{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T10:32:14Z","timestamp":1794047534170,"version":"4.8.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T00:00:00Z","timestamp":1719187200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T00:00:00Z","timestamp":1719187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1007\/s10096-024-04826-7","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T12:02:02Z","timestamp":1719230522000},"page":"1667-1671","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Chloramphenicol treatment revisited \u2013 demographics, clinical characteristics, and outcomes of hospitalized patients"],"prefix":"10.1007","volume":"43","author":[{"given":"Eli","family":"Ben-Chetrit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alon","family":"Bnaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orit Wolfovitz","family":"Barchad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koral","family":"Vedder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Katz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,24]]},"reference":[{"key":"4826_CR1","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1093\/clinids\/3.3.479","volume":"3","author":"HM Feder Jr","year":"1981","unstructured":"Feder HM Jr., Osier C, Maderazo EG (1981) Chloramphenicol: a review of its use in clinical practice. Rev Infect Dis 3:479\u2013491","journal-title":"Rev Infect Dis"},{"key":"4826_CR2","first-page":"Cd008625","volume":"2014","author":"Y Leibovici-Weissman","year":"2014","unstructured":"Leibovici-Weissman Y, Neuberger A, Bitterman R, Sinclair D, Salam MA, Paul M (2014) Antimicrobial drugs for treating cholera. Cochrane Database Syst Rev 2014:Cd008625","journal-title":"Cochrane Database Syst Rev"},{"key":"4826_CR3","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s12887-021-02497-3","volume":"21","author":"P Khadka","year":"2021","unstructured":"Khadka P, Thapaliya J, Thapa S (2021) Susceptibility pattern of Salmonella enterica against commonly prescribed antibiotics, to febrile-pediatric cases, in low-income countries. BMC Pediatr 21:38","journal-title":"BMC Pediatr"},{"key":"4826_CR4","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1179\/027249303225007752","volume":"23","author":"DG Fuller","year":"2003","unstructured":"Fuller DG, Duke T, Shann F, Curtis N (2003) Antibiotic treatment for bacterial meningitis in children in developing countries. Ann Trop Paediatr 23:233\u2013253","journal-title":"Ann Trop Paediatr"},{"key":"4826_CR5","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1177\/0049475517710397","volume":"47","author":"ER Bregani","year":"2017","unstructured":"Bregani ER, Conti M, Valcarenghi C (2017) Pre-hospital oily chloramphenicol treatment in meningitis outbreaks in low resources environments. Trop Doct 47:328\u2013331","journal-title":"Trop Doct"},{"issue":"4","key":"4826_CR6","first-page":"Cd001832","volume":"2007","author":"K Prasad","year":"2007","unstructured":"Prasad K, Kumar A, Gupta PK, Singhal T (2007) Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis. Cochrane Database Syst Rev 2007(4):Cd001832","journal-title":"Cochrane Database Syst Rev"},{"key":"4826_CR7","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/S1474-4422(08)70139-X","volume":"7","author":"M Scarborough","year":"2008","unstructured":"Scarborough M, Thwaites GE (2008) The diagnosis and management of acute bacterial meningitis in resource-poor settings. Lancet Neurol 7:637\u2013648","journal-title":"Lancet Neurol"},{"key":"4826_CR8","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1093\/jac\/dku530","volume":"70","author":"N Eliakim-Raz","year":"2015","unstructured":"Eliakim-Raz N, Lador A, Leibovici-Weissman Y, Elbaz M, Paul M, Leibovici L (2015) Efficacy and safety of chloramphenicol: joining the revival of old antibiotics? Systematic review and meta-analysis of randomized controlled trials. J Antimicrob Chemother 70:979\u2013996","journal-title":"J Antimicrob Chemother"},{"key":"4826_CR9","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1056\/NEJM196506032722201","volume":"272","author":"JL Scott","year":"1965","unstructured":"Scott JL, Finegold SM, Belkin GA, Lawrence JS (1965) A controlled double-blind study of the hematologic toxicity of chloramphenicol. N Engl J Med 272:1137\u20131142","journal-title":"N Engl J Med"},{"key":"4826_CR10","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1001\/archinte.1970.00310080078010","volume":"126","author":"AA Yunis","year":"1970","unstructured":"Yunis AA, Smith US, Restrepo A (1970) Reversible bone marrow suppression from chloramphenicol. A consequence of mitochondrial injury. Arch Intern Med 126:272\u2013275","journal-title":"Arch Intern Med"},{"key":"4826_CR11","first-page":"225","volume":"10","author":"AA Yunis","year":"1973","unstructured":"Yunis AA (1973) Chloramphenicol-induced bone marrow suppression. Semin Hematol 10:225\u2013234","journal-title":"Semin Hematol"},{"key":"4826_CR12","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.7326\/0003-4819-33-6-1459","volume":"33","author":"ML Rich","year":"1950","unstructured":"Rich ML, Ritterhoff RJ, Hoffmann RJ (1950) A fatal case of aplastic anemia following chloramphenicol (chloromycetin) therapy. Ann Intern Med 33:1459\u20131467","journal-title":"Ann Intern Med"},{"key":"4826_CR13","first-page":"27","volume":"17","author":"O Nitzan","year":"2015","unstructured":"Nitzan O, Kennes Y, Colodner R, Saliba W, Edelstein IH, Raz R et al (2015) Chloramphenicol use and susceptibility patterns in Israel: a national survey. Isr Med Assoc J 17:27\u201331","journal-title":"Isr Med Assoc J"},{"key":"4826_CR14","doi-asserted-by":"crossref","unstructured":"Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H et al (2017) International ERS\/ESICM\/ESCMID\/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia. Guidelines for the management of hospital-acquired pneumonia (HAP)\/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociaci\u00f3n Latinoamericana del T\u00f3rax (ALAT). 50:1700582","DOI":"10.1183\/13993003.00582-2017"},{"key":"4826_CR15","doi-asserted-by":"publisher","first-page":"e45","DOI":"10.1164\/rccm.201908-1581ST","volume":"200","author":"JP Metlay","year":"2019","unstructured":"Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K et al (2019) Diagnosis and treatment of adults with community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med 200:e45\u2013e67","journal-title":"Am J Respir Crit Care Med"},{"key":"4826_CR16","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1093\/cid\/ciw353","volume":"63","author":"AC Kalil","year":"2016","unstructured":"Kalil AC, Metersky ML, Klompas M, Muscedere J, Sweeney DA, Palmer LB et al (2016) Management of adults with hospital-acquired and ventilator-associated Pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis 63:e61\u2013e111","journal-title":"Clin Infect Dis"},{"key":"4826_CR17","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1002\/phar.2209","volume":"39","author":"BT Tsuji","year":"2019","unstructured":"Tsuji BT, Pogue JM, Zavascki AP, Paul M, Daikos GL, Forrest A et al (2019) International Consensus guidelines for the optimal use of the polymyxins: endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for anti-infective pharmacology (ISAP), society of critical Care Medicine (SCCM), and Society of Infectious diseases pharmacists (SIDP). Pharmacotherapy 39:10\u201339","journal-title":"Pharmacotherapy"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04826-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-024-04826-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04826-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T07:05:05Z","timestamp":1721459105000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-024-04826-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,24]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["4826"],"URL":"https:\/\/doi.org\/10.1007\/s10096-024-04826-7","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,24]]},"assertion":[{"value":"7 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This study was approved by the Shaare Zedek Medical Center Institutional Review Board (Helsinki Committee, #0176-20-SZMC).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics appproval"}}]}}