{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:46:46Z","timestamp":1792003606458,"version":"4.4.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T00:00:00Z","timestamp":1722643200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T00:00:00Z","timestamp":1722643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The vaginal microbiota offers valuable insights into women\u2019s sexual health and the risk of developing sexually transmitted infections (STIs) and bacterial vaginosis. Despite the public health implications of changes in the vaginal environment, existing data on this topic remain sparse.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Following the PRISMA statement guidelines, we consulted five bibliographic databases, focusing on five main daily habits and behaviors. We included only studies published up to October 2023, investigating the influence of personal hygiene, sexual behaviors, hormonal contraception, smoking, alcohol consumption, and psychosocial stress on the vaginal microbiota using next-generation sequencing.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Based on our inclusion criteria, we incorporated 37 studies into this review. Hormonal contraception and personal hygiene were found to promote eubiosis of the vaginal microbiota. In contrast, sexual behaviors, smoking, alcohol consumption, and psychosocial stress were associated with an increased susceptibility to bacterial vaginosis, STIs, and severe pelvic inflammatory diseases due to a modified vaginal microbiota. Black ethnicity emerged as a confounding factor, with this population showing unstable vaginal microbiota. Oral contraception and a stable male sexual partner were found to favor <jats:italic>Lactobacillus<\/jats:italic> colonization, acting as a protective factor. Conversely, non-hormonal contraception and unprotected or non-penile\/vaginal sexual activity increased the incidence of vaginal inflammation and bacterial vaginosis by disturbing the vaginal microbiota and reducing <jats:italic>Lactobacillus<\/jats:italic> abundance.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Daily habits and lifestyle can influence the composition of the vaginal microbiota, thereby affecting vaginal health. Disturbances in the vaginal microbiota could be associated factors for STIs and vaginosis. Therefore, prioritizing more appropriate management of the vaginal microbiota is crucial.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10096-024-04915-7","type":"journal-article","created":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T10:02:09Z","timestamp":1722679329000},"page":"1869-1881","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["The association between lifestyle factors and the composition of the vaginal microbiota: a review"],"prefix":"10.1007","volume":"43","author":[{"given":"Madjid","family":"Morsli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Gimenez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Magnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Salipante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Huberlant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Letouzey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9484-0304","authenticated-orcid":false,"given":"Jean-Philippe","family":"Lavigne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,3]]},"reference":[{"key":"4915_CR1","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1177\/1745505717731011","volume":"13","author":"Y Chen","year":"2017","unstructured":"Chen Y, Bruning E, Rubino J, Eder SE (2017) Role of female intimate hygiene in vulvovaginal health: