{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:44:51Z","timestamp":1790171091718,"version":"4.1.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T00:00:00Z","timestamp":1698278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T00:00:00Z","timestamp":1698278400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001773","name":"University of New South Wales","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001773","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Aortitis is a life-threatening, manifestation of chronic Q fever. We report a series of 5 patients with Q fever aortitis who have presented to our hospital in tropical Australia since 2019. All diagnoses were confirmed with polymerase chain reaction (PCR) testing of aortic tissue. Only one had a previous diagnosis of acute Q fever, and none had classical high-risk exposures that might increase clinical suspicion for the infection. All patients underwent surgery: one died and 3 had significant complications. Q fever aortitis may be underdiagnosed; clinicians should consider testing for <jats:italic>Coxiella burnetii<\/jats:italic> in people with aortic pathology in endemic areas.<\/jats:p>","DOI":"10.1007\/s10096-023-04687-6","type":"journal-article","created":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T15:02:38Z","timestamp":1698332558000},"page":"1537-1541","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Increased recognition of Q fever aortitis as a chronic manifestation of Q fever in tropical North Queensland, Australia"],"prefix":"10.1007","volume":"42","author":[{"given":"Cody","family":"Price","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Palesy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Corbitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charith","family":"Galappaththy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1423-3839","authenticated-orcid":false,"given":"Josh","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,26]]},"reference":[{"issue":"2","key":"4687_CR1","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1097\/00005792-200003000-00005","volume":"79","author":"D Raoult","year":"2000","unstructured":"Raoult D, Tissot-Dupont H, Foucault C, Gouvernet J, Fournier PE, Bernit E et al (2000) Q fever 1985\u20131998. Clinical and epidemiologic features of 1,383 infections. Medicine 79(2):109\u201323 (Baltimore)","journal-title":"Medicine"},{"key":"4687_CR2","unstructured":"Australian Immunisation Handbook (2021) Q fever. Canberra: Australian Government. Department of Health and Aged Care.\u00a0https:\/\/immunisationhandbook.health.gov.au\/contents\/vaccine-preventablediseases\/q-fever"},{"key":"4687_CR3","doi-asserted-by":"publisher","unstructured":"Tozer S, Wood C, Si D, Nissen M, Sloots T, Lambert S (2020) The improving state of Q fever surveillance. A review of Queensland notifications, 2003\u20132017.\u00a0Commun Dis Intell 2018:44. https:\/\/doi.org\/10.33321\/cdi.2020.44.48","DOI":"10.33321\/cdi.2020.44.48"},{"issue":"4","key":"4687_CR4","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1017\/S0950268816002843","volume":"145","author":"TS Sloan-Gardner","year":"2017","unstructured":"Sloan-Gardner TS, Massey PD, Hutchinson P, Knope K, Fearnley E (2017) Trends and risk factors for human Q fever in Australia, 1991\u20132014. Epidemiol Infect 145(4):787\u2013795","journal-title":"Epidemiol Infect"},{"issue":"5","key":"4687_CR5","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1128\/JCM.03221-13","volume":"52","author":"LM Kampschreur","year":"2014","unstructured":"Kampschreur LM, Delsing CE, Groenwold RH, Wegdam-Blans MC, Bleeker-Rovers CP, de Jager-Leclercq MG et al (2014) Chronic Q fever in the Netherlands 5 years after the start of the Q fever epidemic: results from the Dutch chronic Q fever database. J Clin Microbiol 52(5):1637\u20131643","journal-title":"J Clin Microbiol"},{"key":"4687_CR6","doi-asserted-by":"publisher","unstructured":"Graves SR, Islam A, Webb LD, Marsh I, Plain K, Westman M et al (2022) An O-specific polysaccharide\/tetanus toxoid conjugate vaccine induces protection in guinea pigs against virulent challenge with Coxiella burnetii.\u00a0Vaccines (Basel) 10(9):1393. https:\/\/doi.org\/10.3390\/vaccines10091393","DOI":"10.3390\/vaccines10091393"},{"issue":"1","key":"4687_CR7","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1128\/CMR.00045-16","volume":"30","author":"C Eldin","year":"2017","unstructured":"Eldin C, Melenotte C, Mediannikov O, Ghigo E, Million M, Edouard S et al (2017) From Q fever to Coxiella burnetii infection: a paradigm change. Clin Microbiol Rev 30(1):115\u2013190","journal-title":"Clin Microbiol Rev"},{"issue":"12","key":"4687_CR8","doi-asserted-by":"publisher","first-page":"e2810","DOI":"10.1097\/MD.0000000000002810","volume":"95","author":"C Eldin","year":"2016","unstructured":"Eldin C, Mailhe M, Lions C, Carrieri P, Safi H, Brouqui P et al (2016) Treatment and prophylactic strategy for Coxiella burnetii infection of aneurysms and vascular grafts: a retrospective cohort study. Medicine 95(12):e2810 (Baltimore)","journal-title":"Medicine"},{"issue":"3","key":"4687_CR9","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.jinf.2011.12.014","volume":"64","author":"MC Wegdam-Blans","year":"2012","unstructured":"Wegdam-Blans MC, Kampschreur LM, Delsing CE, Bleeker-Rovers CP, Sprong T, van Kasteren ME et al (2012) Chronic Q fever: review of the literature and a proposal of new diagnostic criteria. J Infect 64(3):247\u2013259","journal-title":"J Infect"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-023-04687-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-023-04687-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-023-04687-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T10:08:19Z","timestamp":1700042899000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-023-04687-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,26]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["4687"],"URL":"https:\/\/doi.org\/10.1007\/s10096-023-04687-6","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,26]]},"assertion":[{"value":"13 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Far North Queensland Human Research Ethics Committee provided ethical approval for the study (EX\/2023\/QCH\/95302\u20131707QA).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"As the retrospective data were de-identified, the Far North Queensland Human Research Ethics Committee waived the requirement for informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate and publish"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}