{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:04:07Z","timestamp":1787065447596,"version":"build-2736575974"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Construction of High-level Hospitals in Guangdong Province","award":["G330102097011"],"award-info":[{"award-number":["G330102097011"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Antibiotic-resistant\n                    <jats:italic>Acinetobacter baumannii<\/jats:italic>\n                    (\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    ) is a common cause of hospital-acquired infections. This study aimed to identify independent factors associated with progression from nosocomial pneumonia to bacteremia in patients infected with carbapenem-resistant\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    (CR-AB). From 2019 to 2021, we conducted a retrospective anaylsis of the medical records of 159 nosocomial CR-AB pneumonia patients in our Intensive Care Unit (ICU). We employed both univariate and multivariable logistic regression models to identify factors associated with the progression of nosocomial CR-AB pneumonia to bacteremia. Among the 159 patients with nosocomial CR-AB pneumonia, 40 experienced progression to bacteremia and 38 died within 28\u00a0days following diagnosis. Patients who developed bacteremia had a significantly higher 28-day mortality rate compared to those without bloodstream infection (47.50% vs. 15.97%). Multivariable logistic regression revealed that higher levels of C-Reactive protein (CRP) (OR\u2009=\u20091.01) and the use of continuous veno-venous hemofiltration (CVVH) treatment (OR\u2009=\u20092.93) were independently associated with an elevated risk of developing bacteremia. Among patients who developed bloodstream infection, those who died within 28\u00a0days exhibited significantly higher level of interleukin-6 (IL-6), a greater frequency of antifungal drugs usage, and a longer duration of machanical ventilation compared to survivors. Furthermore, the use of antifungal drugs was the only factor that associated with 28-day mortality (OR\u2009=\u20094.70). In ICU patients with central venous catheters who have CR-AB pneumonia and are on mechanical ventilation, higher CRP levels and CVVH treatment are risk factors for developing bacteremia. Among patients with bacteremia, the use of antifungal drugs is associated with 28-day mortality.\n                  <\/jats:p>","DOI":"10.1007\/s10096-023-04668-9","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T01:01:31Z","timestamp":1695862891000},"page":"1337-1346","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Risk factors for progression to bacteremia among patients with nosocomial carbapenem-resistant Acinetobacter baumannii pneumonia in the Intensive Care Unit"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8963-440X","authenticated-orcid":false,"given":"Haiming","family":"Niu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqing","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongkai","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guishen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoqing","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaolian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,9,28]]},"reference":[{"key":"4668_CR1","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.2147\/IDR.S166750","volume":"11","author":"M Asif","year":"2018","unstructured":"Asif M, Alvi IA, Ur Rehman S (2018) Insight into Acinetobacter baumannii: Pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities. Infect Drug Resist 11:1249\u20131260","journal-title":"Infect Drug Resist"},{"issue":"4","key":"4668_CR2","doi-asserted-by":"publisher","first-page":"205","DOI":"10.3390\/antibiotics9040205","volume":"9","author":"R V\u00e1zquez-L\u00f3pez","year":"2020","unstructured":"V\u00e1zquez-L\u00f3pez R, Solano-G\u00e1lvez SG, Vignon-Whaley JJJ, Vaamonde JAA, Alonzo LAP, Res\u00e9ndiz AR et al (2020) Acinetobacter baumannii resistance: A real challenge for clinicians. Antibiotics 9(4):205","journal-title":"Antibiotics"},{"issue":"4","key":"4668_CR3","first-page":"1545","volume":"9","author":"W