{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:28:25Z","timestamp":1786980505101,"version":"build-2736575974"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T00:00:00Z","timestamp":1714694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T00:00:00Z","timestamp":1714694400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Joint project of Chongqing Health Commission and Science and Technology Bureau","award":["2023MSXM018"],"award-info":[{"award-number":["2023MSXM018"]}]},{"name":"Yongchuan Natural Science Foundation","award":["2021yc-jckx20053"],"award-info":[{"award-number":["2021yc-jckx20053"]}]},{"name":"Talent introduction project of Yongchuan Hospital of Chongqing Medical University","award":["YJYJ202004 and YJYJ202005"],"award-info":[{"award-number":["YJYJ202004 and YJYJ202005"]}]},{"name":"Program for Youth Innovation in Future Medicine, Chongqing Medical University","award":["W0113"],"award-info":[{"award-number":["W0113"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1007\/s10096-024-04841-8","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T09:01:34Z","timestamp":1714726894000},"page":"1309-1318","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["In vitro and in vivo activity of ceftazidime\/avibactam and aztreonam alone or in combination against mcr-9, serine- and metallo-\u03b2-lactamases\u2013co-producing carbapenem-resistant Enterobacter cloacae complex"],"prefix":"10.1007","volume":"43","author":[{"given":"Wengang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longjin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhang","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaixin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunli","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xushan","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunjiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7854-0515","authenticated-orcid":false,"given":"Xiaoli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,3]]},"reference":[{"issue":"6","key":"4841_CR1","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/S1473-3099(19)30210-5","volume":"19","author":"F Perez","year":"2019","unstructured":"Perez F, Bonomo RA (2019) Carbapenem-resistant Enterobacteriaceae: global action required. Lancet Infect Dis 19(6):561\u2013562. https:\/\/doi.org\/10.1016\/S1473-3099(19)30210-5","journal-title":"Lancet Infect Dis"},{"key":"4841_CR2","doi-asserted-by":"publisher","unstructured":"Davin-Regli A, Lavigne J-P, Pag\u00e8s J-M (2019) Enterobacter spp.: update on taxonomy, clinical aspects, and emerging Antimicrobial Resistance. Clin Microbiol Rev 32(4). https:\/\/doi.org\/10.1128\/CMR.00002-19","DOI":"10.1128\/CMR.00002-19"},{"issue":"1","key":"4841_CR3","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1186\/s12879-021-06250-0","volume":"21","author":"J Chen","year":"2021","unstructured":"Chen J, Tian S, Nian H, Wang R, Li F, Jiang N, Chu Y (2021) Carbapenem-resistant Enterobacter cloacae complex in a tertiary hospital in Northeast China, 2010\u20132019. BMC Infect Dis 21(1):611. https:\/\/doi.org\/10.1186\/s12879-021-06250-0","journal-title":"BMC Infect Dis"},{"key":"4841_CR4","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.3389\/fmicb.2018.01597","volume":"9","author":"C Jin","year":"2018","unstructured":"Jin C, Zhang J, Wang Q, Chen H, Wang X, Zhang Y, Wang H (2018) Molecular characterization of Carbapenem-Resistant Enterobacter cloacae in 11 Chinese cities. Front Microbiol 9:1597. https:\/\/doi.org\/10.3389\/fmicb.2018.01597","journal-title":"Front Microbiol"},{"issue":"4","key":"4841_CR5","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1093\/jac\/dku482","volume":"70","author":"TM