global hygiene practices and product usage. Women\u2019s Heal 13:58\u201367. https:\/\/doi.org\/10.1177\/1745505717731011","journal-title":"Women\u2019s Heal"},{"key":"4915_CR2","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1136\/gutjnl-2018-315988","volume":"67","author":"J Wang","year":"2018","unstructured":"Wang J, Zheng J, Shi W, Du nan, Xu X, Zhang Y et al (2018) Gut microbiota dysbiosis of maternal and neonatal microbiota associated with gestational diabetes mellitus. Gut 67:1614\u20131625. https:\/\/doi.org\/10.1136\/gutjnl-2018-315988","journal-title":"Gut"},{"key":"4915_CR3","doi-asserted-by":"publisher","unstructured":"Shen L, Zhang W, Yuan Y (2022) Vaginal microecological characteristics of women in different physiological and pathological period. Front Cell Infect Microbiol 12:959793. https:\/\/doi.org\/10.3389\/fcimb.2022.959793","DOI":"10.3389\/fcimb.2022.959793"},{"key":"4915_CR4","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3003605","author":"P Gajer","year":"2012","unstructured":"Gajer P, Brotman RM, Bai G, Sakamoto J, Sch\u00fctte UME, Zhong X et al (2012) Temporal Dynamics Hum Vaginal Microbiota.\u00a0Sci Transl Med 4:132ra52 https:\/\/doi.org\/10.1126\/scitranslmed.3003605","journal-title":"Temporal Dynamics Hum Vaginal Microbiota"},{"key":"4915_CR5","doi-asserted-by":"publisher","unstructured":"Kwon MS, Lee HK (2022) Host and Microbiome Interplay shapes the Vaginal Microenvironment. 13:1\u201313. https:\/\/doi.org\/10.3389\/fimmu.2022.919728","DOI":"10.3389\/fimmu.2022.919728"},{"key":"4915_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12934-020-01464-4","volume":"19","author":"WJY Chee","year":"2020","unstructured":"Chee WJY, Chew SY, Than LTL (2020) Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health. Microb Cell Fact 19:1\u201324. https:\/\/doi.org\/10.1186\/s12934-020-01464-4","journal-title":"Microb Cell Fact"},{"key":"4915_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fendo.2018.00568","volume":"9","author":"E Amabebe","year":"2018","unstructured":"Amabebe E, Anumba DOC (2018) Psychosocial Stress, Cortisol Levels, and Maintenance of Vaginal Health. Front Endocrinol (Lausanne) 9:568. https:\/\/doi.org\/10.3389\/fendo.2018.00568","journal-title":"Maintenance Vaginal Health"},{"key":"4915_CR8","doi-asserted-by":"publisher","unstructured":"Costantini PE, Firrincieli A, Fedi S, Parolin C, Viti C, Cappelletti M et al (2021) Insight into phenotypic and genotypic differences between vaginal Lactobacillus crispatus BC5 and Lactobacillus gasseri BC12 to unravel nutritional and stress factors influencing their metabolic activity. Microb Genom 7:000575. https:\/\/doi.org\/10.1099\/mgen.0.000575","DOI":"10.1099\/mgen.0.000575"},{"key":"4915_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/nu12020419","volume":"12","author":"A Barrientos-Dur\u00e1n","year":"2020","unstructured":"Barrientos-Dur\u00e1n A, Fuentes-L\u00f3pez A, de Salazar A, Plaza-D\u00edaz J, Garc\u00eda F (2020) Reviewing the composition of vaginal microbiota: inclusion of nutrition and probiotic factors in the maintenance of eubiosis. Nutrients 12:1\u201330. https:\/\/doi.org\/10.3390\/nu12020419","journal-title":"Nutrients"},{"key":"4915_CR10","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.clnu.2020.01.011.Dietary","volume":"176","author":"S Rupak Shivakoti","year":"2020","unstructured":"Barrientos-Dur\u00e1n A, Fuentes-L\u00f3pez A, de Salazar A, Plaza-D\u00edaz J, Garc\u00eda F (2020) Reviewing the composition of vaginal microbiota: Inclusion of nutrition and probiotic factors in the maintenance of eubiosis. Nutrients 12: 