Liu","year":"2020","unstructured":"Liu W, Yang Y, Zhang K, Hai Y, Li H, Jiao Y et al (2020) Drug resistance of healthcare-associated pathogenic bacteria and carbapenem-resistant Acinetobacter baumannii homology in the general intensive care unit. Ann Cardiothorac Surg 9(4):1545\u20131555","journal-title":"Ann Cardiothorac Surg"},{"issue":"1","key":"4668_CR4","doi-asserted-by":"publisher","first-page":"11087","DOI":"10.1038\/s41598-022-15397-y","volume":"12","author":"W Jiang","year":"2022","unstructured":"Jiang W, Li L, Wen S, Song Y, Yu L, Tan B (2022) Gram-negative multidrug-resistant organisms were dominant in neurorehabilitation ward patients in a general hospital in southwest China. Sci Rep 12(1):11087","journal-title":"Sci Rep"},{"key":"4668_CR5","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.jgar.2020.09.019","volume":"23","author":"A Oliva","year":"2020","unstructured":"Oliva A, Ceccarelli G, De Angelis M, Sacco F, Miele MC, Mastroianni CM et al (2020) Cefiderocol for compassionate use in the treatment of complicated infections caused by extensively and pan-resistant Acinetobacter baumannii. J Glob Antimicrob Resist 23:292\u2013296","journal-title":"J Glob Antimicrob Resist"},{"issue":"8","key":"4668_CR6","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1016\/j.cmi.2019.03.014","volume":"25","author":"ET Piperaki","year":"2019","unstructured":"Piperaki ET, Tzouvelekis LS, Miriagou V, Daikos GL (2019) Carbapenem-resistant Acinetobacter baumannii: in pursuit of an effective treatment. Clin Microbiol Infect 25(8):951\u2013957","journal-title":"Clin Microbiol Infect"},{"issue":"12","key":"4668_CR7","doi-asserted-by":"publisher","first-page":"e0209367","DOI":"10.1371\/journal.pone.0209367","volume":"13","author":"KE Da Silva","year":"2018","unstructured":"Da Silva KE, Maciel WG, Croda J, Cay\u00f4 R, Ramos AC, De Sales RO et al (2018) A high mortality rate associated with multidrug-resistant Acinetobacter baumannii ST79 and ST25 carrying OXA-23 in a Brazilian intensive care unit. PLoS ONE 13(12):e0209367","journal-title":"PLoS ONE"},{"issue":"5","key":"4668_CR8","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1017\/ice.2018.58","volume":"39","author":"N Teerawattanapong","year":"2018","unstructured":"Teerawattanapong N, Panich P, Kulpokin D, Na Ranong S, Kongpakwattana K, Saksinanon A et al (2018) A systematic review of the burden of multidrug-resistant healthcare-associated infections among intensive care unit patients in southeast asia: The rise of multidrug-resistant Acinetobacter baumannii. Infect Control Hosp Epidemiol 39(5):525\u2013533","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"4","key":"4668_CR9","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.diagmicrobio.2012.04.007","volume":"73","author":"AC Gales","year":"2012","unstructured":"Gales AC, Castanheira M, Jones RN, Sader HS (2012) Antimicrobial resistance among Gram-negative bacilli isolated from Latin America: Results from SENTRY Antimicrobial Surveillance Program (Latin America, 2008\u20132010). Diagn Microbiol Infect Dis 73(4):354\u2013360","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"4","key":"4668_CR10","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.ijantimicag.2012.01.002","volume":"39","author":"P Kiratisin","year":"2012","unstructured":"Kiratisin P, Chongthaleong A, Tan TY, Lagamayo E, Roberts S, Garcia J et al (2012) Comparative in vitro activity of carbapenems against major Gram-negative pathogens: Results of Asia-Pacific surveillance from the COMPACT II study. Int J Antimicrob Agents 39(4):311\u2013316","journal-title":"Int J Antimicrob Agents"},{"issue":"8","key":"4668_CR11","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1086\/529198","volume":"46","author":"LL Maragakis","year":"2008","unstructured":"Maragakis LL, Perl TM (2008) Acinetobacter baumannii: Epidemiology, antimicrobial resistance, and treatment options. Clin Infect Dis 46(8):1254\u20131263","journal-title":"Clin Infect Dis"},{"issue":"3","key":"4668_CR12","doi-asserted-by":"publisher","first-page":"119","DOI":"10.3390\/antibiotics9030119","volume":"9","author":"CA Moubareck","year":"2020","unstructured":"Moubareck