Gruber","year":"2015","unstructured":"Gruber TM, G\u00f6ttig S, Mark L, Christ S, Kempf VAJ, Wichelhaus TA, Hamprecht A (2015) Pathogenicity of pan-drug-resistant Serratia marcescens harbouring blaNDM-1. J Antimicrob Chemother 70(4):1026\u20131030. https:\/\/doi.org\/10.1093\/jac\/dku482","journal-title":"J Antimicrob Chemother"},{"issue":"2","key":"4841_CR6","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1128\/AAC.03938-14","volume":"59","author":"D Biedenbach","year":"2015","unstructured":"Biedenbach D, Bouchillon S, Hackel M, Hoban D, Kazmierczak K, Hawser S, Badal R (2015) Dissemination of NDM metallo-\u03b2-lactamase genes among clinical isolates of Enterobacteriaceae collected during the SMART global surveillance study from 2008 to 2012. Antimicrob Agents Chemother 59(2):826\u2013830. https:\/\/doi.org\/10.1128\/AAC.03938-14","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"4841_CR7","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.idc.2016.02.005","volume":"30","author":"KS Kaye","year":"2016","unstructured":"Kaye KS, Pogue JM, Tran TB, Nation RL, Li J (2016) Agents of last Resort: Polymyxin Resistance. Infect Dis Clin North Am 30(2):391\u2013414. https:\/\/doi.org\/10.1016\/j.idc.2016.02.005","journal-title":"Infect Dis Clin North Am"},{"issue":"2","key":"4841_CR8","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","volume":"16","author":"Y-Y Liu","year":"2016","unstructured":"Liu Y-Y, Wang Y, Walsh TR, Yi L-X, Zhang R, Spencer J, Doi Y, Tian G, Dong B, Huang X, Yu L-F, Gu D, Ren H, Chen X, Lv L, He D, Zhou H, Liang Z, Liu J-H, Shen J (2016) Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis 16(2):161\u2013168. https:\/\/doi.org\/10.1016\/S1473-3099(15)00424-7","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"4841_CR9","doi-asserted-by":"publisher","first-page":"2897","DOI":"10.1007\/s11033-021-06307-y","volume":"48","author":"NH Hussein","year":"2021","unstructured":"Hussein NH, Al-Kadmy IMS, Taha BM, Hussein JD (2021) Mobilized colistin resistance (mcr) genes from 1 to 10: a comprehensive review. Mol Biol Rep 48(3):2897\u20132907. https:\/\/doi.org\/10.1007\/s11033-021-06307-y","journal-title":"Mol Biol Rep"},{"issue":"11","key":"4841_CR10","doi-asserted-by":"publisher","first-page":"3087","DOI":"10.1093\/jac\/dkaa205","volume":"75","author":"Z Ling","year":"2020","unstructured":"Ling Z, Yin W, Shen Z, Wang Y, Shen J, Walsh TR (2020) Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9. J Antimicrob Chemother 75(11):3087\u20133095. https:\/\/doi.org\/10.1093\/jac\/dkaa205","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"4841_CR11","doi-asserted-by":"publisher","first-page":"8113","DOI":"10.1038\/s41598-020-65106-w","volume":"10","author":"Y Li","year":"2020","unstructured":"Li Y, Dai X, Zeng J, Gao Y, Zhang Z, Zhang L (2020) Characterization of the global distribution and diversified plasmid reservoirs of the colistin resistance gene mcr-9. Sci Rep 10(1):8113. https:\/\/doi.org\/10.1038\/s41598-020-65106-w","journal-title":"Sci Rep"},{"key":"4841_CR12","doi-asserted-by":"publisher","first-page":"756201","DOI":"10.3389\/fmicb.2021.756201","volume":"12","author":"Z Liu","year":"2021","unstructured":"Liu Z, Hang X, Xiao X, Chu W, Li X, Liu Y, Li X, Zhou Q, Li J (2021) Co-occurrence of bla NDM-1 and mcr-9 in a conjugative IncHI2\/HI2A plasmid from a bloodstream infection-causing carbapenem-resistant Klebsiella pneumoniae. Front Microbiol 12:756201. https:\/\/doi.org\/10.3389\/fmicb.2021.756201","journal-title":"Front Microbiol"},{"issue":"3","key":"4841_CR13","doi-asserted-by":"publisher","first-page":"e0030221","DOI":"10.1128\/mSphere.00302-21","volume":"6","author":"S