419. https:\/\/doi.org\/10.1016\/j.clnu.2020.01.011.Dietary","journal-title":"HHS Public Access Physiol Behav"},{"key":"4915_CR11","doi-asserted-by":"publisher","unstructured":"McKinnon LR, Achilles SL, Bradshaw CS, Burgener A, Crucitti T, Fredricks DN et al (2019) The evolving facets of bacterial vaginosis: implications for HIV Transmission. AIDS Res Hum Retroviruses 35:219-228. https:\/\/doi.org\/10.1089\/AID.2018.0304","DOI":"10.1089\/AID.2018.0304"},{"key":"4915_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12941-020-0347-4","volume":"19","author":"N Kalia","year":"2020","unstructured":"Kalia N, Singh J, Kaur M (2020) Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review. Ann Clin Microbiol Antimicrob 19:1\u201319. https:\/\/doi.org\/10.1186\/s12941-020-0347-4","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"4915_CR13","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1055\/s-0033-1361822","volume":"32","author":"H Sharma","year":"2014","unstructured":"Sharma H, Tal R, Clark NA, Segars JH (2014) Microbiota and pelvic inflammatory disease. Semin Reprod Med 32:43\u201349. https:\/\/doi.org\/10.1055\/s-0033-1361822","journal-title":"Semin Reprod Med"},{"key":"4915_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fcimb.2021.698840","volume":"311","author":"H Chen","year":"2021","unstructured":"Chen H, Wang L, Zhao L, Luo L, Min S, Wen Y et al (2021) Alterations of vaginal microbiota in women with infertility and Chlamydia trachomatis infection. Front Cell Infect Microbiol 311:1\u201311. https:\/\/doi.org\/10.3389\/fcimb.2021.698840","journal-title":"Front Cell Infect Microbiol"},{"key":"4915_CR15","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1016\/j.rbmo.2022.06.008","volume":"45","author":"P Peuranp\u00e4\u00e4","year":"2022","unstructured":"Peuranp\u00e4\u00e4 P, Holster T, Saqib S, Kalliala I, Tiitinen A, Salonen A et al (2022) Female reproductive tract microbiota and recurrent pregnancy loss: a nested case-control study. Reprod Biomed Online 45:1021\u20131031. https:\/\/doi.org\/10.1016\/j.rbmo.2022.06.008","journal-title":"Reprod Biomed Online"},{"key":"4915_CR16","doi-asserted-by":"publisher","unstructured":"Rethlefsen ML, Kirtley S, Waffenschmidt S, Ayala AP, Moher D, Page MJ et al (2021) PRISMA-S: an extension to the PRISMA Statement for reporting literature searches in systematic reviews. Syst Rev 10:39. https:\/\/doi.org\/10.1186\/S13643-020-01542-Z","DOI":"10.1186\/S13643-020-01542-Z"},{"key":"4915_CR17","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1089\/aid.2013.0251","volume":"30","author":"S Sivapalasingam","year":"2014","unstructured":"Sivapalasingam S, McClelland RS, Ravel J, Ahmed A, Cleland CM, Gajer P et al (2014) An effective intervention to reduce intravaginal practices among HIV-1 uninfected Kenyan women. AIDS Res Hum Retroviruses 30:1046\u20131054. https:\/\/doi.org\/10.1089\/aid.2013.0251","journal-title":"AIDS Res Hum Retroviruses"},{"key":"4915_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12866-019-1545-0","volume":"19","author":"C Van Der Veer","year":"2019","unstructured":"Van Der Veer C, Bruisten SM, Van Houdt R, Matser AA, Tachedjian G, Van De Wijgert JHHM et al (2019) Effects of an over-the-counter lactic-acid containing intra-vaginal douching product on the vaginal microbiota. BMC Microbiol 19:1\u201313. https:\/\/doi.org\/10.1186\/s12866-019-1545-0","journal-title":"BMC Microbiol"},{"key":"4915_CR19","doi-asserted-by":"publisher","unstructured":"Brown SE, He X, Shardell MD, Ravel J, Ghanem KG, Zenilman JM et al (2022) Douching cessation and molecular bacterial vaginosis: a reanalysis of archived specimens. Sex