CA, Halat DH (2020) Insights into Acinetobacter baumannii: A review of microbiological, virulence, and resistance traits in a threatening nosocomial pathogen. Antibiotics 9(3):119","journal-title":"Antibiotics"},{"issue":"6","key":"4668_CR13","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/j.jinf.2019.09.012","volume":"79","author":"S Mohd Sazlly Lim","year":"2019","unstructured":"Mohd Sazlly Lim S, Zainal Abidin A, Liew SM, Roberts JA, Sime FB (2019) The global prevalence of multidrug-resistance among Acinetobacter baumannii causing hospital-acquired and ventilator-associated pneumonia and its associated mortality: A systematic review and meta-analysis. J Infect 79(6):593\u2013600","journal-title":"J Infect"},{"issue":"6","key":"4668_CR14","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1016\/j.jmii.2014.10.006","volume":"49","author":"CP Liu","year":"2016","unstructured":"Liu CP, Shih SC, Wang NY, Wu AY, Sun FJ, Chow SF et al (2016) Risk factors of mortality in patients with carbapenem-resistant Acinetobacter baumannii bacteremia. J Microbiol Immunol Infect 49(6):934\u2013940","journal-title":"J Microbiol Immunol Infect"},{"issue":"2","key":"4668_CR15","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jhin.2009.06.007","volume":"73","author":"TN Jang","year":"2009","unstructured":"Jang TN, Lee SH, Huang CH, Lee CL, Chen WY (2009) Risk factors and impact of nosocomial Acinetobacter baumannii bloodstream infections in the adult intensive care unit: a case-control study. J Hosp Infect 73(2):143\u2013150","journal-title":"J Hosp Infect"},{"key":"4668_CR16","doi-asserted-by":"publisher","first-page":"861","DOI":"10.2147\/IDR.S163944","volume":"11","author":"A Mart\u00edn-Aspas","year":"2018","unstructured":"Mart\u00edn-Aspas A, Guerrero-S\u00e1nchez FM, Garc\u00eda-Colchero F, Rodr\u00edguez-Roca S, Gir\u00f3n-Gonz\u00e1lez JA (2018) Differential characteristics of Acinetobacter baumannii colonization and infection: Risk factors, clinical picture, and mortality. Infect Drug Resist 11:861\u2013872","journal-title":"Infect Drug Resist"},{"issue":"1","key":"4668_CR17","first-page":"e01631","volume":"62","author":"N Blanco","year":"2017","unstructured":"Blanco N, Harris AD, Rock C, Johnson JK, Pineles L, Bonomo RA et al (2017) Risk factors and outcomes associated with multidrug- resistant Acinetobacter baumannii upon intensive care unit admission. Antimicrob Agents Chemother 62(1):e01631-e1717","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"4668_CR18","doi-asserted-by":"publisher","first-page":"e75","DOI":"10.18295\/squmj.2018.18.01.012","volume":"18","author":"AM Sultan","year":"2018","unstructured":"Sultan AM, Seliem WA (2018) Identifying risk factors for healthcare-associated infections caused by carbapenem-resistant Acinetobacter baumannii in a neonatal intensive care unit. Sultan Qaboos Univ Med J 18(1):e75\u2013e80","journal-title":"Sultan Qaboos Univ Med J"},{"key":"4668_CR19","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.ijid.2018.11.371","volume":"79","author":"AL Munier","year":"2019","unstructured":"Munier AL, Biard L, Legrand M, Rousseau C, Lafaurie M, Donay JL et al (2019) Incidence, risk factors and outcome of multi-drug resistant Acinetobacter baumannii nosocomial infections during an outbreak in a burn unit. Int J Infect Dis 79:179\u2013184","journal-title":"Int J Infect Dis"},{"issue":"1","key":"4668_CR20","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s12879-017-2932-5","volume":"18","author":"H Huang","year":"2018","unstructured":"Huang H, Chen B, Liu G, Ran J, Lian X, Huang X et al (2018) A multi-center study on the risk factors of infection caused by multi-drug resistant Acinetobacter baumannii. BMC Infect Dis 18(1):11","journal-title":"BMC Infect Dis"},{"issue":"10","key":"4668_CR21","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.12998\/wjcc.v7.i10.1111","volume":"7","author":"H Aydemir","year":"2019","unstructured":"Aydemir H, T\u00fcz HI, Piskin N, Celebi G, Kulah C, Kokturk F (2019) Risk factors and clinical responses of pneumonia patients with colistin-resistant Acinetobacter baumannii-calcoaceticus. World J Clin Cases 