Simoni","year":"2021","unstructured":"Simoni S, Mingoia M, Brenciani A, Carelli M, Lle\u00f2 MM, Malerba G, Vignaroli C (2021) First IncHI2 plasmid carrying mcr-9.1, blaVIM-1, and double copies of blaKPC-3 in a Multidrug-Resistant Escherichia coli Human isolate. mSphere 6(3):e0030221. https:\/\/doi.org\/10.1128\/mSphere.00302-21","journal-title":"mSphere"},{"issue":"4","key":"4841_CR14","doi-asserted-by":"publisher","first-page":"106645","DOI":"10.1016\/j.ijantimicag.2022.106645","volume":"60","author":"H Zhou","year":"2022","unstructured":"Zhou H, Wang S, Wu Y, Dong N, Ju X, Cai C, Li R, Li Y, Liu C, Lu J, Chan EW-C, Chen S, Zhang R, Shen Z (2022) Carriage of the mcr-9 and mcr-10 genes in clinical strains of the Enterobacter cloacae complex in China: a prevalence and molecular epidemiology study. Int J Antimicrob Agents 60(4):106645. https:\/\/doi.org\/10.1016\/j.ijantimicag.2022.106645","journal-title":"Int J Antimicrob Agents"},{"key":"4841_CR15","doi-asserted-by":"publisher","first-page":"1032833","DOI":"10.3389\/fmicb.2022.1032833","volume":"13","author":"S Jiang","year":"2022","unstructured":"Jiang S, Wang X, Yu H, Zhang J, Wang J, Li J, Li X, Hu K, Gong X, Gou X, Yang Y, Li C, Zhang X (2022) Molecular antibiotic resistance mechanisms and co-transmission of the mcr-9 and metallo-\u03b2-lactamase genes in carbapenem-resistant Enterobacter cloacae complex. Front Microbiol 13:1032833. https:\/\/doi.org\/10.3389\/fmicb.2022.1032833","journal-title":"Front Microbiol"},{"key":"4841_CR16","doi-asserted-by":"publisher","first-page":"7107","DOI":"10.2147\/IDR.S385240","volume":"15","author":"G Lu","year":"2022","unstructured":"Lu G, Tang H, Xia Z, Yang W, Xu H, Liu Z, Ni S, Wang Z, Shen J (2022) In vitro and in vivo antimicrobial activities of Ceftazidime\/Avibactam alone or in combination with Aztreonam against Carbapenem-Resistant Enterobacterales. Infect Drug Resist 15:7107\u20137116. https:\/\/doi.org\/10.2147\/IDR.S385240","journal-title":"Infect Drug Resist"},{"issue":"1","key":"4841_CR17","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1186\/s12879-018-3294-3","volume":"18","author":"X Gong","year":"2018","unstructured":"Gong X, Zhang J, Su S, Fu Y, Bao M, Wang Y, Zhang X (2018) Molecular characterization and epidemiology of carbapenem non-susceptible Enterobacteriaceae isolated from the eastern region of Heilongjiang Province, China. BMC Infect Dis 18(1):417. https:\/\/doi.org\/10.1186\/s12879-018-3294-3","journal-title":"BMC Infect Dis"},{"issue":"1","key":"4841_CR18","doi-asserted-by":"publisher","first-page":"e0058521","DOI":"10.1128\/spectrum.00585-21","volume":"9","author":"MM Montero","year":"2021","unstructured":"Montero MM, Domene Ochoa S, L\u00f3pez-Causap\u00e9 C, Luque S, Sorl\u00ed L, Campillo N, L\u00f3pez Montesinos I, Padilla E, Prim N, Angulo-Brunet A, Grau S, Oliver A, Horcajada JP (2021) Time-kill evaluation of antibiotic combinations containing ceftazidime-avibactam against extensively drug-resistant Pseudomonas aeruginosa and their potential role against Ceftazidime-Avibactam-Resistant isolates. Microbiol Spectr 9(1):e0058521. https:\/\/doi.org\/10.1128\/spectrum.00585-21","journal-title":"Microbiol Spectr"},{"key":"4841_CR19","doi-asserted-by":"publisher","first-page":"3171","DOI":"10.2147\/IDR.S408228","volume":"16","author":"J Kuai","year":"2023","unstructured":"Kuai J, Zhang Y, Lu B, Chen H, Zhang Y, Li H, Wang Y, Wang Q, Wang H, Wang X (2023) In vitro synergistic activity of Ceftazidime-Avibactam in Combination with Aztreonam or Meropenem Against Clinical enterobacterales Producing blaKPC