Transm Infect 99:156\u2013161. https:\/\/doi.org\/10.1136\/sextrans-2022-055459","DOI":"10.1136\/sextrans-2022-055459"},{"key":"4915_CR20","doi-asserted-by":"publisher","unstructured":"Christin-Maitre S (2022) La contraception \u00e0 travers le monde [Worldwide contraception]. Med Sci (Paris) 38:457-463. https:\/\/doi.org\/10.1051\/medsci\/2022058","DOI":"10.1051\/medsci\/2022058"},{"key":"4915_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/msphere.00593-20","volume":"5","author":"SD Song","year":"2020","unstructured":"Song SD, Acharya KD, Zhu JE, Deveney CM, Walther-Antonio MRS, Tetel MJ et al (2020) Daily Vaginal Microbiota fluctuations Associated with Natural Hormonal cycle, contraceptives, Diet, and Exercise. mSphere 5:1\u201314. https:\/\/doi.org\/10.1128\/msphere.00593-20","journal-title":"mSphere"},{"key":"4915_CR22","doi-asserted-by":"publisher","first-page":"218","DOI":"10.2174\/1874285801812010218","volume":"12","author":"SE Fosch","year":"2018","unstructured":"Fosch SE, Ficoseco CA, Marchesi A, Cocucci S, Nader-Macias MEF, Perazzi BE (2018) Contraception: influence on vaginal microbiota and identification of Vaginal Lactobacilli using MALDI-TOF MS and 16S rDNA sequencing. Open Microbiol J 12:218\u2013229. https:\/\/doi.org\/10.2174\/1874285801812010218","journal-title":"Open Microbiol J"},{"key":"4915_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-020-19382-9","volume":"11","author":"C Balle","year":"2020","unstructured":"Balle C, Konstantinus IN, Jaumdally SZ, Havyarimana E, Lennard K, Esra R et al (2020) Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial. Nat Commun 11:1\u201315. https:\/\/doi.org\/10.1038\/s41467-020-19382-9","journal-title":"Nat Commun"},{"key":"4915_CR24","doi-asserted-by":"publisher","unstructured":"Brooks JP, Edwards DJ, Blithe DL, Fettweis JM, Serrano MG, Sheth NU et al (2017) Effects of combined oral contraceptives, depot medroxyprogesterone acetate and the levonorgestrel-releasing intrauterine system on the vaginal microbiome. Contraception. 2017 95:405-413.  https:\/\/doi.org\/10.1016\/j.contraception.2016.11.006","DOI":"10.1016\/j.contraception.2016.11.006"},{"key":"4915_CR25","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.contraception.2014.04.006","volume":"90","author":"JC Jacobson","year":"2014","unstructured":"Jacobson JC, Turok DK, Dermish AI, Nygaard IE, Settles ML (2014) Vaginal microbiome changes with levonorgestrel intrauterine system placement. Contraception 90:130\u2013135. https:\/\/doi.org\/10.1016\/j.contraception.2014.04.006","journal-title":"Contraception"},{"key":"4915_CR26","doi-asserted-by":"publisher","unstructured":"Wessels JM, Lajoie J, Hay Cooper MIJ, Omollo K, Felker AM, Vitali D et al (2019) Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice. DMM Dis Model Mech 12:dmm039669. https:\/\/doi.org\/10.1242\/dmm.039669","DOI":"10.1242\/dmm.039669"},{"key":"4915_CR27","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1080\/22221751.2018.1563458","volume":"8","author":"L Yang","year":"2019","unstructured":"Yang L, Hao Y, Hu J, Kelly D, Li H, Brown S et al (2019) Differential effects of depot medroxyprogesterone acetate administration on vaginal microbiome in hispanic White and Black women. Emerg Microbes Infect 8:197\u2013210. https:\/\/doi.org\/10.1080\/22221751.2018.1563458","journal-title":"Emerg Microbes Infect"},{"key":"4915_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fimmu.2021.760504","volume":"12","author":"S Dabee","year":"2021","unstructured":"Dabee S, Tanko RF, Brown BP, Bunjun R, Balle C, Feng C et al (2021) Comparison of female genital Tract Cytokine and