7(10):1111\u20131121","journal-title":"World J Clin Cases"},{"issue":"7","key":"4668_CR22","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1080\/23744235.2018.1556400","volume":"51","author":"DH Oh","year":"2019","unstructured":"Oh DH, Kim YC, Kim EJ, Jung IY, Jeong SJ, Kim SY et al (2019) Multidrug-resistant Acinetobacter baumannii infection in lung transplant recipients: risk factors and prognosis. Infect Dis (Auckl) 51(7):493\u2013501","journal-title":"Infect Dis (Auckl)"},{"issue":"3","key":"4668_CR23","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1177\/0300060517706284","volume":"45","author":"MM Al-Gethamy","year":"2017","unstructured":"Al-Gethamy MM, Faidah HS, Adetunji HA, Haseeb A, Ashgar SS, Mohanned TK et al (2017) Risk factors associated with multi-drug-resistant Acinetobacter baumannii nosocomial infections at a tertiary care hospital in Makkah, Saudi Arabia - a matched case\u2013control study. J Int Med Res 45(3):1181\u20131189","journal-title":"J Int Med Res"},{"issue":"5","key":"4668_CR24","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.ajic.2019.07.025","volume":"48","author":"SY Kim","year":"2020","unstructured":"Kim SY, Cho SL, Bang JH (2020) Risk factors associated with bloodstream infection among patients colonized by multidrug-resistant Acinetobacter baumannii: A 7-year observational study in a general hospital. Am J Infect Control 48(5):581\u2013583","journal-title":"Am J Infect Control"},{"issue":"5","key":"4668_CR25","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1093\/cid\/ciw353","volume":"63","author":"AC Kalil","year":"2016","unstructured":"Kalil AC, Metersky ML, Klompas M, Muscedere J, Sweeney DA, Palmer LB et al (2016) Management of Adults with Hospital-acquired and Ventilator-associated Pneumonia: 2016 ClinicalPractice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis 63(5):e61\u2013e111","journal-title":"Clin Infect Dis"},{"issue":"5","key":"4668_CR26","first-page":"525","volume":"48","author":"SO Teng","year":"2015","unstructured":"Teng SO, Yen MY, Ou TY, Chen FL, Yu FL, Lee WS (2015) Comparison of pneumonia- and non-pneumonia-related Acinetobacter baumannii bacteremia: Impact on empiric therapy and antibiotic resistance. J MicrobiolImmunol Infect 48(5):525\u2013530","journal-title":"J MicrobiolImmunol Infect"},{"key":"4668_CR27","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.2147\/IDR.S169432","volume":"11","author":"T Niu","year":"2018","unstructured":"Niu T, Xiao T, Guo L, Yu W, Chen Y, Zheng B et al (2018) Retrospective comparative analysis of risk factors and outcomes in patients with carbapenem-resistant Acinetobacter baumannii bloodstream infections: Cefoperazone\u2013sulbactam associated with resistance and tigecycline increased the mortality. Infect Drug Resist 11:2021\u20132030","journal-title":"Infect Drug Resist"},{"issue":"7","key":"4668_CR28","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1099\/jmm.0.001222","volume":"69","author":"Y Liu","year":"2020","unstructured":"Liu Y, Wang Q, Zhao C, Chen H, Li H, Wang H et al (2020) Prospective multi-center evaluation on risk factors, clinical characteristics and outcomes due to carbapenem resistance in Acinetobacter baumannii complex bacteraemia: Experience from the Chinese Antimicrobial Resistance Surveillance of Nosocomial Infections (CARES) Network. J Med Microbiol 69(7):949\u2013959","journal-title":"J Med Microbiol"},{"issue":"13","key":"4668_CR29","doi-asserted-by":"publisher","first-page":"e14937","DOI":"10.1097\/MD.0000000000014937","volume":"98","author":"H Zhou","year":"2019","unstructured":"Zhou H, Yao Y, Zhu B, Ren D, Yang Q, Fu Y et al (2019) Risk factors for acquisition and mortality of multidrug-resistant Acinetobacter baumannii bacteremia: A retrospective study from a Chinese hospital. Medicine (Baltimore) 98(13):e14937","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"4668_CR30","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.ijid.2007.03.005","volume":"12","author":"G Baran","year":"2008","unstructured":"Baran G, Erbay A, Bodur H, \u00d6ng\u00fcr\u00fc P, Akinci E, Balaban N et al (2008) Risk factors for nosocomial imipenem-resistant Acinetobacter