or blaNDM. Infect Drug Resist 16:3171\u20133182. https:\/\/doi.org\/10.2147\/IDR.S408228","journal-title":"Infect Drug Resist"},{"issue":"1","key":"4841_CR20","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.jmii.2016.01.003","volume":"51","author":"H Yang","year":"2018","unstructured":"Yang H, Chen G, Hu L, Liu Y, Cheng J, Ye Y, Li J (2018) Enhanced efficacy of imipenem-colistin combination therapy against multiple-drug-resistant Enterobacter cloacae: in vitro activity and a Galleria mellonella model. J Microbiol Immunol Infect 51(1):70\u201375. https:\/\/doi.org\/10.1016\/j.jmii.2016.01.003","journal-title":"J Microbiol Immunol Infect"},{"issue":"1","key":"4841_CR21","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1080\/14787210.2022.2153117","volume":"21","author":"X Li","year":"2023","unstructured":"Li X, Chen Z, Jiao J, Wang S, Wang Y, Wu W, Yang H, Lou H (2023) In vitro and in vivo activity of meropenem\u2009+\u2009avibactam against MBL-producing carbapenem-resistant Klebsiella pneumoniae. Expert Rev Anti Infect Ther 21(1):91\u201398. https:\/\/doi.org\/10.1080\/14787210.2022.2153117","journal-title":"Expert Rev Anti Infect Ther"},{"issue":"9","key":"4841_CR22","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.1093\/jac\/dkz228","volume":"74","author":"T Idowu","year":"2019","unstructured":"Idowu T, Ammeter D, Arthur G, Zhanel GG, Schweizer F (2019) Potentiation of \u03b2-lactam antibiotics and \u03b2-lactam\/\u03b2-lactamase inhibitor combinations against MDR and XDR Pseudomonas aeruginosa using non-ribosomal tobramycin-cyclam conjugates. J Antimicrob Chemother 74(9):2640\u20132648. https:\/\/doi.org\/10.1093\/jac\/dkz228","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"4841_CR23","doi-asserted-by":"publisher","first-page":"105852","DOI":"10.1016\/j.ijantimicag.2019.11.009","volume":"55","author":"J Borjan","year":"2020","unstructured":"Borjan J, Meyer KA, Shields RK, Wenzler E (2020) Activity of ceftazidime-avibactam alone and in combination with polymyxin B against carbapenem-resistant Klebsiella pneumoniae in a tandem in vitro time-kill\/in vivo Galleria mellonella survival model analysis. Int J Antimicrob Agents 55(1):105852. https:\/\/doi.org\/10.1016\/j.ijantimicag.2019.11.009","journal-title":"Int J Antimicrob Agents"},{"issue":"1","key":"4841_CR24","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1089\/mdr.2016.0293","volume":"24","author":"N Manning","year":"2018","unstructured":"Manning N, Balabanian G, Rose M, Landman D, Quale J (2018) Activity of Ceftazidime-Avibactam against clinical isolates of Klebsiella pneumoniae, including KPC-Carrying isolates, endemic to New York City. Microb Drug Resist 24(1):35\u201339. https:\/\/doi.org\/10.1089\/mdr.2016.0293","journal-title":"Microb Drug Resist"},{"issue":"2","key":"4841_CR25","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1093\/jac\/dkx419","volume":"73","author":"S Nath","year":"2018","unstructured":"Nath S, Moussavi F, Abraham D, Landman D, Quale J (2018) In vitro and in vivo activity of single and dual antimicrobial agents against KPC-producing Klebsiella pneumoniae. J Antimicrob Chemother 73(2):431\u2013436. https:\/\/doi.org\/10.1093\/jac\/dkx419","journal-title":"J Antimicrob Chemother"},{"key":"4841_CR26","doi-asserted-by":"publisher","unstructured":"Shields RK, Nguyen MH, Hao B, Kline EG, Clancy CJ (2018) Colistin does not potentiate ceftazidime-avibactam killing of Carbapenem-Resistant Enterobacteriaceae in Vitro or suppress emergence of Ceftazidime-Avibactam Resistance. Antimicrob Agents Chemother 