Microbiota signatures Induced by initiation of intramuscular DMPA and NET-EN Hormonal Contraceptives - a prospective cohort analysis. Front Immunol 12:1\u201314. https:\/\/doi.org\/10.3389\/fimmu.2021.760504","journal-title":"Front Immunol"},{"key":"4915_CR29","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.contraception.2017.05.017","volume":"96","author":"CM Bassis","year":"2017","unstructured":"Bassis CM, Allsworth JE, Wahl HN, Sack DE, Young VB, Bell JD (2017) Effects of intrauterine contraception on the vaginal microbiota. Contraception 96:189\u2013195. https:\/\/doi.org\/10.1016\/j.contraception.2017.05.017","journal-title":"Contraception"},{"key":"4915_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0171856","volume":"12","author":"LA Vodstrcil","year":"2017","unstructured":"Vodstrcil LA, Twin J, Garland SM, Fairley CK, Hocking JS, Law MG et al (2017) The influence of sexual activity on the vaginal microbiota and Gardnerella vaginalis clade diversity in young women. PLoS ONE 12:1\u201315. https:\/\/doi.org\/10.1371\/journal.pone.0171856","journal-title":"PLoS ONE"},{"key":"4915_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2334-14-471","volume":"14","author":"RM Brotman","year":"2014","unstructured":"Brotman RM, He X, Gajer P, Fadrosh D, Sharma E, Mongodin EF et al (2014) Association between cigarette smoking and the vaginal microbiota: a pilot study. BMC Infect Dis 14:1\u201311. https:\/\/doi.org\/10.1186\/1471-2334-14-471","journal-title":"BMC Infect Dis"},{"key":"4915_CR32","doi-asserted-by":"publisher","first-page":"0","DOI":"10.1177\/11769343221110663","volume":"18","author":"WT Yang","year":"2022","unstructured":"Yang WT, Chiang I, Tseng CH, Cheng C, Lin JH, Liu PY et al (2022) Metagenomic sequencing and histology on a chronic wound identified Epstein-Barr Virus-Associated Lymphoma. Evol Bioinform Online 18:11769343221110663. https:\/\/doi.org\/10.1177\/11769343221110663","journal-title":"Evol Bioinforma"},{"key":"4915_CR33","doi-asserted-by":"publisher","unstructured":"34.\tMckee KS, Carter KA, Bassis C, Young VB, Reed B, Harper DM, Ruffin MT 4th, Bell JD (2020) The vaginal microbiota, high-risk human papillomavirus infection, and cervical cytology: results from a population-based study. Gynecol Pelvic Med 3: 18. https:\/\/doi.org\/10.21037\/gpm-20-10.","DOI":"10.21037\/gpm-20-10."},{"key":"4915_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0181135","volume":"12","author":"H Borgdorff","year":"2017","unstructured":"Borgdorff H, Van Der Veer C, Van Houdt R, Alberts CJ, De Vries HJ, Bruisten SM et al (2017) The association between ethnicity and vaginal microbiota composition in Amsterdam, the Netherlands. PLoS ONE 12:1\u201317. https:\/\/doi.org\/10.1371\/journal.pone.0181135","journal-title":"PLoS ONE"},{"key":"4915_CR35","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1097\/OLQ.0000000000001066","volume":"46","author":"SE Brown","year":"2019","unstructured":"33. Brown SE, Schwartz JA, Robinson CK, O\u2019Hanlon DE, Bradford LL, He X et al (2019) The vaginal microbiota and behavioral factors Associated with Genital Candida albicans Detection in Reproductive-Age women. Sex Transm Dis 46:753\u2013758. https:\/\/doi.org\/10.1097\/OLQ.0000000000001066","journal-title":"Sex Transm Dis"},{"key":"4915_CR36","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1097\/AOG.0B013E31827075AC","volume":"120","author":"CM Mitchell","year":"2012","unstructured":"Mitchell CM, Fredricks DN, Winer RL, Koutsky L (2012) Effect of sexual debut on vaginal microbiota in a cohort of Young Women. Obstet Gynecol 120:1306. https:\/\/doi.org\/10.1097\/AOG.0B013E31827075AC","journal-title":"Obstet