baumannii infections. Int J Infect Dis 12(1):16\u201321","journal-title":"Int J Infect Dis"},{"issue":"2","key":"4668_CR31","doi-asserted-by":"publisher","first-page":"115229","DOI":"10.1016\/j.diagmicrobio.2020.115229","volume":"99","author":"Y Gu","year":"2021","unstructured":"Gu Y, Jiang Y, Zhang W, Yu Y, He X, Tao J et al (2021) Risk factors and outcomes of bloodstream infections caused by Acinetobacter baumannii: a case-control study. Diagn Micr Infect Dis 99(2):115229","journal-title":"Diagn Micr Infect Dis"},{"key":"4668_CR32","doi-asserted-by":"publisher","first-page":"e38","DOI":"10.1017\/S0950268820000291","volume":"148","author":"OS Garvik","year":"2020","unstructured":"Garvik OS, P\u00f3voa P, Magnussen B, Vinholt PJ, Pedersen C, Jensen TG et al (2020) C-reactive protein and albumin kinetics before community-acquired bloodstream infections- A Danish population-based cohort study. Epidemiol Infect 148:e38","journal-title":"Epidemiol Infect"},{"issue":"3","key":"4668_CR33","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1177\/0310057X0903700319","volume":"37","author":"KM Ho","year":"2009","unstructured":"Ho KM, Towler SC (2009) A comparison of eosinopenia and C-reactive protein as a marker of bloodstream infections in critically ill patients: A case control study. Anaesth Intensive Care 37(3):450\u2013456","journal-title":"Anaesth Intensive Care"},{"issue":"9","key":"4668_CR34","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1016\/j.ajic.2019.03.003","volume":"47","author":"X Du","year":"2019","unstructured":"Du X, Xu X, Yao J, Deng K, Chen S, Shen Z et al (2019) Predictors of mortality in patients infected with carbapenem-resistant Acinetobacter baumannii: A systematic review and meta-analysis. Am J Infect Control 47(9):1140\u20131145","journal-title":"Am J Infect Control"},{"key":"4668_CR35","doi-asserted-by":"publisher","first-page":"405","DOI":"10.3389\/fimmu.2017.00405","volume":"8","author":"H Su","year":"2017","unstructured":"Su H, Lei CT, Zhang C (2017) Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An Update. Front Immunol 8:405","journal-title":"Front Immunol"},{"issue":"4","key":"4668_CR36","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1093\/cid\/civ933","volume":"62","author":"PG Pappas","year":"2016","unstructured":"Pappas PG, Kauffman CA, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Reboli AC et al (2016) Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis 62(4):e1-50","journal-title":"Clin Infect Dis"},{"issue":"3","key":"4668_CR37","doi-asserted-by":"publisher","first-page":"325","DOI":"10.3947\/ic.2013.45.3.325","volume":"45","author":"SY Park","year":"2013","unstructured":"Park SY, Choo JW, Kwon SH, Yu SN, Lee EJ, Kim TH et al (2013) Risk factors for mortality in patients with Acinetobacter baumannii bacteremia. Infect Chemother 45(3):325\u2013330","journal-title":"Infect Chemother"},{"issue":"6","key":"4668_CR38","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1086\/517954","volume":"28","author":"NY Lee","year":"2007","unstructured":"Lee NY, Lee HC, Ko NY, Chang CM, Shih HI, Wu CJ et al (2007) Clinical and Economic Impact of Multidrug Resistance in Nosocomial Acinetobacter baumannii Bacteremia. Infect Control Hosp Epidemiol 28(6):713\u2013719","journal-title":"Infect Control Hosp Epidemiol"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-023-04668-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-023-04668-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-023-04668-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T08:04:32Z","timestamp":1697702672000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-023-04668-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,28]]},"references-count":38,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["4668"],"URL":"https:\/\/doi.org\/10.1007\/s10096-023-04668-9","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,28]]},"assertion":[{"value":"5 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The studies was approved by the Ethical Committee of Zhongshan People\u2019s Hospital (grant number: K2021-113).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}