62(8). https:\/\/doi.org\/10.1128\/AAC.01018-18","DOI":"10.1128\/AAC.01018-18"},{"issue":"2","key":"4841_CR27","doi-asserted-by":"publisher","first-page":"ofaa011","DOI":"10.1093\/ofid\/ofaa011","volume":"7","author":"M Falcone","year":"2020","unstructured":"Falcone M, Tiseo G, Antonelli A, Giordano C, Di Pilato V, Bertolucci P, Parisio EM, Leonildi A, Aiezza N, Baccani I, Tagliaferri E, Righi L, Forni S, Sani S, Mechi MT, Pieralli F, Barnini S, Rossolini GM, Menichetti F (2020) Clinical features and outcomes of Bloodstream infections caused by New Delhi Metallo-\u03b2-Lactamase-producing enterobacterales during a Regional Outbreak. Open Forum Infect Dis 7(2):ofaa011. https:\/\/doi.org\/10.1093\/ofid\/ofaa011","journal-title":"Open Forum Infect Dis"},{"issue":"7","key":"4841_CR28","doi-asserted-by":"publisher","first-page":"4239","DOI":"10.1128\/AAC.00206-15","volume":"59","author":"DJ Biedenbach","year":"2015","unstructured":"Biedenbach DJ, Kazmierczak K, Bouchillon SK, Sahm DF, Bradford PA (2015) In vitro activity of aztreonam-avibactam against a global collection of Gram-negative pathogens from 2012 and 2013. Antimicrob Agents Chemother 59(7):4239\u20134248. https:\/\/doi.org\/10.1128\/AAC.00206-15","journal-title":"Antimicrob Agents Chemother"},{"key":"4841_CR29","doi-asserted-by":"publisher","unstructured":"Karlowsky JA, Kazmierczak KM, de Jonge BLM, Hackel MA, Sahm DF, Bradford PA (2017) In Vitro Activity of Aztreonam-Avibactam against Enterobacteriaceae and Pseudomonas aeruginosa isolated by Clinical Laboratories in 40 countries from 2012 to 2015. Antimicrob Agents Chemother 61(9). https:\/\/doi.org\/10.1128\/AAC.00472-17","DOI":"10.1128\/AAC.00472-17"},{"key":"4841_CR30","doi-asserted-by":"publisher","unstructured":"Sader HS, Mendes RE, Pfaller MA, Shortridge D, Flamm RK, Castanheira M (2018) Antimicrobial Activities of Aztreonam-Avibactam and Comparator Agents against Contemporary (2016) Clinical Enterobacteriaceae Isolates. Antimicrob Agents Chemother 62 (1) https:\/\/doi.org\/10.1128\/AAC.01856-17","DOI":"10.1128\/AAC.01856-17"},{"issue":"4","key":"4841_CR31","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1093\/jac\/dkaa531","volume":"76","author":"A Bhatnagar","year":"2021","unstructured":"Bhatnagar A, Ransom EM, Machado M-J, Boyd S, Reese N, Anderson K, Lonsway D, Elkins CA, Rasheed JK, Patel JB, Karlsson M, Brown AC, Lutgring JD (2021) Assessing the in vitro impact of ceftazidime on aztreonam\/avibactam susceptibility testing for highly resistant MBL-producing enterobacterales. J Antimicrob Chemother 76(4):979\u2013983. https:\/\/doi.org\/10.1093\/jac\/dkaa531","journal-title":"J Antimicrob Chemother"},{"key":"4841_CR32","doi-asserted-by":"publisher","unstructured":"Shields RK, Nguyen MH, Chen L, Press EG, Potoski BA, Marini RV, Doi Y, Kreiswirth BN, Clancy CJ (2017) Ceftazidime-Avibactam is Superior to Other Treatment regimens against Carbapenem-resistant Klebsiella pneumoniae Bacteremia. Antimicrob Agents Chemother 61(8). https:\/\/doi.org\/10.1128\/AAC.00883-17","DOI":"10.1128\/AAC.00883-17"},{"issue":"2","key":"4841_CR33","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1093\/cid\/cix783","volume":"66","author":"D van Duin","year":"2018","unstructured":"van Duin D, Lok JJ, Earley M, Cober E, Richter SS, Perez F, Salata RA, Kalayjian RC, Watkins RR, Doi Y, Kaye KS, Fowler VG, Paterson DL, Bonomo RA, Evans S (2018) Colistin Versus Ceftazidime-Avibactam in the treatment of infections due to Carbapenem-Resistant Enterobacteriaceae. Clin Infect Dis 66(2):163\u2013171. https:\/\/doi.org\/10.1093\/cid\/cix783","journal-title":"Clin Infect Dis"},{"key":"4841_CR34","doi-asserted-by":"publisher","unstructured":"Marshall S, Hujer AM, Rojas LJ, Papp-Wallace