Gynecol"},{"key":"4915_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0116894","volume":"10","author":"SD Mehta","year":"2015","unstructured":"Mehta SD, Donovan B, Weber KM, Cohen M, Ravel J, Gajer P et al (2015) The vaginal microbiota over an 8- to 10-year period in a cohort of HIV-infected and HIV-uninfected women. PLoS ONE 10:1\u201321. https:\/\/doi.org\/10.1371\/journal.pone.0116894","journal-title":"PLoS ONE"},{"key":"4915_CR38","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1097\/OLQ.0000000000001204","volume":"47","author":"C Marconi","year":"2020","unstructured":"Marconi C, El-Zein M, Ravel J, Ma B, Lima MD, Carvalho NS et al (2020) Characterization of the vaginal microbiome in women of reproductive age from 5 regions in Brazil. Sex Transm Dis 47:562\u2013569. https:\/\/doi.org\/10.1097\/OLQ.0000000000001204","journal-title":"Sex Transm Dis"},{"key":"4915_CR39","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1111\/1471-0528.15981","volume":"127","author":"JC Borgogna","year":"2020","unstructured":"Borgogna JC, Shardell MD, Santori EK, Nelson TM, Rath JM, Glover ED et al (2020) The vaginal metabolome and microbiota of cervical HPV-positive and HPV-negative women: a cross-sectional analysis. BJOG 127:182\u2013192. https:\/\/doi.org\/10.1111\/1471-0528.15981","journal-title":"BJOG Int J Obstet Gynaecol"},{"key":"4915_CR40","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1136\/SEXTRANS-2020-054824","volume":"198","author":"J Novak","year":"2022","unstructured":"Novak J, Ravel J, Ma B, Ferreira CST, Trist\u00e3o Ada, Silva R (2022) Characteristics associated with Lactobacillus iners-dominated vaginal microbiota. Sex Transm Infect 198:353\u2013359. https:\/\/doi.org\/10.1136\/SEXTRANS-2020-054824","journal-title":"Sex Transm Infect"},{"key":"4915_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0187612","volume":"12","author":"JM Wessels","year":"2017","unstructured":"Wessels JM, Lajoie J, Vitali D, Omollo K, Kimani J, Oyugi J et al (2017) Association of high-risk sexual behaviour with diversity of the vaginal microbiota and abundance of Lactobacillus. PLoS ONE 12:1\u201323. https:\/\/doi.org\/10.1371\/journal.pone.0187612","journal-title":"PLoS ONE"},{"key":"4915_CR42","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1136\/sextrans-2017-053133.Lactobacillus","volume":"176","author":"B van Robin","year":"2018","unstructured":"van Houdt R, Ma B, Bruisten SM, Speksnijder ACL, Ravel J, de Vries HJC (2018) Lactobacillus iners-dominated vaginal microbiota is associated with increased susceptibility to Chlamydia trachomatis infection in Dutch women: a case-control study. Sec Transm Infect 94:117-123. https:\/\/doi.org\/10.1136\/sextrans-2017-053133.","journal-title":"Behav"},{"key":"4915_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40168-016-0161-6","volume":"4","author":"M Zozaya","year":"2016","unstructured":"Zozaya M, Ferris MJ, Siren JD, Lillis R, Myers L, Nsuami MJ et al (2016) Bacterial communities in penile skin, male urethra, and vaginas of heterosexual couples with and without bacterial vaginosis. Microbiome 4:1\u201310. https:\/\/doi.org\/10.1186\/s40168-016-0161-6","journal-title":"Microbiome"},{"key":"4915_CR44","doi-asserted-by":"publisher","unstructured":"Xia Y, Feng Y, Qin T, Zhao X, Lu J, Ma C (2022) Characteristics of vaginal Microbiome in Reproductive-Age females with HPV infection in Xinjiang, China. Evid Based Complement Alternat Med 2022:7332628. https:\/\/doi.org\/10.1155\/2022\/7332628","DOI":"10.1155\/2022\/7332628"},{"key":"4915_CR45","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1111\/1471-0528.16430","volume":"128","author":"LK