resistant to all carbapenems and all aminoglycosides, remained susceptible to colistin (94.6%), sulbactam-durlobactam (87.5%), and cefiderocol (83.9% or 91.1% according to EUCAST or CLSI breakpoints, respectively). Overall, this study identified that the\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    co-producing OXA-23 and ArmA are increasing in incidence in Switzerland, largely due to the dissemination of the high-risk GC-2. This highlights the importance of the\u00a0monitoring of such MDR\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    strains, in order to contribute to reduce their potential further spread.\n                  <\/jats:p>","DOI":"10.1007\/s10096-023-04643-4","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T01:01:36Z","timestamp":1689814896000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Dissemination of ArmA- and OXA-23-co-producing Acinetobacter baumannii Global Clone 2 in Switzerland, 2020\u20132021"],"prefix":"10.1007","author":[{"given":"Jacqueline","family":"Findlay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Nordmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Bouvier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Auriane","family":"Kerbol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5160-5286","authenticated-orcid":false,"given":"Laurent","family":"Poirel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,7,20]]},"reference":[{"issue":"10","key":"4643_CR1","doi-asserted-by":"publisher","first-page":"e000306","DOI":"10.1099\/mgen.0.000306","volume":"5","author":"M Hamidian","year":"2019","unstructured":"Hamidian M, Nigro SJ (2019) Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii. 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