KM, Humphries RM, Spellberg B, Hujer KM, Marshall EK, Rudin SD, Perez F, Wilson BM, Wasserman RB, Chikowski L, Paterson DL, Vila AJ, van Duin D, Kreiswirth BN, Chambers HF, Fowler VG, Jacobs MR, Pulse ME, Weiss WJ, Bonomo RA (2017) Can Ceftazidime-Avibactam and Aztreonam Overcome \u03b2-Lactam resistance conferred by Metallo-\u03b2-Lactamases in Enterobacteriaceae? Antimicrob Agents Chemother 61(4). https:\/\/doi.org\/10.1128\/AAC.02243-16","DOI":"10.1128\/AAC.02243-16"},{"issue":"5","key":"4841_CR35","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/j.ijantimicag.2018.07.011","volume":"52","author":"LM Avery","year":"2018","unstructured":"Avery LM, Nicolau DP (2018) Assessing the in vitro activity of ceftazidime\/avibactam and aztreonam among carbapenemase-producing Enterobacteriaceae: defining the zone of hope. Int J Antimicrob Agents 52(5):688\u2013691. https:\/\/doi.org\/10.1016\/j.ijantimicag.2018.07.011","journal-title":"Int J Antimicrob Agents"},{"issue":"8","key":"4841_CR36","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.1007\/s10096-021-04197-3","volume":"40","author":"S Maraki","year":"2021","unstructured":"Maraki S, Mavromanolaki VE, Moraitis P, Stafylaki D, Kasimati A, Magkafouraki E, Scoulica E (2021) Ceftazidime-avibactam, meropenen-vaborbactam, and imipenem-relebactam in combination with aztreonam against multidrug-resistant, metallo-\u03b2-lactamase-producing Klebsiella pneumoniae. Eur J Clin Microbiol Infect Dis 40(8):1755\u20131759. https:\/\/doi.org\/10.1007\/s10096-021-04197-3","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"4841_CR37","doi-asserted-by":"publisher","first-page":"34","DOI":"10.4103\/ijmm.IJMM_19_189","volume":"37","author":"AK Pragasam","year":"2019","unstructured":"Pragasam AK, Veeraraghavan B, Shankar BA, Bakthavatchalam YD, Mathuram A, George B, Chacko B, Korula P, Anandan S (2019) Will ceftazidime\/avibactam plus aztreonam be effective for NDM and OXA-48-Like producing organisms: lessons learnt from in vitro study. Indian J Med Microbiol 37(1):34\u201341. https:\/\/doi.org\/10.4103\/ijmm.IJMM_19_189","journal-title":"Indian J Med Microbiol"},{"issue":"3","key":"4841_CR38","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1080\/21505594.2015.1135289","volume":"7","author":"CJ-Y Tsai","year":"2016","unstructured":"Tsai CJ-Y, Loh JMS, Proft T (2016) Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing. Virulence 7(3):214\u2013229. https:\/\/doi.org\/10.1080\/21505594.2015.1135289","journal-title":"Virulence"},{"issue":"11","key":"4841_CR39","doi-asserted-by":"publisher","first-page":"7007","DOI":"10.1128\/AAC.02662-14","volume":"58","author":"SH MacVane","year":"2014","unstructured":"MacVane SH, Crandon JL, Nichols WW, Nicolau DP (2014) Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-\u03b2-lactamase-producing Enterobacteriaceae in a murine thigh infection model. Antimicrob Agents Chemother 58(11):7007\u20137009. https:\/\/doi.org\/10.1128\/AAC.02662-14","journal-title":"Antimicrob Agents Chemother"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04841-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-024-04841-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04841-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T10:04:27Z","timestamp":1721383467000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-024-04841-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,3]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["4841"],"URL":"https:\/\/doi.org\/10.1007\/s10096-024-04841-8","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,3]]},"assertion":[{"value":"4 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}