Ratten","year":"2021","unstructured":"Ratten LK, Plummer EL, Murray GL, Danielewski J, Fairley CK, Garland SM et al (2021) Sex is associated with the persistence of non-optimal vaginal microbiota following treatment for bacterial vaginosis: a prospective cohort study. BJOG 128:756\u2013767. https:\/\/doi.org\/10.1111\/1471-0528.16430","journal-title":"BJOG Int J Obstet Gynaecol"},{"key":"4915_CR46","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-019-55929-7","volume":"9","author":"EL Plummer","year":"2019","unstructured":"Plummer EL, Vodstrcil LA, Fairley CK, Tabrizi SN, Garland SM, Law MG et al (2019) Sexual practices have a significant impact on the vaginal microbiota of women who have sex with women. Sci Rep 9:1\u201314. https:\/\/doi.org\/10.1038\/s41598-019-55929-7","journal-title":"Sci Rep"},{"key":"4915_CR47","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.jadohealth.2019.01.010","volume":"1","author":"KL Nunn","year":"2019","unstructured":"Nunn KL, Ridenhour BJ, Chester EM, Vitzthum VJ, Fortenberry JD, Forney LJ, Vaginal Glycogen (2019) Not Estradiol, is Associated with Vaginal Bacterial Community Composition in Black Adolescent women. J Adolesc Heal 65:130\u2013138. https:\/\/doi.org\/10.1016\/j.jadohealth.2019.01.010","journal-title":"J Adolesc Heal"},{"key":"4915_CR48","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.anaerobe.2018.10.001","volume":"54","author":"A Matsumoto","year":"2018","unstructured":"Matsumoto A, Yamagishi Y, Miyamoto K, Oka K, Takahashi M, Mikamo H (2018) Characterization of the vaginal microbiota of Japanese women. Anaerobe 54:172\u2013177. https:\/\/doi.org\/10.1016\/j.anaerobe.2018.10.001","journal-title":"Anaerobe"},{"key":"4915_CR49","doi-asserted-by":"crossref","unstructured":"Sivro A, Mwatelah R, Kambaran C, Gebrebrhan H, Becker MG, Ma H et al (2020) Sex Work Is Associated With Increased Vaginal Microbiome Diversity in Young Women From Mombasa, Kenya. J Acquir Immune Defic Syndr 85: 79-87. https:\/\/doi.org\/10.1097\/QAI.0000000000002406","DOI":"10.1097\/QAI.0000000000002406"},{"key":"4915_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0191625","volume":"13","author":"N Noyes","year":"2018","unstructured":"Noyes N, Cho KC, Ravel J, Forney LJ, Abdo Z (2018) Associations between sexual habits, menstrual hygiene practices, demographics and the vaginal microbiome as revealed by bayesian network analysis. PLoS ONE 13:1\u201325. https:\/\/doi.org\/10.1371\/journal.pone.0191625","journal-title":"PLoS ONE"},{"key":"4915_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0260813","volume":"16","author":"JLC Borgogna","year":"2021","unstructured":"Borgogna JLC, Anastario M, Firemoon P, Rink E, Ricker A, Ravel J et al (2021) Vaginal microbiota of American Indian women and associations with measures of psychosocial stress. PLoS ONE 16:1\u201326. https:\/\/doi.org\/10.1371\/journal.pone.0260813","journal-title":"PLoS ONE"},{"key":"4915_CR52","doi-asserted-by":"publisher","first-page":"2374","DOI":"10.1093\/aje\/kwab147","volume":"190","author":"R Turpin","year":"2021","unstructured":"Turpin R, Slopen N, Borgogna JLC, Yeoman CJ, He X, Miller RS et al (2021) Perceived stress and molecular bacterial vaginosis in the National Institutes of Health Longitudinal Study of Vaginal Flora. Am J Epidemiol 190:2374\u20132383. https:\/\/doi.org\/10.1093\/aje\/kwab147","journal-title":"Am J Epidemiol"},{"key":"4915_CR53","doi-asserted-by":"publisher","first-page":"2272","DOI":"10.1099\/mic.0.081034-0","volume":"160","author":"JM Fettweis","year":"2014","unstructured":"Fettweis JM, Paul Brooks J, Serrano MG, Sheth NU, Girerd PH, Edwards DJ et al (2014) Differences in vaginal microbiome in African American women versus women of European ancestry. Microbiology (Reading) 160:2272\u20132282. https:\/\/doi.org\/10.1099\/mic.0.081034-0","journal-title":"Microbiol (United Kingdom)"},{"key":"4915_CR54","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-14943-3","volume":"8","author":"TM Nelson","year":"2018","unstructured":"Nelson TM, Borgogna JC, Michalek RD, Roberts DW, Rath JM, Glover ED et al (2018) Cigarette smoking is associated with an altered vaginal tract metabolomic profile. Sci Rep 8:1\u201313. https:\/\/doi.org\/10.1038\/s41598-017-14943-3","journal-title":"Sci Rep"},{"key":"4915_CR55","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1093\/infdis\/jiy243","volume":"218","author":"CA Muzny","year":"2018","unstructured":"Muzny CA, Blanchard E, Taylor CM, Aaron KJ, Talluri R, Griswold ME et al (2018) Identification of key Bacteria involved in the induction of Incident bacterial vaginosis: a prospective study. J Infect Dis 218:966\u2013978. https:\/\/doi.org\/10.1093\/infdis\/jiy243","journal-title":"J Infect Dis"},{"key":"4915_CR56","doi-asserted-by":"publisher","unstructured":"Balakrishnan SN, Yamang H, Lorenz MC, Chew SY, Than LTL (2022) Role of vaginal mucosa, host immunity and microbiota in Vulvovaginal Candidiasis. Pathog 11:618. https:\/\/doi.org\/10.3390\/PATHOGENS11060618","DOI":"10.3390\/PATHOGENS11060618"},{"key":"4915_CR57","doi-asserted-by":"publisher","unstructured":"Valenti P, Rosa L, Capobianco D, Lepanto MS, Schiavi E, Cutone A et al (2018) Role of Lactobacilli and Lactoferrin in the Mucosal Cervicovaginal Defense. Front Immunol 9:376. https:\/\/doi.org\/10.3389\/FIMMU.2018.00376","DOI":"10.3389\/FIMMU.2018.00376"},{"key":"4915_CR58","doi-asserted-by":"publisher","unstructured":"Zhao C, Li Y, Chen B, Yue K, Su Z, Xu J et al (2023) Mycobiome Study reveals different pathogens of vulvovaginal candidiasis shape characteristic vaginal bacteriome. Microbiol Spectr 11: e0315222. https:\/\/doi.org\/10.1128\/SPECTRUM.03152-22","DOI":"10.1128\/SPECTRUM.03152-22"},{"key":"4915_CR59","doi-asserted-by":"publisher","unstructured":"Abou Chacra L, Fenollar F (2021) Exploring the global vaginal microbiome and its impact on human health. Microb Pathog 160:105172. https:\/\/doi.org\/10.1016\/J.MICPATH.2021.105172","DOI":"10.1016\/J.MICPATH.2021.105172"},{"key":"4915_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0080254","volume":"8","author":"CA Muzny","year":"2013","unstructured":"Muzny CA, Sunesara IR, Kumar R, Mena LA, Griswold ME, Martin DH et al (2013) Characterization of the vaginal microbiota among sexual risk behavior groups of women with bacterial vaginosis. PLoS ONE 8:1\u201311. https:\/\/doi.org\/10.1371\/journal.pone.0080254","journal-title":"PLoS ONE"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04915-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-024-04915-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04915-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T16:22:44Z","timestamp":1726503764000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-024-04915-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,3]]},"references-count":60,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["4915"],"URL":"https:\/\/doi.org\/10.1007\/s10096-024-04915-7","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,3]]},"assertion":[{"value":"14 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This is a review study. No ethical approval is required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}